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... Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disease characterized by symptoms of inattention, hyperactivity and impulsivity. Converging data from different studies point to ADHD abnormalities in fronto-striatal circuits. Structural neuroimaging studies partially support f ...
... Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disease characterized by symptoms of inattention, hyperactivity and impulsivity. Converging data from different studies point to ADHD abnormalities in fronto-striatal circuits. Structural neuroimaging studies partially support f ...
neuropathology of dopamine systems in schizophrenia
... basal activity at time of death, while changes in subunit protein expression are related to long-term regulation of the enzyme, affecting the “reserve capacity” of the mitochondria to respond to higher energy demands. Finally, we performed neuronal counts of dopaminergic and total number of neurons ...
... basal activity at time of death, while changes in subunit protein expression are related to long-term regulation of the enzyme, affecting the “reserve capacity” of the mitochondria to respond to higher energy demands. Finally, we performed neuronal counts of dopaminergic and total number of neurons ...
The Anatomy of the Posterior Commissure
... colliculus and to continue directly to the medial longitudinal fasciculus. Fibers from the thalamic, pretectal, tectal region, fibers from the superior colliculus and the habenular nuclei are known to connect with the posterior commissure, but they have not been shown anatomically (3-5,12). Although ...
... colliculus and to continue directly to the medial longitudinal fasciculus. Fibers from the thalamic, pretectal, tectal region, fibers from the superior colliculus and the habenular nuclei are known to connect with the posterior commissure, but they have not been shown anatomically (3-5,12). Although ...
stimulant treatment history predicts frontal-striatal
... stimulation of postsynaptic monoamine receptors (e.g. Arnsten, 2006; Kuczenski & Segal, 1997; Volkow et al., 2001). Magnetic resonance imaging (MRI) techniques offer non-‐invasive, accessible, and versatile tools to study stimulant effects in the ...
... stimulation of postsynaptic monoamine receptors (e.g. Arnsten, 2006; Kuczenski & Segal, 1997; Volkow et al., 2001). Magnetic resonance imaging (MRI) techniques offer non-‐invasive, accessible, and versatile tools to study stimulant effects in the ...
A review of MRI findings in schizophrenia
... setting the stage for the development of the symptoms of schizophrenia. Or there may be additional factors, such as stress or neurotoxicity, that occur during adolescence or early adulthood and are necessary for the development of schizophrenia, and may be associated with neurodegenerative changes. ...
... setting the stage for the development of the symptoms of schizophrenia. Or there may be additional factors, such as stress or neurotoxicity, that occur during adolescence or early adulthood and are necessary for the development of schizophrenia, and may be associated with neurodegenerative changes. ...
Document
... brain and peripheral tissue as ubiquitous and tissue-specific alternatively spliced isoforms that regulate membrane dynamics and endocytosis in multiple cell types. The function of BIN1 in the brain and the mechanism(s) by which AD-associated BIN1 alleles increase the risk for the disease are not kn ...
... brain and peripheral tissue as ubiquitous and tissue-specific alternatively spliced isoforms that regulate membrane dynamics and endocytosis in multiple cell types. The function of BIN1 in the brain and the mechanism(s) by which AD-associated BIN1 alleles increase the risk for the disease are not kn ...
Martin, Neuroscientist 2005
... Box 1: Organization of the Mature Corticospinal System The corticospinal system connects the frontal and anterior parietal lobes with the spinal gray matter. Early in development, corticospinal neurons are distributed throughout much of the frontal and parietal lobes, and parts of the occipital and ...
... Box 1: Organization of the Mature Corticospinal System The corticospinal system connects the frontal and anterior parietal lobes with the spinal gray matter. Early in development, corticospinal neurons are distributed throughout much of the frontal and parietal lobes, and parts of the occipital and ...
JAMA SIDS
... [1.25] fmol/mg, respectively; P=.001). Male SIDS cases had significantly lower 5-HT1A binding density in the raphé obscurus compared with female cases (mean [SD], 16.2 [2.0] vs 29.6 [16.5] fmol/mg, respectively; P=.04) or with male and female controls combined (mean [SD], 53.9 [19.8] fmol/mg; P=.00 ...
... [1.25] fmol/mg, respectively; P=.001). Male SIDS cases had significantly lower 5-HT1A binding density in the raphé obscurus compared with female cases (mean [SD], 16.2 [2.0] vs 29.6 [16.5] fmol/mg, respectively; P=.04) or with male and female controls combined (mean [SD], 53.9 [19.8] fmol/mg; P=.00 ...
