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Neural and Hormonal Systems Everything psychological is simultaneously biological. Phrenology, although seriously misguided, was a tentative step in this direction. Wrong-headed theory (m4.1p46,c2.1p48) in your text. But! These areas in the brain are all interconnected, making the brain the most complex structure in the known universe. The brain is not a computer! This is a common misconception. Neural and Hormonal Systems Neuron: the basic building block of the nervous system. Each consists of a cell body and branching fibres. The dendrites are the bushy, branching extensions that receive messages and conduct impulses toward the cell body. For the biology students: dendrites are complex microtubules, proof that neurons are specializations from simpler cell structures. Axon: the neuron extension that passes messagesthrough its branches to other neurons. Neural and Hormonal Systems Myelin sheath: a layer of fatty tissue which insulates the axon and speeds up the tranmission of neural impulses. After age 25, this sheath deteriorates, leading in extreme cases to multiple sclerosis. Your brain is vastly more complex than a computer, but slower at executing simple responses. Commit Figure 4.2 p48 (c2.2p50)to memory; it is crucial to understanding further material in this course. This will need to be integrated with Web Article 1, because of our new understanding of dendrites. Neural and Hormonal Systems Figure 4.3(mp49, c2.3p51) Action potential. Neurons generate electricity from chemical events: electrically charged ions pump in and out of the axon. The best way to understand how action potential works is to do the Wave, in class, right now! The change in charge is what travels down the axon, not the chemicals themselves. Google [“action potential animation”] Eg: https://www.youtube.com/watch?v=iDgKqJbdiDk Action Potential Neuron stimulation causes a brief change in electrical charge. If strong enough, this produces depolarization and an action potential. This depolarization produces another action potential a little farther along the axon. Gates in this neighbouring area are now open, and sodium ions rush in. The sodium/potassium pump in the cell membrane transports the sodium ions back out of the cell. Action Potential As the action potential continues speedily down the axon, the first section has now completely recharged. Each neuron is a miniature decision-making device performing complex calculations as it receives signals from hundreds, even thousands of other neurons. Excitatory signals push the message forward; inhibitory signals stop it cold. All-or-none. Neurons either fire, or they don't. Synaptic Gap Fig. 4.4 mp50, (c2.4p52)to memory; Action potentials travel down the axon until reaching a tiny junction, the synapse. Then, the action potential stimulates the release of neurotransmitter molecules. They cross the synaptic gap and bind to receptor sites on the receiving neuron. This allows ions to enter the recieving neuron and excite or inhibit a new action potential. The sender neuron reabsorbs excess neurotransmitters. This is reuptake. https://www.youtube.com/watch?v=TevNJYyATAM Serotonin & Dopamine Serotonin and dopamine are of the most interest to psychologists, because they have the greatest effects on high brain functions, primarily mood and language. Serotonin is an endogenous opiate, or an endorphin. Morphine, heroine, (and after a conversion at the bloodbrain barrier) alcohol are agonists to serotonin. Dopamine also has several agonists, the best known being lysergic acid diethylamide 25, or LSD. Commit to memory: Fig 4.5 (mp51, c2.5p53) Agonists & Antagonists : Acetylcholine Acetylcholine (Ach) plays a role in learning and memory. In addition, it is the messenger at every junction between motor neurons and skeletal muscles. When Ach is released, the muscle contracts. Curare is an antagonist of Ach, and is used to paralyze fish, and the lips of Hollywood starlets, the wonder of Botox. Commit to memory: Table 4.1 (mp52, c2.1p54) Commit to memory: Fig. 4.6 (mp53, c2.6p55) Hormones are Thoughts Too Fig. 4.8 (mp55, c2.8p57)will be on the exam. The autonomic nervous system controls our glands and the muscles of our internal organs, influencing such functions as glandular activity, heartbeat, and digestion. It may be consciously overridden. The sympathetic nervous system arouses and expends energy. Heartrate, blood pressure, digestion, blood sugar, and perspiration are controlled by it. The parasympathetic system does the opposite. Brains are not Computers The brain has some 40 billion neurons, each connecting with 10,000 other neurons. That creates 400 trillion synapses. And each synapse is its own symphony orchestra of neurotransmitters. No modern, silicon-based microprocessor (like the one in your smart phone) can come close to this level of networking complexity. The best analogy is to consider your brain as a super-Internet. The study of this complex connectivity is called neural networking. Back to Hormones! The endocrine system is the body's slow communications system; a set of glands that secrete hormones into the bloodstream. Hormones are chemical messengers that are manufactured by the endrocrine glands. An example are the corticosteriods, which travel through the bloodstream, and rebuild muscle tissues. After a heavy workout, your hormonal system shifts into high corticosteroid production. For psychologists, the most important gland is the hypothalamus, located in the middle brain. Commit to memory: Fig. 4.11 (mp58,c2.11p60)