
A network of topographic numerosity maps in human
... not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
... not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
Emotional experiences of tension and suspense: psychological
... advice, and continuous support. I am also very grateful to Prof. Dr. Arthur Jacobs for his support and for accepting to be the second reviewer of this thesis. I also thank Prof. Dr. Winfried Menninghaus, Dr. Martin Rohrmeier, and Philipp Engel for their help and advice in the context of the “Aesthet ...
... advice, and continuous support. I am also very grateful to Prof. Dr. Arthur Jacobs for his support and for accepting to be the second reviewer of this thesis. I also thank Prof. Dr. Winfried Menninghaus, Dr. Martin Rohrmeier, and Philipp Engel for their help and advice in the context of the “Aesthet ...
Curriculum Vitae - Laureate Institute for Brain Research
... I am collaborating with several investigators at UCSD and other institutions to study the neural basis of psychiatric disorders. Specifically, I am working with Drs. Susan Tapert and Gerhard Schulteis on NIDA supported P-20 Center Grant to examine the role of interoception for drug addiction. Intero ...
... I am collaborating with several investigators at UCSD and other institutions to study the neural basis of psychiatric disorders. Specifically, I am working with Drs. Susan Tapert and Gerhard Schulteis on NIDA supported P-20 Center Grant to examine the role of interoception for drug addiction. Intero ...
By ON THE ROLE OF THE SUPERIOR COLLICULUS IN THE CONTROL... VISUALLY-GUIDED SACCADES
... of simulating saccadic sensory to motor transformations. This model was designed to predict how the spatial interactions between neural signals related to visual processing and saccadic preparation interact within the SC to influence saccadic reaction time. I concluded that saccade latency was stron ...
... of simulating saccadic sensory to motor transformations. This model was designed to predict how the spatial interactions between neural signals related to visual processing and saccadic preparation interact within the SC to influence saccadic reaction time. I concluded that saccade latency was stron ...
The Role of Temporal Structure in Human Vision
... another, nearby location. If the two events occur within 20 msec or so of one another, will they appear as a single event, namely, two stimuli occurring simultaneously at two locations? The answer is no—one readily experiences compelling apparent motion, with a unitary stimulus seen to move from the ...
... another, nearby location. If the two events occur within 20 msec or so of one another, will they appear as a single event, namely, two stimuli occurring simultaneously at two locations? The answer is no—one readily experiences compelling apparent motion, with a unitary stimulus seen to move from the ...
Longtin - noise in neural systems
... reflex (Chapter 9). Such methods are especially useful for stiff stochastic problems, such as the Hodgkin–Huxley or FitzHugh–Nagumo equations with stochastic forcing, where one usually uses an adaptive method in the noiseless case, but is confined to a fixed step method with noise. Stochastic simulation ...
... reflex (Chapter 9). Such methods are especially useful for stiff stochastic problems, such as the Hodgkin–Huxley or FitzHugh–Nagumo equations with stochastic forcing, where one usually uses an adaptive method in the noiseless case, but is confined to a fixed step method with noise. Stochastic simulation ...
frontal functions, connectivity and neural efficiency underpinning
... demonstrated between error detection processes and error evaluation processes and with the apparent inhibition or uncoupling of the latter, both of which are processes emanating from the anterior cingulate. These processes were measured with event-related potentials (ERPs) in a Stroop-like conflict ...
... demonstrated between error detection processes and error evaluation processes and with the apparent inhibition or uncoupling of the latter, both of which are processes emanating from the anterior cingulate. These processes were measured with event-related potentials (ERPs) in a Stroop-like conflict ...
1
... suggest an important role of the cerebellum. However, nearly all these studies are based on the analysis of apriori selected regions of interest (known as ROI approaches). Recent studies, using more global approaches, found that ADHD structural abnormalities were not limited to fronto-striatal-cereb ...
... suggest an important role of the cerebellum. However, nearly all these studies are based on the analysis of apriori selected regions of interest (known as ROI approaches). Recent studies, using more global approaches, found that ADHD structural abnormalities were not limited to fronto-striatal-cereb ...
... meet criteria for the disorder during their teenage years. Volumetric studies in children with Attention-Deficit/Hyperactivity Disorder (ADHD) have consistently found global reductions of total brain volume with frontalstriatal regions, cerebellum and parieto-temporal regions particularly affected r ...
Propofol Inhibits Neuronal Firing Activities in the Caudal
... in the CVLM. These neurons may also display different neuronal firing patterns. Our study also showed that the inhibitory effect of propofol on different neurons in the CVLM was not homogeneous, with some potent inhibitions and some mild inhibitions detected. We also found that some neurons were ins ...
... in the CVLM. These neurons may also display different neuronal firing patterns. Our study also showed that the inhibitory effect of propofol on different neurons in the CVLM was not homogeneous, with some potent inhibitions and some mild inhibitions detected. We also found that some neurons were ins ...
