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Human body in context 1 Unit 1: The nervous system and the brain. Introduction ............................................................................................................................................... 3 1. The nervous system ............................................................................................................................... 5 Activity 1. Click on the brain!(*)....... ............. ............. ............................ ............. ................................... 7 Activity 2. Become an assistant doctor(**) ............................................................................................... 7 Activity 3. Decide the damage and show it in the brain picture. Explain the symptoms to your partner. (*) ....... 8 2. Nerve cells: the neurons .......................................................................................................................... 9 3. Nerves ................................................................................................................................................ 10 Activity 4. Using the words below write a paragraph about what you didn‟t know about the nervous system and what you have just learned (*) ................................................................................................................ 11 Activity 5. Explain to your partner what you have learnt about the nervous system(**) ............................... 11 Activity 6. Now listen to your partner‟s explanation in English and complete this chart (**) ............................ 11 4. The Nerve Impulse ............................................................................................................................... 12 Activity 7. Reading comprehension. Analysing action and resting potential (***) .......................................... 15 Activity 8. Challenge your senses(*) Click on .............................................................................. 16 5. The role of myelin ................................................................................................................................. 16 Activity 9. Use the drawing to explain the role of myelin. (*) ...................................................................... 18 Activity 10. Draw a diagram relating nerve impulse and myelin. Draw a poster relating receptors, centres and effectors. Explain your diagram and poster to a partner(**). ...................................................................... 19 Activity 11. Now listen to your partner‟s explanation and complete this chart(**) ......................................... 19 Activity 12. Match each drawing with the speed you think an impulse travels through the neuron(***). ........... 20 6. The threshold. Effectors and receptors. .................................................................................................. 21 7. The Synapse........................................................................................................................................ 22 8. The reflex arc ....................................................................................................................................... 22 Activity 13. Build up a vocabulary with compound scientific words(*) .......................................................... 23 M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 2 Unit 1: The nervous system and the brain. Activity 14. Make groups of four. In pairs choose either the synapse or the reflex arc(**) ............................ 24 Activity 15. Reflexes (**) ........................................................................................................................ 25 Activity 16. Neuron speed (***) ............................................................................................................... 26 9. The Central Nervous System :The Spinal Cord........................................................................................ 28 Activity 17. Matching and classifying(**) .................................................................................................. 29 Activity 18. Relating and explaining(*) ..................................................................................................... 30 10. The Brain .......................................................................................................................................... 32 11. The Cerebrum. The Cerebral Cortex. .................................................................................................... 33 12. Association centres ............................................................................................................................. 34 Activity 19. Word bank, wordsearch and crossword(**) ............................................................................. 35 Activity 20. Nervous coordination(* and **) .............................................................................................. 38 13. Brain waves. Sleep. Memory................................................................................................................ 39 Activity 21. Go to sleep! (*) .................................................................................................................... 40 Activity 22. Alzheimer‟s disease. Click and learn about the unhealthy brain. (***) ................................ 42 14. Innate behaviour and learning .............................................................................................................. 44 Activity 23. Describe the functions of the cerebrum, cerebellum and medulla oblongata in the ..................... 45 brain. Use the words from this list(*) ....................................................................................................... 45 15. Voluntary actions ................................................................................................................................ 46 Activity 24. Compare the neurons in the diagram and explain the effect of drugs on a drug addict.(**) .......... 47 Activity 25. Discover your brain. Find the website and do the activity(**) ........................................... 48 Activity 26. Sex differences. Find the website and do the activity(**)..………………………………… .....49 Activity 27. Sheep brain dissection: the anatomy of memory (***)………………………………………….50 M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 3 Unit 1: The nervous system and the brain. Introduction Tell your partners five things your nervous system allows you to do. Write down the different answers from your classmates. Make a list with the things your brain does consciously and those it does unconsciously. Compare and contrast your list with a partner. Are there any actions your brain does you weren’t aware of? M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context M.