Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau
... Fig. 1h). It remains open if these tau containing particles are made exclusively of tau or contain other constituents such as proteins and lipids. Human tau species observed within primary neurons 2–5 days after exposure to rTg4510 brain extract were Alz50 positive (Fig. 1i, top) but negative for Th ...
... Fig. 1h). It remains open if these tau containing particles are made exclusively of tau or contain other constituents such as proteins and lipids. Human tau species observed within primary neurons 2–5 days after exposure to rTg4510 brain extract were Alz50 positive (Fig. 1i, top) but negative for Th ...
Architecture and distribution of human corneal nerves
... three patients (aged 18, 28 and 38 years) with advanced keratoconus who underwent deep anterior lamellar keratoplasty (DALK) using the big-bubble technique. The superficial (approximately 50e70% thickness) and deep lamellae were studied. It has been shown that while the central corneal nerves are alt ...
... three patients (aged 18, 28 and 38 years) with advanced keratoconus who underwent deep anterior lamellar keratoplasty (DALK) using the big-bubble technique. The superficial (approximately 50e70% thickness) and deep lamellae were studied. It has been shown that while the central corneal nerves are alt ...
A Critical Review of Secondary Neurodegeneration
... Another approach used to study accumulation of amyloid-β in non-invasive imaging studies is the Pittsburgh compound B (PiB). [11C]PiB (PiB is labelled with radioactive carbon 11) is injected intravenously and is then used in combination with positron emission tomography (PET) to detect cerebral amyl ...
... Another approach used to study accumulation of amyloid-β in non-invasive imaging studies is the Pittsburgh compound B (PiB). [11C]PiB (PiB is labelled with radioactive carbon 11) is injected intravenously and is then used in combination with positron emission tomography (PET) to detect cerebral amyl ...
32 - Open-mind.net
... The idea that dreaming is a simulation of the waking world is currently becoming a far more widely shared and accepted view among dream researchers. Several philosophers, psychologists, and neuroscientists have recently characterized dreaming in terms of virtual reality, immersive spatiotemporal sim ...
... The idea that dreaming is a simulation of the waking world is currently becoming a far more widely shared and accepted view among dream researchers. Several philosophers, psychologists, and neuroscientists have recently characterized dreaming in terms of virtual reality, immersive spatiotemporal sim ...
Document
... Whereas the Tau-2 antibody labeled a number of tangles and neuropil threads in the entorhinal cortex, BIN1 antibodies labeled profuse punctate structures and cell soma that had no resemblance to tangles (Figure C). At closer inspection, only weak BIN1 immunoreactivity was found associated with the c ...
... Whereas the Tau-2 antibody labeled a number of tangles and neuropil threads in the entorhinal cortex, BIN1 antibodies labeled profuse punctate structures and cell soma that had no resemblance to tangles (Figure C). At closer inspection, only weak BIN1 immunoreactivity was found associated with the c ...
Can Oxytocin function as an antidepressant?
... coincides with a depressed state. When the depression subsides HPA activity normalizes. HPA activity is already used as a tool in measuring depressions and relapse chances. The DEX/CRH test has proven to be a very solid indicator for relapse chances after anti-depressant treatment. In the DEX/CRH, d ...
... coincides with a depressed state. When the depression subsides HPA activity normalizes. HPA activity is already used as a tool in measuring depressions and relapse chances. The DEX/CRH test has proven to be a very solid indicator for relapse chances after anti-depressant treatment. In the DEX/CRH, d ...
More on the evolution of imitation
... Infant facial imitation is a behavior that assesses the link between observation and execution of motor actions. The empirical findings at first surprised psychologists. They showed that infants could imitate prior to the learning experiences, indicating an innate mapping between observation and exe ...
... Infant facial imitation is a behavior that assesses the link between observation and execution of motor actions. The empirical findings at first surprised psychologists. They showed that infants could imitate prior to the learning experiences, indicating an innate mapping between observation and exe ...
PDF of article - Janelia Research Campus
... The Drosophila brain is formed by an invariant set of lineages, each of which is derived from a unique neural stem cell (neuroblast) and forms a genetic and structural unit of the brain. The task of reconstructing brain circuitry at the level of individual neurons can be made significantly easier by ...
... The Drosophila brain is formed by an invariant set of lineages, each of which is derived from a unique neural stem cell (neuroblast) and forms a genetic and structural unit of the brain. The task of reconstructing brain circuitry at the level of individual neurons can be made significantly easier by ...
Complete Pattern of Ocular Dominance Columns in Human Primary
... from six subjects of European descent with a history of monocular visual loss. They were patients of one of the authors (J.C.H.). Each patient, or surviving next-of-kin, provided written permission for postmortem histological examination, following a protocol approved by an Institutional Review Boar ...