- Journal of Vestibular Research
... D Abstract- This theoretical paper describes the "intrinsic mechanism hypothesis," a new hypothesis of vestibular compensation, the behavioral recovery that follows unilateral deafferentation of the vestibular labyrinth (UVD). The most salient characteristic of vestibular compensation is the decreas ...
... D Abstract- This theoretical paper describes the "intrinsic mechanism hypothesis," a new hypothesis of vestibular compensation, the behavioral recovery that follows unilateral deafferentation of the vestibular labyrinth (UVD). The most salient characteristic of vestibular compensation is the decreas ...
Potential switch from eupnea to fictive gasping after blockade of
... both a direct modulation of channel conductances and alteration of ionic homeostasis in the extracellular environment. Specifically, hypoxia suppresses several types of voltage-gated potassium channels (4, 9, 16, 20, 21, 49), activates persistent sodium channels (13, 15, 17), and induces an augmenta ...
... both a direct modulation of channel conductances and alteration of ionic homeostasis in the extracellular environment. Specifically, hypoxia suppresses several types of voltage-gated potassium channels (4, 9, 16, 20, 21, 49), activates persistent sodium channels (13, 15, 17), and induces an augmenta ...
Changes in Resting-State Functional Connectivity Following Delay
... The development of non-invasive methods of functional imaging has led to a better understanding of the neural processes that occur in humans while they are forming or using a memory. However, these advancements led to studies that have primarily focused on the neural activity evoked by stimuli prese ...
... The development of non-invasive methods of functional imaging has led to a better understanding of the neural processes that occur in humans while they are forming or using a memory. However, these advancements led to studies that have primarily focused on the neural activity evoked by stimuli prese ...
In 1978 Mountcastle hypothesized that the smallest functional unit of
... (“mosaic”) made up of discrete place-defined macrocolumns – “segregates”– in the region of cat and monkey somatosensory cortex which receives input from forelimb skin, also proposed that discrete place-defined macrocolumns are a common mode of topographic organization throughout somatosensory cortex ...
... (“mosaic”) made up of discrete place-defined macrocolumns – “segregates”– in the region of cat and monkey somatosensory cortex which receives input from forelimb skin, also proposed that discrete place-defined macrocolumns are a common mode of topographic organization throughout somatosensory cortex ...
Kobayashi S, Kawagoe R, Takikawa Y, Koizumi M, Sakagami M
... reward availability on each trial was not directly instructed; the information of reward availability could be obtained by combining CUE-dir information with RWD-dir information on each trial. When CUE-dir and RWD-dir were both in the same direction A (denoted as RWDA–CUEA), or both in the same dire ...
... reward availability on each trial was not directly instructed; the information of reward availability could be obtained by combining CUE-dir information with RWD-dir information on each trial. When CUE-dir and RWD-dir were both in the same direction A (denoted as RWDA–CUEA), or both in the same dire ...
Altered Resting-State Functional Connectivity of
... first three volumes were discarded to account for magnetic field stabilization. The spatial resolution of the functional and structural images was similar to published studies examining resting-state connectivity of amygdala complexes (Etkin et al, 2009; Roy et al, 2009; Roy et al, 2013). Participan ...
... first three volumes were discarded to account for magnetic field stabilization. The spatial resolution of the functional and structural images was similar to published studies examining resting-state connectivity of amygdala complexes (Etkin et al, 2009; Roy et al, 2009; Roy et al, 2013). Participan ...
The effect of selective attention on auditory frequency
... processed in close vicinity at AC. The tonotopy set limits to the frequency resolution, but under selective attention the frequency-based segregation succeeds even in conditions where the signal and noise are overlapping in frequency. The aim of the study was to explore these underlying short-term n ...
... processed in close vicinity at AC. The tonotopy set limits to the frequency resolution, but under selective attention the frequency-based segregation succeeds even in conditions where the signal and noise are overlapping in frequency. The aim of the study was to explore these underlying short-term n ...
View/Open - DukeSpace
... The paradox of the SEF – that it seems so saccade related but is so blatantly unnecessary for generating saccades – and the early findings on multiple coordinate systems in the SEF inspired a new generation of experiments that have been very informative. This nascent research posits a higher level f ...
... The paradox of the SEF – that it seems so saccade related but is so blatantly unnecessary for generating saccades – and the early findings on multiple coordinate systems in the SEF inspired a new generation of experiments that have been very informative. This nascent research posits a higher level f ...
A review of MRI findings in schizophrenia
... setting the stage for the development of the symptoms of schizophrenia. Or there may be additional factors, such as stress or neurotoxicity, that occur during adolescence or early adulthood and are necessary for the development of schizophrenia, and may be associated with neurodegenerative changes. ...
