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UNIT 7 Part 2: The Nervous System Key Questions 1. How do humans coordinate all body systems? 2. What parts make up the nervous system? 3. What role do chemicals and receptors play in the nervous system? 4. How do organisms maintain dynamic equilibrium in response to stimuli (internal/external)? 5. How do feedback mechanisms allow organisms to maintain homeostasis? 6. What happens if there are disruptions in homeostasis regarding the nervous system? REMEMBER!!!! REGULATION: Control and coordination of all life functions to maintain homeostasis. REMEMBER!!! Human body systems that involve regulation: Nervous system and Endocrine system NERVOUS SYSTEM A. Definitions: Impulse: Electro-chemical signal carried along a nerve pathway. Receptor: Specialized structures that detect a stimulus. RECEPTORS Tons of sensory neurons found here!!! NERVOUS SYSTEM Effector: Structure that carries out a response (muscles, glands). Stimulus: Anything that causes a response. Response: Reaction to a stimulus. STIMULUS/RESPONSE NERVOUS SYSTEM Neurotransmitter: Chemical secreted to help to transmit impulses from neuron to neuron. Reflex: A quick, automatic response to a stimulus. Examples: sneezing, blinking. REFLEX Normal reflex for an infant when he or she is startled or feels like they are falling. The infant will have a "startled" look and the arms will fling out sideways with the palms up and the thumbs flexed. Videos Video – ‘Neuron’ – on server (part at beginning) NOTES-NERVOUS SYSTEM A. Structures of the Nervous System: Neurons: Basic unit of function of the nervous system (See Diagram). NERVOUS SYSTEM Transmit impulses in one direction. NERVOUS SYSTEM PARTS OF THE NEURON: DCATS Dendrites: Connect stimuli to neuron and generate impulses toward cell body. Cell Body: Contains nucleus. NERVOUSE SYSTEM Axon: Fibers wrapped in myelin sheath (fat coating) Transmits impulses away from cell body and toward terminal branches. NERVOUS SYSTEM Terminal branches: End of neuron. Secretes neurotransmitters. Dendrite on next nerve catches the neurotransmitter and initiates signal again. NERVOUS SYSTEM Synapse: Space between adjacent neurons. Neuron Diagram What is the ‘funny bone?!’ http://kidshealth.org/kid/talk/qa/funny_bone.ht ml Video Video – ‘Nerve Impulses’ (server) Video – ‘Neurotransmitters’ (server) NERVOUS SYSTEM FYI: You are born with all of the nerve cells you will ever have. They cannot divide, so they cannot be replaced. Many drugs affect the nervous system. Example: Many pain killers block neurotransmitters from being secreted, therefore the impulse is blocked, and you do not feel pain. NERVOUS SYSTEM 3 Types of Neurons: 1. Sensory Neuron – Transmits impulses from receptors to brain and spinal cord. Sense organs = structures where sensory neurons are concentrated (eyes, ears, skin, tongue). SENSORY NEURON NERVOUS SYSTEM FYI: The Senses: The body has millions of neurons that respond to stimuli in the environment. Sensory receptors react to specific stimuli by sending impulses to other neurons and then to the CNS. These receptors are concentrated in sense organs, such as eyes, ears, nose, mouth, and skin. NERVOUS SYSTEM 2. Interneurons – Relay messages from sensory neurons to motor neurons. Found in brain and spinal cord. NERVOUS SYSTEM 3. Motor Neuron – Transmit impulses from central nervous system (brain and spinal cord) to effectors (muscles, glands). NERVOUS SYSTEM Define Reflex Arc: Pathway over which nervous impulses travel. Step 1: A receptor receives a stimulus (ex. hammer to knee). Step 2: Receptor initiates an impulse in a sensory neuron, which carries impulse to spinal cord. NERVOUS SYSTEM Step 3: Within spinal cord, sensory neuron synapses with interneuron, which then synapses with motor neuron. Step 4: Motor neuron transmits impulse to effector (knee kicks out!) REFLEX ARC NERVOUS SYSTEM C. Parts of the Human Nervous System: Nervous System The Nervous system is divided into 2 parts: The central nervous system (CNS) and the Peripheral nervous system (PNS) Nervous System All body functions are coordinated by communication between the central nervous system and the peripheral nerves. NERVOUS SYSTEM 1. Central Nervous System (CNS): Brain and spinal cord Relays messages, processes and analyzes information NERVOUS SYSTEM A. BRAIN Large mass of neurons located in cranial cavity. Has about 100 billion neurons! Surrounded by skull for protection. Controls the other organ systems of the body Activates muscles Causes secretion of chemicals (like hormones) NERVOUS