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Neurons and the Nervous System Nervous System – Central nervous system (CNS): • Brain • Spinal cord – Peripheral nervous system (PNS): • Sensory neurons • Motor neurons (somatic and autonomic) Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. The Nervous System The Nervous System Central Nervous System (CNS) Brain Peripheral Nervous System (PNS) Spinal Cord • Motor Neurons Somatic Nervous System voluntary movements via skeletal muscles Sympathetic - “Fight-or-Flight” responses • Sensory Neurons Autonomic Nervous System organs, smooth muscles Parasympathetic - maintenance Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Divisions of the autonomic nervous system The Nervous System • A physical organ system like any other • The main cell of the nervous system are: –Neurons The Neuron • The basic functional unit of the nervous system. • Function: Send impulses to and from the CNS and PNS Neuron Structure • Dendrite Fine hair-like extensions on the end of a neuron. –Function: receive incoming stimuli. • Cell Body or Soma The control center of the neuron. –Function: Directs impulses from the dendrites to the axon. • Nucleus Control center of the Soma. –Function: Tells the soma what to do. • Axon Pathway for the nerve impulse (electrical message) from the soma to the opposite end of the neuron. • Myelin Sheath An insulating layer around an axon. Made up of Schwann cells. • Nodes of Ranvier Gaps between schwann cells. – Conduction of the impulse. (Situation where speed of an impulse is greatly increased by the message ‘jumping’ the gaps in an axon). Types of Neurons • There are 3 types of neurons. 1. Sensory Neurons Neurons located near receptor organs (skin, eyes, ears). Function: receive incoming stimuli from the environment. 2. Motor Neurons Neurons located near effectors (muscles and glands) Function: Carry impules to effectors to initiate a response. 3. Interneurons Neurons that relay messages between other neurons such as sensory and motor neurons. (found most often in Brain and Spinal chord). Types of Neurons Nerves • Nerves Collections of neurons that are joined together by connective tissue. • Responsible for transferring impulses from receptors to CNS and back to effectors. Three main types of neurons • Sensory Neurons • Interneurons • Motor Neurons Sensory vs. Motor sensory nerve e.g., skin Neurons that send signals from the senses, skin, muscles, and internal organs to the CNS motor nerve Neurons that transmit commands from the CNS to the muscles, glands, and organs Gray’s Anatomy 38 1999 e.g., muscle The Withdrawal Reflex Neuron Anatomy and Neural Communication Neurons Dendrites Cell Body Myelin Sheath Axon of another neuron Axon Dendrites of another neuron Neural Anatomy Dendrite the bushy, branching extensions of a neuron that receive messages and conduct impulses toward the cell body Axon the extension of a neuron, ending in branching terminal fibers, through which messages are sent to other neurons or to muscles or glands Neural Anatomy and communication Synapse junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron tiny gap at this junction is called the synaptic gap or cleft Synapse movie Specific Parts: The Neuron Structure Specific Parts: The Neuron Function 1. 3. 2. Neurons = 3 functions: Reception, Conduction, Transmission Communication • Impulse releases neurotransmitter from vesicles • Neurotransmitter enters synaptic gap • Neurotransmitter binds to receptors on the receiving neuron Myelin Sheath – Fatty material made by glial cells – Insulates the axon – Allows for rapid movement of electrical impulses along axon – Nodes of Ranvier: gaps in myelin sheath where action potentials are transmitted – Multiple sclerosis is a breakdown of myelin sheath – Speed of neural impulse Ranges from 2 – 200+ mph Myelinization clip Myelin conduction clip Neurotransmitters chemical messengers that travel across the synaptic gaps between neurons when released by the sending neuron, neurotransmitters travel across the synapse and bind to receptor sites on the receiving neuron, thereby influencing whether it will generate a neural impulse