GnRH Protein Levels in Atrazine-Treated Axolotls
... months of age was chosen as the starting point for this study because we wanted to begin atrazine exposure during development, while GnRH-producing neurons were being formed. The control group was raised in 40% Holtfreter’s solution, a slightly saline solution that is the standard bowl water for axo ...
... months of age was chosen as the starting point for this study because we wanted to begin atrazine exposure during development, while GnRH-producing neurons were being formed. The control group was raised in 40% Holtfreter’s solution, a slightly saline solution that is the standard bowl water for axo ...
Acute and chronic effects of cannabinoids on human brain: gene-environment interactions
... Acute and chronic effects of cannabinoids on human brain: gene-environment interactions related to psychiatric disorders Albert Batalla Cases ...
... Acute and chronic effects of cannabinoids on human brain: gene-environment interactions related to psychiatric disorders Albert Batalla Cases ...
Effects of Fructose vs Glucose on Regional
... flow (CBF) after glucose or fructose ingestion. Secondary outcomes included wholebrain analyses to explore regional CBF changes, functional connectivity analysis to investigate correlations between the hypothalamus and other brain region responses, and hormone responses to fructose and glucose inges ...
... flow (CBF) after glucose or fructose ingestion. Secondary outcomes included wholebrain analyses to explore regional CBF changes, functional connectivity analysis to investigate correlations between the hypothalamus and other brain region responses, and hormone responses to fructose and glucose inges ...
Gender Training for Security Sector Personnel – good practices and lessons learned
... According to a survey by the United States (US) Department of Defence, the reported rate of sexual harassment of active-duty members declined between 1995 and 2002 for both women (46% vs. 24%) and men (8% vs. 3%).6 Around 75% of the personnel had received sexual harassment training and more than 80% ...
... According to a survey by the United States (US) Department of Defence, the reported rate of sexual harassment of active-duty members declined between 1995 and 2002 for both women (46% vs. 24%) and men (8% vs. 3%).6 Around 75% of the personnel had received sexual harassment training and more than 80% ...
Molecular and Cellular Endocrinology Metabolic control of puberty
... that leptin acts (mainly) indirectly in the control of the GnRH system. Yet, there has been a conspicuous lack of functional data for such an indirect mode of action until very recently. In the last months, however, Quennell et al. (2009) have presented conclusive experimental evidence to demonstrat ...
... that leptin acts (mainly) indirectly in the control of the GnRH system. Yet, there has been a conspicuous lack of functional data for such an indirect mode of action until very recently. In the last months, however, Quennell et al. (2009) have presented conclusive experimental evidence to demonstrat ...
INDUCTION AND RECOVERY TIME COURSE OF RAT BRAIN
... aliquots at ⫺80°C until used. Microsomes from rat liver were prepared as described previously (Howard et al., 2001). The protein content of each sample was assayed using a Bio-Rad protein assay kit. Western Blotting. Membrane proteins were separated by SDS-polyacrylamide gel electrophoresis (4% stac ...
... aliquots at ⫺80°C until used. Microsomes from rat liver were prepared as described previously (Howard et al., 2001). The protein content of each sample was assayed using a Bio-Rad protein assay kit. Western Blotting. Membrane proteins were separated by SDS-polyacrylamide gel electrophoresis (4% stac ...
Leptin: A metabolic signal affecting central regulation of
... be linked to onset of puberty and weaning-to-estrus interval in the pig. Adipose tissue is no longer considered as only a depot to store excess energy in the form of fat. Recent findings demonstrate that numerous genes, i.e., relaxin, interleukins and other cytokines and biologically active substanc ...
... be linked to onset of puberty and weaning-to-estrus interval in the pig. Adipose tissue is no longer considered as only a depot to store excess energy in the form of fat. Recent findings demonstrate that numerous genes, i.e., relaxin, interleukins and other cytokines and biologically active substanc ...
Wager, T. D., Kang, J., Johnson, T. D., Nichols, T. E., Satpute, A. B.
... vs. [25]), making it difficult to identify generalizable models of specific emtion types. The study presented here directly addresses both these issues. In this paper, our goal was to develop a generative, brain-based model of the five most common emotion categories—fear, anger, disgust, sadness, an ...
... vs. [25]), making it difficult to identify generalizable models of specific emtion types. The study presented here directly addresses both these issues. In this paper, our goal was to develop a generative, brain-based model of the five most common emotion categories—fear, anger, disgust, sadness, an ...
