* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Syllabus
Donald O. Hebb wikipedia , lookup
Membrane potential wikipedia , lookup
Action potential wikipedia , lookup
Resting potential wikipedia , lookup
Apical dendrite wikipedia , lookup
Biology and consumer behaviour wikipedia , lookup
Binding problem wikipedia , lookup
Neurocomputational speech processing wikipedia , lookup
Long-term potentiation wikipedia , lookup
Neural oscillation wikipedia , lookup
NMDA receptor wikipedia , lookup
Electrophysiology wikipedia , lookup
Embodied cognitive science wikipedia , lookup
Single-unit recording wikipedia , lookup
Artificial neural network wikipedia , lookup
Endocannabinoid system wikipedia , lookup
Cognitive neuroscience wikipedia , lookup
Long-term depression wikipedia , lookup
Central pattern generator wikipedia , lookup
Feature detection (nervous system) wikipedia , lookup
Dendritic spine wikipedia , lookup
Neuroeconomics wikipedia , lookup
Biological neuron model wikipedia , lookup
Neuroethology wikipedia , lookup
Caridoid escape reaction wikipedia , lookup
Recurrent neural network wikipedia , lookup
Types of artificial neural networks wikipedia , lookup
Optogenetics wikipedia , lookup
Holonomic brain theory wikipedia , lookup
Neuroplasticity wikipedia , lookup
Neuroanatomy wikipedia , lookup
Signal transduction wikipedia , lookup
Neuromuscular junction wikipedia , lookup
Neurotransmitter wikipedia , lookup
Synaptic noise wikipedia , lookup
Metastability in the brain wikipedia , lookup
Neural engineering wikipedia , lookup
Nervous system network models wikipedia , lookup
Clinical neurochemistry wikipedia , lookup
End-plate potential wikipedia , lookup
Stimulus (physiology) wikipedia , lookup
Neuropsychopharmacology wikipedia , lookup
Synaptic gating wikipedia , lookup
Development of the nervous system wikipedia , lookup
Channelrhodopsin wikipedia , lookup
Molecular neuroscience wikipedia , lookup
Chemical synapse wikipedia , lookup
Synaptogenesis wikipedia , lookup
MCB 160: Cellular & Molecular Neuroscience (MWF lecture + required discussion, 4 units) An introductory survey of designed to provide a general understanding of the nervous system including how it functions, how it develops, and how it changes with learning and memory. Analysis from the level of molecules to cells to simple circuits to complex networks to higher brain functions. First half of the introductory 160-‐ 161 sequence. Required textbook: Kandel et al., Principles of Neural Science, 5th Ed. One chapter will be assigned for each lecture. Grading: 25% Midterm 1, 25% Midterm 2, 50% Final Exam. Fall. Staff. 1 Introduction. Gross anatomy. Golgi vs. Cajal in the neuron doctrine. Structure of a neuron. Cell types. Cellular neurophysiology 2 The plasma membrane 3 Passive electrical properties of neurons 4 Origin of the membrane potential 5 Selective permeability of ion channels 6 Gating of ion channels 7 The action potential 8 Propagation of action potentials The synapse 9 Physiology of synaptic transmission 10 Molecular mechanisms of exocytosis and endocytosis 11 Postsynaptic receptors (ionotropic) 12 Synaptic excitation, inhibition, and integration 13 Neurotransmitters MIDTERM 1 14 Metabotropic receptors, intracellular messengers and neuromodulation 15 Dendrites, spines, and dendritic excitability 16 Preview of neural circuits and systems. A simple, completely understood sensorimotor pathway: crayfish tail flip escape response. Basic architecture of mammalian sensory and motor pathways. Synaptic plasticity 17 Synaptic plasticity and learning: Aplysia as case study 18 Short-‐term plasticity 19 LTP 20 LTD, STDP, and structural synaptic plasticity Sensory transduction 21 Phototransduction in rods & cones 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 Retinal processing of vision (*illustrates synaptic integration, inhibition) Evolution of color vision (or maybe melanopsin and circadian rhythms) Transduction for taste & olfaction Olfactory processing (*illustrates synaptic target selection, circuit construction) Pain and temperature transduction MIDTERM 2 Motor neurons and muscle Neural development Neural differentiation Axon guidance Synapse formation Activity-‐dependent synaptic refinement Neural repair and aging; stem cells and adult neurogenesis Regeneration in PNS and CNS Molecular basis of behavior and disease Genes, circuits & behavior (Drosophila courtship or C. elegans escape) Genes, circuits & behavior (Social behavior in prairie voles) Traumatic brain injury and epilepsy Neurodevelopmental and neurodegenerative diseases Optical methods in neurobiology