Determining the Transcription Factor Genes Populating a Fruit Fly
... bab2 genes. These transgene lines came from the Vienna Drosophila RNAi Center (Dietzl et al., 2007). The Transgenic RNAi Project lines were derived by use of the VALIUM1 and VALIUM10 vectors which include long dsRNA hairpin (Ni et.al., 2008, 2009), while lines produced from the VALIUM20, VALIUM21, a ...
... bab2 genes. These transgene lines came from the Vienna Drosophila RNAi Center (Dietzl et al., 2007). The Transgenic RNAi Project lines were derived by use of the VALIUM1 and VALIUM10 vectors which include long dsRNA hairpin (Ni et.al., 2008, 2009), while lines produced from the VALIUM20, VALIUM21, a ...
Genetic polymorphisms among C57BL/6 mouse inbred strains
... strain that is used, or the C57BL/6 strain from which ES cells were originally derived for the generation of the corresponding mouse knock-out, are crucial for the correct design and interpretation of the corresponding experiment involving any of these mice. There are two major substrains of C57BL/6 ...
... strain that is used, or the C57BL/6 strain from which ES cells were originally derived for the generation of the corresponding mouse knock-out, are crucial for the correct design and interpretation of the corresponding experiment involving any of these mice. There are two major substrains of C57BL/6 ...
Haemophilia (2013) - Haemophilia Foundation Australia
... Haemophilia B, also known as Christmas Disease, is caused by having reduced levels of clotting factor IX (9). Haemophilia is not contagious. There is also another bleeding disorder known as acquired haemophilia, which is not inherited like the classical form of haemophilia. This is a very rare condi ...
... Haemophilia B, also known as Christmas Disease, is caused by having reduced levels of clotting factor IX (9). Haemophilia is not contagious. There is also another bleeding disorder known as acquired haemophilia, which is not inherited like the classical form of haemophilia. This is a very rare condi ...
Mutations affecting development of the notochord in zebrafish
... Allelism was tested first between mutations producing similar phenotypes. This defined a smaller number of complementation groups between which complementation tests were subsequently performed. For each complementation test an identified, confirmed heterozygous fish of one genotype was crossed with ...
... Allelism was tested first between mutations producing similar phenotypes. This defined a smaller number of complementation groups between which complementation tests were subsequently performed. For each complementation test an identified, confirmed heterozygous fish of one genotype was crossed with ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... congenital cutis laxa in association with severe central nervous system involvement, brain migration defects, seizures, and hearing loss. The X-linked form is currently classified in the group of copper transport diseases. The precise cause is unknown, but it may be due to abnormal elastin metabolis ...
... congenital cutis laxa in association with severe central nervous system involvement, brain migration defects, seizures, and hearing loss. The X-linked form is currently classified in the group of copper transport diseases. The precise cause is unknown, but it may be due to abnormal elastin metabolis ...
NF1 Gene Test Review - The Friedman Lab at UBC
... disease, central nervous system (CNS) tumors, or malignant peripheral nerve sheath tumors. NF1 is characterized by extreme clinical variability, not only among unrelated individuals and among affected individuals within a single family but also even within a single person at different times in life. ...
... disease, central nervous system (CNS) tumors, or malignant peripheral nerve sheath tumors. NF1 is characterized by extreme clinical variability, not only among unrelated individuals and among affected individuals within a single family but also even within a single person at different times in life. ...
2.1.databases_intro - T
... Fully-annotated (manually), non-redundant, crossreferenced, documented protein sequence database. ~100 ’000 sequences from more than 6’800 different species; 70 ’000 references (publications); 550 ’000 crossreferences (databases); ~200 Mb of annotations. ...
... Fully-annotated (manually), non-redundant, crossreferenced, documented protein sequence database. ~100 ’000 sequences from more than 6’800 different species; 70 ’000 references (publications); 550 ’000 crossreferences (databases); ~200 Mb of annotations. ...
GENETIC AND MOLECULAR ANALYSIS OF THE garnet EYE
... A critical test of this model requires molecular cloning and analysis of the individual members of the transport group of eye colour genes. Preliminary molecular analysis of the garnet gene is reported in chapter two. The garnet gene is expressed in many different tissues at different stages in deve ...
... A critical test of this model requires molecular cloning and analysis of the individual members of the transport group of eye colour genes. Preliminary molecular analysis of the garnet gene is reported in chapter two. The garnet gene is expressed in many different tissues at different stages in deve ...
anatomical skin dimples
... fissure follows the fissure in the lower jaw bone that resulted from the incomplete fusion of the left and right halves of the jaw bone, or muscle, during the embryonal and fetal development. For other individuals, it can develop over time, often because one half of the jaw is longer than the other, ...
... fissure follows the fissure in the lower jaw bone that resulted from the incomplete fusion of the left and right halves of the jaw bone, or muscle, during the embryonal and fetal development. For other individuals, it can develop over time, often because one half of the jaw is longer than the other, ...
X-Chromosome inactivation ratios affect wild-type
... head growth, ataxia, autistic features, seizures and breathing abnormalities (3). RTT is caused by mutations in MECP2, encoding methyl-CpG-binding protein 2 (MeCP2) (4). Although MECP2 is ubiquitously expressed at the transcriptional level (5 – 7), tissue-specific and developmental regulation of MEC ...
