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Neuroscience and Consciousness Chapter 2 Neural Communication The body’s information system is built from billions of interconnected cells called neurons. 3 Main Types • Sensory-information to the brain • Motor- information from the brain • Interneurons- communication b/w neurons Neuron A nerve cell, or a neuron, consists of many different parts. Parts of a Neuron Cell Body: Life support center of the neuron. Dendrites: Branching extensions at the cell body. Receive messages from other neurons. Axon: Long single extension of a neuron, covered with myelin [MY-uh-lin] sheath to insulate and speed up messages through neurons. Terminal Branches of axon: Branched endings of an axon that transmit messages to other neurons. Action Potential A neural impulse. A brief electrical charge that travels down an axon and is generated by the movement of positively charged atoms in and out of channels in the axon’s membrane. Action Potential Properties All-or-None Response: A strong stimulus can trigger more neurons to fire, and to fire more often, but it does not affect the action potentials strength or speed. Intensity of an action potential remains the same throughout the length of the axon. Synapse Synapse [SIN-aps] a junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron. This tiny gap is called the synaptic gap or cleft. Neurotransmitters Neurotransmitters (chemicals) released from the sending neuron travel across the synapse and bind to receptor sites on the receiving neuron, thereby influencing it to generate an action potential. How Neurotransmitters Influence Us Serotonin pathways are involved with mood regulation. Linked to Depression From Mapping the Mind, Rita Carter, © 1989 University of California Press Dopamine Pathways Dopamine pathways are involved with diseases such as schizophrenia and Parkinson’s disease. Responsible for motivation, interest, and drive From Mapping the Mind, Rita Carter, © 1989 University of California Press Norepinephrine • Helps control alertness and arousal • It regulates attention, mental focus, arousal, and cognition • High levels have been linked to sleep problems, anxiety and ADHD Neurotransmitters Nervous System Central Nervous System (CNS) Peripheral Nervous System (PNS) The Nervous System Nervous System: Consists of all the nerve cells. It is the body’s speedy, electrochemical communication system. Central Nervous System (CNS): the brain and spinal cord. Peripheral Nervous System (PNS): the sensory and motor neurons that connect the central nervous system (CNS) to the rest of the body. Kinds of Neurons Sensory Neurons carry incoming information from the sense receptors to the CNS. Motor Neurons carry outgoing information from the CNS to muscles and glands. Interneurons connect the two neurons. Motor Neuron (Multipolar) Peripheral Nervous System Somatic Nervous System: The division of the peripheral nervous system that controls the body’s skeletal muscles. Autonomic Nervous System: Part of the PNS that controls the glands, organs, and other muscles. The Nerves Nerves consist of neural “cables” containing many axons. They are part of the peripheral nervous system and connect muscles, glands, and sense organs to the central nervous system. Autonomic Nervous System (ANS) Sympathetic Nervous System: Division of the ANS that arouses the body, mobilizing its energy in stressful situations. Parasympathetic Nervous System: Division of the ANS that calms the body, conserving its energy. Autonomic Nervous System (ANS) Sympathetic NS “Arouses” (fight-or-flight) Parasympathetic NS “Calms” (rest and digest) The Nervous System The Endocrine System The Endocrine System is the body’s “slow” chemical communication system. Communication is carried out by hormones synthesized by a set of glands. Hormones Hormones are chemicals synthesized by the endocrine glands that are secreted in the bloodstream. Hormones affect the brain and many other tissues of the body. For example, epinephrine (adrenaline) increases heart rate, blood pressure, blood sugar, and feelings of excitement during emergency situations. Pituitary Gland Is called the “master gland.” The anterior pituitary lobe releases hormones that regulate other glands. Plays a role in growth. Brainstem The Medulla [muhDUL-uh] is the base of the brainstem that controls heartbeat and breathing. Brainstem The Thalamus [THALuh-muss] is the brain’s sensory switchboard, located on top of the brainstem. It directs messages to the sensory areas in the cortex and transmits replies to