Goodwin S.F., Taylor, B.J., Villella, A., Foss, M., Ryner, L. C., Baker, B. S., and Hall, J. C.
... splice acceptor sites that create alternative processing pathways. In situ hybridization revealed no alterations in the locations of cells expressing the P1-fru-promoter-derived transcripts in fru2, fru3, fru4, and frusat pharate adults. For the fru1 mutant (which is due to an inversion breakpoint n ...
... splice acceptor sites that create alternative processing pathways. In situ hybridization revealed no alterations in the locations of cells expressing the P1-fru-promoter-derived transcripts in fru2, fru3, fru4, and frusat pharate adults. For the fru1 mutant (which is due to an inversion breakpoint n ...
clinical dilemmas and surgical treatment of penoscrotal, scrotal and
... and D (HOXA and HOXD) genes in early genital tubercle outgrowth and patterning (). As discussed earlier, antiandrogen might plays a role in the development of hypospadias. It has been shown that pregnant female mice exposed to synthetic estrogen compounds ...
... and D (HOXA and HOXD) genes in early genital tubercle outgrowth and patterning (). As discussed earlier, antiandrogen might plays a role in the development of hypospadias. It has been shown that pregnant female mice exposed to synthetic estrogen compounds ...
Cortical Involvement During Sustained Lower Limb Contractions
... extremity and the influence of cortical inputs are poorly understood. The purpose of this dissertation was to investigate the role the cortex plays in modulating force control during static contractions with the lower limb and to determine the influence of manipulating cortical inputs. Aim 1 determi ...
... extremity and the influence of cortical inputs are poorly understood. The purpose of this dissertation was to investigate the role the cortex plays in modulating force control during static contractions with the lower limb and to determine the influence of manipulating cortical inputs. Aim 1 determi ...
The Role of Kisspeptin Signaling in Reproduction
... contrast, the ARC does not display sexually dimorphic differences in kisspeptin neuron density or distribution in rodents (44, 50). In sheep, however, the ARC is sexually dimorphic with half the number of kisspeptin neurons in rams compared with ewes (10). These sexually dimorphic kisspeptin neurons ...
... contrast, the ARC does not display sexually dimorphic differences in kisspeptin neuron density or distribution in rodents (44, 50). In sheep, however, the ARC is sexually dimorphic with half the number of kisspeptin neurons in rams compared with ewes (10). These sexually dimorphic kisspeptin neurons ...
Primary amenorrhea
... The menstrual cycle = a biological marker of general health in adolescents Menstrual irregularity / amenorrhea = common occurrence within the 2 years after menarche * Prolonged amenorrhea > 14 ...
... The menstrual cycle = a biological marker of general health in adolescents Menstrual irregularity / amenorrhea = common occurrence within the 2 years after menarche * Prolonged amenorrhea > 14 ...
Primary Structure and Function of Three Gonadotropin
... preparative chromatography. Fractions of 1 ml were collected from each chromatography step, and aliquots were assayed for immunoreactive GnRH (irGnRH). The absence of residual contaminating GnRH on the column was confirmed before purification of GnRH by collecting and assaying fractions of blank run ...
... preparative chromatography. Fractions of 1 ml were collected from each chromatography step, and aliquots were assayed for immunoreactive GnRH (irGnRH). The absence of residual contaminating GnRH on the column was confirmed before purification of GnRH by collecting and assaying fractions of blank run ...
From Lesions to Leptin: Review Hypothalamic Control of Food
... hormone is thought to be anorectic, it is likely that lateral hypothalamic area neurons are influenced by physiological stimuli to integrate body weight and food intake. It is not known whether the same lateral hypothalamic neurons can express corticotropin releasing hormone during dehydration and M ...
... hormone is thought to be anorectic, it is likely that lateral hypothalamic area neurons are influenced by physiological stimuli to integrate body weight and food intake. It is not known whether the same lateral hypothalamic neurons can express corticotropin releasing hormone during dehydration and M ...
Developmental structure in brain evolution
... not the only sort of specialization we could consider, however. Complicated behaviors might have complex and idiosyncratic internal circuitry, from elaborated specialized capacities to single percepts or actions. We have such examples as “the song system” as a coordinated perceptuomotor system; we s ...
... not the only sort of specialization we could consider, however. Complicated behaviors might have complex and idiosyncratic internal circuitry, from elaborated specialized capacities to single percepts or actions. We have such examples as “the song system” as a coordinated perceptuomotor system; we s ...