Àngels Hernández Sierra 4 Unit 1: The nervous system and the brain. IES Valldemossa 2008 Human body in context 5 Unit 1: The nervous system and the brain. 1. The nervous system Click on Click on http://www.zimmertwins.ca/node/617589 http://kidshealth.org/kid/body/brain_noSW.html Whatch the clip called Brainstorm Roll over and find out the correct pronunciation. Communication is vital to survival. Specialized cells Build up a scientific vocabulary with all the words in allow messages to be carried from one cell to italics. Translate them into Catalan (and Spanish). another. In humans these cells make up the nervous system. The nervous system controls and coordinates Example: nervous system = cat. sistema nerviós sistema nervioso) all the essential functions of human body. The nervous system receives information and responds to internal and external changes M.Àngels Hernández Sierra IES Valldemossa 2008 (cast. Human body in context Activity 1. 6 Unit 1: The nervous system and the brain. Click on the brain!(*) http://www.nationalgeographic.com/guides/science/humanbody/brain.html#/intro/ 1.1. Go to this page and click on Stimulate the brain. Copy the part of the brain that reponds to the different stimuli in the drawing given below. Use different colours for the different parts (*) M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 7 Unit 1: The nervous system and the brain. Activity 2. Become an assistant doctor(**) 1.1. The drawing shows what various parts of the brain do (speech parla habla, balance equilibri equilibrio) 2.2. A scan shows the amount (quantitat cantidad) of electrical activity in different parts of a brain. Pictures A–D show some scans of people. What do you think the people A–D were doing when the scans were done? A B C D M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 8 Unit 1: The nervous system and the brain. 2.3. Diagnose from the image The picture shows an MRI (ressonància magnètica resonancia magnética ) of someone with a brain tumour. Does this person have difficulty in speaking, walking, hearing? Explain your answer. Activity 3. Decide where the damage is and show it in the brain picture. Explain the symptoms to your partner. Use the sentences below (*) I think that the damage is in the .........area This person may have dificulty in ....... Because the cancer tumour is in the area of .............. this person might not be able to........ M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 9 Unit 1: The nervous system and the brain. 1. Nerve cells: the neurons Neuron The cells that carry messages throughout the nervous system are called neurons. Because the messages take the form of electric signals, they are known as impulses. Neurons can be classified into three types according to the directions in which these impulses move. Sensory neurons carry impulses from the sense organs to the brain and the spinal cord. Motor neurons carry impulses from the brain and spinal cord to muscles or glands. Interneurons ( connector neuron or association neuron) connect sensory and motor neurons and carry impulses between them. Although neurons come in all shapes and sizes, they have enough features in common. The largest part of the neuron is the cell body. Spreading out of the cell boby are short branched extensions M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 10 Unit 1: The nervous system and the brain. called dendrites. Dendrites carry impulses from the environment or from other neurons toward the cell body. The long fiber that carries impulses away from the cell body is called axon or nerve fibre. The axon ends in a series of small branches called axon terminals.Neurons may have dozens or even hundreds of dendrites but usually only one axon. 2. Nerves Nerves The cell bodies of the neurons are mostly located in the brain or in the spinal cord and it is the nerve fibres or axons which run in the nerves. A nerve is easily visible, white, tough and stringy and consists of hundreds of microscopic nerve fibres bundled together. Most nerves will contain a mixture of sensory and motor fibres. So a nerve can carry many different impulses. These impulses will travel in one direction in sensory fibres and in opposite direction in motor fibres. Some of the axons are very long. The nerve fibres to the foot have their cell bodies in the spinal cord and the fibres run inside the nerves, without a break, down to skin of the toes or the muscles of the foot. Thus a single nerve cell may have a fibre about 1 metre long. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 11 Unit 1: The nervous system and the brain. Activity 4. Using the words below write a paragrahph about what you didn’t know about the nervous system and what you have just learned (*) Before I began to read about the nervous system I thought that… First of all… I found out that… I have learnt several interesting facts that help me As I read more ……….. I found out that… Additionally… Following this… Consequently… Activity 5. Explain to your partner using your paragraph what you have learnt so far about the nervous system(**) Activity 6. Now listen to your partner’s explanation in English and complete this chart (**) YES/NO Identifies main nervous system parts Introduces new scientific words Speaks clearly Expresses his/her ideas using English words Links information Uses English connectors to link information M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 12 Unit 1: The nervous system and the brain. 3. The Nerve Impulse Neurons net The nervous tissue displays electrical activity. This electrical activity is in the form of a nerve impulse, which is a flow of electrical charges along the cell membrane. This flow is due to movement of ions across the membrane. A nerve cell has an electrical potential or voltage across its cell membrane because of a difference in the number of possitively and negatively charged ions on each side of the cell membrane. This charge difference is known as the resting potential of the neuron‟s cell membrane. This potential is approximately 70 millivolts (mV). One millivolt is equal to 0.001 volt ( the potential between the poles of a flashlight battery is 1500 millivolts, or 1.5 volts). A nerve impulse causes a movements of ions across the cell membrane of a neuron. The inside of the neuron becomes more positive than the outside. The membrane is now said to be depolarized. As the impulse passes the inside of the neuron becomes again negative. The neuron‟s membrane is now said to be repolarized, which means that it is once again negatively charged on the inside and positively charged on the outside of the cell membrane. The depolarization and repolarization of a membrane produce an action potential. The nerve impulse can be defined as an action potential travelling along the membrane. There are several important facts about impulses (action potentials) that you should keep in mind. First, an impulse is not an electric current. Instead, it is a wave of depolarization