the cerebellum and medulla. Brainstem Reticular Formation is a nerve network in the brainstem that plays an important role in controlling arousal. -keeps us alert, even while sleeping Cerebellum The “little brain” attached to the rear of the brainstem. It helps coordinate voluntary movements and balance. Processes and stores memory we cannot consciously recall (muscle memory). The Limbic System The Limbic System is a doughnut-shaped system of neural structures at the border of the brainstem and cerebrum, associated with emotions such as fear, aggression and drives for food and sex. It includes the hippocampus, amygdala, and hypothalamus. Amygdala The Amygdala [ah-MIGdah-la] consists of two lima bean-sized neural clusters linked to the emotions of fear and anger. Hypothalamus The Hypothalamus lies below (hypo) the thalamus. It directs several maintenance activities like eating, drinking, body temperature, and control of emotions. It helps govern the endocrine system via the pituitary gland. The Cerebral Cortex The intricate fabric of interconnected neural cells that covers the cerebral hemispheres. It is the body’s ultimate control and information processing center. Structure of the Cortex Each brain hemisphere is divided into four lobes that are separated by prominent fissures. These lobes are the frontal lobe (forehead), parietal lobe (top to rear head), occipital lobe (back head) and temporal lobe (side of head). Phineas Gage? Pg.42-43 Functions of the Cortex The Motor Cortex is the area at the rear of the frontal lobes that control voluntary movements. The Sensory Cortex (parietal cortex) receives information from skin surface and sense organs. Visual Function The functional MRI scan shows the visual cortex is active as the subject looks at faces. Courtesy of V.P. Clark, K. Keill, J. Ma. Maisog, S. Courtney, L.G. Ungerleider, and J.V. Haxby, National Institute of Mental Health Auditory Function The functional MRI scan shows the auditory cortex is active in patients who hallucinate. Language Aphasia is an impairment of language, usually caused by left hemisphere damage either to Broca’s area (impaired speaking) or to Wernicke’s area (impaired understanding). The Brain’s Plasticity The brain is sculpted by our genes but also by our experiences. Plasticity refers to the brain’s ability to modify itself after some types of injury or illness. Right-Left Differences People show left-right hemispheric differences in mental abilities. A number of brain scan studies show normal individuals engage their right brain when completing a perceptual task and their left brain when carrying out a linguistic task. Right Brain vs. Left Brain Dominance • Left Brain- analytical, organized, would judge objects by their relationships • Right Brain-creative, free-thinking, would judge objects by their physical similarities Forms of Consciousness AP Photo/ Ricardo Mazalan Stuart Franklin/ Magnum Photos Christine Brune Bill Ling/ Digital Vision/ Getty Images Consciousness, modern psychologists believe, is an awareness of ourselves and our environment. Selective Attention Our conscious awareness processes only a small part of all that we experience. We intuitively make use of the information we are not consciously aware of. Inattentional Blindness Daniel Simons, University of Illinois Inattentional blindness refers to the inability to see an object or a person in our midst. Simons & Chabris (1999) showed that half of the observers failed to see the gorilla-suited assistant in a ball passing game. Change Blindness Change blindness is a form of inattentional blindness in which two-thirds of individuals giving directions failed to notice a change in the individual asking for directions. Change Blindness Another Example © 1998 Psychonomic Society Inc. Image provided courtesy of Daniel J. Simmons. Sleep & Dreams Sleep – the irresistible tempter to whom we inevitably succumb. Mysteries about sleep and dreams have just started unraveling in sleep laboratories around the world. Biological Rhythms and Sleep Illustration © Cynthia Turner 2003 Circadian Rhythms occur on a 24-hour cycle and include sleep and wakefulness. Termed our “biological clock,” it can be altered by artificial light. Light triggers the nucleus to decrease (morning) melatonin from the pineal gland and increase (evening) it at nightfall. Sleep Stages Measuring sleep: About every 90 minutes, we pass through a cycle of five distinct sleep stages. Hank Morgan/ Rainbow Awake but Relaxed When an individual closes his eyes but remains awake, his brain activity slows