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Question: What Is a Neuron? Answer: A neuron is a nerve cell that is the basic building block of the nervous system. Neurons are similar to other cells in the human body in a number of ways, but there is one key difference between neurons and other cells. Neurons are specialized to transmit information throughout the body. These highly specialized nerve cells are responsible for communicating information in both chemical and electrical forms. There are also several different types of neurons responsible for different tasks in the human body. Sensory neurons carry information from the sensory receptor cells throughout the body to the brain. Motor neurons transmit information from the brain to the muscles of the body. Interneurons are responsible for communicating information between different neurons in the body. Neurons vs. Other Cells Similarities with other cells: Neurons and other body cells both contain a nucleus that holds genetic information. Neurons and other body cells are surrounded by a membrane that protects the cell. The cell bodies of both cell types contain organelles that support the life of the cell, including mitochondria, Golgi bodies, and cytoplasm. Differences that make neurons unique: Unlike other body cells, neurons stop reproducing shortly after birth. Because of this, some parts of the brain have more neurons at birth than later in life because neurons die but are not replaced. While neurons do not reproduce, research has shown that new connections between neurons form throughout life. Neurons have a membrane that is designed to sends information to other cells. The axon and dendrites are specialized structures designed to transmit and receive information. The connections between cells are known as a synapses. Neurons release chemicals known as The Structure of a Neuron There are three basic parts of a neuron: the dendrites, the cell body and the axon. However, all neurons vary somewhat in size, shape, and characteristics depending on the function and role of the neuron. Some neurons have few dendritic branches, while others are highly branched in order to receive a great deal of information. Some neurons have short axons, while others can be quite long. The longest axon in the human body extends from the bottom of the spine to the big toe and averages a length of approximately three feet! Learn more about the structure of a neuron. Neurotransmitters Neurotransmitters are an essential part of our everyday functioning. While it is not known exactly how many neurotransmitters exist, scientists have identified more than 100 of these chemical messengers. What effects do each of these neurotransmitters have on the body? What happens when disease or drugs interfere with these chemical messengers? The following are just a few of the major neurotransmitters, their known effects, and disorders they are associated with. Acetylcholine: Associated with memory, muscle contractions, and learning. A lack of acetylcholine in the brain is associated with Alzheimer’s disease. Endorphins: Associated with emotions and pain perception. The body releases endorphins in response to fear or trauma. These chemical messengers are similar to opiate drugs such as morphine, but are significantly stronger. Dopamine: Associated with thought and pleasurable feelings. Parkinson’s disease is one illness associated with deficits in dopamine, while schizophrenia is strongly linked to excessive amounts of this chemical messenger. Communication Between Synapses Once an electrical impulse has reached the end of an axon, the information must be transmitted across the synaptic gap to the dendrites of the adjoining neuron. In some cases, the electrical signal can almost instantaneously bridge the gap between the neurons and continue along its path. In other cases, neurotransmitters are needed to send the information from one neuron to the next. Neurotransmitters are chemical messengers that are released from the axon terminals to cross the synaptic gap and reach the receptor sites of other neurons. In a process known as reuptake, these neurotransmitters attach to the receptor site and are reabsorbed by the neuron to be reused. Dendrites serve as the input region of the neuron and receive information from other cells. Image: Kendra Cherry Dendrites are treelike extensions at the beginning of a neuron that help increase the surface area of the cell body. These tiny protrusions receive information from other neurons and transmit electrical stimulation to the soma. Dendrites are also covered with synapses. Dendrite Characteristics Most neurons have many dendrites However, some neurons may have only one dendrite Short and highly branched Transmits information to the cell body The soma is where the signals from the dendrites are joined and passed on. The soma and the nucleus do not play an active role in the transmission of the neural signal. Instead, these two structures serve to maintain the cell and keep the neuron functional. The support structures of the cell include mitochondria, which provide energy for the cell, and the Golgi apparatus, which packages products created by the cell and secretes them outside the cell wall. Axon Hillock Image: Kendra Cherry The axon hillock is located at the end of the soma and controls the firing of the neuron. If the total strength of the signal exceeds the threshold limit of the axon hillock, the structure will fire a signal (known as an action potential) down the axon. Image: Kendra Cherry The axon is the elongated fiber that extends from the cell body to the terminal endings and transmits the neural signal. The larger the axon, the faster it transmits information. Some axons are covered with a fatty substance called myelin that acts as an insulator. These myelinated axons transmit information much faster than other neurons. Axon Characteristics Most neurons have only one axon Transmit information away from the cell body May or may not have a myelin covering The terminal buttons are located at the end of the neuron and are responsible for sending the signal on to other neurons. At the end of the terminal button is a gap known as a synapse. Neurotransmitters are used to carry the signal across the synapse to other neurons.