Download AACR and other questions to be used as extra credit at end of 2150

AACR and other questions to be used as extra credit at end of 2150
1. The following is a DNA sequence. The coding sequence of the gene is in bold and italicized and the
promoter is underlined.
DNA 5’ T G*A A G G A A T T A T A A T A C G A C C A T G A T G T A C G C A T A A A C G T 3’
A mutation occurs in which a base (T) is inserted into the DNA sequence after the G, at the position
marked with an asterisk, before transcription begins. How will this alteration influence the mRNA
sequence that is made from this DNA sequence?
2. A child is born with two X chromosomes and one Y chromosome. One way this can occur is due to a
mistake in separation of chromosomes in the production of the egg in either meiosis I or II. Explain
another way this could occur.
3. A woman and a man have the same mutation in a gene on the X chromosome. This gene normally
encodes for a protein required for blood clotting. The mutation results in no protein product being
made from this gene. Each of them has one copy of this mutation. Ignore the possible effects of X
inactivation. How would a biologist: A. explain how this mutation could affect the woman? B. explain
how this mutation could affect the man?
4. A scientist researching a gene in human uses mice to conduct her research because mice have a gene
that is very similar to the human gene. When the scientist looks at the human and mouse DNA and
amino acid sequences for these similar genes, she finds that the amino acid sequences are more similar
than the DNA sequences. How would she explain this finding?