ORAL UPF/ TESI DOCT Nicotine addiction phenotypes in a BAC transgenic mouse
... The CHRNA5/A3/B4 genomic cluster encodes for the alpha5, alpha3 and beta4 subunits of the nicotinic acetylcholine receptors (nAChRs). Human genetic studies have revealed a significant association of variants in this genomic region with nicotine dependence. However, the mechanisms through which overe ...
... The CHRNA5/A3/B4 genomic cluster encodes for the alpha5, alpha3 and beta4 subunits of the nicotinic acetylcholine receptors (nAChRs). Human genetic studies have revealed a significant association of variants in this genomic region with nicotine dependence. However, the mechanisms through which overe ...
Neuro-Bio-Behavioral Mechanisms of Placebo and Nocebo
... action of drugs as well as “other forces at play and the circumstances surrounding their administration” contribute to the overall treatment effect (Wolf, 1950). Empirical data revealed that placebo effects that endow inert agents with potency or modify the treatment effects of active pharmacologica ...
... action of drugs as well as “other forces at play and the circumstances surrounding their administration” contribute to the overall treatment effect (Wolf, 1950). Empirical data revealed that placebo effects that endow inert agents with potency or modify the treatment effects of active pharmacologica ...
Emotional experiences of tension and suspense: psychological
... the close connection between musical tension and music-evoked emotion. A methodologically similar fMRI study investigating neural correlates of suspense evoked by a literary text found suspenseful text segments to be associated with activity in medial prefrontal, inferior frontal, as well as posteri ...
... the close connection between musical tension and music-evoked emotion. A methodologically similar fMRI study investigating neural correlates of suspense evoked by a literary text found suspenseful text segments to be associated with activity in medial prefrontal, inferior frontal, as well as posteri ...
Previous results from our laboratory have shown that administration
... There are many people I want to thank for helping me through this process and making this dissertation possible. First I want to thank my advisor Dr. Jaime DiazGranados for his help and support throughout my graduate career. Without his willingness to indulge my drive to try new methods, and his fai ...
... There are many people I want to thank for helping me through this process and making this dissertation possible. First I want to thank my advisor Dr. Jaime DiazGranados for his help and support throughout my graduate career. Without his willingness to indulge my drive to try new methods, and his fai ...
Gastric Effects of Cholecystokinin and Its Interaction with Leptin on
... applied only to the gastric compartment and their effects on the NTS neuronal activity were evaluated. The test compounds, CCK and leptin, were dissolved in the vehicle solution. The concentrated solution was applied to the Krebs’ solution in the gastric compartment. The final drug concentration in ...
... applied only to the gastric compartment and their effects on the NTS neuronal activity were evaluated. The test compounds, CCK and leptin, were dissolved in the vehicle solution. The concentrated solution was applied to the Krebs’ solution in the gastric compartment. The final drug concentration in ...
Early Thiamine Deficiency
... positives and false negatives. Recent studies have shifted away from the inhibitor and examined supposed Leigh’s disease patients for genetic defects including those with cytochrome c oxidase deficiency. Leigh’s disease may represent one variation of the inherited ataxias. These studies and their ra ...
... positives and false negatives. Recent studies have shifted away from the inhibitor and examined supposed Leigh’s disease patients for genetic defects including those with cytochrome c oxidase deficiency. Leigh’s disease may represent one variation of the inherited ataxias. These studies and their ra ...
more information
... BACKGROUND: In a previous study conducted at the Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (CMCRC/ERF), we demonstrated for the first time that aspartame (APM) is a multipotent carcinogenic agent when various doses are administered with feed to Sprague-Dawley rats fr ...
... BACKGROUND: In a previous study conducted at the Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (CMCRC/ERF), we demonstrated for the first time that aspartame (APM) is a multipotent carcinogenic agent when various doses are administered with feed to Sprague-Dawley rats fr ...
Glutamine deficiency in the prefrontal cortex increases depressive
... Background: The brain levels of glutamate (Glu) and glutamine (Gln) are partially regulated through the Glu–Gln cycle. Astrocytes play a role in regulating the Glu–Gln cycle, and loss of astrocytes has been associated with depressive disorders. We hypothesized that levels of Glu and Gln would be aff ...
... Background: The brain levels of glutamate (Glu) and glutamine (Gln) are partially regulated through the Glu–Gln cycle. Astrocytes play a role in regulating the Glu–Gln cycle, and loss of astrocytes has been associated with depressive disorders. We hypothesized that levels of Glu and Gln would be aff ...
