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Ch 46-47 Wrap-up Urchin Gastrulation ( proto or deuterostome ? ) Triploblastic (know 3 layers/colors) Archenteron, blastocoel Nerve cord? Notochord? Primitive streak What structure(s) does each layer give rise to? Organogenesis (differentiation) happens very early Table 47.1 GERM LAYER ECTODERM ENDODERM MESODERM p. 945 Organs and tissues formed Skin, cornea and lens of eye, nervous system (neural tube), mouth and rectum Digestive tract lining, respiratory system lining, many organs Notochord, skeleton, muscles, circulatory systems, reproductive system, excretory system Ch. 48 Nervous Systems Nervous system afferent interneurons efferent PNS, CNS INPUT: Effector cells Sensory Neurons (receptors) INTEGRATION: CNS(brain & spinal cord) Interneurons OUTPUT: Motor Neurons (effectors) The Reflex Arc The Neuron Dendrites receive the signal, axon delivers the signal away to another neuron or to the CNS Myelin sheaths (white matter) insulate the axon and are made by Schwanns cells or oligodendrocytes. Schwanns and Oligodendrocytes are both types of supporting cells called glia. What is saltatory conduction? P.970 What is a Node of Ranvier? What is a synapse? Anatomy of a Neuron Makes myelin - PNS >Speed of Transmission: Larger axons & Myelin sheath (Saltatory conduction) Outside is always zero Less (+) inside = “-” inside and “+” outside -70 mV is the resting membrane potential What makes a signal travel down the axon ? 0 Action Potential (“all or none” nerve impulse) K+ out of EPSP the cell -50 Threshold Potential reached: -50 -70 Membrane potential (mV) +35 Na+ into the cell Na/K pump restores Hyperpolarization from ___ ions 0 1 2 3 4 Time (milliseconds) resting state restored (-70) Hyperpolarization: more negative inside by K+ moving out—does not cause an action potential Depolarization: inside gains more positive charge by Na+ rushing in EXCITATORY (+) -70 What is meant by all–or–none action potential? The steps of an action potential… Resting State + Na gates closed, K+ gate closed Na/K pump is maintaining –70mV Depolarizing Phase Na+ gate OPENS, (fast gate) + K channels are still closed (slow gate) Na+ rushes into the neuron (+ + + +) RE-polarizing Phase + Na inactivation gate closes, K+ slow gate OPENS K+ rushes out of the neuron Undershoot + Na channels closed, K+ channels still OPEN K+ still rushes out of the neuron (Hyperpolarizing the inside - - - - - -) Direction of transmission? Slow closing of the K+ channels prevents “backflow” One way flow of Electricity! Chemical synapses TERMS: Vesicles synaptic cleft neurotransmitters (Ca2+) receptor ion channel Pre/post synaptic membrane Enzymes to degrade the neurotransmitters Summation of IPSP & EPSP Inhibitory(-) & Excitatory(+) Post-Synaptic Potential Temporal and Spatial Summation PNS AUTONOMIC Sympathetic Stress (like Parasympathetic Peace a “fight or flight” response) (relaxed, normal functions) The real thing . . . . . . . . Cerebrum Thalamus Hypothalamus Cerebellum Brain stem: medulla oblongata, pons, midbrain Cerebrum Right versus left Cerebrum BRAIN STRUCTURES AND FUNCTIONS Brain Stem: Medulla Oblongata & Pons = (autonomic, homeostatic, data conduction) Midbrain = (receives and integrates sensory information) Cerebellum: Automatic coordination of movements and balance Thalamus:integration of stimuli coming to the brain Hypothalamus: important homeostatic regulation (temperature, hunger, thirst) & hormones Cerebrum: memory, learning , emotions, motor movements, sensory cortex areas