down to a large amplitude and slow, regular alpha waves (9-14 cps). A meditating person exhibits an alpha brain activity. Sleep Stages 1-2 During early, light sleep (stages 1-2) the brain enters a high-amplitude, slow, regular wave form called theta waves. A person who is daydreaming shows theta activity. (Hallucinations) Theta Waves Sleep Stages 3-4 During deepest sleep (stages 3-4), brain activity slows down. There are large-amplitude, slow delta waves. Stage 5: REM Sleep After reaching the deepest sleep stage (4), the sleep cycle starts moving backward towards stage 1. Although still asleep, the brain engages in lowamplitude, fast and regular beta waves much like awake-aroused state. A person during this sleep exhibits Rapid Eye Movements (REM) and reports vivid dreams if you awaken shortly after the dream. 90-Minute Cycles During Sleep With each 90-minute cycle, stage 4 sleep decreases and the duration of REM sleep increases. (usually about 4-6 periods of REM each night) Why do we sleep? We spend one-third of our lives sleeping. Jose Luis Pelaez, Inc./ Corbis If an individual remains awake for several days, immune function and concentration deteriorates and the risk of accidents increases. Teenage Sleep • Sleep less than 7 hours a night • Why does this happen? – Industrialized Countries? Sleep Deprivation 1. Fatigue and subsequent death. 2. Impaired concentration and performance. 3. Emotional irritability. 4. Depressed immune system. • Inability to fight off disease 5. Greater vulnerability. 6. Alters metabolism and hormonal functions 7. Jet Lag- consequence of travel 8. We sleep less today because there are more distractions Accidents Frequency of accidents increase with loss of sleep Sleep Theories 1. Sleep Protects: Sleeping in the darkness when predators loomed about kept our ancestors out of harm’s way. 2. Sleep Helps us Recover: Sleep helps restore and repair brain tissue. Helps maintain mood and emotion 3. Sleep Helps us Remember: Sleep restores and rebuilds our fading memories. 4. Sleep may play a role in the growth process: During sleep, the pituitary gland releases growth hormone. Older people release less of this hormone and sleep less. Sleep Disorders 1. Insomnia: A persistent inability to fall asleep, stay asleep, wakes early 2. Narcolepsy: Overpowering urge to fall asleep that may occur while talking or standing up. 3. Sleep apnea: Failure to breathe when asleep. – – Snoring- narrowing of the nasal passage Sleep Apnea video Sleep Disorders Children are most prone to: Night terrors: The sudden arousal from sleep with intense fear accompanied by physiological reactions (e.g., rapid heart rate, perspiration) which occur during Stage 4 sleep. Sleepwalking (somnambulism): A Stage 4 disorder which is usually harmless and unrecalled the next day. Sleeptalking (somniloquy): A condition that runs in families, like sleepwalking. Sleep Disorders Video Night Terror Example Dreams The link between REM sleep and dreaming has opened up a new era of dream research. EEG (electroencephalogram) allows us to study sleep What We Dream Manifest Content: A Freudian term meaning the story line of dreams (what we most remember). 1. Negative Emotional Content: 8 out of 10 dreams have negative emotional content. 2. Failure Dreams: People commonly dream about failure, being attacked, pursued, rejected, or struck with misfortune. 3. Sexual Dreams: Contrary to our thinking, sexual dreams are sparse. Sexual dreams in men are 1 in 10; and in women 1 in 30. Why We Dream- video 1. Wish Fulfillment: Sigmund Freud suggested that dreams provide a psychic safety valve to discharge unacceptable feelings. The dream’s manifest (apparent) content may also have symbolic meanings (latent content) that signify our unacceptable feelings. 2. Information Processing: Dreams may help sift, sort, and fix a day’s experiences in our memories. Why We Dream 3. Physiological Function: Dreams provide the sleeping brain with periodic stimulation to develop and preserve neural pathways. Neural networks of newborns are quickly developing; therefore, they need more sleep. Why We Dream 4. Activation-Synthesis Theory: Suggests that the brain engages in a lot of random neural activity. Dreams make sense of this activity. 5. Cognitive Development: Some researchers argue that we dream as a part of brain maturation and cognitive development. All dream researchers believe we need REM sleep. When deprived of REM sleep and then allowed to sleep, we show increased REM sleep called REM Rebound. Dream Theories Summary • Why do we dream? Nova 58 mins