SYSTEM Brain continued: Allows organism to respond to changes in the internal and external environment FYI: 1 of most active organs in body – weighs only a few pounds, but receives 20% of blood pumped by heart! Made of 3 parts that control different functions in body: Cerebrum, cerebellum, medulla NERVOUS SYSTEM 1. Cerebrum: Largest part of brain Center for VOLUNTARY (conscious) activities. Where reasoning, memory, thinking occur. Left hemisphere = (analytical, math ability) and controls right side; right hemisphere = (artistic ability, creativity) and controls left side. Left vs. Right Brain Information! http://www.ucmas.ca/our-programs/whole- brain-development/left-brain-vs-right-brain/ NERVOUS SYSTEM FYI: Cerebrum is made of 2 layers Outer layer • Cerebral cortex – made of gray matter • Gray matter = densely packed nerve cell bodies Inner layer • Made of white matter = bundles of axons with myelin sheaths NERVOUS SYSTEM 2. Cerebellum: 2nd largest region Controls and coordinates MOTOR activities (movement) and aids in maintaining balance. NERVOUS SYSTEM 3. Medulla: Also called brain stem. Connects brain with spinal cord. Controls involuntary activities (breathing, heartbeat, blood pressure, peristalsis) FYI: (Medulla oblongata = lower portion of brain stem) NERVOUS SYSTEM Other parts of brain: Thalamus: Relay station for sensory information NERVOUS SYSTEM Hypothalamus: Below thalamus Controls coordination of nervous and endocrine systems Helps to control body temp, blood pressure, fatigue, emotions, hunger. NERVOUS SYSTEM B. Spinal Cord: Structure that is continuous with brain. Protected by spinal column. NERVOUS SYSTEM Spinal Cord continued: Coordinates activities between brain and other structures. CENTER FOR REFLEX ACTIONS – PART OF REFLEX ARC. Pathway from sensory neurons to interneuron to motor neurons to effector. NERVOUS SYSTEM 2. Peripheral Nervous System (PNS): All nerves in body “around” or outside of the CNS. Transmits impulses from sense organs to central nervous system and from central nervous system to muscles and glands. NERVOUS SYSTEM * The PNS is divided into 2 different systems based on what each group of nerves control. NERVOUS SYSTEM A. Somatic Nervous System: Consists of nerves that coordinate and control the VOLUNTARY (conscious) muscles of the skeletal system (we can control the actions of these muscles) NERVOUS SYSTEM B. Autonomic Nervous System: Consists of nerves that control muscles which are INVOLUNTARY (we cannot control these muscles – they are automatic) NERVOUS SYSTEM Examples: Heartbeat = cardiac muscle Peristalsis = smooth muscle tissue Glands = secretion of hormones. When Things Go Wrong: Disruptions in Homeostasis 1. Alzheimer’s Disease Brain disease that causes problems with memory, thinking, and behavior Progressive disease – worsens over time No cure http://www.alz.org/alzheimers_disease_4719.asp When Things Go Wrong: Disruptions in Homeostasis 2. Stroke When blood supply to part of the brain is interrupted Deprives brain tissue of food and oxygen Brain cells die When Things Go Wrong: Disruptions in Homeostasis 3. Spinal Cord Injuries Due to a blow or fracture that dislocates the vertebrae Complete spinal cord injury – paralyzed below the level of injury When Things Go Wrong: Disruptions in Homeostasis 4. Multiple Sclerosis Disease in which body’s immune system eats away at myelin sheath Interferes with body’s ability to communicate May result in deterioration of nerves When Things Go Wrong: Disruptions in Homeostasis 5. Infections: Meningitis Disease caused by inflammation of the protective membranes covering the brain and spinal cordmeninges. Usually caused by an infection of the fluid surrounding the brain and spinal cord. May develop in response to a number of causes, usually bacteria or viruses, but meningitis can also be caused by physical injury, cancer or certain drugs. When Things Go Wrong: Disruptions in Homeostasis Botulism Botulinum toxin prduced by bacteria is one of most poisonous substances known 1 gram – if dispersed and ingested could kill 2 million people Toxin produces a protein that blocks release of acetylcholine (neurotransmitter) that tells a muscle to contract When Things Go Wrong: Disruptions in Homeostasis Botox – Drug that contains extremely dilute form of the poison Has been found to be safe and effective for various applications http://www.botoxcosmetic.com/Why_Botox.aspx Videos Video – ‘Synesthesia-The Man Who Tasted Shapes’ (on server-12 min.) Video – Anancephaly (on server – 12 min.) Nova – ‘How the Brain Works’