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Chapter 13 Central Nervous System 1 Mosby items and derived items © 2007, 2003 by Mosby, Inc. Coverings of the Brain and Spinal Cord  Two protective coverings:   Outer covering is bone Inner covering is the meninges  continues inside the spinal cavity beyond the end of the spinal cord 2 Coverings of the Brain and Spinal Cord  Meninges  3 membranous layers  Dura   mater strong, white fibrous tissue outer layer of meninges and inner periosteum of the cranial bones  Arachnoid  mater delicate, cobwebby layer between the dura mater and pia mater 3 Coverings of the Brain and Spinal Cord  Meninges  3 membranous layers (cont.)  Pia   mater innermost, transparent layer adheres to the outer surface of the brain and spinal cord 4 5 Cerebrospinal Fluid  Functions   Provides a supportive, protective cushion Reservoir of circulating fluid, which is monitored by the brain to detect changes in the internal environment  Fluid spaces  Cerebrospinal fluid— found around the brain and spinal cord 6 Cerebrospinal Fluid  Fluid spaces (cont.)  Ventricles— fluidfilled spaces within the brain; four ventricles within the brain 7 Spinal Cord  Structure of the spinal cord   Oval cylinder that tapers slightly from above downward Two bulges, one in the cervical region and one in the lumbar region 8 9 Spinal Cord  Structure of the spinal cord (cont.)  Nerve roots  Fibers  Carry sensory information into the spinal canal  Fibers   of dorsal nerve root of ventral nerve root Carry motor information out of the spinal cord Interneurons are located in the spinal cord’s gray matter core 10 Ventral (anterior) nerve root Dorsal (posterior) nerve root 11 Spinal Cord  Structure of the spinal cord (cont.)   Gray matter  Consists predominantly of cell bodies of interneurons and motor neurons  In transverse section, looks like an H White matter  Surrounds the gray matter  consists of a large bundle of axons divided into tracts 12 Spinal Cord  Functions of the spinal cord  Provides conduction routes to and from the brain  Ascending tracts (sensory)— conduct impulses up the cord to the brain  Descending tracts (motor)— conduct impulses down the cord from the brain  Bundles of axons compose all tracts 13 Spinal Cord  Functions of the spinal cord (cont.)  Important ascending (sensory) tracts = BLUE  crude touch, pain, and temperature  pressure  discriminating touch and conscious kinesthesia (proprioception)  subconscious kinesthesia  touch related to visual reflexes 14 Spinal Cord  Functions of the spinal cord (cont.)  Important descending (motor) tracts  voluntary movements on opposite side of the body  voluntary movements on same side of body  maintain posture during movement  transmit impulses that coordinate body movements and maintenance of posture  head and neck movements during visual reflexes  coordination of posture and balance  Spinal cord— reflex center for all spinal reflexes  reflex centers are located in the gray matter of the cord  15 16 The Brain  Structures of the brainstem  Medulla oblongata  Lowest part of the brainstem  Composed of white matter and a network of gray and white matter called the reticular formation  Nuclei— clusters of neuron cell bodies located in the reticular formation 17 The Brain  Structures of the brainstem (cont.)  Pons  Located above the medulla and below the midbrain  Composed  of white matter and reticular formation Midbrain  Located above the pons and below the cerebrum; forms the midsection of the brain  Composed  conduct  Red  of white tracts and reticular formation impulses between the midbrain and cerebrum nucleus and substantia nigra (“black matter”) clusters of cell bodies of neurons involved in muscular control 18 The Brain  Functions of the brainstem    Performs sensory, motor, and reflex functions Nuclei in medulla— contain reflex centers  Of primary importance— cardiac, vasomotor, and respiratory centers  Nonvital reflexes— vomiting, coughing, sneezing, etc. Pons— help regulate respiration 19 The Brain  Structure of the cerebellum   Gray matter makes up the cortex, and white matter predominates in the interior Cerebellum has numerous sulci (groove) and delicate, gyri (raised areas) 20 The Brain  Functions of the cerebellum   coordinates movements to produce the intended action General functions  produce skilled movements by coordinating the activities of muscles  maintains balance  Controls posture  smooth movements and make movements efficient and coordinated  Processes sensory information 21 Stand Up! 22 The Brain  Diencephalon  Located between the cerebrum and the midbrain  Consists of several structures: thalamus, hypothalamus, pineal gland, and several others  Thalamus  Dumbbell-shaped mass of gray matter made up of many nuclei  plays role in processing auditory and visual input 23 24 The Brain  Thalamus (cont.)  Serves as a major relay station for sensory impulses on their way to the cerebral cortex  Performs the following primary functions:    Two parts for sensations:  conscious recognition of the crude, less critical sensations of pain, temperature, and touch  Neurons relay all kinds of sensory impulses, except possibly olfactory, to the cerebrum emotions by associating sensory impulses with feeling of pleasantness and unpleasantness arousal mechanism 25 The Brain  Diencephalon (cont.)  