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General Psychology Chapter 2 Neuroscience & Behavior Sarah Rach • Everything psychological – every idea, every mood, every urge – is simultaneously biological “To think, feel, or act without a body would be like running without legs.” Neural Communication • The reason we can study other animals • Human brain = monkey brain • Our brains are more complex than a rat’s but both follow the same principles Neurons • Neuron: a nerve cell – the building block of the nervous system • Dendrite: bushy, branching extensions of a neuron that receive messages and conduct impulses toward the cell body (LISTENS) • Axon: the extension of a neuron, ending in branching terminal fibers, through which messages pass to other neurons or to muscles or glands (SPEAKS) • Can be very long (several feet) • Neuron carrying orders to a leg muscle = basketball attached to a rope 4 miles long A Motor Neuron Neurons continued… • Action Potential: a neural impulse; a brief electrical charge that travels down an axon • 2 miles per hour – 200 miles per hour • Excitatory signals: like pushing a neuron’s accelerator • Inhibitory: like pushing its break • Threshold: the minimum intensity of a neuron • If the excitatory signals minus inhibitory signals exceeds the threshold – the signals combined trigger an action potential • All-or-None: increasing the level of stimulation above the threshold will not increase the neural impulse’s intensity • More can be fired • They can fire more often • So we can differentiate between gentle or hard sensations How Neurons Communicate • Synapse: the junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron • The tiny gap at this junction is called the synaptic gap or cleft • Less than one millionth of an inch wide How Neurons Communicate How Neurons Communicate • Dendrites and axons don’t quite touch…so how do they communicate? • Neurotransmitters: chemical messengers that traverse the synaptic gaps between neurons • When released by the sending neuron, neurotransmitters travel across the synapse and bind to receptor sites on the receiving neuron, thereby influencing whether that neuron will generate an impulse • Reuptake: the sending neuron normally reabsorbs excess neurotransmitter molecules Neurotransmitters • Acetylcholine (Ach): one of the best-understood neurotransmitters • Is the messenger at every junction between a motor neuron and skeleton muscle • When Ach is released to our muscle cells, the muscle contracts • Endorphins (endogenous produced within morphine) • Natural opiates released in response to pain and vigorous exercise • “runner’s high” • Painkilling effects of acupuncture • Indifference to pain in some severely injured people Drugs & Chemicals Affect on Neurotransmitters • Agonists: Excite • similar enough to a neurotransmitter to mimic its effects or it may block the neurotransmitter’s reuptake • Antagonists: inhibit • Inhibit a neurotransmitter’s release from the sending neuron • Others are enough like the neurotransmitter to occupy its receptor site and block its effect, but are not similar enough to stimulate the receptor • Foreign coins that fit into, but won’t operate, a pop or candy machine • Blood-Brain Barrier: fences out unwanted chemicals circulating in the blood • Makes it difficult to create new drugs to be used to treat disorders because they can’t cross the barrier The Nervous System • Central Nervous System (CNS) • Brain and spinal cord • Peripheral Nervous System (PNS) • Links the central nervous system with the body’s sensory receptors, muscles, and glands • Nerves • Neural “cables” containing many axons Information travels in the nervous system through three types of neurons • Sensory Neurons – carry messages from the body’s tissues and sensory organs inward to the brain and spinal cord, for processing • Motor Neurons – neurons that carry outgoing information from the central nervous system to the muscles and glands • Interneurons – central nervous system neurons that internally communicate and intervene between the sensory inputs and motor outputs Peripheral Nervous System Peripheral Nervous System • Somatic Nervous System • Enables voluntary control of our skeletal • Autonomic Nervous System • Controls our glands and the muscles of our internal organs (glandular activity, heartbeat, digestion) • Automatic pilot (autonomously) – but may be consciously overridden • Sympathetic: arouses and expends energy – gets your ready for action • Accelerate your heartbeat, raise your blood pressure, slow your digestion, raise you blood sugar, cool you with perspiration • Parasympathetic: conserves energy as it calms you • Decreasing your heartbeat, lowering your blood sugar, etc. • Work together to keep us in a steady internal state Central Nervous System • Neural networks • neurons cluster into work groups • So they can have fast, short connections • Reflexes • Simple, automatic response to a sensory stimulus, such as the knee-jerk response • Pain reflex – hand will jerk from a flame before your brain receives and responds to the information that causes you to feel pain Endocrine System • The body’s “slow” chemical communication system; a set of glands that secrete hormones into the bloodstream • Hormones • Travel through the bloodstream and affect other tissues, including the brain • Influence our interest in sex, food, and aggression Influential Glands • Adrenal Glands: • Epinephrine (adrenaline) • Norepinephrine (noradrenaline) • Increase heart rate, blood pressure, blood sugar – create a surge of excitement that can linger a while • Pituitary Gland: • • • • • Most influential gland Pea-sized structure located in the core of the brain Controlled by an adjacent brain area (hypothalamus) Releases