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UNIT II: THE HUMAN BRAIN How many cells are in the human brain? • 1 trillion! • Two categories: – Glial Cells – Neurons 1/15 Glial Cells • Three Functions: – Provide scaffolding to support both developing and mature neurons. – Wrap around neurons to form insulation from electrical signals – Releasing chemicals that influence neuron growth • Make up 90% of cells in brain! 2/15 Neurons • 100 billion cells - both sends and receives messages and signals (up to 268 mph!) • Allows us to: – Receive sensory information – Control muscle movement – Regulate digestion – Release hormones – Complete mental processes (thinking, etc.) 3/15 Neurons (cont) • Each neuron has hundreds of connections – Approximately 100 trillion neural connections in the brain • Which is more: the world’s communications, or the brain’s? • 0.00005% 4/15 Neuron Growth • Humans born with all our neurons that slowly die over our lifetime. • What two areas of the brain does new research suggest can regrow? – Hippocampus and olfactory bulb • Humans do have the ability to rewire our brains -> recover from traumatic event 5/15 Alzheimer’s Disease • Excessive buildup of protein amyloid destroys neurons faster than body can repair them. • All people produce amyloid, Alzheimer’s patients cannot get rid of it – Teeth plaque • Only “cure” right now is to slow or stop amyloid buildup 6/15 Neurons – Structure and Function 1. Cell body – egg-shaped structure that provides fuel, manufactures chemicals, maintains working order in the neuron, contains neurons DNA 7/15 Neurons – Structure and Function 2. Dendrites – Branchlike extensions; receive signals from cells or other neurons and pass them to the cell body. 8/15 Neurons – Structure and Function 3. Axon – single threadlike structure, carries messages to other neurons, organs, or muscles. Can be the length of the width of a human hair, or over 3 feet! 9/15 Neurons – Structure and Function 4. Myelin Sheath – looks like separate tube-like segments composed of fatty tissue. Prevents interference from other electrical signals and helps signals travel faster. 10/15 Neurons – Structure and Function 5. Terminal bulbs – look like tiny bubbles at the end of axon’s branches. Acts like a tiny container that stores neurotransmitters. Do not actually touch any neighboring organs, muscles, or cells. 11/15 Neurons – Structure and Function 6. Synapse – Infinitely small gap between terminal bulb and its neighboring organ, muscle, or other neural cells. Terminal bulbs eject neurotransmitters into the synapse to send messages. 12/15 What’s Wrong Here? 13/15 Reattaching Limbs • Limbs can be reattached because of something we call nerves. • In whole body except brain/spinal cord • String-like bundles of axons and dendrites • Carry messages from senses, skin, muscles, and organs 14/15 Reattaching Limbs • Nerves (but not neurons) have the ability to regrow • Gives us the ability to reattach limbs • Difference between nerve and neuron: – Neuron is individual cell – Nerve is a group of neurons • Think of nerves as the superfast lane of highway neurons use to get signals to your brain 15/15