and repolarization that passes along the neuron. When there is no impulse in a neuron + it is „resting‟. In this state, the ion pumps push three sodium ions (Na ) out of the neuron for each two M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 13 Unit 1: The nervous system and the brain. + potassium ions (K ) they let in. In addition to this, there are negatively charged proteins inside the neuron that cannot get out. This means that the inside of the neuron ends up being negatively charged compared with the outside. Remember the inside of the neuron is usually about –70 mV (millivolts) compared with the outside. If the negative charge inside the neuron changes from –70 mV to about –30 mV, an impulse is generated. This rising of the charge is usually caused by receptor molecules in a synapse. When the rise in charge occurs, the sodium channels open and sodium ions rush into the neuron (positive and negative charges attract). M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 14 Unit 1: The nervous system and the brain. Second, an impulse is much slower than an electric current. Electric current move almost instantaneously, whereas action potentials usually travel at speeds ranging from 10 centimetres per second to 1 metre per second. Third, unlike an electric current, the strength of an impulse is always the same- there is either an impulse in response to a stimulus or there is not. The impulse is selfpropagating, that is , an impulse at any point on the membrane causes an impulse to the next point along the membrane, but it can move only in one direction. The impulse is said to be unidirectional. The nerve fibres do not carry sensations like pain or cold. These sensations are felt only when a nerve impulse reaches the brain. All nerve impulses are similar; there is no difference between nerve impulses from the eyes, ears or hands. We are able to tell where the sensory impulses have come from and what caused them only because the impulses are sent to differents parts of the brain. The nerves from the eye go to the part of the brain concerned with sight. So when impulses are received in this area, the brain recognizes that they have come from the eyes and we “see” something. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 15 Unit 1: The nervous system and the brain. Activity 7. Reading comprehension. Analysing action and resting potential (***) 1 State (anomena nombra) two reasons why the inside of a resting axon is negatively charged compared with the outside. + 2 Why do Na ions enter the neuron when the sodium channels open? ………………………………………………………………………………………………………………… …………………………………………….. 3 What happens to the charge inside the axon when repolarisation occurs? …………………………………………….. 4 This graph shows an action potential. 4.1. What is happening to the ion pump (bomba bomba) and ion channels at points A–E? ……………………………………………………………………………………………………………… …………………………………………………. 4.2. How long does depolarisation take (quant dura cuanto dura)?…………………………………….. 4.3. What are the names of the processes shown by W, X, Y and Z? W ……………………………………………………….. X ………………………………………………………. Y ……………………………………………………….. Z ……………………………………………………….. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context Activity 8. 16 Unit 1: The nervous system and the brain. Challenge your senses(*) Click on http://www.bbc.co.uk/science/humanbody/body/interactives/senseschallenge/ Do the test and record the results. Compare your score with that of your partner. Rank the score of the whole class. Are there any significant gender differences (per gèneres por géneros)? 5. The role of myelin The impulse can move along the membrane as fast as 1 metre per second, but this is not practical for large animals. For example, a giraffe might have to wait three or four seconds for impulses to travel from its feet to its brain. Such delays would make large animals hopelessly uncoordinated. But as you probably know this is not the case. What improves the rate of impulses along an axon? The answer is a substance known as myelin. Myelin, which is composed 80 % lipid and 20 % protein, forms an insulated sheath, or wrapping, around the axon. The most important feature of myelin is that there are small nodes, or gaps, between adjacent sheaths along the axon. As an impulse moves down a myelinated (covered with myelin) axon, the impulse jumps from node to node instead of moving continuously along the membrane. This jumping greatly increases the speed of the impulse. Some large myelinated axons conduct impulses as rapidly as 200 metres per second. Because of myelin, the propagation of the nerve impulse is faster in vertebrates than in invertebrates. M.Àngels Hernández Sierra IES Valldemossa 2008 17 Human body in context Unit 1: The nervous system and the brain. English Català Castellano Sheath beina vaina Strengh força fuerza Threshold llindar umbral M.Àngels Hernández Sierra IES Valldemossa 2008 18 Human body in context Unit 1: The nervous system and the brain. Activity 9. Use the drawing to explain the role of myelin. Complete the explanation and the drawing with Ranvier node , sheath and Schawnn cell (*) 9.2 Complete the drawing, and label the following: axon axon terminal cell body cytoplasm dendrite myelin Schwann cell 9.3. What sort of neuron is this?………………………………………………………………… 9.4 What does this sort of neuron do? ………………………………………………………… 9.5 Mark on your diagram the direction an impulse travels. 9.6 Write two adaptations a neuron has to carry out (dur a terme llevar a cabo) its job (function). - M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 19 Unit 1: The nervous system and the brain. - 9.7 What changes would you make to your drawing to show a neuron that carries impulses more slowly than the one you have drawn?………………………………………………………………. ………………………………………………… 9.8 State two functions of myelin - - Activity 10. Draw a diagram relating nerve impulse and myelin. Draw a poster relating receptors, centres and effectors. Explain your diagram and poster to a partner(**). Activity 11. Now listen to your partner’s explanation and complete this chart(**) YES/NO The diagram is clear The poster clarifies the relationship between effectors and receptors Identifies points of difference and similarity between effectors and receptors Expresses his/her points using relevant units (millivolts, metres per second) Links nervous action to consequences (movement) Uses evidence to clarify points Introduces new vocabulary from the nervous sytem Identifies main features of the nerve impulse Introduces new vocabulary from the nervous sytem The visual aid (diagram/poster) supports the explanation M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 20 Unit 1: The nervous system and the brain. Activity 12. Match each drawing with the speed you think an impulse travels through the neuron or neurons shown. All the diagrams show the same distance. Briefly explain how you decided to match up the drawings and the speeds (***). M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 21 Unit 1: The nervous system and the brain. 