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Nervous System A major control and communication system Neuron • “neur-” means nerve, so a neuron is a nerve cell • Cell body is the part where the organelles, such as the nucleus, are located • Dendrite is the receiving end of the neuron • Axon is the transmitting or conducting end of the neuron Nerve • A group of neurons (specifically their axons) that are bundled together anywhere except the brain/spinal cord, is termed a nerve Nerve impulse • A nerve impulse is an electrical message traveling along a neuron. Synapse • A junction between adjacent neurons • Neurotransmitters are chemicals carrying nerve message across the synapse Myelin • Some neurons have their axons coated in a fatty substance called myelin. • Myelin increases the speed of nerve impulse transmission – as high as 200 mph • White matter Central Nervous System • • • • • Brain Spinal Cord Control, information processing Thoughts are formed Memory is stored Peripheral Nervous System • Carries messages to and from the CNS • Sensory – carries information towards the CNS • Motor – carries information away from the CNS to the muscles and glands PNS • Somatic motor information travels to skeletal muscles • Autonomic motor information travels to cardiac muscle, smooth muscle and glands; responsible for your Fight or Flight response Brain • “enceph-” means brain • Located in skull • Medulla oblongata is part of the brainstem and controls important reflexes that control breathing, heart rate and blood pressure. Also is the site where motor and sensory pathways cross. Brain • Hypothalamus is a center of homeostasis mechanisms such as hunger, thirst, water balance, temperature regulation; makes hormones, and controls the Autonomic Nervous System. Brain • Thalamus is a sensory relay center Brain • Cerebrum is the largest and highest center of the brain • Responsible for conscious awareness, thinking, intelligence, memory and deciding your response to sensory input. Brain • Electroencephalogram, or EEG, is a recording of the brain’s electrical activity, commonly called brain waves. Spinal cord • • • • “myel-” means spinal cord Located within your vertebrae Sends sensory messages to your brain Carries motor messages away from your brain Spinal Reflexes • A reflex is an autonomic, quick response to a stimulus. The reflex is repeatable. • Spinal reflexes involve the spinal cord and do not involve conscious thought from the brain. CNS Meninges • Meninges are tough, protective membranes that surround the brain and spinal cord. • Within the meninges is Cerebrospinal Fluid (CSF) that cushions and provides nourishment for the CNS • What is meningitis? Nervous System Pathology • Brain damage • The brain requires oxygen for aerobic metabolism. Lack of oxygen for more than 5 minutes can kill brain cells. • The brain requires glucose for metabolism. Lack of glucose for more than 15 minutes kills brain cells. • Neurons cannot undergo mitosis. Epilepsy • Brain fires abnormal signals that travel to skeletal muscles. • Skeletal muscles contract leading to seizures. • May lose consciousness in larger seizures • Causes are injury, infection, genetic predisposition, and many causes are unknown Epilepsy • Treatments include correcting the cause, if known; • Decreasing the frequency and magnitude of the seizures with medications. Multiple Sclerosis • Many “hard” scars form along the myelin sheaths of neurons • Autoimmune disease • Numerous short circuits occur resulting in difficulty in vision, memory, walking and judgment • Chronic disease that progresses slowly Cerebral Palsy • Motor centers are damaged at the time of birth • Causes include German Measles, radiation exposure, oxygen starvation to the baby’s brain at the time of delivery • Results in varying degrees of impairment of motor abilities.