
Molecular and Cellular Mechanisms of Reelin Signaling in the Adult
... cognitive impairments associated with disease states. In Chapters 2 and 3 of this dissertation, we describe recent attempts by our lab to elucidate cellular mechanisms of Reelin signaling in the adult brain. To do this, we generated two conditional knockout mutants that lack the obligate downstream ...
... cognitive impairments associated with disease states. In Chapters 2 and 3 of this dissertation, we describe recent attempts by our lab to elucidate cellular mechanisms of Reelin signaling in the adult brain. To do this, we generated two conditional knockout mutants that lack the obligate downstream ...
Leptin Signaling in the Nucleus Tractus Solitarii
... Allyn L. Mark, Khristofor Agassandian, Donald A. Morgan, Xuebo Liu, Martin D. Cassell, Kamal Rahmouni ...
... Allyn L. Mark, Khristofor Agassandian, Donald A. Morgan, Xuebo Liu, Martin D. Cassell, Kamal Rahmouni ...
Anatomy & Physiology I
... Free nerve endings – Bare dendrites – No structural specialization microscopically – Pain, thermal, tickle, itch, some touch Encapsulated nerve endings – Dendrites are enclosed in a connective tissue capsule – Capsule enhances sensitivity or specificity of the receptor – Pressure and vibration ( ...
... Free nerve endings – Bare dendrites – No structural specialization microscopically – Pain, thermal, tickle, itch, some touch Encapsulated nerve endings – Dendrites are enclosed in a connective tissue capsule – Capsule enhances sensitivity or specificity of the receptor – Pressure and vibration ( ...
thesis - ETDA
... dystonia, which results in larger cortical representation areas of the affected body parts and that may affect inhibition (Hallett M, 1998). While many theories are currently being discussed in the literature, very few are consistently supported by findings in dystonic patients. This could mean that ...
... dystonia, which results in larger cortical representation areas of the affected body parts and that may affect inhibition (Hallett M, 1998). While many theories are currently being discussed in the literature, very few are consistently supported by findings in dystonic patients. This could mean that ...
Organization of brainstem nuclei
... Following the original suggestion of Paxinos and Huang (1995), we also acknowledge that the radial arrangement of the human caudal hindbrain with reference to the fourth ventricle (as King, 1980, proposed for the cat) is more tenable than the “quilt” pattern proposed by Olszewski and Baxter (1954). ...
... Following the original suggestion of Paxinos and Huang (1995), we also acknowledge that the radial arrangement of the human caudal hindbrain with reference to the fourth ventricle (as King, 1980, proposed for the cat) is more tenable than the “quilt” pattern proposed by Olszewski and Baxter (1954). ...
the neurobiology of nicotine addiction: bridging the gap from
... and nicotine8,23,24. Much evidence implicates the VTA and its associated efferent and afferent projections as an integrative centre for the psychoactive effects of nicotine. Within the VTA, DA neurons (designated as the A10 DA group), and their associated ascending projections to the nucleus accumbe ...
... and nicotine8,23,24. Much evidence implicates the VTA and its associated efferent and afferent projections as an integrative centre for the psychoactive effects of nicotine. Within the VTA, DA neurons (designated as the A10 DA group), and their associated ascending projections to the nucleus accumbe ...
Organization of the Olfactory and Respiratory Skeleton in the Nose
... fossil mammals. Variability in this complex is suspected to be systematically informative (Cleland, 1862; Allen, 1882; Paulli, 1900a,b,c; Gregory, 1910; Negus, 1958; Moore, 1981; Novacek, 1993). However, few characters are formally scored in cladistic analyses, variability of this system is not well ...
... fossil mammals. Variability in this complex is suspected to be systematically informative (Cleland, 1862; Allen, 1882; Paulli, 1900a,b,c; Gregory, 1910; Negus, 1958; Moore, 1981; Novacek, 1993). However, few characters are formally scored in cladistic analyses, variability of this system is not well ...
Calcium Transients in the Garter Snake Vomeronasal Organ
... selective staining of VN neurons with Ca2⫹ Green after retrograde transport of this dye from their axonal terminals in the accessory olfactory bulb (AOB). Observe the labeling in the cell bodies of mature VN neurons (red arrows) located in the intermediate region of the sensory epithelium. No other ...
... selective staining of VN neurons with Ca2⫹ Green after retrograde transport of this dye from their axonal terminals in the accessory olfactory bulb (AOB). Observe the labeling in the cell bodies of mature VN neurons (red arrows) located in the intermediate region of the sensory epithelium. No other ...
elsevier second proof - Michigan State University
... projects from the accessory olfactory bulb to the amygdala (amg). The medial olfactory tract (MOT) projects to the anterior olfactory nucleus (aon), septum (sep), and medial pallium (mp). The extrabulbar olfactory pathway (EBOP) contains axons of primary olfactory receptor neurons that bypass the ol ...
... projects from the accessory olfactory bulb to the amygdala (amg). The medial olfactory tract (MOT) projects to the anterior olfactory nucleus (aon), septum (sep), and medial pallium (mp). The extrabulbar olfactory pathway (EBOP) contains axons of primary olfactory receptor neurons that bypass the ol ...
