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Biology and Behavior Chapter 3 1 Neural Communication The body’s information system is built from billions of interconnected cells called neurons. 2 Neuron A nerve cell, or a neuron, consists of many different parts. 3 Parts of a Neuron Cell Body: Life support center of the neuron. Dendrites: Branching extensions at the cell body. Receive messages from other neurons. Axon: Long single extension of a neuron, covered with myelin sheath to insulate and speed up messages through neurons. Axon: Terminals: Branched endings of an axon that transmit messages to other neurons. Synapse: Space between the neurons 4 How does a Neuron fire? • Resting Potential: slightly negative charge. • Reach the threshold when enough neurotransmitters reach dendrites. • Go into Action Potential. • All-or-none response. • Transfer of ions across axon’s membrane causes electrical charge. It is an electrochemical process • Electrical inside the neuron • Chemical outside the neuron (in the synapse in the form of a neurotransmitter). • The firing is call Action Potential. 6 The All-or None Response • The idea that either the neuron fires or it does not- no part way firing. • Like a gun 7 Steps of Action Potential • Dendrites receive neurotransmitter from another neuron across the synapse. • Reached its threshold- then fires based on the all-or-none response. • Opens up a portal in axon, and lets in positive ions (Sodium) which mix with negative ions (Potassium) that is already inside the axon (thus Neurons at rest have a slightly negative charge). • The mixing of + and – ions causes an electrical charge that opens up the next portal (letting in more K) while closing the original portal. • Process continues down axon to the axon terminal. • Terminal buttons turns electrical charge into chemical (neurotransmitter) and shoots message to next neuron across the synapse. 8 Refractory Period & Pumps Refractory Period: After a neuron fires an action potential it pauses for a short period to recharge itself to fire again. Sodium-Potassium Pumps: Sodium-potassium pumps pump positive ions out from the inside of the neuron, making them ready for another action potential. 9 Action Potential Properties All-or-None Response: When the depolarizing current exceeds the threshold, a neuron will fire. If the depolarizing current fails to exceed the threshold, a neuron will not fire. Intensity of an action potential remains the same throughout the length of the axon. 10 Synapse Synapse [SIN-aps] a junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron. This tiny gap is called the synaptic gap or cleft. 11 How Neurons Communicate 12 Neurotransmitters Neurotransmitters (chemicals) released from the sending neuron travel across the synapse and bind to receptor sites on the receiving neuron, thereby influencing it to generate an action potential. 13 TYPES OF NEUROTRANSMITTERS Acetylcholine (ACH) • Deals with motor movement and memory. • Lack of ACH has been linked to Alzheimer’s disease and muscle paralysis Dopamine • Deals with attention, motor movement and alertness. • Lack of dopamine has been linked to Parkinson’s disease. • Too much has been linked to schizophrenia. Serotonin • Involved in mood control. • Lack of serotonin has been linked to clinical depression. Endorphins • Involved in pain control. Divisions of the Nervous System 19 The Nervous System Nervous System: Consists of all the nerve cells. It is the body’s speedy, electrochemical communication system. Central Nervous System (CNS): the brain and spinal cord. Peripheral Nervous System (PNS): the sensory and motor neurons that connect the central nervous system (CNS) to the rest of the body. 20 Peripheral Nervous System • All nerves that are not encased in bone. • Everything but the brain and spinal cord. • Is divided into two categories….somatic and autonomic. Somatic Nervous System • Controls voluntary muscle movement. Autonomic Nervous System • Controls the automatic functions of the body. • Divided into two categories…the sympathetic and the parasympathetic Autonomic Nervous System (ANS) Sympathetic Nervous System: Division of the ANS that arouses the body, mobilizing its energy in stressful situations. Parasympathetic Nervous System: Division of the ANS that calms the body, conserving its energy. 24 Sympathetic Nervous System • Fight or Flight Response. • Automatically accelerates heart rate, breathing, dilates pupils, slows down digestion. Parasympathetic Nervous System • Automatically slows the body down after a stressful event. • Heart rate and breathing slow down, pupils constrict and digestion speeds up. 27 The Brain Brain Structures • Some scientists divide the brain up into three parts. • Hindbrain • Midbrain • Forebrain Hindbrain • Structures on top of our spinal cord. • Controls basic biological structures. The brain in purple makes up the hindbrain. 30 Medulla Oblongata • Located just above the spinal cord. Involved in control of • blood pressure • heart rate • breathing. 31 Pons • Located just above the medulla. • Connects hindbrain with midbrain and forebrain. • Involved in facial expressions, sleep, and attention 32 Cerebellum • Located in the back of our head- means little brain. • Coordinates muscle movements. Midbrain • Coordinates simple movements with sensory information. • Contains the reticular activating system: arousal and ability to focus attention. • If damaged…Coma Forebrain • Thalamus • Receives sensory information and sends them to appropriate areas of forebrain. • Like a switchboard. • Everything but smell. Hypothalamus The Hypothalamus lies below (hypo) the thalamus. It directs several maintenance activities like eating, drinking, body temperature, and control of emotions. It helps govern the endocrine system via the pituitary gland. 