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Neuroscience and Behavior How Neurons Communicate Neurons Term Explanation Application/Example/Extension Neurons are the building blocks, or messengers, which travel throughout the nervous system allowing communication Parts of a Dendrites- the part of a neuron which receives As dendrites grow in size, like a bush growing in size, then Neuron information from other neurons communication between neurons will be quicker because neurotransmitters do not travel very far to the next neuron. Neurons don’t regenerate Axons- part of a neuron where neural impulses take The longest part of a neuron place, which enables information to be sent to other neurons Myelin sheath- insulates, or covers the axon, which When myelin sheath starts to disintegrate, or disappear helps to speed up communication then multiple sclerosis could develop Nodes of Ranvier- are gaps in the myelin sheath Neurotransmitters- chemical messengers that travel across a synapse from one neuron to another influencing whether an action potential will occur Synapse- the gap between neurons that neurotransmitters cross Neurons are able to communicate through an action potential, which is a brief electrical charge that travels through a neuron allowing a neurotransmitter, or messenger, to exit the neuron and go to another neuron Neural Resting potential- each neuron sits, or rests at a - Like the water in your toilet at a constant level waiting to Impulse 70 charge, which is the only time the neuron is be flushed. (action capable of firing an action potential potential) Process Depolarization- a Threshold- through the Think about the threshold as the height requirement to ride Begins message from process of depolarization the an amusement park roller coaster. If you are above the another neuron inside becomes positive; height line then you can ride (same as a charge being causes the inside of once this charge exceeds the above the threshold) allowing an action potential to occur the neuron to threshold, which is the become positive as minimum level of sodium starts to stimulation necessary to enter cause an action potential, then the neuron fires. Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only. Neuroscience and Behavior All-or-none potential- a neuron will fire each Similar to when you fire a gun- the bullet comes out the time with the same amount of intensity same way every time you pull the trigger Process Finishes Repolarization- occurs right after the action potential as potassium moves out of the inside of the cell restoring the inside back to a negative charge Hyperpolarization- occurs right after the process of repolarization because the inside of the cell’s charge becomes too low, or below the -70 charge. Nervous Systems Excitatory messagemakes it more likely the neuron will depolarize, causing an action potential Central nervous system Peripheral nervous system Inhibitory messagemakes it more likely neuron will hyperpolarize, not causing an action potential Think about RE-polarization as RE-storing the charge back to -70 Hyperpolarization A refractory period is similar to the is referred to as a moment after you flush a toilet- until refractory period, the water returns back to its original as during this level you can’t flush again, similar period the neuron to a neuron returning back to -70 can’t fire until the before it can fire another action charge returns back potential to -70 Remember excitatory means to EXCITE- when the neuron becomes excited it fires an action potential. Inhibit means to stop, or slow down an action potential Includes the brain and spinal cord Interneurons- neurons Remember the spinal cord in centrally located in your body located within and only travel and communicate in the central nervous system The Peripheral nervous system connects the body to the central nervous system An example of the somatic nervous system would Parts of the Peripheral Somatic nervous system- part of the peripheral nervous system be moving your arm- you are voluntarily moving Nervous System which controls voluntary your arm movements Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only. Neuroscience and Behavior Autonomic nervous system- part of the peripheral nervous system which controls involuntary movements Parts of the Autonomic Sympathetic nervous systempart of the autonomic nervous nervous system system that speeds up the body Parasympathetic nervous system- part of the autonomic nervous system that calms the body down Neurons and Nerves An example of the autonomic nervous system is your heart rate, which occurs involuntary or automatically An example of the sympathetic nervous system would be your heart racing, or speeding up as you almost get into a car accident. S-ympathetic= S-peed up the body An example of the parasympathetic nervous system would be your heart-rate retuning back to its normal rate as the accident is over. P-utting back heart rate= P-arasympathetic Sensory neurons- are Interneurons- are Motor neurons are neurons neurons that travel neurons that that travel within the peripheral within the peripheral communicate within nervous system; carry nervous system and the central nervous information out to muscles and sense information from system glands, causing movement the environment Reuptake- presynaptic neuron Reuptake process is like a vacuum- the sending Presynaptic neuronneuron that sends, or absorbs back excessive, or neuron sucks back excessive NTs to later be releases a neurotransmitter unused, neurotransmitters in used- if NTs stay in the synapse for a period of the synapse time, then problems could occur, like depression. Postsynaptic neuron- neuron that receives a neurotransmitter Nerves are neural cables, or “roads,” comprised of axons Nerves are like ropes. Ropes are intertwined that are part of peripheral nervous system, which enable with string and nerves are intertwined with communication back to the central nervous system axons. Neural Chain- how the brain communicates with the body Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only. Neuroscience and Behavior Types of Neurotransmitters Afferent nervescarry information TO the central nervous system Neurotransmitter Acetylcholine Dopamine Serotonin Norepinephrine GABA Glutamate Endorphins Sensory neurons- neurons Remember the word SAME that travel within afferent Sensory neurons travel through Afferent nerves nerves and SEND Motor neurons travel through Efferent nerves information to the central nervous system Efferent nervesMotor neurons- neurons carry information that travel within efferent FROM the central nerves and carry