6. The threshold. Effectors and receptors. Medulla oblongata Recall that the strength of an impulse is always the same-either there is an impulse in response to a stimulus or there is not. In other words, a stimulus must be of adequate strength to cause a neuron to conduct an impulse. The minimum level of a stimulus that is required to activate a neuron is called a threshold. Any stimulus that is weaker than the threshold will produce no impulse; any stimulus that is stronger than the threshold will produce an impulse. Thus a nerve impulse follows the all-or-none principle. It is important to mention that the all-or-none principle is not restricted to impulses as they travel along neurons. It also occurs when impulses move from one neuron to another and when information from the environment causes a nerve impulse to occur. Glands and muscles are called effectors because they go into action when they receive nerve impulses or hormones. The biceps is an effector which flexes the arm. The salivary gland is an effector which produces saliva when it receives a nerve impulse from the brain. The nerves also carry impulses back to the central nervous system from receptors in the sense organs of the body. These impulses from the eyes, ears, skin, etc make us aware of changes in our surroundings ans in ourselves. Nerve impulses back to the central nervous system are called sensory impulses; those from the central nervous system to the effectors, resulting in action of some kind, are called motor impulses. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 22 Unit 1: The nervous system and the brain. 7. The Synapse The axon ends with many small axon terminals. At these terminals the neuron may make contact with the dendrites of another neuron, with a receptor, or with an effector. Recall that receptors are special sensory neurons in sense organs that receive stimuli from the external environment. Effectors are muscles or glands that bring about coordinated response. An impulse from the finger tips has to pass through at least three neurons before reaching the brain and so produce a conscious sensation. The regions where impulses are able to cross from one neuron to the next are called synapses. The axon terminals at a synapse contain tiny vesicles, or sacs. These tiny vesicles are filled with chemicals known as neurotransmitters. A neurotransmitter is used by one neuron to signal another. When an impulse arrives at a synapse, it releases a tiny amount of neurotransmitter which sets off an impulse in the next neuron. 8. The reflex arc One of the simplest situations where impulses cross synapses to produce action is the reflex arc. A reflex action is an automatic response to a stimulus. When a particle of dust touches the cornea of the eye, you will blink; you cannot prevent yourself from blinking. A particle of food touching the lining of the windpipe will set off a coughing reflex which cannot be suppressed. When a bright light shines in the eye, the pupil contracts. You cannot stop this reflex and you are not even aware that it is happening. The nervous pathway for such reflexes is called a reflex arc. The nervous pathway for the “knee-jerk” reflex is well-known. M.Àngels Hernández Sierra IES Valldemossa 2008 23 Human body in context Unit 1: The nervous system and the brain. Knee jerk One leg is crossed over the other and the muscles are totally relaxed. If the tendon just below the kneecap of the upper leg is tapped sharply, a reflex arc makes the tigh muscle contract and the lower part of the leg swings forward. Hitting the tendon stretches the muscle and stimulates a strech receptor. The receptor sends off impulses in a sensory fibre. These sensory impulses travel in the nerve to the spinal cord. Activity 13. Build up a vocabulary with compound scientific words(*) Example knee-jerk (action) reflex rotulià reflejo rotuliano kneecap (anatomy part) M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 24 Unit 1: The nervous system and the brain. Flexor hand muscles In the central region of the spinal cord, the sensory fibre passes the impulse across a synapse to a motor neuron which conducts the impulse down the fibre, back to the thigh muscle. The arrival at the muscles makes it contract, and jerk the lower part of the limb forward. You are aware that this is happening ( which means that sensory impulses must be reaching the brain), but there is nothing you can do to stop it. Activity 14. Make groups of four. In pairs choose either the synapse or the reflex arc (each pair does a different one). Use these words to explain it as a process of cause and effect with a time sequence.(**) First..... This, in turn, causes….. Next......... Precipitating…….. Then......... Initiating….. After that........ The effect of this is…. Later.......... As a consequence… As a result…… Finally........ Consequently……. Record the key vocabulary with the scientific terminology used for both explanations. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 25 Unit 1: The nervous system and the brain. Activity 15. Reflexes (**) Drawing A shows the arrangement (disposició disposición) of neurons to and from the elbow. Drawing B shows the arrangement of neurons to and from the knee. 1. What are arrangements of neurons like these called? 2. All the neurons in these arrangements are myelinated. What does this mean? 3. How does myelination help these neurons to carry out their functions? Put ticks in the two correct boxes It insulates (aïlla aisla) neurons from each other. It speeds up (accelera acelera) impulses. It forms synapses with other neurons. It anchors (fixa fija) the neurons in their correct positions. 4. The passage of an impulse through this arrangement (grup grupo) can be shown on a diagram. Write the words from the list into the diagram empty boxes. 5. The distance travelled by impulses in each arrangement of neurons is about (més o menys más o menos) the same. In which drawing, the leg or the arm, will the passage (pas paso) of an impulse be faster? ........ 6. Give one reason for your answer to part 5. ……………………………………………………………………………………………………………… 7. What is the name for a neuron like the one labelled (etiquetada etiquetada) X in drawing A? .......................................................................... M.Àngels Hernández Sierra IES Valldemossa 2008 26 Human body in context Unit 1: The nervous system and the brain. Activity 16. Neuron speed (***) 1. Scientists calculated the speeds of impulses in different types of invertebrate neuron (A–E). They then measured the diameter of each type of neuron. The table shows their results. Name of neuron Diameter of axon (µm*) Impulse speed (m/s) A 14.0 25 B 18.5 42 C 2.5 0.5 D 11.0 17 E 3.0 4.2 * 1 micrometre (m) = 0.001 mm a In which neuron did impulses travel fastest?……………………………………………………………. b What did the scientists need to measure in order to calculate the speed?