Travis, F.T. and Arenander, A. (2006). Cross-Sectional
... technique. The other group (long-term TM group) included 12 subjects (6 male and 6 females, age = 42.3±11.2 years), who had been practicing the TM technique for almost 22 years (21.9±11.2 years). The difference in age was not significantly different (F(1,24) = 1.46, p = .239). All subjects were righ ...
... technique. The other group (long-term TM group) included 12 subjects (6 male and 6 females, age = 42.3±11.2 years), who had been practicing the TM technique for almost 22 years (21.9±11.2 years). The difference in age was not significantly different (F(1,24) = 1.46, p = .239). All subjects were righ ...
Nicotine injections into the ventral tegmental area increase
... pretreatment with the drug. Furthermore, administration of nicotine either systemically, or locally within the ventral tegmental area (VTA), increases extracellular levels of dopamine (DAY in the nucleus accumbens (NAc). In the present study, we examined the effect of local, bilateral injections int ...
... pretreatment with the drug. Furthermore, administration of nicotine either systemically, or locally within the ventral tegmental area (VTA), increases extracellular levels of dopamine (DAY in the nucleus accumbens (NAc). In the present study, we examined the effect of local, bilateral injections int ...
IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque
... (C) Biochemical analyses of Gn-HCL-solubilized Ab42 and Ab40 levels measured by ELISA show significantly increased insoluble Ab42 levels in IL-10-expressing mice compared to controls, but no significant differences in soluble Ab levels (TBSx fraction) are seen. Data represent mean ± SEM. n = 5-7 mic ...
... (C) Biochemical analyses of Gn-HCL-solubilized Ab42 and Ab40 levels measured by ELISA show significantly increased insoluble Ab42 levels in IL-10-expressing mice compared to controls, but no significant differences in soluble Ab levels (TBSx fraction) are seen. Data represent mean ± SEM. n = 5-7 mic ...
GABA-Based Evaluation of Neurologic Conditions: MR Spectroscopy
... seizure activity—reduced GABA would be expected to allow unbridled excitatory neural activity. In line with this theory, antiepileptic medications generally have an effect on increasing GABAergic activity and decreasing CSF levels of GABA.28 Moreover, antibodies to GAD have been detected in many gro ...
... seizure activity—reduced GABA would be expected to allow unbridled excitatory neural activity. In line with this theory, antiepileptic medications generally have an effect on increasing GABAergic activity and decreasing CSF levels of GABA.28 Moreover, antibodies to GAD have been detected in many gro ...
Resting-state Functional mR imaging
... still evolving, new disease insights are emerging in a variety of neurologic and psychiatric disorders. The default mode network is affected in Alzheimer disease and various other diseases of cognitive impairment. Alterations in RSNs have been identified in many diseases, in the absence of evident s ...
... still evolving, new disease insights are emerging in a variety of neurologic and psychiatric disorders. The default mode network is affected in Alzheimer disease and various other diseases of cognitive impairment. Alterations in RSNs have been identified in many diseases, in the absence of evident s ...
Neurophysiology of synesthesia. - Hal-CEA
... Synesthesia is an experience in which stimulation in one sensory or cognitive stream leads to associated experiences in a second, unstimulated stream. The stimulus which elicits a synesthetic experience is called the inducer, the additional sensations are called concurrents, and various forms of syn ...
... Synesthesia is an experience in which stimulation in one sensory or cognitive stream leads to associated experiences in a second, unstimulated stream. The stimulus which elicits a synesthetic experience is called the inducer, the additional sensations are called concurrents, and various forms of syn ...
Coexposure of Neonatal Mice to a Flame
... deleterious effects on cognitive development. The interaction between environmental pollutants is suggested as one reason for the observed defective neurological development in children from the Faeroe Islands as compared to children from the Seychelles. We have previously seen in mice that polychlo ...
... deleterious effects on cognitive development. The interaction between environmental pollutants is suggested as one reason for the observed defective neurological development in children from the Faeroe Islands as compared to children from the Seychelles. We have previously seen in mice that polychlo ...
A Critical Review of Secondary Neurodegeneration
... that [11C]PiB is recognised to have particularly high binding affinity for amyloid fibrils found in dense core plaques but low binding affinity to soluble oligomers or non-fibril amyloid-β forms [31]. Therefore, [11C]PiB and like Congo Red and Thioflavin T are limited in their ability to detect amyl ...
... that [11C]PiB is recognised to have particularly high binding affinity for amyloid fibrils found in dense core plaques but low binding affinity to soluble oligomers or non-fibril amyloid-β forms [31]. Therefore, [11C]PiB and like Congo Red and Thioflavin T are limited in their ability to detect amyl ...
