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The Brain, Addiction, and the Adolescence reisch Psy.D. Family Therapist lkin, BA, CDP ance Abuse Counselor Presentation Topics: scence, and Addiction Basic brain structure Adolescent brain development Addiction: Definition and physiology Treatment access and assessment Early intervention How you can help RE AND FUNCTIONS aveats • New discoveries – research still in its infancy • Do NOT over-interpret or interpret too simplistically • Most research has been conducted on animals • Brain interactions are complex TRUCTURES • Frontal Lobe • Cerebellum • Parietal Lobe • Corpus Callosum • Temporal Lobe • Brain Stem • Occipital Lobe N OF THE LOBES • The different lobes of the brain work together • Each area makes contributions to certain functions, TURE & FUNCTION ntal Lobe • Seat of personality, judgment, reasoning, problem solving, and ration • Provides for logic and understanding of consequences • Governs impulsivity, aggression, ability to organize thoughts, and pla • Controls capacity for abstraction, attention, cognitive flexibility, and g • Undergoes significant changes during adolescence — not fully deve olb & Wishaw, 2009) TURE & FUNCTION ntal Lobe • The “prefrontal cortex” matures through experience • Prefrontal cortex is one of the last areas of the brain • Increased need for structure, mentoring, guidance b & Wishaw, 2009) TURE & FUNCTION poral Lobe • Contains the limbic-reward system (amygdala, hippocampus, nucleu • • Regulates emotions and motivations—particularly those related to Matures around ages 18-19 b & Wishaw, 2009) TURE & FUNCTION ain Stem • All nerve fibers pass through this area • Performs sensory, motor, and reflex functions • Contains vital nerve centers that control breathing, • Connects the brain with the body b & Wishaw, 2009) IN CIRCUITRY ● Neuron: specialized cell designed to transmit inform ● Each neuron consists of a cell body, axon, and dendrite ● Axon: an electricity-conducting fiber that carries info ● Dendrite: receives messages from other neurons ● Synapse: contact point where one neuron “commun olb & Wishaw, 2009) RAIN DEVELOPMENT RAIN DEVELOPMENT • Adolescence is a period of profound brain maturatio • We thought brain development was complete by ad • We now know maturation is not complete until abou RAIN DEVELOPMENT Maturation occurs from the back of the brain to the fro RAIN DEVELOPMENT Prefrontal cortex is NOT fully developed in adolescenc • Prefrontal cortex is responsible for higher levels of th -decision making -planning -organizing -coordinating RAIN DEVELOPMENT The amygdala • The emotional center • Amygdala and nucleus accumbens (limbic system within th • Adolescents tend to rely on it more than adults when proce RAIN DEVELOPMENT Adolescent brain Adult Brain TION AND PRUNING TION AND PRUNING • Brain-imaging research reveals continued pruning o • This means use it or lose it! What is practiced durin (Giedd et al., 1999; Keating, 2004; Sowell et al., 2002) TION AND PRUNING URONS • Neurons become more responsive to excitatory neu • Stress AND pleasure are experienced more intense • These changes likely play a role in the drive for nov 007; Spear, 2003) T RISKY BEHAVIOR T RISKY BEHAVIOR • Adolescents are more likely than older/younger indi • Recent research indicates that adolescents’ decisio in, Hussong & Beltran, 2009; Gardner & Steinberg, 2005; Chein et al., 2011) LYING ADOLESCENT BEHAVIOR ● Joint contribution of 2RISKY brain systems affect adolescent ● Incentive Processing System – involves ventral striatum (VS ● Cognitive Control System – involves lateral prefrontal cortex 08; Luna, Padmanabhan & O’Hearn, 2010) YING ADOLESCENT RISKY BEHAVIOR • Both systems undergo considerable modification durin • Dramatic remodeling of the incentive processing system • Cognitive Control System undergoes comparatively gra 2009; Asato, Terwilliger, Woo & Luna, 2010; Giedd, 2008) mean for adolescents? • Preference for physical activity • Less than optimal planning and judgment • More risky, impulsive behaviors • Minimal