information nervous system AWAY from the central nervous system Tie it all together: If you were to put your finger in hot water (1) a sensory neuron would detect this hot water travel through an afferent nerve up the peripheral nervous system, towards the central nervous system where (2) an interneuron would take the information, then the brain would process the information, releasing (3) a motor neuron that would travel through an efferent nerve back down the peripheral nervous system, causing your finger to pull out of the hot water. Function Problems Muscle action, learning, memory Lack of can lead to Alzheimer’s disease Learning, attention, emotion- pleasure Too much dopamine leads to schizophrenia, and too little dopamine could lead to Parkinson’s disease Mood, hunger, sleep, arousal Lack of linked to depression Alertness and arousal Lack of linked to depression Inhibitory neurotransmitter- slows down brain Lack of linked to seizures, tremors, and insomnia activity Major excitatory neurotransmitter- involved Too much could lead to migraines or seizures in memory Pain control and pleasure Too much pain medication could lead to lack of endorphin supply Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only. Neuroscience and Behavior Parts of the Brain Endocrine System Drugs that affect Neurotransmitters Agonist is a drug designed to mimic, or perform the same actions as a neurotransmitter- often used when there is not enough of a neurotransmitter Antagonist is a drug designed to block a neurotransmitter- often used when there is too much of a neurotransmitter The endocrine system is another type of communication system that uses a set of glands which produce hormones (like neurotransmitters) that circulate through the bloodstream, enabling communication. Hypothalamus- part of the brain that links the brain to the endocrine system through control of the pituitary gland Pituitary gland- “master gland” that controls all other glands Thyroid gland- involved in metabolism Adrenal glands- help trigger “fight-or-flight” response Brainstem- oldest part of the brain; responsible for survival; comprised of the hindbrain and midbrain Midbrain- controls certain types of automatic behaviors Hindbrain- an extension of spinal cord involved in blood pressure, heart rate, breathing, and other vital life functions; includes the medulla, reticular formation, cerebellum, and pons Medulla- controls heartbeat and breathing Reticular formation- controls wakefulness and arousal Cerebellum- coordinates movements, balance Pons- coordinates movements on the left and right side of the body; dreams Forebrain- responsible for complex behaviors and mental abilities Hypothalamus- maintains eating, drinking, body temperature Agonist is like a key that fits a lock and is able to unlock it- the same as an agonist fitting the receptor site of a neuron and mimicking the NT Antagonist is like a key that fits a lock but does not turn the lock, hence not opening the door- the key is now stuck in the lock, preventing any other key from entering The endocrine system uses the bloodstream making it much slower than the nervous system, which uses electricity Think of the pituitary gland as “master P” If you were to look at a car seat you would notice that it is positioned to hit the top part of the heard, rather than the brainstem, as this could cause serious-to-fatal injury. “Pay particular (reticular) attention” “Sara-bellum has good balance” Think about playing ping PONg- hitting back and forth as the pons controls right and left movements “The man’s part of the brain”- loves pizza and beer Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only. Neuroscience and Behavior Limbic system- regulates memory, fear, aggression, hunger, and thirst Hippocampus- processes new memories Amygdala- linked to fear and emotion Thalamus- relay center for sensory information except smell Cerebral cortex- most sophisticated area of the brain Cerebral hemispheres- the left and right side of the cerebral cortex Corpus callosum- connects the two hemispheres Split-brain- refers to people who have had their corpus callusum severed/ Roger Sperry found to reduce epileptic seizures Each hemisphere is divided into four lobes. “My emotions are in LIMBO” Hippos have great memory “Don’t ever make AMY mad” The “secretary” of the brain- sends information to proper place. Very similar to a CPU unit of a computer- the processor Like a cord that connects two computers Association areas are present on all 4 lobes and are responsible for higher mental functions such as learning, speaking, remembering, and thinking Frontal lobes- largest lobe- involved in planning, People will often hit themselves in the front of the thinking, emotional control, and muscle movement head and say, “I am so stupid”- makes sense- it is the thinking portion of the brain. The right hemisphere controls the left side of the body and the left hemisphere Motor cortexcontrols controls the right side of the body voluntary movements Parietal lobes- located top of the hear- processes In duck-duck-goose people “pat” others on the top of body information- touch the head Occipital lobes- located back of the headThink about the eye store, D.O.C. cipitial, or processes visual information remember, “O-h, I C (see) Temporal lobes- processes auditory information You listen to the “tempo” or the beat Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only. Imaging the brain Spatial ability and Language Neuroscience and Behavior Lateralization- notion that each hemisphere is responsible for specific abilities and tasks Right hemisphere- Left hemisphere processes language which includes the Broca’s and Wernicke’s areas handles nonverbalBroca’s area- involved in spoken Think about “boco” in Spanish- means mouth, or spatial, musical, language “broken” speech and visualWernicke’s area- processes the ability to Think about Professor Wernicke- no one can recognition tasks understand language, communication understand him Aphasia- refers to the inability to It is possible for someone to not be able to speakspeak or understand Broca’s aphasia, but understand and vice versa. CAT Scan- X-ray photographs of the brain MRI- uses magnetic fields that produce computer images of the brain EEG- measures electrical activity of the brainPET scan- measures brain activity through injecting radioactive glucose often used to measure brain waves during sleep while the brain is performing functions Lesioning- involves destroying a piece or part of the brain Submitted by Mike McLane, Sterling Heights High School, Michigan: Permission to use for face-to-face instruction with students only.