Document
... brain and peripheral tissue as ubiquitous and tissue-specific alternatively spliced isoforms that regulate membrane dynamics and endocytosis in multiple cell types. The function of BIN1 in the brain and the mechanism(s) by which AD-associated BIN1 alleles increase the risk for the disease are not kn ...
... brain and peripheral tissue as ubiquitous and tissue-specific alternatively spliced isoforms that regulate membrane dynamics and endocytosis in multiple cell types. The function of BIN1 in the brain and the mechanism(s) by which AD-associated BIN1 alleles increase the risk for the disease are not kn ...
Varieties of Analogical Reasoning
... Pre-hoc (“before this”) analogies occur in discovery contexts, as in most scientific analogy. In Thagard's (1989) terms, the goal is to find coherent explanations, that is, to help one understand some given new concept or observation (and generate ideas for further hypothesis tests or observations). ...
... Pre-hoc (“before this”) analogies occur in discovery contexts, as in most scientific analogy. In Thagard's (1989) terms, the goal is to find coherent explanations, that is, to help one understand some given new concept or observation (and generate ideas for further hypothesis tests or observations). ...
A Study on Finding the Key Motive of Happiness Using Fuzzy
... on. People without happiness will be selfish and disturb others happiness also. The key motive of development is happiness. We can see from the data, the key motive of happiness is living with their loved one and making them happy, the word dear one includes friends, family and life partner. Secondl ...
... on. People without happiness will be selfish and disturb others happiness also. The key motive of development is happiness. We can see from the data, the key motive of happiness is living with their loved one and making them happy, the word dear one includes friends, family and life partner. Secondl ...
B-Lymphocyte-Mediated Delayed Cognitive Impairment following
... stroke are at increased risk of developing dementia, and approximately one-third will eventually suffer from vascular dementia (Barba et al., 2000; Leys et al., 2005; Béjot et al., 2011). In many of these patients, dementia might be caused by an associated comorbidity, but even after controlling fo ...
... stroke are at increased risk of developing dementia, and approximately one-third will eventually suffer from vascular dementia (Barba et al., 2000; Leys et al., 2005; Béjot et al., 2011). In many of these patients, dementia might be caused by an associated comorbidity, but even after controlling fo ...
Richard_Wainess_Diss.. - Engineering Class Home Pages
... problem solving tasks in 2-D environments. This study combined these two topics by examining complex problem solving tasks in a 3-D, occluded computer-based video game. Three of the study’s five hypotheses proposed that navigation map usage would result in greater content understanding and problem s ...
... problem solving tasks in 2-D environments. This study combined these two topics by examining complex problem solving tasks in a 3-D, occluded computer-based video game. Three of the study’s five hypotheses proposed that navigation map usage would result in greater content understanding and problem s ...
Rewarding properties of sildenafil citrate in mice
... The Food and Drug Administration approved sildenafil (Viagra, Pfizer Inc., NY, USA) as the first oral pill to treat erectile dysfunction on 27 March, 1998. The drug quickly gained popularity and it is estimated that since its approval, more than 16 million men worldwide have used the drug (Swearinge ...
... The Food and Drug Administration approved sildenafil (Viagra, Pfizer Inc., NY, USA) as the first oral pill to treat erectile dysfunction on 27 March, 1998. The drug quickly gained popularity and it is estimated that since its approval, more than 16 million men worldwide have used the drug (Swearinge ...
Molecules and circuits involved in nicotine addiction: The many
... subunits have shown that activation of receptors containing the a4 or a6 subunits is sufficient for nicotine-mediated stimulation of DA neuron firing and for nicotine preference in conditioned place preference paradigm (Drenan et al., 2008; Tapper et al., 2004). Similarly, knockout studies have shown ...
... subunits have shown that activation of receptors containing the a4 or a6 subunits is sufficient for nicotine-mediated stimulation of DA neuron firing and for nicotine preference in conditioned place preference paradigm (Drenan et al., 2008; Tapper et al., 2004). Similarly, knockout studies have shown ...
Are there three subdivisions in the primate subthalamic nucleus? Max C. Keuken
... apparent pattern to reflect an underlying anatomical organization (p. 110)”; as another example, Karachi et al. (2004) mention: “In summary, the pallidosubthalamic projection appears to be topographically arranged, with the sensorimotor part of the STN occupying its dorsolateral half, and the limbic ...
... apparent pattern to reflect an underlying anatomical organization (p. 110)”; as another example, Karachi et al. (2004) mention: “In summary, the pallidosubthalamic projection appears to be topographically arranged, with the sensorimotor part of the STN occupying its dorsolateral half, and the limbic ...
Wager, T. D., Kang, J., Johnson, T. D., Nichols, T. E., Satpute, A. B.