consideration of negative consequences • Misinterpretation of emotional cues • Easier for adolescents to become addicted to mood alte ADDICTION: DEFINITIONS AND PHYSIOLOGY s addiction? The American Society of Addiction Medicine (ASAM) defines addiction a “... a primary, chronic disease of brain reward, motivation, memory and he brain get addicted? Addiction occurs when repeated use of drugs changes how a person http://www.drugabuse.gov/publications/principles-adolescent-substance-use-disorder-treatment-research-based-guide/frequently-asked-questions/how-do-adolescents-become-addicted-to-drugs-which-fa gy of addiction Limbic-Reward System • Drugs of abuse activate the reward system in the limbic area of the b • Fool brain into thinking that they are necessary for survival • Desire to repeat drug using behavior is strong • Drugs of abuse can/do exert powerful control over behavior because pact of drug use • The brain has a hard time experiencing pleasu • Impairment in cognitive functioning • Impairment in judgement and self-control (NIDA, 2014) xperiencing they are more at risk to struggle k Factors Associations with drug using peers Prenatal exposure to drugs and alcohol Genetic vulnerability History of physical and/or sexual abuse or other forms of trauma| Learning disabilities or other deficits in executive functioning ork to balance or counteract risk factors, making it u -NIDA nselors, parents, or other adults look for? ance abuse or addiction: ● a change in peer group ● carelessness with grooming ● decline in academic performance ● missing classes or skipping school ● loss of interest in favorite activities ● changes in eating or sleeping habits ● deteriorating relationships with family members and friends nd Treatment access n assessment? scent get an assessment? ment for adolescents… -involves inclusion of family and peer group -integrates community systems such as school and at -emphasizes pro-social peer relationships (NIDA, 2012) sources This link is especially important because it will provide you with a list of all treatment agencies and the s This site includes treatment data and admission statistics. This document provides trends in adolescent substance abuse. This provides a list of treatment centers that accept public funding. This is the National Institute for Drug Abuse website. Here you can find free publications about drug abu erences Asato, M. R., Terwilliger, R., Woo, J., & Luna, B. (2010). White matter development in adolescen Berk, L. E. (2007). Development through the lifespan, fourth edition. New York: Allyn & Bacon. Casey, B. J., Getz, S., & Galvan, A. (2008). The adolescent brain. Developmental Review, 28(1 Chassin, L., Hussong, A., & Beltran, I. (2009). Adolescent substance use. In R. Lerner & L. Stei Chein, J., Albert, D., O’Brien, L., Uckert, K., & Steinberg, L. (2011). Peers increase adolescent r Garner, M., & Steinberg, L. (2005). Peer influence on risk taking, risk preference, and risky deci erences Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., & Zijdenbos, A. (1999). B Giedd, J. N. (2008). The teen brain: insights from neuroimaging. Journal of Adolescent Health, 4 Keating, D. P., (2004). Cognitive and brain development. In R. M. Lerner & L. Steinberg (Eds.), Kolb, B., & Wishaw, I. Q. (2009). Fundamentals of human neuropsychology, sixth edition. New York: Worth. Laviola, G., Pascucci, T., & Pieretti, S. (2001). Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. Pharma Luna, B., Padmanabhan, A., & O’Hearn, K. (2010). What has fMRI told us about the development of cognitive control through adolescence? Br erences Simons-Morton, B., Lerner, N., & Singer, J. (2005). The observed effects of teenage passengers Sowel, E. R., Trauner, D. A., Gamst, A., & Jernigan, T. (2002). Development of cortical and subc Spear, L. P. (2003). Neurodevelopment during adolescence. In D. Cicchetti & E. Walker (Eds.), Spear, L. (2009). The behavioral neuroscience of adolescence. New York: Norton. Steinberg, L. (2008). A social neuroscience perspective on adolescent risk-taking. Development