………………………………………………………………………………………………………. ……………………………………………………………………………………………………………… c Draw a graph to show how the impulse speed changes with increasing (en augment en aumento) diameter of the axon. Put the diameter on the horizontal axis. Use a separate paper. d What correlation does your graph show?……………………………………………………………… …………………………………………………………………………………………………………………. …………………………………………………………………………………………………………………. e Which neuron does not fit the pattern (no segueix el patró o model no sigue el patrón o modelo)?………………………………………………………………… f Suggest what may be the difference between this neuron and all the others……………………………................................................................................................. …………………………………………………………………………………………………………………. ……………………………………………………………………………………………………………… g If impulses travel through many neurons linked, they are slower than if they travel the same distance along a single neuron. Why? …………………………………………………………… ………………………………………………………………………………………………………………….. ………………………………………………………………………………………………………………….. 2. An impulse has to travel a total of 1.4 metres from a sensory neuron in a little toe, to a neuron in the spinal cord and finally to another neuron in the brain. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 27 Unit 1: The nervous system and the brain. The time for the impulse to cross each synapse is 0.5 milliseconds. The impulse travels at a mean speed of 100 m/s. How long does the impulse take? Write all the calculations here …………………………………………………………………………. ………………………………………………………………………………………………………………… ........................................................................................................................................................ .................................................................................................................................................................. 3. Explain how a neurotransmitter causes an impulse to cross a synapse by writing three sentences. Each sentence must contain the words shown below. Beware some words are not in the process order impulse, vesicles, neurotransmitter .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... synapse, released, gap .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... receptor, bond, impulse .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... .......................................................................................................................................................... M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 28 Unit 1: The nervous system and the brain. 9. The Central Nervous System :The Spinal Cord Spinal cord The spinal cord acts as a communications link between the brain and the rest of the nervous system. In addition to carrying impulses to and from the brain, the spinal cord regulates reflexes. A reflex is the simplest response to a stimulus. The spinal nerve divides into two “roots” at the point where it joins the spinal cord. All the sensory fibres enter through the dorsal root and the motor fibres leave through the ventral root, but both kinds of fibre are contained in the same spinal nerve. The cells bodies of all the sensory fibres are situated in the dorsal root and they make a bulge called ganglion. Sneezing and blinking are two examples of reflexes. The reflexe closure of the eye protects the retina from bright light; the sneezing reflex dislodges a foreign particle from the nose. Thus, these reflexes have a protective function.There are many other reflexes going on inside our bodies. We are usually unaware of these, but they maintain our blood pressure, breathing rate, heart beat, etc and so maintain the body processes. In a cross section of the spinal cord we can notice that it consists of two types of nerve tissue. The central portion of the cord is H-shaped and is made up of gray ( grey in UK) matter. Gray matter consists of nerve cells bodies and unmyelinated axons. The outer portion of the cord consists of white matter, which is made of myelinated axons. Sensory neurons carry impulses from receptors to the spinal cord, and motor neurons carry impulses from the spinal cord to the effectors. Within the spinal cord, motor and sensory neurons are connected by interneurons. M.Àngels Hernández Sierra IES Valldemossa 2008 29 Human body in context Unit 1: The nervous system and the brain. Activity 17. Matching and classifying(**) 1 Match the definition with a word from the list: brain, neurotransmitter, neuron, axon, impulse, nerves, synapse, dendrite, myelin, threshold. a. progressive wave of biochemically generated energy that travels along a nerve fibre or muscle and stimulates or inhibits activity b. a branched extension of a nerve cell neuron that receives electrical signals from other neurons and conducts those signals to the cell body c. a bundle of fibres forming a network that transmits messages in the form of impulses between the brain or spinal cord and the body's organs d. a material made up of protein and fats that surrounds some nerve cells in concentric layers, insulating adjacent nerve fibres and enabling transmission of nerve impulses e. the smallest detectable sensation f. a cell, usually consisting of a cell body, axon, and dendrites, that transmits nerve impulses and is the basic functional unit of the nervous system g. the controlling centre of the nervous system in vertebrates, connected to the spinal cord and enclosed in the cranium h. an extension of a nerve cell, similar in shape to a thread, that transmits impulses outwards from the cell body i. a junction between two nerve cells, where the tip of a nerve fibre almost touches another cell in order to transmit signals j. a chemical that carries messages between different nerve cells or between nerve cells and muscles 2 Classify the previous words into processes and anatomical parts. Compare your list with your partner. Example Processes Anatomical parts letter a letter b M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 30 Unit 1: The nervous system and the brain. Activity 18. Relating and explaining(*) 1. Complete the drawing with the number given to the word(s) in the box. Nucleus (1), cell body (2), dendrites (3), axon (4), myelin sheath (5), nerve impulse (6), direction of impulse (7), synapse (8), vesicle (9), neurotransmitters (10), axon terminals (11), dendrite of receiving neuron (12), receptor molecules (13) 2. Give a title to the previous drawing: ......................................................................................................... M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 31 Unit 1: The nervous system and the brain. 3. Are those drawings below processes or anatomical parts of the nervous system? : drawing A drawing B Explain to your partner the reasons for your choice. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 32 Unit 1: The nervous system and the brain. 