SACpaper-TMG12-27 FS..
... results also indicate that these different channel types are normally highly active on growth cones extending upon fibronectin (FN) in culture. In addition to testing blockers of SACs, we also tested blockers of transient receptor potential (TRP) channels, as some of these channels are known to be m ...
... results also indicate that these different channel types are normally highly active on growth cones extending upon fibronectin (FN) in culture. In addition to testing blockers of SACs, we also tested blockers of transient receptor potential (TRP) channels, as some of these channels are known to be m ...
Axonal of Kinesin in the Chain Isoforms
... movement of radiolabeled kinesin through optic nerve and tract into the terminals was monitored by immunoprecipitation. Heavy and light chains of kinesin appeared in nerve and tract at times consistent with fast transport. Little or no kinesin moved with slow axonal transport indicating that effecti ...
... movement of radiolabeled kinesin through optic nerve and tract into the terminals was monitored by immunoprecipitation. Heavy and light chains of kinesin appeared in nerve and tract at times consistent with fast transport. Little or no kinesin moved with slow axonal transport indicating that effecti ...
Structural differences in two biochemically-defined
... lamelliform cristae (Fig 2A,B; 3A). Lamelliform cristae are broad and flat, may show throughand-through fenestrations, and are joined to the boundary membrane by numerous crista junctions, to use the terminology of Perkins et al.14 Some of the lamelliform cristae have small vesicular protuberances a ...
... lamelliform cristae (Fig 2A,B; 3A). Lamelliform cristae are broad and flat, may show throughand-through fenestrations, and are joined to the boundary membrane by numerous crista junctions, to use the terminology of Perkins et al.14 Some of the lamelliform cristae have small vesicular protuberances a ...
Mitochondria as a Pharmacological Target
... function, mitochondria are involved in such complex processes as apoptosis and cardioprotection. A rapidly expanding body of literature also suggests that mitochondrial dysfunctions play pivotal roles in neurodegenerative disorders ranging from Parkinson’s to Huntington’s to Alzheimer’s diseases. Mi ...
... function, mitochondria are involved in such complex processes as apoptosis and cardioprotection. A rapidly expanding body of literature also suggests that mitochondrial dysfunctions play pivotal roles in neurodegenerative disorders ranging from Parkinson’s to Huntington’s to Alzheimer’s diseases. Mi ...
Fine structural analysis of extraocular muscle spindles of a two
... Mi-1 HODS. Distal halves of two EOMs obtained from a 2-year-old multiorgan donor were immersionfixed and prepared for electron microscopy. The fine structure of 10 muscle spindles and of 1 "false spindle" was investigated. Rrsui.TS. Extraocular muscle spindles of an infant 2 years of age had 2- to 4 ...
... Mi-1 HODS. Distal halves of two EOMs obtained from a 2-year-old multiorgan donor were immersionfixed and prepared for electron microscopy. The fine structure of 10 muscle spindles and of 1 "false spindle" was investigated. Rrsui.TS. Extraocular muscle spindles of an infant 2 years of age had 2- to 4 ...
Fine structural analysis of extraocular muscle spindles of a
... Mi-1 HODS. Distal halves of two EOMs obtained from a 2-year-old multiorgan donor were immersionfixed and prepared for electron microscopy. The fine structure of 10 muscle spindles and of 1 "false spindle" was investigated. Rrsui.TS. Extraocular muscle spindles of an infant 2 years of age had 2- to 4 ...
... Mi-1 HODS. Distal halves of two EOMs obtained from a 2-year-old multiorgan donor were immersionfixed and prepared for electron microscopy. The fine structure of 10 muscle spindles and of 1 "false spindle" was investigated. Rrsui.TS. Extraocular muscle spindles of an infant 2 years of age had 2- to 4 ...
A role for subplate neurons in the patterning of
... During cerebral cortical development, ingrowing axons from different thalamic nuclei select and invade their cortical targets. The selection of an appropriate target is first evident even before thalamic axons grow into the cortical plate: initially axons accumulate and wait below their cortical tar ...
... During cerebral cortical development, ingrowing axons from different thalamic nuclei select and invade their cortical targets. The selection of an appropriate target is first evident even before thalamic axons grow into the cortical plate: initially axons accumulate and wait below their cortical tar ...
Electron tomography of plant thylakoid membranes
... 1999). For conventional ET, samples are embedded in plastic and sectioned by ultramicrotomy. Although this yields highcontrast images of gross cellular features including membranes, molecular detail is lost. To obtain tomograms of 4– 5nm resolution (Leis et al., 2009), the sample has to be vitrified ...
... 1999). For conventional ET, samples are embedded in plastic and sectioned by ultramicrotomy. Although this yields highcontrast images of gross cellular features including membranes, molecular detail is lost. To obtain tomograms of 4– 5nm resolution (Leis et al., 2009), the sample has to be vitrified ...
