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Nervous System Chapter 35 Vocabulary 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. muscle tissue epithelial tissue connective tissue nervous tissue negative feedback neuron cell body dendrite axon myelin sheath resting potential action potential synapse neurotransmitter 15. 16. 17. 18. 19. central nervous system cerebrum cerebellum brain stem reflex I. How Nerve Cells Communicate Nervous system = controls and coordinates functions throughout the body and responds to internal and external stimuli B. Neurons = cells that transmit electrical signals (impulses) 1. 3 types of neurons = sensory, interneurons, motor 2. Parts of neuron a. cell body = contains nucleus and cytoplasm b. dendrites = branched extensions that receive stimuli from the environment or from other neurons, impulse goes toward the cell body c. axon = a long fiber that carries impulses away from the cell body, ends in axon terminals d. mylein sheath = insulating membrane around axon, nodes (gaps) allow impulse to jumps from one to the other increasing speed of impulse A. DRAW Figure 35-5, pg 897 Neuron dendrites cell body nodes axon terminals axon myelin sheaths C. Nerve Impulse 1. Resting Neuron a. electrical charge of neuron is from charged ions b. At rest, outside of the cell has a net “+”charge, and the inside has a net “-” charge. c. resting potential = electrical charge difference of a neuron at rest btwn. the outside and inside is -70 mVolts d. “sodium-potassium pump” in membrane pumps Na+ ions out of the cell & K+ into the cell by active transport (takes energy) 2. Moving Impulse a. an impulse begins when a neuron is stimulated by another neuron or by the environment b. the gates within the sodium channels open, allowing positively charged Na+ ions to flow inside the cell, inside temporarily becomes more “+” than the outside c. internal charge goes from -70 mVolts to +30 mVolts _ + _ + _ + +_ d. action potential = reversal of charges, from negative to positive, is called a nerve impulse e. influx of sodium stimulates the opening of potassium pores and K+ flows out f. Now all of the sodium is inside and the potassium is outside How does the cell go back to its original condition? g. The sodium/potassium pump kicks in to restore the resting potential. DRAW Figure 35-7, pg 899 + _ _ _ + h. The depolarization on one segment starts a domino effect down the neuron. _ + _ + _ + _ + _ + _ + _ _ + Movement of an Action Potential 3. Threshold a. threshold = minimum level of a stimulus that is required to activate a neuron b. All-or-none nerve impulse a stimulus stronger than the threshold produces an impulse, a stimulus that is weaker than the threshold will produce no impulse 1) like a pushing over a row of dominoes Direction of Impulse Dendrite of adjacent neuron How an Impulse Moves Between Two Neurons Axon Vesicle Receptor Axon terminal Synaptic cleft Neurotransmitter D. Synapse 1. synapse = gap between the axon of one neuron and the dendrites or cell body of the next neuron 2. When the impulse reaches the end of the axon chemicals called neurotransmitters are released and carry the signal to the next neuron. 3. Overall impulse pathway: Electrical --> Chemical --> Electrical DRAW Figure 35-8, page 900 II. Divisions of Nervous System A. Overall Functions 1. 2. 3. B. Sensory input – vision, hearing, balance, smell, taste, and touch Motor output – muscle contraction and movement Memory and integration of information Central Nervous System (CNS) 1. 2. Relays messages, processes info, analyzes info Consists of brain & spinal cord QuickTime™ and a Sorenson Video 3 decompressor are needed to see this picture. C. Brain 1. Cerebrum a. Largest region; folds and grooves increase surface area b. Controls voluntary activities and all higher brain functions (intelligence, learning and judgment) c. Right and left hemispheres that are connected by corpus callosum Cerebrum Corpus callosum 2. Cerebellum a. Center for balance and coordination of voluntary muscle movements. Cerebellum 3. Brain Stem a. Relays information between brain and spinal cord b. Comprised of the pons and medulla oblongata c. Work together to control breathing, heart rate, blood pressure, digestion, and swallowing. Pons Medulla oblongata 4. Thalamus a. Relay station for all sensory input to the cerebrum. 5. Hypothalamus a. Homeostatic center that controls endocrine system (hormones), body temperature, thirst, hunger, anger and fatigue Thalamu s Hypothalamus Cerebrum Thalamus Pineal gland DRAW Figure 35-9, pg 901 Hypothalamus Cerebellum Pituitary gland Pons Medulla oblongata Spinal cord D. Spinal Cord 1. 2. 31 pairs of nerves branch out from the spinal cord Functions a. Carries info to and from brain to body b. Reflex center Gray matter Central canal Spinal nerve White matter Meninges E. Reflexes 1. reflexes = quick, automatic response to a stimulus 2. 5-part reflex arc: a. Sensory receptor reacts to stimulus (heat on finger) b. Impulse is carried to the spinal cord by a sensory neuron c. In the spinal cord, the impulse is transferred to a motor neuron d. Motor neuron conducts a nerve impulse to an effector (arm muscles) e. Effector responds to the impulses by contracting (hand gets pulled away from the heat) Reflexes: DRAW Fig. 35-11 pg 904 F. Peripheral Nervous System (PNS) 1. 