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ANPS019 November 9, 2011 CEREBRUM Chapter 14: 486-476 THE CEREBRUM Is the largest part of the brain Controls all conscious thoughts and intellectual functions Processes somatic and visceral sensory and motor functions FUNCTIONAL PRINCIPLES OF THE CEREBRUM Each cerebral hemisphere receives sensory information from and sends motor commands to, the opposite side of the body Although their structures are similar, the 2 hemispheres have different functions e.g., language on left, face recognition of right) Specific regions of the cerebral cortex have specific functions, but there Is overlap Primary motor and sensory areas are organized into topographic maps representing specific body regions HEMISPHERIC LATERALIZATION Brain sided-ness does not always correspond to “handed-ness” Right side – “creative” Musical and artistic awareness Spatial and pattern perception Face recognition Emotional part of speech Left side- “analytical”: Spoken and written language Numerical and scientific skills Reasoning Everyone has the same pattern of gyri and sulci on their cerebral cortex -Different gyri deal with different types of information Sulces: shallow depressions Gyrus: elevated ridge Different areas of the cortex perform different functions “Primary” areas: neurons receive sensory information or directly send out motor instructions “Association” areas: neurons make sense of sensory information of plan motor activities (muscle movements) FRONTAL LOBE: MOTOR AND LIMBIC FUNCTIONS Central Sulcus: Separates frontal and parietal lobes -Primary Cortex -Premotor Cortex -Prefrontal Cortex Broca’s Ara (Motor Speech) Frontal Lobe: Primary Motor Cortex Primary Motor Cortex = Precentral gyrus -directs voluntary muscle movement -contains a map of all skeletal muscles -Pyramidal neurons (multipolar neurons that sends info down to body) in this gyrus that project via the internal capsule to synapse in the brainstem or spinal cord; they talk to the neurons that contact the muscles (they do NOT directly synapse on the muscles!!) Neurons in the primary motor cortex are arranged according to the muscles they control FRONTAL LOBE: PREMOTOR CORTEX *learned motor activities, planning of motor activities --people who this stroke: can execute motor activities, but can’t plan them out Directs neurons in the primary motor cortex; therefore less discrete topographic map Contains two specialized regions -frontal eye fields -Broca’s speech area: inability to product language FRONTAL LOBE: FRONTAL EYE FIELDS The purpose of this region is to keep the eyes directed forward. The right frontal eye field forces both eyes to the left while the left frontal eye field forces both eyes to the right. In a unilateral lesion, both eyes will deviate TOWARDS the side of the lesion. FRONTAL LOBE: BROCA’S SPEECH AREA Broca’s aphasia: motoraphasia -nothing wrong with moving tongue and lips Primarily located in left hemisphere – produces speech Expressive (motor, non-fluent) aphasia -anomia (inability to name objects) Patient aware of deficit FRONTAL LOBE: PREFRONTAL CORTEX LIMBIC Largest part of the frontal lobe Many connections to other areas Vague limbic functions (e.g., personality) PRIETAL LOBE: Somatosensation (the sense of touch, awareness of body) PARIETAL LOBE: PRIMARY SOMATOSENSORY CORTEX Primary somatosensory cortex = postcentral gyrus Receives somatic sensory information from skin receptors, joints and muscles: -touch, pressure, vibration -pain and temperature -taste Neurons in the primary somatosensory cortex are arranged according to the body region they receive information form PARIETAL LOBE: SOMATOSENSORY ASSOCATION CORTEX Interpretation of sensations Shape and texture of object Orientation of object (where an object is in space) Relationship of body parts -stroke to right parietal association cortex results in a fascination syndrome in which the patient disregards the left side of the body = syndrome of hemineglect TEMPORAL LOBE: HEARING, LIMBIC FUNCTION, VISUAL ASSOCIATION Primary auditory cortex Lateral fissure: separates frontal, parietal and temporal lobes Wernicke’s Speech Area TEMPORAL LOBE: PRIMARY AUDITORY COMPLEX Receives sounds information, sorts by frequency (tonotopic map) Pitch, rhythm Auditory Association: sorts sound into speech, music, tone (when song gets stuck in head0 TEMPORAL LOBE: WERNICKE’S SPEECH AREA Primarily located in left hemisphere Speech comprehension Receptive (sensory, fluent) aphasia -language comprehension affected -nonsensical speech, but patient unaware of deficit -anomia, impaired repetition, non-fluent reading -apraxia (inability to execute motor activity based on verbal command)