... setting the stage for the development of the symptoms of schizophrenia. Or there may be additional factors, such as stress or neurotoxicity, that occur during adolescence or early adulthood and are necessary for the development of schizophrenia, and may be associated with neurodegenerative changes. ...
Neural Correlates of Knowledge: Stable Representation of Stimulus
... the subject must identify the stimulus that has been paired with the cue (e.g., an umbrella). To perform correctly the subject must access their knowledge of the stimulus pairing at some time between when the cue is presented and the choice is made. Using the PA task, previous studies have shown tha ...
... the subject must identify the stimulus that has been paired with the cue (e.g., an umbrella). To perform correctly the subject must access their knowledge of the stimulus pairing at some time between when the cue is presented and the choice is made. Using the PA task, previous studies have shown tha ...
Functional Microarchitecture of Cat Primary Visual Cortex
... width showed no such clustering. By investigating the temporal patterns of neighbouring neurons in response to movies, visual noise and gratings, we found that stimulus-dependent responses, called “signals”, showed only small correlations (magnitude) on short time scales (10200 ms). The strengths of ...
... width showed no such clustering. By investigating the temporal patterns of neighbouring neurons in response to movies, visual noise and gratings, we found that stimulus-dependent responses, called “signals”, showed only small correlations (magnitude) on short time scales (10200 ms). The strengths of ...
Novelty exploration training tasks - Repositório da Universidade de
... significant decrease in sympathetic tone, however it did not affect systolic, diastolic and mean blood pressure values. Additionally, no deleterious effects on cardiorespiratory reflexes, metabolic parameters and locomotor plus exploratory activity were observed. In hypertensive conditions, 60 days ...
... significant decrease in sympathetic tone, however it did not affect systolic, diastolic and mean blood pressure values. Additionally, no deleterious effects on cardiorespiratory reflexes, metabolic parameters and locomotor plus exploratory activity were observed. In hypertensive conditions, 60 days ...
Document
... Figure 2. Entrainment of circadian rhythms: the Phase Response Curve Much has been learned about the synchronization of the biological clock to the environmental light-dark cycle by placing animals in constant darkness and measuring the effect of brief light pulses on the timing of their behavior. H ...
... Figure 2. Entrainment of circadian rhythms: the Phase Response Curve Much has been learned about the synchronization of the biological clock to the environmental light-dark cycle by placing animals in constant darkness and measuring the effect of brief light pulses on the timing of their behavior. H ...
Signal processing methods in Sleep Research
... Slow wave sleep predominates in the first third of the night and is linked to the initiation of sleep. REM sleep predominates in the last 3rd of the night. Wakefulness in sleep usually accounts for less than 5% of the night. N1 generally constitutes 2 to 5% of sleep. N2 generally constitutes 45 to 5 ...
... Slow wave sleep predominates in the first third of the night and is linked to the initiation of sleep. REM sleep predominates in the last 3rd of the night. Wakefulness in sleep usually accounts for less than 5% of the night. N1 generally constitutes 2 to 5% of sleep. N2 generally constitutes 45 to 5 ...
Electrophysiological markers of Rapid Eye Movements in
... Rapid eye movements can be defined as fast rotatory ocular movements. This definition embraces a great variety of eye movements including saccades performed by awake individuals, a phenomenon extensively studied and one of the hallmarks of cognitive sciences. Saccades permit individuals to rapidly m ...
... Rapid eye movements can be defined as fast rotatory ocular movements. This definition embraces a great variety of eye movements including saccades performed by awake individuals, a phenomenon extensively studied and one of the hallmarks of cognitive sciences. Saccades permit individuals to rapidly m ...
Functional magnetic resonance imaging

Functional magnetic resonance imaging or functional MRI (fMRI) is a functional neuroimaging procedure using MRI technology that measures brain activity by detecting associated changes in blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases.The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not require people to undergo shots, surgery, or to ingest substances, or be exposed to radiation, etc. Other methods of obtaining contrast are arterial spin labeling and diffusion MRI.The procedure is similar to MRI but uses the change in magnetization between oxygen-rich and oxygen-poor blood as its basic measure. This measure is frequently corrupted by noise from various sources and hence statistical procedures are used to extract the underlying signal. The resulting brain activation can be presented graphically by color-coding the strength of activation across the brain or the specific region studied. The technique can localize activity to within millimeters but, using standard techniques, no better than within a window of a few seconds.fMRI is used both in the research world, and to a lesser extent, in the clinical world. It can also be combined and complemented with other measures of brain physiology such as EEG and NIRS. Newer methods which improve both spatial and time resolution are being researched, and these largely use biomarkers other than the BOLD signal. Some companies have developed commercial products such as lie detectors based on fMRI techniques, but the research is not believed to be ripe enough for widespread commercialization.