Extracellular Glutamate, Glutamine, and GABA in the Hippocampus
... depending on whether it originates in one hemisphere or involves the cortex bilaterally, respectively. Epilepsy can be further characterized as idiopathic, which suggests a genetic basis and is not associated with a structural abnormality; symptomatic, in which a structural cause is identified; and ...
... depending on whether it originates in one hemisphere or involves the cortex bilaterally, respectively. Epilepsy can be further characterized as idiopathic, which suggests a genetic basis and is not associated with a structural abnormality; symptomatic, in which a structural cause is identified; and ...
Psilocybin – Summary of knowledge and new perspectives
... Psilocybin is rapidly dephosphorylated to psilocin in the intestinal mucosa by alkaline phosphatase and nonspecific esterase. After ingestion, about 50% of the total volume of psilocin is absorbed from the digestive tract of the rat (Kalberer et al., 1962). After systemic parenteral administration of ...
... Psilocybin is rapidly dephosphorylated to psilocin in the intestinal mucosa by alkaline phosphatase and nonspecific esterase. After ingestion, about 50% of the total volume of psilocin is absorbed from the digestive tract of the rat (Kalberer et al., 1962). After systemic parenteral administration of ...
1
... Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disease characterized by symptoms of inattention, hyperactivity and impulsivity. Converging data from different studies point to ADHD abnormalities in fronto-striatal circuits. Structural neuroimaging studies partially support f ...
... Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disease characterized by symptoms of inattention, hyperactivity and impulsivity. Converging data from different studies point to ADHD abnormalities in fronto-striatal circuits. Structural neuroimaging studies partially support f ...
Explaining The Efficiency Of Marte Meo From A Neurobiological
... mother uses Marte Meo and afterwards analyse it scientifically. Since counselling with Marte Meo is picture based, the development improvements of the child are also recorded on video. All videos are evaluated according to Marte Meo elements with the video interaction analysis (action - reaction), a ...
... mother uses Marte Meo and afterwards analyse it scientifically. Since counselling with Marte Meo is picture based, the development improvements of the child are also recorded on video. All videos are evaluated according to Marte Meo elements with the video interaction analysis (action - reaction), a ...
pathophysiology of attention deficit/ hyperactivity disorder
... of rare reports of sudden death among TCA-treated children, these drugs are not a first-line treatment for ADHD and are only used after carefully weighing the risks and benefits of treating or not treating a child who does not respond to other agents. Other noradrenergic agents help to control ADHD ...
... of rare reports of sudden death among TCA-treated children, these drugs are not a first-line treatment for ADHD and are only used after carefully weighing the risks and benefits of treating or not treating a child who does not respond to other agents. Other noradrenergic agents help to control ADHD ...
frontal functions, connectivity and neural efficiency underpinning
... Neurophysiological fractionation of processes, to include possible inhibition, has been demonstrated between error detection processes and error evaluation processes and with the apparent inhibition or uncoupling of the latter, both of which are processes emanating from the anterior cingulate. These ...
... Neurophysiological fractionation of processes, to include possible inhibition, has been demonstrated between error detection processes and error evaluation processes and with the apparent inhibition or uncoupling of the latter, both of which are processes emanating from the anterior cingulate. These ...
Preview the material
... become excessively attached to objects or routines. The prevalence of Asperger syndrome is not well known. It is not even well recognized prior to the age of 5 or 6, primarily because the individual has normal language development. Asperger syndrome occurs in all ethnic groups and affects every age ...
... become excessively attached to objects or routines. The prevalence of Asperger syndrome is not well known. It is not even well recognized prior to the age of 5 or 6, primarily because the individual has normal language development. Asperger syndrome occurs in all ethnic groups and affects every age ...
stimulant treatment history predicts frontal-striatal
... suppression towards normative levels during cognitive control as well (Liddle et al., 2011; Peterson et al., 2009). Normalization of prefrontal cortex activation has also been observed during emotional processing (Posner et al., 2011). During ...
... suppression towards normative levels during cognitive control as well (Liddle et al., 2011; Peterson et al., 2009). Normalization of prefrontal cortex activation has also been observed during emotional processing (Posner et al., 2011). During ...
Brain glycine receptors as a common target for alcohol and
... and consummatory actions, by using ethanol and substances with possible anti-alcohol effects in the rat. Measurements of extracellular dopamine and amino acid levels in the nAc were made using in vivo brain microdialysis in awake, freely-moving male Wistar rats. In addition, a voluntary ethanol cons ...