Mitochondrial support of persistent presynaptic vesicle mobilization
... Hackenbrock, 1966, 1968; Perkins et al., 2010; Packer, 1960). Under resting conditions, mitochondria have loosely packed matrix and narrow cristae, whereas under conditions of high energy demand the matrix compacts and cristae widen (Hackenbrock, 1966, 1968). These changes appear to reflect, for exa ...
... Hackenbrock, 1966, 1968; Perkins et al., 2010; Packer, 1960). Under resting conditions, mitochondria have loosely packed matrix and narrow cristae, whereas under conditions of high energy demand the matrix compacts and cristae widen (Hackenbrock, 1966, 1968). These changes appear to reflect, for exa ...
Masticatory myosin unveiled - AJP
... two genes, coding for /slow MyHC, expressed in cardiac muscle and in slow or type 1 fibers of skeletal muscles, and for ␣-MyHC, expressed in cardiomyocytes and in specialized skeletal muscles (masticatory, extraocular, and laryngeal), respectively. 3) Only the gene coding for the masticatory or M M ...
... two genes, coding for /slow MyHC, expressed in cardiac muscle and in slow or type 1 fibers of skeletal muscles, and for ␣-MyHC, expressed in cardiomyocytes and in specialized skeletal muscles (masticatory, extraocular, and laryngeal), respectively. 3) Only the gene coding for the masticatory or M M ...
A biomaterials approach to peripheral nerve regeneration: bridging
... Figure 2. Summarized schematic of the structural repair strategies used for improving existing hollow nerve guidance conduits. Repair strategies include the use of intraluminal guidance structures and micro-grooved luminal designs to provide additional structure support and topographical guidance to ...
... Figure 2. Summarized schematic of the structural repair strategies used for improving existing hollow nerve guidance conduits. Repair strategies include the use of intraluminal guidance structures and micro-grooved luminal designs to provide additional structure support and topographical guidance to ...
The Role of Kv7 in Peripheral Neurons
... Peripheral myelinated and unmyelinated axons The axons in the peripheral nervous system (PNS) can be divided into two broad classes the myelinated and the unmyelinated axons. The myelinated axons are organized into several domains - the node of Ranvier, the paranode, the juxtaparanode, and the inter ...
... Peripheral myelinated and unmyelinated axons The axons in the peripheral nervous system (PNS) can be divided into two broad classes the myelinated and the unmyelinated axons. The myelinated axons are organized into several domains - the node of Ranvier, the paranode, the juxtaparanode, and the inter ...
PDF
... differentiation in vivo is that axogenesis in individual neurons precedes their dendrogenesis (Kim and Chiba, 2004; Westerfield et al., 1986). As a result, when dendrites first appear in the embryonic CNS, axons have already laid out basic fascicle organizations. In many animals, a neuropil, the reg ...
... differentiation in vivo is that axogenesis in individual neurons precedes their dendrogenesis (Kim and Chiba, 2004; Westerfield et al., 1986). As a result, when dendrites first appear in the embryonic CNS, axons have already laid out basic fascicle organizations. In many animals, a neuropil, the reg ...
–plasma-membrane junctions by Kv2.1 Induction of stable ER potassium channels
... 2010). Kv2.1 is expressed abundantly in the neuronal soma, suggesting that the channel takes on a non-traditional function that is not related to the regulation of action potentials, which requires a high level of expression – as expected of a structural or scaffolding protein. Indeed, there is a gr ...
... 2010). Kv2.1 is expressed abundantly in the neuronal soma, suggesting that the channel takes on a non-traditional function that is not related to the regulation of action potentials, which requires a high level of expression – as expected of a structural or scaffolding protein. Indeed, there is a gr ...
Induction of stable ER–plasma-membrane junctions by Kv2.1
... 2010). Kv2.1 is expressed abundantly in the neuronal soma, suggesting that the channel takes on a non-traditional function that is not related to the regulation of action potentials, which requires a high level of expression – as expected of a structural or scaffolding protein. Indeed, there is a gr ...
... 2010). Kv2.1 is expressed abundantly in the neuronal soma, suggesting that the channel takes on a non-traditional function that is not related to the regulation of action potentials, which requires a high level of expression – as expected of a structural or scaffolding protein. Indeed, there is a gr ...
The Glia of Caenorhabditis elegans - Shaham Lab
... each providing important contributions towards the activity of the system as a whole. It would be, therefore, surprising if nervous systems comprised only one relevant cell type. Nature seems to agree. Neurons have also been assigned dedicated partners: the glia. Whether cells functioning as glia ex ...
... each providing important contributions towards the activity of the system as a whole. It would be, therefore, surprising if nervous systems comprised only one relevant cell type. Nature seems to agree. Neurons have also been assigned dedicated partners: the glia. Whether cells functioning as glia ex ...
AXOTOMIZED SPINAL COMMISSURAL INTERNEURONS OF THE ADULT FELINE:
... Second, SCI sites contain molecules that inhibit the growth of elongating axons. However, despite this inability to regenerate through traumatic injury sites, many spinal axons have been found to be quite plastic – that is, sprout new connections from uninjured portions of their axons. In addition, ...