2017
... sessions (Saturday, Sunday, Monday, 4:00pm -5:00pm and Tuesday, 12:15-1:30 pm) and workshops aimed at providing new investigators with valuable tools for career success. Credit for the organization of all these activities into a well-coordinated and exciting meeting goes to Ruth Litovsky and the oth ...
... sessions (Saturday, Sunday, Monday, 4:00pm -5:00pm and Tuesday, 12:15-1:30 pm) and workshops aimed at providing new investigators with valuable tools for career success. Credit for the organization of all these activities into a well-coordinated and exciting meeting goes to Ruth Litovsky and the oth ...
THE SUBFORNICAL ORGAN AND AREA POSTREMA MEDIATE
... expenditure and autonomic function via activation of its receptor (ObRb) in nuclei in the central nervous system (CNS). This thesis investigates the involvement of two sensory circumventricular organs (CVOs), the subfornical organ (SFO) and area postrema (AP), in mediating the central effects of lep ...
... expenditure and autonomic function via activation of its receptor (ObRb) in nuclei in the central nervous system (CNS). This thesis investigates the involvement of two sensory circumventricular organs (CVOs), the subfornical organ (SFO) and area postrema (AP), in mediating the central effects of lep ...
REM Sleep - Test Page
... However, to a surprising extent this is not the case. As I review later, REM sleep reappears within hours after some of these lesions. When both parts of the brain remain, signs usually appear on only one side of the cut. This kind of positive evidence is much more easily interpreted than loss of fu ...
... However, to a surprising extent this is not the case. As I review later, REM sleep reappears within hours after some of these lesions. When both parts of the brain remain, signs usually appear on only one side of the cut. This kind of positive evidence is much more easily interpreted than loss of fu ...
Jennifer McFarland - University of Evansville Faculty Web sites
... interpreted to suggest that REM sleep promotes neurogenesis, but this is unlikely. Despite the fact that the exact mechanism by which sleep deprivation reduces neurogenesis in the adult hippocampus is unknown, there is strong evidence supporting glucocorticoid release, due to the stress of chronic s ...
... interpreted to suggest that REM sleep promotes neurogenesis, but this is unlikely. Despite the fact that the exact mechanism by which sleep deprivation reduces neurogenesis in the adult hippocampus is unknown, there is strong evidence supporting glucocorticoid release, due to the stress of chronic s ...
Role of brain-derived neurotrophic factor in Huntington`s disease
... 2.3. Corticostriatal neurons are the main source of striatal BDNF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.4. Cortical BDNF levels depend on striatal integrity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Production of ...
... 2.3. Corticostriatal neurons are the main source of striatal BDNF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.4. Cortical BDNF levels depend on striatal integrity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Production of ...
Mechanisms of Leptin Action and Leptin Resistance
... LRb signaling, feedback inhibition, and the regulation of physiology. Leptin binding to the extracellular domain of LRb, the functional leptin receptor isoform, mediates the activation of the intracellular, LRb-associated Jak2 tyrosine kinase, resulting in Jak2 autophosphorylation on tyrosine residu ...
... LRb signaling, feedback inhibition, and the regulation of physiology. Leptin binding to the extracellular domain of LRb, the functional leptin receptor isoform, mediates the activation of the intracellular, LRb-associated Jak2 tyrosine kinase, resulting in Jak2 autophosphorylation on tyrosine residu ...
The Formation of Specific Synaptic Connections Between Muscle
... least some use of their shoulder. Two used the limb during walking, including elbow movements. None of the limbs was noticeably atrophic. As a group, these frogs were younger at the time of denervation (2 at stage XIV and 1 each at stages XV and XVI, average stage = 14.75). Physiological analysis of ...
... least some use of their shoulder. Two used the limb during walking, including elbow movements. None of the limbs was noticeably atrophic. As a group, these frogs were younger at the time of denervation (2 at stage XIV and 1 each at stages XV and XVI, average stage = 14.75). Physiological analysis of ...
Structure and dynamics of the corticothalamic driver pathway in the
... himself. I hope I can follow his model and also keep this enthusiasm alive for decades. Bert Sakmann’s support before and during my PhD was invaluable and by his supervision I learned how to structure research projects and avoid getting side-tracked on fruitless endeavors. My special thanks go to Al ...
... himself. I hope I can follow his model and also keep this enthusiasm alive for decades. Bert Sakmann’s support before and during my PhD was invaluable and by his supervision I learned how to structure research projects and avoid getting side-tracked on fruitless endeavors. My special thanks go to Al ...
Read as PDF
... motor programs elicited in this manner are predominantly ingestive (Susswein et al., 1996) and are likely to be biting motor programs (Rosen et al., 1997). During carbachol-elicited programs we found that bursts of activity in B66 were out-of-phase with bursts of activity in B4/5 and out-of-phase wi ...
... motor programs elicited in this manner are predominantly ingestive (Susswein et al., 1996) and are likely to be biting motor programs (Rosen et al., 1997). During carbachol-elicited programs we found that bursts of activity in B66 were out-of-phase with bursts of activity in B4/5 and out-of-phase wi ...
Channelrhodopsin

Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.