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Module 4 The Brain The Nervous System The Brain  Centerpiece of the nervous system  weighs 1300 - 1400 g  made up of about 100 billion neurons  works by firing millions of synapses and releasing billions of neurotransmitter molecules.  “the most complex living structure on the universe” The Case of Phineas Gage the historical beginnings of the study of the biological basis of behavior Lesions, autopsies, EEG  Lesions: the site and extent of the brain tissue damage are important guides to the kind of disruption in behavior that is observed and vice versa.  Lesioned brains can be autopsied and studies in detail  Electrocephalograms (EEG): Electrodes are attached to the subject’s scalp, and the device records the patterns of brain waves. How do we study the brain?      Autopsies Clinical observations Lesions EEG Neuroimaging Neuroimaging  PET (positron emission tomography) Scan  Radioactive form of sugar is given  Sugar goes to the region of the brain that is active  MRI (magnetic resonance imaging)  uses magnetic fields and radio waves  Generates images that distinguish among different types of soft tissue  Functional MRI  Reveals blood flow, therefore brain activity  Compares successive MRI scans while the patient is performing a task Mapping the Brain The Cerebral Cortex  Functional MRI scan shows the visual cortex activated as the subject looks at faces The Brain  The core (older brain structures)  The limbic system  The cerebral cortex Older/lower brain structures Older Brain Structures Relays sensory input except smell Filters information Controls alertness Heartbeat and breathing Cerebellum Pons Coordinates movements Brainstem Older brain structures  Brainstem – the crossover point  Medulla – autonomic vital functions  Pons – Coordination of movement  Reticular Formation – nerve network  Filters and relays information from spinal cord  Controls arousal and alertness  Thalamus – sensory switchboard for sight, hearing, touch, and taste  Cerebellum - the “little brain” at the rear of the brainstem  Enables non- verbal behavior & memory  Decision making  Coordinate voluntary movement and balance The Limbic System  Resides around the older brain parts and the cerebral hemispheres  Involved in emotion, memory, drives The Limbic System  Hippocampus: processes memory  Amygdala: influences aggression and fear  Perception of these emotions  Processing of emotional memories  Hypothalamus: monitors the pituitary gland  Influences feelings of hunger, thirst, body temperature and sexual arousal  Houses the pleasure or reward centers The Cerebral Cortex: our resource for adaptability  Largest part of the brain  Cerebral cortex  Cerebral hemispheres  Corpus callosum  Body’s ultimate control and information processing system  Adaptation of species resulted in changes in the cerebral cortex 15 Structure of the Cerebral Cortex  Frontal Lobes: Thinking, planning, movement  Parietal Lobes: body sensation  Occipital Lobes: Vision  Temporal Lobes: Hearing, language Functions of the Cerebral Cortex Functions of the Cerebral Cortex  Motor Functions  Message send out to the body is controlled by the motor cortex – the area at the rear of the frontal lobes  Sensory Functions  Incoming messages are controlled by the sensory cortex - area at the front of the parietal lobes  The rest (90% of the cortex): Association areas  Integrate information  Involved in higher mental functions such as language, remembering, thinking. Our divided brain  Hemispheres control and receive information from the opposite sides of the body  Hemispheric Specialization   Left hemisphere: language, logic, and complex motor behavior  Right hemisphere: non-linguistic functions including recognition of faces, places, and sounds (music) Localizing cognitive activities  Are abilities asymmetrically represented in the two hemispheres?  Left Hemisphere (LH) hemisphere critical for language  the idea of hemispheric specialization by the end of 1860s  hemispheric specialization : : the tendency for a given psychological function to be served by one of the hemispheres  evidence: LH lesions disrupt damage language; RH damage disrupt visual-spatial abilities  language faculty served by the LH; musical and visual-spatial cognition by the RH Language areas of the brain Split-Brain research  removal of corpus callosum, the connective tissue that communicates info between the LH and the RH, from epilectic patients  background: lateralization of visual, auditory, and tactile systems  one side of the brain controls the opposite of the body and information receiving field  set up a task that poses a question to one hemisphere and requires the answer from another Split brain: visual field study HE ART Left visual field Right visual field Interpretation of split-brain work  the RH of a split-brain patient has some awareness of the stimulus when a stimulus is presented to the left visual field  but cannot perform tasks where language skills are required  Hemispheric specialization/lateralization: the RH has a limited ability to perform language skills The brain acts as a unifed whole Ex: Language functions READING Register in visual area Transform words into auditory code Auditory code received and understood Motor area produces the word Brain Plasticity  The brain’s capacity for modification  Not only genes but also our expriences shape the brain  Brain reorganizes itself following damage (especially in children)  Many possibilities within the neural networks  Brain reorganizes itself through intense learning experiences  Blind people– use a finger to read Braille  Video--- woman born with half a brain
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            