Hypothalamus  lies beneath (hypo) the thalamus  Small but functionally important area of the brain, performs many functions of greatest importance for survival and enjoyment  Links mind and body  Links nervous system to endocrine system 26 The Brain  Hypothalamus (cont.)  Summary        of hypothalamic functions Regulator and coordinator of autonomic activities Major relay station between the cerebral cortex and lower autonomic centers crucial part of the route by which emotions can express themselves in changed bodily functions maintaining water balance arousal mechanism regulating appetite maintaining normal body temperature 27 The Brain  Diencephalon (cont.)  Pineal gland  Involved in regulating the body’s biological clock  Produces melatonin as a “timekeeping hormone”    Melatonin is made from the neurotransmitter serotonin Melatonin levels increase when sunlight is absent and decreases when sunlight is present, thus regulating the circadian (daily) biological clock (Figure 13-15) Melatonin is the “sleep hormone” 28 29 The Brain  Structure of the cerebrum  Cerebral cortex  Largest and uppermost division of the brain  consists of right and left cerebral hemispheres  each hemisphere is divided into four lobes:     Frontal lobe Parietal lobe Temporal lobe Occipital lobe 30 31 The Brain  Cerebral cortex (cont.)  Cerebral cortex— outer surface made up of six layers of gray matter  Gyri— raised areas  Sulci— shallow grooves 32 The Brain  Cerebral cortex (cont.)  Fissures— deeper grooves, divide each cerebral hemisphere into lobes   Central sulcus— groove between frontal and parietal lobes Lateral fissure— groove between temporal lobe below and parietal lobes above 33 Structure of the cerebrum Basal nuclei (or cerebral nuclei)  Basal nuclei— islands of gray matter located deep inside the white matter of each hemisphere  Unsure of exact function but important in regulating voluntary motor functions, especially repetitive actions  Example: maintaining posture, walking 34 The Brain  Functions of the cerebral cortex  Certain areas of cortex have certain functions  Transverse gyrus— auditory area  Occipital lobe— visual areas  Precentral gyrussomatic motor  Postcentral gyrussomatic sensory 35 The Brain  Functions of the cerebral cortex (cont.)  Sensory functions of the cortex  Cortex contains a “somatic sensory map” of the body  Senses send information to primary sensory areas, as well as to other parts of the brain 36 The Brain  Motor functions of the cortex  For normal movements to occur, many parts of the nervous system must function  Precentral gyrus  primary somatic motor area  controls individual muscles  Secondary motor area (premotor)  in the gyrus immediately anterior to the precentral gyrus  activates groups of muscles simultaneously 37 The Brain  Integrative functions of the cortex  Consciousness  State of awareness of one’s self, one’s environment, and other beings  Depends on excitation of neurons from the reticular formation  Two about reticular activating system:  Functions as the alert system for the cerebral cortex  Its functioning is crucial for maintaining consciousness 38 The Brain  Integrative functions of the cortex (cont)  Language  Ability to speak and write words AND ability to understand spoken and written words  Left cerebral hemisphere contains speech centers in approximately 90% of the population  FYI: Explains Broca’s and Wernicke’s area 39 The Brain  Integrative functions of the cortex (cont.)  Emotions  Limbic system— also known as the “emotional brain”  hippocampus  Have primary connections with other parts of the brain, such as thalamus, amygdaloid nucleus, and hypothalamus  FYI: removal of hippocampus causes inability to recall new info 40 The Brain  Integrative functions of the cortex (cont)  Memory  One of the major human mental activities  Cortex is capable of storing and retrieving both short- and long-term memory  Temporal, parietal, and occipital lobes are among the areas responsible for short- and long-term memory  Cerebrum’s limbic system plays a key role in memory 41 The Brain  Right and left hemispheres of the cerebrum specialize in different functions  Both sides communicate with each other to accomplish complex functions  Left hemisphere is responsible for:  Language functions  Dominating control of certain hand movements  Right hemisphere is responsible for:  Auditory  Tactual perception  Perceiving and visualizing spatial relationships 42 Cycle of Life: Central Nervous System  The development and degeneration of the CNS is the most obvious functional change over the life span  Development of the brain and spinal cord begins in the womb  Lack of development in the newborn is evidenced by lack of:  Language- both speech and reading  Comprehension of spatial relationships  Complex motor skills- walking 43 Cycle of Life: Central Nervous System  Complex functions develop by adulthood  Late adulthood— tissues degenerate   Profound degeneration— unable to perform complex functions Milder degeneration— temporary memory lapse or difficulty with complex motor tasks 44 The Big Picture: The Central Nervous System and the Whole Body  Central nervous system ultimate regulator of the body  essential to survival  Able to integrate bits of information from all over the body, make sense of them, and make decisions  45