... from six subjects of European descent with a history of monocular visual loss. They were patients of one of the authors (J.C.H.). Each patient, or surviving next-of-kin, provided written permission for postmortem histological examination, following a protocol approved by an Institutional Review Boar ...
Connection Patterns Distinguish 3 Regions of Human Parietal Cortex
... area Opt, and some transitional opercular regions in the most ventral part of the IPL are also recognized. Distinct functional and anatomical regions, MIP and PE, occupy the medial bank of the IPS and the superior parietal lobule (SPL). The functional specializations of these regions have been inves ...
... area Opt, and some transitional opercular regions in the most ventral part of the IPL are also recognized. Distinct functional and anatomical regions, MIP and PE, occupy the medial bank of the IPS and the superior parietal lobule (SPL). The functional specializations of these regions have been inves ...
Where do mirror neurons come from?
... Associative learning is a form of learning that results from exposure to a relationship between two events. ‘Conditioning procedures’ arrange different types of relationship between events. Research examining the effects of conditioning procedures on animal behaviour has shown that associative learn ...
... Associative learning is a form of learning that results from exposure to a relationship between two events. ‘Conditioning procedures’ arrange different types of relationship between events. Research examining the effects of conditioning procedures on animal behaviour has shown that associative learn ...
Chapter 1
... • Mothers coaxed their infants from across the “cliff” to see they would crawl on the glass over the drop-off. • Problems with drawing a conclusion as to how early depth perception is present include the fact that very young infants can’t crawl – a requirement of the study. ©2005 McGraw-Hill Ryerson ...
... • Mothers coaxed their infants from across the “cliff” to see they would crawl on the glass over the drop-off. • Problems with drawing a conclusion as to how early depth perception is present include the fact that very young infants can’t crawl – a requirement of the study. ©2005 McGraw-Hill Ryerson ...
donepezil dose-dependently inhibits acetylcholinesterase activity in
... obtained at autopsy (mean age 64.8 ^ 3.6 years). The interval between death and autopsy was less than 4 h. The left half of the human brain was sliced coronally into approximately 1 cm slabs, which were fixed by immersion for 24–36 h in an ice-cold 0.1 M phosphate-buffered (pH 7.4) 4% paraformaldehy ...
... obtained at autopsy (mean age 64.8 ^ 3.6 years). The interval between death and autopsy was less than 4 h. The left half of the human brain was sliced coronally into approximately 1 cm slabs, which were fixed by immersion for 24–36 h in an ice-cold 0.1 M phosphate-buffered (pH 7.4) 4% paraformaldehy ...
Alpha-beta and Gamma Rhythms Subserve Feedback and
... J.M., Kennedy, H. and Fries, P. Neuron 89, January 20, 2016. http://dx.doi.org/10.1016/j.neuron.2015.12.018. ...
... J.M., Kennedy, H. and Fries, P. Neuron 89, January 20, 2016. http://dx.doi.org/10.1016/j.neuron.2015.12.018. ...
A computational model of action selection in the basal ganglia. I. A
... central nervous system. The overall activity level of the neural representation of a given action may determine its salience or propensity to be selected for execution, as proposed by Koechlin and Burnod (1996). Rather than dealing directly with the neural codes for each action, we propose that the ...
... central nervous system. The overall activity level of the neural representation of a given action may determine its salience or propensity to be selected for execution, as proposed by Koechlin and Burnod (1996). Rather than dealing directly with the neural codes for each action, we propose that the ...
Foundations of Physiological Psychology, 7e (Carlson)
... 23) A serious complication of physiological analyses of behavior is that A) behaviors have to be explained in terms of molecular events. B) different physiological mechanisms may produce identical behaviors. C) different behaviors may occur for the same reasons. D) physiologists are only able to off ...
... 23) A serious complication of physiological analyses of behavior is that A) behaviors have to be explained in terms of molecular events. B) different physiological mechanisms may produce identical behaviors. C) different behaviors may occur for the same reasons. D) physiologists are only able to off ...
α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form
... Neuronal nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels. A total of 11 nAChR subunits (α2–7, α9–10, and β2–4) have been cloned from mammalian neuronal tissue [1]. Of these, the α7 and α9 subunits can form homomeric receptors when expressed in heterologous express ...
... Neuronal nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels. A total of 11 nAChR subunits (α2–7, α9–10, and β2–4) have been cloned from mammalian neuronal tissue [1]. Of these, the α7 and α9 subunits can form homomeric receptors when expressed in heterologous express ...
and Reflective Learning Practices
... seek to reflect on their experiences of working with clients, not through critical cognitive reflection but by "sitting" with a feeling; While in session, they did not use critical reflection to process this non-cognitive way of knowing. In fact, all the social work practitioners in this study belie ...
