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Neurophysiology of the central nervous system Dr. Loai Alzghoul [email protected] Organization of the nervous system Organization of the nervous system Levels of the CNS 1) Spinal cord 2) Brain stem and sub cortical 3) Cerebral cortex 3 Major Levels of CNS Function • The spinal cord level. – more than just a conduit for signals from periphery of body to brain and vice versa. – cord contains: • walking circuits. • reflexes circuits. The brain stem and subcortical • Contains: – medulla, pons, mesencephalon, hypothalamus, thalamus, cerebellum and basal ganglia. • Controls subconscious body activities: – arterial pressure, respiration, equilibrium, feeding reflexes, emotional patterns. The Higher Brain or Cortical Level • Higher order functions : language, thoughts and personality • Large memory storehouse. • Each portion of the nervous system performs specific functions, but it is the cortex that opens the world up for one’s mind. Organization of the Nervous System • Sensory Division – tactile, visual, auditory, olfactory. • Motor Division – respond to and move about in our environment. • Integrative Division – process information, creation of memory. Somatosensory Axis of the Nervous System Figure 45-2 Skeletal Motor Nerve Axis of the Nervous System Figure 45-3 Terminology: Afferent VS Efferent Terminology: 1st order , 2nd order and 3rd order neurons Histology of the NS Neuron Structure Types of neurons Neuroglia Neuroglia Myelination Neuroglia Form the bloodcerebrospinal fluid barrier Neuroglia Neuroglia Phagocytize Neuroglia 1) Support for neurons Astrocytes 2) Form the blood –brain barrier 3) Maintain the prober environment for the neurons Astrocytes Astrocytes