hormones that influence growth Also influence the release of hormones by other endocrine glands The Brain • When we’re thinking about our brain, we’re thinking with our brain • The mind is what the brain does Older Brain Structures • Brainstem • The brain’s basement • Oldest and innermost region • Medulla • Where the spinal cord enters the skull and swells slightly • Controls your heartbeat and breathing • Pons • Just above the medulla • Helps coordinate movements More older brain structures… • Thalamus • A joined pair of egg-shaped structures • Receives information from all the senses except smell and routes it to the brain regions that deal with seeing, hearing, tasting, and touching • Receives some of the higher brain’s replies, which it then directs to the medulla and to the cerebellum • Reticular Formation • Inside the brainstem, between your ears • Finger shaped network of neurons that extends from the spinal cord right up to the thalamus • Filters incoming stimuli and relays important information to other areas of the brain • Is involved in arousal Older brain structures • Cerebellum • • • • Means “little brain” Extends from the rear of the brainstem Base-ball sized Enables one type of nonverbal learning and memory • Helps us judge time, modulate our emotions, and discriminate sounds and textures • Coordinates voluntary movement • Note: the older brain functions all occur without any conscious effort • Our brain processes most information outside of our awareness Limbic System • Doughnut-shaped • Links to emotions (fear and anger) and to basic motives (food and sex) • Amygdala • Two lima bean-sized neural clusters • Influence aggression and fear • Removed in an ill-tempered monkey • Turned very mellow • Stimulated in a domestic cat • Hissing, prepares to attack • Moved a bit – cowers from a mouse • Hypothalamus • Hypo = below (the thalamus) • Some parts influence hunger, thirst, body temperature, sexual behavior • Reward centers • Reward deficiency syndrome Cerebral Cortex • Thin surface layer of interconnected neural cells • Your body’s ultimate control and information-processing center • Contains 20-23 billion nerve cells • 300 trillion synaptic connections “being human takes a lot of nerve” Functions of the Cortex • Motor Functions • Motor cortex – runs from ear-to-ear across the top of the head • Stimulating parts of the brain in the left or right hemisphere caused movements of specific body parts on the opposite side of the body • Areas of the body requiring precise control (fingers, mouth) occupy the greatest amount of cortical space Functions of the Cortex • Sensory Functions • Parallel to the motor cortex & just behind the front of the parietal lobes • Specializes in receiving information from the skin senses and from the movement of body parts Association Areas • Three-fourths of the think wrinkled layer of the cerebral cortex • Neurons in this area integrate information, linking sensory inputs with stored memories • Association areas are found in all four lobes Association Areas • More intelligent animals have increased “uncommitted” or association areas of the cortex Language: Specialization & Integration • Aphasia • Impaired use of language • Some people with this can speak fluently but cannot read • Some can write but not read, read but not write, read numbers but not letters • Broca’s Area • A specific area of the left frontal lobe, where if damage occurs, muscle movements involved in speech are impacted • Struggle to form words, yet could often sing familiar songs with ease • Wenicke’s Area • A specific area of the left temporal lob, where if damage occurs, people could only speak meaningless words and were unable to comprehend others’ words The Brain’s Plasticity • Plasticity – its ability to modify itself after some types of damage • Some neural tissue can reorganize in response to damage • Most plastic when we are young children • If a blind person uses one finger to read Braille, the brain area dedicated to that finger expands as the sense of touch invades the visual cortex that normally helps people see • Lose a finger and the sensory cortex that received its input will begin to receive input from the adjacent fingers, which then become more sensitive • Adult mice and humans can also generate new brain cells Splitting the Brain • The brain’s two sides serve differing functions • Lateralization – hemispheric specialization • Corpus callosum – wide band of axon fibers connecting the two hemispheres and carrying messages between them • Split brained people are surprisingly normal – their personality and intellect hardly affected Left Hemisphere Right Hemisphere Information from the right visual field comes here Information from the left visual field comes here Speech is controlled here – they will say what they saw in the right visual field Controls the left hand – will point to the word that they saw in their left visual field Hemispheric Differences • Right Hemisphere • Perceptual tasks performed will cause brain waves, blood flow, and glucose consumption to increase, which shows activity in the right hemisphere • Excels in making inferences based on language • Left Hemisphere • Speaking or calculating – will increase activity in the left hemisphere • Adept to making quick, literal interpretations of language • Deaf people are enabled to process sign language here • Just as hearing people use the left hemisphere to process speech, deaf people use the left hemisphere to read signs • To the brain, language is language, whether it is spoken or signed Which way is she spinning? • If you see her spinning to the right, then your right brain is working and if you see her spinning to the left, then your left brain is working Just for fun…