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Biology 6C Variation among organisms Identify and illustrate how changes in DNA cause mutations and evaluate the significance of these changes . Mutation Any change in the DNA sequence. Can lead to a change in protein production. DNAmRNA- Amino Acid chain (Protein)- Practice Question If one nucleotide is omitted or accidentally repeated in the process of DNA replication, which of the following is most likely to occur? F. Gene deletion G. Gene mutation H. Gene insertion J. Gene segregation Practice Question This illustration is an example of a normal DNA sequence. Which of the following represents a single base change in the sequence?