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Nervous System Organization PNS and CNS Chapters 8 and 9 • Peripheral Nervous System (PNS) – connects CNS to sensory receptors, muscles and glands • Central Nervous System (CNS) – control/integrating center – brain + spinal cord Peripheral Nervous System • Rapid Communication • Consists of: – 12 pairs cranial nerves – 31 pairs spinal nerves Peripheral Nervous System • Sensory (Afferent) – convey impulses from sensory receptors to CNS – Afferent (sensory) neurons • Motor (Efferent) Nerves • axons of many neurons bundled together • transmit signals between brain or spinal cord and other body regions Motor Component • Somatic Nervous System (Voluntary) – conduct impulses from CNS to skeletal muscles • Autonomic Nervous System (Involuntary) – convey impulses from CNS to smooth muscle, cardiac muscle and glands – convey impulses away from CNS to periphery – Efferent (motor) neurons 1 Somatic Nervous System Structure • Single motor neuron cell leading from the CNS directly to the muscle • Cell body of motor neurons located in CNS Autonomic Nervous System Structure • Two neurons involved in efferent pathway (CNS to effector) • 1rst (preganglionic) has cell body in CNS – synapses with 2nd in the autonomic ganglion • 2nd (postganglionic) sends signal from auton. gang. to the effector organ Sympathetic and Parasympathetic Divisions • Sympathetic (thoracolumnar) – dominates in stressful situations – prepares body for activity ('Fight or Flight’) – adrenergic effects (use norepinephrine) • Parasympathetic (craniosacral) – dominates during relaxed situations – precise control over the body – cholinergic effects (use acetylcholine) Central Nervous System • Control and integration • Consists of – brain – spinal cord Sympathetic vs. Parasympathetic Effects Organ Sympathetic Parasympathetic Heart increases HR decreases HR Blood vessels to visceral organs constrict dilate Blood vessels to heart + skeletal muscle dilate constrict Digestive tract decreases motility increases motility Spinal Cord • Links brain and PNS • Controls some involuntary functions • Protected by vertebral column • 31 pairs of spinal nerves – Sensory Component – Motor Component 2 Spinal Cord Structure Spinal Cord Structure • Dorsal Root = sensory – Dorsal root ganglion = afferent cell bodies • Ventral Root = motor – Roots join to form spinal nerve • Tracts of interneuron axons carry information between spinal nerves and brain • Ascending tracts – carry sensory information up to the brain • Interneurons – White Matter = axons (myelin) • found in outer layer • Descending tracts – carry response information from brain to motor neurons – Gray Matter = primarily cell bodies, dendrites • found in inner layer Spinal Reflexes • Spinal cord alone can respond to some stimuli • Reflex - simple, stereotyped response to a stimulus Brain • • • • 1011 (100 billion) neurons grey matter mostly on outside (cortex) four fluid-filled chambers (ventricles) composed of sections: – Prosencephalon (forebrain) • telencephalon (Cerebrum) • diencephalon (Hypothalamus and Thalamus) – Mesencephalon (midbrain) – Rhombencephalon (hindbrain) • metencephalon (cerebellum, pons) • myelencephalon (medulla oblongata) Telencephalon (Cerebrum) Cerebral Lobes • Largest part of brain – 80% total brain wt • Cerebral Hemispheres (L and R) – connected by corpus callosum • Surface = cerebral cortex – most of the grey matter of the cerebrum • Deep folds (sulci) in between convolutions (gyri) • Cortex divided into paired lobes – – – – – Parietal Frontal Temporal Occipital Insula • Each has distinctive functions 3 Parietal Lobes • Perception of somatesthetic senses (touch, pressure, heat, cold, pain) – Somatosensory cortex - postcentral gyrus of the central fissue • Understanding language and formulating words – Angular gyrus • Interpretation of textures and shapes Frontal Lobes • voluntary movement of skeletal muscle (motor cortex) • personality • higher intellectual processes – planning, decision making • verbal communication – Broca’s area- motor mechanisms for speech Temporal and Occipital Lobes Somatosensory Cortex • Receives info. from various parts of body • Each region receives info. from specific body area (somatotopic) • diff. parts of body are not equally represented – hands and face have larger areas dedicated to processing of information • receives info. from opposite side of body (decussation) Motor Cortex • Precentral gyrus of the central fissue • Controls voluntary movements of skeletal muscles • Somatotopic • More area dedicated to body regions movements requiring precise movements • Decussation Insula Lobe • Temporal Lobe – auditory cortex • perception and interpretation of auditory info – storage of auditory and visual experiences – Language comprehension (Wernicke’s area) • Occipital Lobe – processing of visual information – visual cortex • Located beneath frontal and temporal lobes • Functions – Memory – Sensory integration (pain) – Cardiopulmonary responses to stress • interpretation of visual images • motor activity of eyes • correlation of images with previous visual experiences 4 Internal Grey Matter Internal Grey Matter • limbic system • basal nuclei – control of voluntary movements • Inhibition activity for maintaining muscle tone • Maintaining purposeful motor activity while suppressing unwanted activity • Monitor/coordinate slow sustained contractions • Gulf war syndrome – degeneration of basal nuclei Diencephalon • Thalamus – accepts sensory info. and sends it to cortex. – Epithalamus - roof of third ventricle • choroid plexus - produces cerebrospinal fluid • pineal body - produces melatonin (reproduction, circadian rhythms) • Hypothalamus – motivational behavior • hunger, thirst, body temperature, – neural control of hormonal release form the pituitary gland Metencephalon • Pons – interface for four pairs of cranial nerves – control of respiration • Cerebellum – coordination of body movements, posture, balance – Damage = jerky movements, difficulty walking – Located around brainstem – Portions of cerebrum and diencephalon • Extensive collection with hypothalamus – Relatively little connection with cerebral cortex – basic survival behaviors (search for food, aggression, fear, sexuality) – Emotion – Goal-directed behavior (reward/punishment) – Memory – Perception of smell (olfactory cortex) Mesencephalon • Located btw diencephalon and pons – corpora quadrigemina, red nucleus, substantia nigra, cerebral peduncles • visual reflexes • auditory information relay • motor coordination – links cerebrum and cerebellum – Parkinson’s disease • degeneration of the substantia nigra • motivational (reward) behavior Myelencephalon • Medulla oblongata – control of basal survival functions – Cardiac Center • regulates HR and contractile force – Respiratory Center • regulates respiration – Vasomotor Center • controls blood vessel diameter and blood pressure 5 Reticular Formation • Interneurons in medulla, pons, midbrain, thalamus and hypothalamus • receives and integrates incoming sensory info. • relays sensory info. to the cerebral cortex – nonspecific arousal of cerebrum 6