2. 3. Sensory neurons transmits impulses from sense organs to CNS Interneurons connect sensory and motor neurons in spinal cord Motor neurons transmits impulses from CNS to the muscles or glands a. Somatic NS (voluntary) responds to external stimuli 1) Regulates activities that are under conscious control (e.g. picking your nose) 2) Some reflex control b. Autonomic (involuntary) NS respond to internal stimuli; two divisions: 1) Sympathetic - ↑ energy consumption (increase HR) 2) Parasympathetic - ↓ energy consumption (decrease HR) 3) Both help maintain homeostasis by having opposing effects G. Nervous System Graphic Organizer Nervous System is divided into Central nervous system Motor nerves Somatic nervous system that make up Sympathetic nervous system Peripheral nervous system which consists of Autonomic nervous system which is divided into Parasympathetic nervous system Sensory nerves III. The Senses A. 5 General Sensory Receptors: pain, thermo-, mechano-, chemo- and photoreceptors. Where do you think these different types of receptors are found and what is their function? Take YOUR OWN NOTES on 35-4 pg 906-909 B. C. D. E. Vision Hearing and Balance Smell and Taste Touch IV. Drugs A. Drug = any substance, other than food, that changes the structure or function of the body 1. 2. 3. B. The most powerful drugs affect the nervous system Addiction = an uncontrollable dependence on a drug Drug abuse = can be defined as using any drug in a way that most doctors would not approve Narcotics 1. 2. 3. narcotic = substance that blunt the senses decreasing pain ex: opium, morphine, codeine, heroin Heroin - increases release of dopamine, over-stimulation of neurons a. Effects – intense rush, pleasure, decrease of heart rate and breathing, decrease pain b. Problems – receptors become used to this over-stimulation and need more heroin just to work normally (rapid addiction), overdose causes breathing to stop C. Stimulants 1. stimulant = substance that increases heart rate, blood pressure, and breathing rate a. Increases the release of neurotransmitters; leads to release of energy and feeling of well-being, relieves pain b. When effect wears off, brain’s supply is depleted leaving the user depressed and fatigued c. Ex: cocaine, amphetamines (crystal meth, speed, ice, crank), ecstasy, ritalin, nicotine, and caffeine 2. Cocaine/crack – blocks dopamine reuptake by neurons causing a “flood” of dopamine in the brain a. Effects – euphoria and relaxation b. Problems – highly addictive, heart attacks, delirium, strokes, hypertension Cocaine Cocaine and Your Brain In the synapse, or space between neurons (area of detail), cocaine binds to dopamine reuptake transporters, causing a "flood" of dopamine in the brain. 3. Meth / Speed - damages axon terminals a. Effects – temporary mood elevation, exhilaration (high), increased mental alertness, wakefulness b. Problems -- extremely addictive (sometimes with just one use), very jittery high, along with anxiety, insomnia, sometimes paranoia, can cause convulsions, heart irregularities, high blood pressure, depression, restlessness, tremors, severe fatigue, overdose can cause coma and death 4. Ecstasy - damages axon terminals a. Effects – damages axon terminals, increased energy, peacefulness b. Problems – teeth clenching, water regulation, increased heart rate and blood pressure, heart, liver, or kidney failure, permanently damages axon terminals affecting mood, sleep, and memory ECSTASY Serotonin travels through the healthy brain across the synapse. Ecstasy use damages the axon terminals (ends) of neuron fibers. Chemical messages relating to mood, sleep, memory, and more are disrupted. D. Depressants – suppresses CNS actions 1. 2. 3. Effects – relieve anxiety, irritability, tension, produce a state of intoxication Ex: tranquilizers, barbiturates, marijuana, alcohol Marijuana a. b. 4. THC disrupts coordination of nerve impulses in the brain long term – more lung damage than cigarettes, memory loss, attention deficit, decreased levels of testosterone, abnormal sperm Alcohol a. b. c. d. blocks receptors making the neuron less excitable & increases dopamine physical and mental impairment, depression, liver damage destroys liver cells involved in 1/3 of all automobile crashes, involved in 1/3 of all homicides E. Inhalants – decreases O2 to the brain, poisons body 1. Effects – makes you feel light-headed or dizzy for several minutes 2. Problems – death can result from 1st time, kidney and liver damage, decreased muscle size, loss of smell an hearing over time, brain damage 3. Ex: glue, gasoline, nail polish remover, aerosols Inhalants Cheap high, quick buzz You can die the first time you try inhalants. Sudden Sniffing Death – sudden heart failure Asphixiation (lack of O2) Inhalants damage or destroy myelin. Healthy myelin helps speed messages from cell to cell in your brain. When myelin is damaged, your muscles won't be able to obey your brain.