... seek to reflect on their experiences of working with clients, not through critical cognitive reflection but by "sitting" with a feeling; While in session, they did not use critical reflection to process this non-cognitive way of knowing. In fact, all the social work practitioners in this study belie ...
Sample
... b) has received, in its dendrites, appropriate inputs from other neurons Correct. A neuron fires after the dendrites receive enough stimulation to trigger the cell body to generate an action potential. c) is unable to transmit information to another neuron d) has become more negative in charge Incor ...
... b) has received, in its dendrites, appropriate inputs from other neurons Correct. A neuron fires after the dendrites receive enough stimulation to trigger the cell body to generate an action potential. c) is unable to transmit information to another neuron d) has become more negative in charge Incor ...
Synesthetic personification
... average reaction times where the synesthetic gender of the letter-prime conflicted with the semantic gender of the face (i.e., on incongruent trials) compared with when synesthetic and semantic genders matched (i.e., on congruent trials) even though the grapheme primes were irrelevant to the task. T ...
... average reaction times where the synesthetic gender of the letter-prime conflicted with the semantic gender of the face (i.e., on incongruent trials) compared with when synesthetic and semantic genders matched (i.e., on congruent trials) even though the grapheme primes were irrelevant to the task. T ...
Orexinergic Input to Dopaminergic Neurons of the Human Ventral
... immunohistochemistry was used and orexinergic projections to the VTA and to DA neurons of the neighboring substantia nigra (SN) were analyzed comparatively in adult male humans and rats. Orexin B-immunoreactive (IR) axons apposed to tyrosine hydroxylase (TH)-IR DA and to non-DA neurons were scarce i ...
... immunohistochemistry was used and orexinergic projections to the VTA and to DA neurons of the neighboring substantia nigra (SN) were analyzed comparatively in adult male humans and rats. Orexin B-immunoreactive (IR) axons apposed to tyrosine hydroxylase (TH)-IR DA and to non-DA neurons were scarce i ...
Trehan,K. WHO IS NOT SLEEPING WITH WHOM WHAT`S
... have become so habitual that they are no longer worthy of comment. The need to find and then question the hidden assumptions, ideas and values behind a practice (deconstruct the discourse) is highlighted by Edwards, writing on adult education, …’practice’ is already informed by overt or covert discu ...
... have become so habitual that they are no longer worthy of comment. The need to find and then question the hidden assumptions, ideas and values behind a practice (deconstruct the discourse) is highlighted by Edwards, writing on adult education, …’practice’ is already informed by overt or covert discu ...
cross-sectional and longitudinal analyses
... effects of VGP include effects on verbal memory, some types of attention, sleep, learning and knowledge.2–4 Furthermore, in imaging studies, VGP was shown to cause substantial dopamine release in the dopaminergic system5 as well as addiction.6 Previous cross-sectional studies have revealed that chil ...
... effects of VGP include effects on verbal memory, some types of attention, sleep, learning and knowledge.2–4 Furthermore, in imaging studies, VGP was shown to cause substantial dopamine release in the dopaminergic system5 as well as addiction.6 Previous cross-sectional studies have revealed that chil ...
Descartes` Error: Emotion, Reason, and the Human Brain
... pensable for rationality. At their best, feelings point us in the proper direction, take us to the appropriate place in a decision-making space, where we may put the instruments of logic to good use. We are faced by uncertainty when we have to make a moral judgment, decide on the course of a persona ...
... pensable for rationality. At their best, feelings point us in the proper direction, take us to the appropriate place in a decision-making space, where we may put the instruments of logic to good use. We are faced by uncertainty when we have to make a moral judgment, decide on the course of a persona ...
Birds, primates, and spoken language origins: behavioral
... might be distributed. Why does the variance in a behavioral phenotype matter? It is important to determine the ways in which, for example, vocal learning is distributed since each possibility carries with it different implications for: (1) how spoken language is likely to have originated; (2) the ev ...
... might be distributed. Why does the variance in a behavioral phenotype matter? It is important to determine the ways in which, for example, vocal learning is distributed since each possibility carries with it different implications for: (1) how spoken language is likely to have originated; (2) the ev ...
Evolution of human intelligence
The evolution of human intelligence refers to a set of theories that attempt to explain how human intelligence has evolved and are closely tied to the evolution of the human brain and to the origin of language.The timeline of human evolution spans approximately 7 million years, from the separation of the Pan genus until the emergence of behavioral modernity by 50,000 years ago. The first 3 million years of this timeline concern Sahelanthropus, the following 2 million concern Australopithecus and the final 2 million span the history of actual human species in the Paleolithic era.Many traits of human intelligence, such as empathy, theory of mind, mourning, ritual, and the use of symbols and tools, are apparent in great apes although in less sophisticated forms than found in humans, such as Great ape language.