... one emotion type from another, it is not clear that these findings are reliable enough (with sufficiently large effects) or generalizable enough across studies to meaningfully use brain information to infer what type of emotion was experienced. Recently, studies have begun to take a pattern-based vi ...
... one emotion type from another, it is not clear that these findings are reliable enough (with sufficiently large effects) or generalizable enough across studies to meaningfully use brain information to infer what type of emotion was experienced. Recently, studies have begun to take a pattern-based vi ...
Mental Simulation and Meaning in Life
... What is more, when people lack well-developed causal reasoning capacities, they become particularly prone to these teleological explanations (Kelemen & DiYanni, 2005; Lombrozo, Kelemen, & Zaitchik, 2007), suggesting that inferring the intentions of a supernatural designer provides a way of understan ...
... What is more, when people lack well-developed causal reasoning capacities, they become particularly prone to these teleological explanations (Kelemen & DiYanni, 2005; Lombrozo, Kelemen, & Zaitchik, 2007), suggesting that inferring the intentions of a supernatural designer provides a way of understan ...
Effort and Valuation in the Brain
... they were given 12 practice trials in which they experienced six noof 0.02% fmax; SD ⫽ 0.002%). We could not smooth force during the squeeze trials. Participants underwent 4 scanning sessions with a rest training day because subjects still made errors and force shape was not period (up to 3 min) bet ...
... they were given 12 practice trials in which they experienced six noof 0.02% fmax; SD ⫽ 0.002%). We could not smooth force during the squeeze trials. Participants underwent 4 scanning sessions with a rest training day because subjects still made errors and force shape was not period (up to 3 min) bet ...
Author`s personal copy - Laboratoire de Neurosciences Cognitives
... segment of the globus pallidus (GPi). The anatomo-physiological organization of the BG and their output suggested that interfering with such hyper-activity could restore motor function and improve parkinsonism. Several animal models in rodents and primates, as well as clinical studies and neurosurgi ...
... segment of the globus pallidus (GPi). The anatomo-physiological organization of the BG and their output suggested that interfering with such hyper-activity could restore motor function and improve parkinsonism. Several animal models in rodents and primates, as well as clinical studies and neurosurgi ...
Newborn infants` auditory system is sensitive to Western music
... discrimination tasks (Tiitinen et al., 1994; Amenedo and Escera, 2000; Novitski et al., 2004). In infants, change-related responses to auditory stimuli are present already at birth (e.g., Alho et al., 1990; He et al., 2007, 2009; Novitski et al., 2007) and even during the fetal period (Huotilainen e ...
... discrimination tasks (Tiitinen et al., 1994; Amenedo and Escera, 2000; Novitski et al., 2004). In infants, change-related responses to auditory stimuli are present already at birth (e.g., Alho et al., 1990; He et al., 2007, 2009; Novitski et al., 2007) and even during the fetal period (Huotilainen e ...
The Placebo Effect
... placebo effect, or response, is a biological phenomenon that is due to the psychosocial context of the patient and the therapy. It is important to point out that contextual and social stimuli may affect the patient’s brain and body in many ways, such that there is not a single placebo effect but ins ...
... placebo effect, or response, is a biological phenomenon that is due to the psychosocial context of the patient and the therapy. It is important to point out that contextual and social stimuli may affect the patient’s brain and body in many ways, such that there is not a single placebo effect but ins ...
PDE5 Exists in Human Neurons and is a Viable Therapeutic Target
... for a variety of neurologic diseases. Although many of these studies have focused on Alzheimer’s disease, the PDE5 literature suggests that PDE5 inhibition may be therapeutic in a variety of neurological disorders (see Discussion). Despite the successes in the animal literature, PDE5 inhibitors have ...
... for a variety of neurologic diseases. Although many of these studies have focused on Alzheimer’s disease, the PDE5 literature suggests that PDE5 inhibition may be therapeutic in a variety of neurological disorders (see Discussion). Despite the successes in the animal literature, PDE5 inhibitors have ...
Chapter 1
... specialize, with newborns showing greater electrical brain activity in the left hemisphere than the right hemisphere when listening to speech. ...
... specialize, with newborns showing greater electrical brain activity in the left hemisphere than the right hemisphere when listening to speech. ...
Mirror neurons in humans: Consisting or confounding
... & Decety, 2001). However, since this seminal review, a number of fMRI and PET studies have been conducted to reveal a functional equivalence between observing and performing an action. Therefore such new evidence calls for a re-assessment of this literature. Herein we pose the following question: ha ...
... & Decety, 2001). However, since this seminal review, a number of fMRI and PET studies have been conducted to reveal a functional equivalence between observing and performing an action. Therefore such new evidence calls for a re-assessment of this literature. Herein we pose the following question: ha ...