10. The Brain Inferior brain The brain is the place to where impulses flow and from where impulses originate. The spinal cord provides the link between the brain and the rest of the body. In addition of being protected by a bony covering called the skull, the brain is also wrapped in three layers known as the meninges. The innermost layer is called the pia mater. The outermost layer is called dura mater. In between there is the arachnoid . Between the arachnoid and the pia mater is a space that is filled with the cerebrospinal fluid. The cerebrospinal fluid protects the brain from mechanical injury by acting as a shock absorber. In order for the brain to perform its functions, it must have a constant supply of food and oxygen. If the oxygen supply to the brain is cut off even for a few minutes, the brain will usually suffer enormous damage. Such damage may result in death. The spinal cord is continuous with the brain and emerges from the opening at the base of the skull. The spinal cord stretches downward for approximately 42 to 45 cm. Like the brain, the spinal cord is protected by bone ( vertebral column), by the meninges, and by cerebrospinal fluid. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 33 Unit 1: The nervous system and the brain. 11. The Cerebrum. The Cerebral Cortex. The cerebral cortex The largest and most prominent part of the human brain is the cerebrum.The cerebrum is responsible for all the voluntary ( concious) activities of the body. In addition, it is the site of intelligence, learning and judgment. The cerebrum is divided into two hemispheres. As a result of much research, scientists have discovered that the left side of the body sends its sensations to the right hemisphere of the cerebrum, and the right side of the body sends its sensations to the left side of the body. There is another remarkable aspect to the way in which the two hemispheres of the cerebrum function. The right hemisphere is associated with creativity and artistic ability, whereas the left hemisphere is associated with analytical and mathematical ability. The outer surface of the cerebrum is the cerebral cortex and consists of gray matter. Many of the functions that we associate with the brain are performed in the gray matter of the cerebral cortex. Some regions of the cerebral cortex are associated with sensory input; others, with motor output. Still other regions in the cerebral cortex are responsible for specific skills, such as the complex series of movements necessary for speech and the understanding of speech itself. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 34 Unit 1: The nervous system and the brain. For some time, scientists believed that many functions of the body were controlled by specific regions of the cerebral cortex. In recent years the story has turned out to be quite a bit more complex. You might think that sensory neurons are connected directly to the appropiate part of the sensory cortex. This is not the case. There is not direct connection. Instead, sensory neurons synapse in the spinal cord, and neurons located in the spinal cord carry the impulse to the sensory cortex of the cerebrum. 12. Association centres How does this brain differ from the one you saw at the beginning? Compare your answer with your partner’s one The cerebral cortex, and many other regions of the brain, function as association centres. In these centres. In these centres, sensory information from a variety of sources ( eyes, ears, muscles, skin, etc.) Is fed in. This information is correlated with data from the memory centres and a course of action ( or inaction ) is computed. Motor impulses are then sent to the brain centres concerned with action. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 35 Unit 1: The nervous system and the brain. Activity 19. Crossword, wordsearch and word bank (**) 1. Crossword Across:1. message that takes the form of electric signals 3. cell that carry messages throughout the nervous system 4. chemicals used by one neuron to signal another 8. region where impulses are able to cross from one neuron to the next Down: 2.minimum level of a stimulus that is required to activate a neuron 5. connect sensory and motor neurons and carry impulses between them 6. the largest part of the neuron 7. inside of the neuron becomes again negative 9. The inside of the neuron becomes more positive than the outside 10. short branched extensions from neurons M.Àngels Hernández Sierra IES Valldemossa 2008 36 Human body in context Unit 1: The nervous system and the brain. 2. Find 10 words connected with temperature control in the wordsearch, and write them on the lines below. Write a clue for each word. Q E M O I Q J J U V H H Y U H R K V E F F E C T O R S V G U Y I Z A X O T V F T F V K E T Y P V V P C M U S C L E I I C S I O N V O H K E C F B H V N A W F T W C R E C E P T O R E E P E R H T V A T A C F E E A A I I A R A N A T C L S M J H G I I L T W L T F E B K H A I R D E 4 N G T A R D J L A I D H N L V E L L J M Y G J V A V Q B C F E E A A E U O P R O C E S S I N G C E N T R E H N W K R A F H C A N A D H N S Word Clue ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ ___________________________ ______________________________________________________ M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 37 Unit 1: The nervous system and the brain. 3. Read the hidden message after finding 10 words related to the nervous system. The ten words are: ...................................................................................................................... ........................................................................................................................................................ ........................................................................................................................................................... The hidden message is: ............................................................................................................... .................................................................................................................................................................. M.Àngels Hernández Sierra IES Valldemossa 2008 38 Human body in context Unit 1: The nervous system and the brain. Activity 20. Nervous coordination(* and **) 1. Look at the sentences below and then fill in the table. a Iker sees in a TV guide that there is something good on TV and he switches the TV on with the remote control. b Anna turned the CD player off when she realised she was listening to one of her father‟s CDs. Sentence What is the stimulus? Where are the receptor cells for this stimulus? What is the response? Where are the effector cells for this response? a b 2. On the diagram: a name and label the two organs in Iker central nervous system b label two nerves in Iker peripheral nervous system. c draw a line (with an arrow) to show how the brain senses that you Iker has touched something with his finger. 