... and consummatory actions, by using ethanol and substances with possible anti-alcohol effects in the rat. Measurements of extracellular dopamine and amino acid levels in the nAc were made using in vivo brain microdialysis in awake, freely-moving male Wistar rats. In addition, a voluntary ethanol cons ...
The Placebo Effect: A Psychosocial and Neurobiological Review
... factor in deciding the difference between a new treatment and revealing a sham drug (Kleijnen, de Craen, van Everdingen and Krol, 1994). Alternatively, the placebo effect can be a means of ...
... factor in deciding the difference between a new treatment and revealing a sham drug (Kleijnen, de Craen, van Everdingen and Krol, 1994). Alternatively, the placebo effect can be a means of ...
Neurotoxicity and Mechanism of Toluene Abuse
... Neurotoxicity and Mechanism of Toluene Abuse ments using human subjects are difficult to compare, since they are often methodologically distinct and limited by ethical and safety concerns. In addition, this excitatory-depressive duality correlates to some degree with clinical experience and reports ...
... Neurotoxicity and Mechanism of Toluene Abuse ments using human subjects are difficult to compare, since they are often methodologically distinct and limited by ethical and safety concerns. In addition, this excitatory-depressive duality correlates to some degree with clinical experience and reports ...
5. Gesture as a bridge between action and
... The gestures that speakers produce when they talk are also actions, but they do not have a direct effect on the environment. They do, however, have an effect on communication. Our question, then, is whether actions whose primary function is to represent ideas influence thinking in the same way as ac ...
... The gestures that speakers produce when they talk are also actions, but they do not have a direct effect on the environment. They do, however, have an effect on communication. Our question, then, is whether actions whose primary function is to represent ideas influence thinking in the same way as ac ...
Applications of TMS to Therapy in Psychiatry
... was well tolerated and resulted in a 40% response rate. It is possible that the response rate may have been even better had the treatment period been extended to 3 or 4 weeks. A recent meta-analysis of the open trials of TMS in depression found an effect size of 1.45 (Burt et al., 2002). Although si ...
... was well tolerated and resulted in a 40% response rate. It is possible that the response rate may have been even better had the treatment period been extended to 3 or 4 weeks. A recent meta-analysis of the open trials of TMS in depression found an effect size of 1.45 (Burt et al., 2002). Although si ...
Glia cells, lipid metabolism and Alzheimer`s disease
... (ApoE), the main lipid carrier in the brain, and express lipoprotein receptors involved in the uptakeof lipids. The human ApoE exists in three isoforms of which the ApoE4 isoform is associated with an increased risk of developing Alzheimer’s disease (AD). Furthermore, epidemiological studies reveale ...
... (ApoE), the main lipid carrier in the brain, and express lipoprotein receptors involved in the uptakeof lipids. The human ApoE exists in three isoforms of which the ApoE4 isoform is associated with an increased risk of developing Alzheimer’s disease (AD). Furthermore, epidemiological studies reveale ...
ﻧﺘﺎﯾﺞ داوری ﻣﻘﺎﻻت ﭼﻬﺎرﻣﯿﻦ ﮐﻨﮕﺮه ﻋﻠﻮم اﻋﺼﺎب ﭘﺎﯾﻪ و ﺑﺎ
... Are there Associations between age,education with study field of parents who have children with Autism Spectrum Disorder? Effects of simulated weightlessness on glutamate content of serum, hippocampus and prefrontal cortex of male rats The effects of Vitamin C on hypothyroidism-associated learning a ...
... Are there Associations between age,education with study field of parents who have children with Autism Spectrum Disorder? Effects of simulated weightlessness on glutamate content of serum, hippocampus and prefrontal cortex of male rats The effects of Vitamin C on hypothyroidism-associated learning a ...
INDUCTION AND RECOVERY TIME COURSE OF RAT BRAIN
... especially when induced; these can mediate lipid peroxidation, protein inactivation, and DNA damage, leading to cellular injury (Cederbaum et al., 2001). Elevated levels of CYP2E1 in the central nervous system could thus lead to increased risk of neurotoxicity and influence the cerebral disposition ...
... especially when induced; these can mediate lipid peroxidation, protein inactivation, and DNA damage, leading to cellular injury (Cederbaum et al., 2001). Elevated levels of CYP2E1 in the central nervous system could thus lead to increased risk of neurotoxicity and influence the cerebral disposition ...