... Second, SCI sites contain molecules that inhibit the growth of elongating axons. However, despite this inability to regenerate through traumatic injury sites, many spinal axons have been found to be quite plastic – that is, sprout new connections from uninjured portions of their axons. In addition, ...
1 oxidative capacity distribution in skeletal muscle fibers of the rat
... possibility of determining whether the difference in oxidative capacity is a characteristic shared by the different fiber types or is limited to only some of them. The oxidative capacity of a given volume of a cell is closely related to the product of the oxidative capacity of its mitochondria and i ...
... possibility of determining whether the difference in oxidative capacity is a characteristic shared by the different fiber types or is limited to only some of them. The oxidative capacity of a given volume of a cell is closely related to the product of the oxidative capacity of its mitochondria and i ...
Chromatin Fibers Observed In Situ in Frozen Hydrated Sections
... of cultured cells at metaphase, suggested a liquid organization in which individual nucleosomes had considerable freedom of movement rather than being confined within a fiber. These authors did not, however, examine cyrosections of nuclei in which 30-urn chromatin fibers are observed in conventional ...
... of cultured cells at metaphase, suggested a liquid organization in which individual nucleosomes had considerable freedom of movement rather than being confined within a fiber. These authors did not, however, examine cyrosections of nuclei in which 30-urn chromatin fibers are observed in conventional ...
POTASSIUM IN SOIL – PLANT – HUMAN SYSTEM
... Potassium is one of the main elements which reduce perspiration, makes plants more resistent to frost and drought, to diseases and pests. It improves the quality of the yield and increases the storage time of the crops. It influences in the positive way the formation of the clorophyle. It ensures th ...
... Potassium is one of the main elements which reduce perspiration, makes plants more resistent to frost and drought, to diseases and pests. It improves the quality of the yield and increases the storage time of the crops. It influences in the positive way the formation of the clorophyle. It ensures th ...
Slow Ventricular Conduction in Mice Heterozygous for a
... markedly among different cardiac tissues in patterns that are consistent with the distinct anisotropic conduction properties of each tissue (1, 5, 7). Thus, tissue-specific connexin phenotypes and gap junction distributions appear to be major determinants of the disparate conduction properties of ca ...
... markedly among different cardiac tissues in patterns that are consistent with the distinct anisotropic conduction properties of each tissue (1, 5, 7). Thus, tissue-specific connexin phenotypes and gap junction distributions appear to be major determinants of the disparate conduction properties of ca ...
An evolutionarily conserved mechanism for cAMP elicited axonal
... inability to regenerate nerve fibers is not set in stone. Instead, it can be unlocked by a second injury in nerves elsewhere in the body, the so-called “peripheral nervous system”. This process relies on an enzyme called DLK, which becomes activated in damaged nerve fibers. But how does DLK ‘sense’ ...
... inability to regenerate nerve fibers is not set in stone. Instead, it can be unlocked by a second injury in nerves elsewhere in the body, the so-called “peripheral nervous system”. This process relies on an enzyme called DLK, which becomes activated in damaged nerve fibers. But how does DLK ‘sense’ ...
KATP channels and preconditioning - Philipps
... agonists of G protein-coupled receptors (adenosine, bradykinin, catecholamines and opioids) [6,8–13], succinate dehydrogenase blockers (3-nitropropionic acid) [14], carbonmonoxide releasing molecules [15] and Na+/H+ exchange blockers (cariporide and ethylisopropyl amiloride) [16]. In most cases, PPC ...
... agonists of G protein-coupled receptors (adenosine, bradykinin, catecholamines and opioids) [6,8–13], succinate dehydrogenase blockers (3-nitropropionic acid) [14], carbonmonoxide releasing molecules [15] and Na+/H+ exchange blockers (cariporide and ethylisopropyl amiloride) [16]. In most cases, PPC ...
Caudal Topographic Nucleus Isthmi and the Rostra1
... neurons labeled in Imr, nucleus lentiformis mesencephali, or profundus mesencephali rostralis (PMr). The axons of neurons in those nuclei were reconstructed from serial sections and found to branch widely, sparsely innervating large areas of the tectum. Fourth, the dense thickets are not terminals o ...
... neurons labeled in Imr, nucleus lentiformis mesencephali, or profundus mesencephali rostralis (PMr). The axons of neurons in those nuclei were reconstructed from serial sections and found to branch widely, sparsely innervating large areas of the tectum. Fourth, the dense thickets are not terminals o ...
Node of Ranvier
The nodes of Ranvier also known as myelin sheath gaps, are the gaps (approximately 1 micrometer in length) formed between the myelin sheaths generated by different cells. A myelin sheath is a many-layered coating, largely composed of a fatty substance called myelin, that wraps around the axon of a neuron and very efficiently insulates it. At nodes of Ranvier, the axonal membrane is uninsulated and, therefore, capable of generating electrical activity.