3.Draw lines to connect the following cells to the drawing of the neuron they send impulses to or receive impulses from. a a cell in the retina of the eye b a muscle cell c an adrenal gland cell d a „touch receptor‟ in the skin (tacte tacto) M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 39 Unit 1: The nervous system and the brain. 13. Brain waves. Sleep. Memory Tell your partner about your sleeping habits. Do you change them during the week-end? Why do you think sleep is important? Sleep waves Because the brain contains so many neurons it is a source of electrical activity. When a recording of electrical activity is made, the result is a record called an electroencephalogram( EEG ) . M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 40 Unit 1: The nervous system and the brain. When the activity of the cerebral cortex falls to the lowest possible level, a person becomes unconscious. Forms of unconsciousness can range from a deep, unresponsive state to a light sleep. During deep sleep a group of neurons cause decline in heart rate, blood pressure, respiratory rate, and use of energy. During rapid eye movement ( REM) sleep, active dreaming occurs. In a computer, information is coded in numerical form and stored as bits in a special memory region of the circuit system. Is it the same in the brain? The answer is both yes and no. There are at least two kinds of memory : short-term ( primary) and long-term. Short term memory is not permanent and vanishes within a few days. Long term memories are more permanent and some may last for a lifetime. Longterm memories are stored in no particular place but in the structure of the brain itself. Activity 21. Go to sleep! (*) 21.1 Write the wave type (alpha or betha) that are shown in the picture above(*) wave a: M.Àngels Hernández Sierra wave b: IES Valldemossa 2008 Human body in context 21.2 41 Unit 1: The nervous system and the brain. Click on http://www.bbc.co.uk/science/humanbody/sleep/profiler/ Answer the sleep profiler test M.Àngels Hernández Sierra IES Valldemossa 2008 42 Human body in context Activity 22. Unit 1: The nervous system and the brain. Alzheimer’s disease. Click and learn about the unhealthy brain. (***) http://www.nationalgeographic.com/guides/science/humanbody/brain.html#/brainUnhealthy/ 22.1 Explain what Alzheimer‟s disease does to the brain as seen in the picture 22.2 Label the diagram to show which side shows a normal brain and which side shows a brain with Alzheimer‟s disease. 22.3 What causes Alzheimer‟s disease? Tick one box. drinking from aluminium cans old age drinking too many fizzy drinks nerves cells dying in the brain forgetting to do things The picture shows neurons from the brain of a healthy 75 year old (A), and from the brain of a 75 year old suffering from Alzheimer‟s disease (B). M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 43 Unit 1: The nervous system and the brain. 22.4 State two differences between the neurons A and B. ---. ..........................................................................................................................….............… -- ..........................................................................................................................….............… 22.5 Name the region of the brain from which the neurons in B might have come. ..............................................................................................................................….............… 22.6 Suggest three symptoms of Alzheimer‟s disease likely to arise from the appearance of the neurons in individual B. 22.6.1. ..........................................................................................................................….............… ..............................................................................................................................….............… 22.6.2. ..........................................................................................................................….............… ..............................................................................................................................….............… 22.6.3. ..........................................................................................................................….............… ..............................................................................................................................….............… 22.7. Describe what other changes may happen in the brain of a patient suffering from Alzheimer‟s disease. ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 44 Unit 1: The nervous system and the brain. 14. Innate behaviour and learning The cerebellum A chick will peck at objects on the ground when it sees its mother pecking. It does not have to learn this behaviour; it is born with the nerve circuits that produce this behaviour already connected. This is innate behaviour ( sometimes called instinct ) and it may involve a simple reflex such as pecking or a more complex one such as remaining motionless in response to the parent‟s warning cries. At first, the chick pecks indiscriminately at small objects on the ground. Some of these will taste unpleasant and the pecking reflex is modified to avoid these and select only palatable material. This is learned behaviour. The innate reflex has been modified, by trial and error and the chick has been conditioned by its experience. Learning behaviour may become very complex. In humans, learning may involve conditioned reflexes but it also involves laying down a memory store in the brain. Human learned behaviour depends largely on being able to drawn on the memory store either consciously or unconsciously. The ability to learn by conditioned reflex or by any other process has survival value. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 45 Unit 1: The nervous system and the brain. Activity 23. Describe the functions of the cerebrum, cerebellum and medulla oblongata in the brain. Use the words from this list(*) To begin with… It starts by/with…I want to describe… There are different functions … The location of………. To better understand…….. it is necessary to examine … There are several reasons for this, the first One function of… It is believed/understood that.. After that… Influenced by… So, now you can see… In conclusion the facts show Consequently… Finally… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… ..............................................................................................................................….............… M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 46 Unit 1: The nervous system and the brain. 