36 Hypothalamus • Maybe most important structure in the brain. Controls and regulates • Body temperature • Sexual Arousal • Hunger The most powerful • Thirst structure in the brain. • Endocrine System 37 Limbic System • EMOTIONAL CONTROL CENTER of the brain. • Made up of Hypothalamus, Amygdala and Hippocampus. The Limbic System The Limbic System is a doughnut-shaped system of neural structures at the border of the brainstem and cerebrum, associated with emotions such as fear, aggression and drives for food and sex. It includes the hippocampus, amygdala, and hypothalamus. 39 The Limbic System 40 Amygdala • Involved in how we process memory. • More involved in volatile emotions like fear & anger. 41 Hippocampus • Involved in the processing and storage of memories. 42 Cerebrum • Largest part of the brain • Surface of brain called the: cerebral cortex 43 Areas of the Cerebral Cortex • Divided into 4 lobes – – – – Frontal Temporal Parietal Occipital Frontal Lobes • Deals with planning, maintaining emotional control and abstract thought. • Contains Motor Cortex: sends signals to our body controlling muscle movements. • Contains Broca’s Area: responsible for controlling muscles that produce speech. • Damage to Broca’s Area is called Broca’s Aphasia: unable to make movements to talk. Contains Broca’s Area. 45 Motor and Sensory Cortexes 46 Parietal Lobes • Located at the top of our head. • Contains the somatosensory cortex. • Rest are association areas. Temporal Lobes • Process sound sensed by ears. • Not lateralized. • Contains Wernicke’s area which interprets written and spoken speech. • Wernike's Aphasia: unable to understand language: the syntax and grammar Occipital Lobes • In the back of our head. • Handles visual input from eyes. • Right half of each retina goes to left occipital lobe and vice versa. • Contains Visual Cortex: interprets messages from our eyes into images we can understand. The Corpus Callosum Divides the 2 hemispheres. 50 Hemispheres Divided into to hemispheres. • Contralateral control: right controls left and vice versa. In general, Left Hemisphere: logic and sequential tasks. Right Hemisphere: spatial and creative 51 tasks. Hemispheres • Divided into a left and right hemisphere. • Contralateral controlled- left controls right side of body and vice versa. • Brain Lateralization. • Lefties are better at spatial and creative tasks. • Righties are better at logic. Accidents Phineas Gage Story • Personality changed after the accident. 53 Brain Plasticity • The idea that the brain, when damaged, will attempt to find news ways to reroute messages. • Children’s brains are more plastic than adults. 54 Lesions Brain tumors also lesion brain tissue. Ways to study the Brain • Electroencephalogram (EEG) • Computerized Axial Tomography (CAT) • Magnetic Resonance Imaging (MRI) • Positron Emission Tomography (PET) • Functional MRI (fMRI) Electroencephalogram • Detects brain waves through their electrical output. • Used mainly in sleep research. 57 PET Scan Courtesy of National Brookhaven National Laboratories PET (positron emission tomography) Scan is a visual display of brain activity that detects a radioactive form of glucose while the brain performs a given task. 58 Positron Emission Tomography • Measures how much glucose the brain uses. 59 MRI Scan MRI (magnetic resonance imaging) uses magnetic fields and radio waves to produce computergenerated images that distinguish among different types of brain tissue. 60 Magnetic Resonance Imaging • More detailed picture of brain using magnetic field to knock electrons off axis. • Takes many still pictures and turns images into a movie like production. 61 Computerized Axial Tomography • function3D XRay of the brain. • Good for tumor locating 62 Functional MRI Shows the tissue and the function of the brain 63 The Endocrine System A system of glands that secrete hormones. Similar to nervous system, except hormones work a lot slower than neurotransmitters. Hormones Neurotransmitters 64 The Endocrine System The Endocrine System is the body’s “slow” chemical communication system. Communication is carried out by hormones synthesized by a set of glands. 65 Hormones Hormones are chemicals synthesized by the endocrine glands that are secreted in the bloodstream. Hormones affect the brain and many other tissues of the body. For example, epinephrine (adrenaline) increases heart rate, blood pressure, blood sugar and feelings of excitement during emergency situations. 66 The Major Endocrine Glands 67 Pituitary Gland Is called the “master gland.” The anterior pituitary lobe releases hormones that regulate other glands. The posterior lobe regulates water and salt balance. 68 Thyroid & Parathyroid Glands Regulate metabolic and calcium rate. 69 Adrenal Glands Adrenal glands consist of the adrenal medulla and the cortex. The medulla secretes hormones (epinephrine and norepinephrine) during stressful and emotional situations, while the adrenal cortex regulates salt and carbohydrate metabolism. 70 Gonads Sex glands are located in different places in men and women. They regulate bodily development and maintain reproductive organs in adults. 71