15. Voluntary actions A voluntary action starts in the brain. It may be the result of external events, such as seeing a book on the floor, but any resulting action, such as picking up the book, is entirely voluntary. Unlike a reflex action it does not happen automatically, you can decide whether or not you carry out the action. The brain sends motor impulses down the spinal cord in the nerve fibres. These make synapses with motor fibres which enter spinal nerves and make connections to sets of muscles needed to produce effective action. Many sets of muscles in the arms, legs and trunk would be brought into play in order to pick up the book, and impulses passing between the eyes, brain and arm would direct the hand to the right place and “tell” the fingers when to close on the book. One of the main functions of the brain is to co-ordinate these actions so that they happen in the right time and place. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 47 Unit 1: The nervous system and the brain. Activity 24. Compare the neurons in the diagram and explain the effect of drugs such as crack and cocaine on a drug addict. Use some of the words and sentences below.(**) I want to explain why There are several reasons for this The first reason is, another reason is Now you can see why I want to explain how To being with, it And this means / changes to After that As a result of this The final result is that One explanation for this is The evidence for this is This explanation is based on Of the alternative explanations, I think the most likely is…. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context Activity 25. 48 Unit 1: The nervous system and the brain. Discover your brain. Find the website and do the activity(**) http://www.bbc.co.uk/science/humanbody/body/interactives/organs/brainmap/index.shtml Translate all the new words and add them to your vocabulary. What does the phrase fight or flight mean? Explain it to your partner using an everyday example M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context Activity 26. 49 Unit 1: The nervous system and the brain. Sex Differences in the Brain(**) There are many sex differences in the brain. Check out the website and find out if this is true. http://www.bbc.co.uk/science/humanbody/sex/add_user.shtml Men and women differ not only in their physical attributes and reproductive function but also in many other characteristics, including the way they solve intellectual problems. For the past few decades, it has been ideologically fashionable to insist that these behavioral differences are minimal and are the consequence of variations in experience during development before and after adolescence. Evidence accumulated more recently, however, suggests that the effects of sex hormones on brain organization occur so early in life that from the start the environment is acting on differently wired brains in boys and girls. M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context Activity 27. 50 Unit 1: The nervous system and the brain. Sheep brain dissection: the anatomy of memory http://www.exploratorium.edu/memory/braindissection/ Watch the videos and learn from the dissection where the memory is stored M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 51 Unit 1: The nervous system and the brain. BRAIN AWARENESS WEEK(*) March 10-16, 2008 http://www.sfn.org/index.cfm?pagename=publicResources&redirect=SubCategory.cfm&cat_id=1 Music Training and The Brain Advocates for music education have always sworn that piano lessons pay off. Although no one would have denied that music training makes you more wellrounded and may even help you liven up some holiday parties, the extent of its benefit was unclear. Now, an increasing amount of scientific research is indicating that the benefits of music training reach to the brain. Some studies are suggesting that it boosts brain circuitry and increases certain mental functions. Further insights into how music training affects the brain may lead to new education methods and new ways to treat brain damage Alcoholism Until recently, little could be done to help keep problem drinkers from consuming alcohol except for counseling programs, which can be costly and do not always work. Thanks, however, to discoveries on the chemistry of alcohol's effects, some biology-based treatments are now available and even more help is on the way. The research is leading to: an increased understanding of how various systems in the brain contribute to alcoholism and a wider range of treatment options for individuals with alcohol problems M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 52 Unit 1: The nervous system and the brain. Adult Neurogenesis For more than a century, medical science firmly believed that our brain could not repair itself and that we were born with all the brain cells we would ever have. That belief has changed. Over the last 20 years, research has shown that neurogenesis, the creation of new brain cells, actually occurs in the adult human. For decades, scientists believed that brain cells of the central nervous system could not regrow following damage due to trauma such as head injury or disorders such as Alzheimer's disease. Scientists recently have discovered a whole family of proteins called neurotrophic factors. These proteins play a crucial role in the development and survival of nerve cells, or neurons, and in supporting adult neurons to keep them healthy throughout life Child Abuse and the Brain There's no doubt that child abuse has serious consequences. The effects, however, may be even worse than you think. An increasing amount of research indicates that severe maltreatment at an early age can create an enduring negative influence on a child's developing brain. The findings highlight the seriousness of childhood abuse and may lead to increased prevention efforts as well as new approaches for treatment. Some research shows that maltreatment may affect brain anatomy. Research also finds that a memory area, the hippocampus, is smaller in adult survivors of abuse with PTSD. Although still under investigation, it's possible that experiencing maltreatment during youth harms overall brain development and helps spur the ailments that seem to be common in these individuals . M.Àngels Hernández Sierra IES Valldemossa 2008 Human body in context 53 Unit 1: The nervous system and the brain. . Violent Brains Clearly, many factors lead a person to commit a violent act. Researchers are now finding out how biology may enter into the equation. Accumulating studies on animals and humans, for one, suggest that certain brain regions may sometimes contribute to violent behavior. The research is providing new insights into the biology behind violence and may lead to new ways to control it. Love and the Brain The analysis of love has moved from the embrace of poets into the arms of science. A recent series of precise studies reveal some of the key brain areas and molecules involved in the ability to love and bond with others. This research creates a better understanding of how the brain controls love and bonding, which is critical for species survival. In addition, the work may help researchers find ways to treat disorders like autism that are characterized by deficits in social interaction. M.Àngels Hernández Sierra IES Valldemossa 2008