... head growth, ataxia, autistic features, seizures and breathing abnormalities (3). RTT is caused by mutations in MECP2, encoding methyl-CpG-binding protein 2 (MeCP2) (4). Although MECP2 is ubiquitously expressed at the transcriptional level (5 – 7), tissue-specific and developmental regulation of MEC ...
The Plasmodium 6-cysteine protein family in sexual and sporozoite
... disease malaria, which is primarily caused by the parasites Plasmodium falciparum and Plasmodium vivax [1] and is transmitted to humans by Anopheles mosquitoes. P. falciparum is the cause of most mortality and although P. vivax is perceived as benign, both Plasmodia actually account for severe disea ...
... disease malaria, which is primarily caused by the parasites Plasmodium falciparum and Plasmodium vivax [1] and is transmitted to humans by Anopheles mosquitoes. P. falciparum is the cause of most mortality and although P. vivax is perceived as benign, both Plasmodia actually account for severe disea ...
Engrailed cooperates with extradenticle and homothorax to repress
... Fig. 1F-H, complete removal of both maternal and zygotic exd function caused a dramatic drop in En repression activity on the slp gene. However, as with hth, there appeared to be residual activity even in the absence of exd function. Thus, although En retains a residual repression activity in vivo w ...
... Fig. 1F-H, complete removal of both maternal and zygotic exd function caused a dramatic drop in En repression activity on the slp gene. However, as with hth, there appeared to be residual activity even in the absence of exd function. Thus, although En retains a residual repression activity in vivo w ...
Visceral endoderm-restricted translation of Otx1
... dorsal telencephalon where Otx2 is not transcribed. Therefore, these findings support two hypotheses: (i) Otx1 and Otx2 functional properties might largely overlap and differences in their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice ...
... dorsal telencephalon where Otx2 is not transcribed. Therefore, these findings support two hypotheses: (i) Otx1 and Otx2 functional properties might largely overlap and differences in their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice ...
Table S1.
... the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism [goid 46961] [evidence IEA]; Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate = ATP + H2O, coupled with t ...
... the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism [goid 46961] [evidence IEA]; Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate = ATP + H2O, coupled with t ...
Spina Bifida
... managed? Treatment for spina bifida depends on the extent of spinal cord involvement - Spina bifida occulta usually requires no treatment unless pain from tethering develops - Meningocele usually requires removal and early management of the cyst - Myelomeningocele usually requires the most extensive ...
... managed? Treatment for spina bifida depends on the extent of spinal cord involvement - Spina bifida occulta usually requires no treatment unless pain from tethering develops - Meningocele usually requires removal and early management of the cyst - Myelomeningocele usually requires the most extensive ...
Establishing neuroblast-specific gene expression in the Drosophila
... Huckebein is observed in position-specific neuroectodermal clusters and neuroblasts The spatial pattern of Hkb in the neuroectoderm is complex but highly reproducible (Fig. 1D-F). The neuroectoderm can be divided into seven rows along the A/P axis and three columns along the mediolateral axis; these ...
... Huckebein is observed in position-specific neuroectodermal clusters and neuroblasts The spatial pattern of Hkb in the neuroectoderm is complex but highly reproducible (Fig. 1D-F). The neuroectoderm can be divided into seven rows along the A/P axis and three columns along the mediolateral axis; these ...
Asymmetries in Retrieval of Gene Function Information
... of the source followed by a slash followed by an accession number and can be searched with one or both components, e.g., genbank [si], AF001892 [si], genbank/AF001892 [si]. The SI field and the Entrez sequence database links are not linked. The PubMed links to these databases are created from the re ...
... of the source followed by a slash followed by an accession number and can be searched with one or both components, e.g., genbank [si], AF001892 [si], genbank/AF001892 [si]. The SI field and the Entrez sequence database links are not linked. The PubMed links to these databases are created from the re ...
Ingenuity Variant Analysis
... enzyme that inactivates thiopurine drugs, which are used to treat certain cancers of the bone marrow, various auto-immune diseases and transplant patients. Individuals with reduced activity of the TPMT enzyme are more likely to suffer from toxic effects following treatment with conventional doses of ...
... enzyme that inactivates thiopurine drugs, which are used to treat certain cancers of the bone marrow, various auto-immune diseases and transplant patients. Individuals with reduced activity of the TPMT enzyme are more likely to suffer from toxic effects following treatment with conventional doses of ...
Section 1 The application - Office of the Gene Technology Regulator
... must follow when considering an application for a licence to intentionally release a genetically modified organism (GMO) into the environment. For a licence to be issued, the Regulator must be satisfied that the release will not pose any risks to human health and safety and the environment that can ...
... must follow when considering an application for a licence to intentionally release a genetically modified organism (GMO) into the environment. For a licence to be issued, the Regulator must be satisfied that the release will not pose any risks to human health and safety and the environment that can ...
PROGRAM PROGRAM
... during plant development (Wen-Hui Shen) – 30 min • Genome-wide analyses of Arabidopsis chromatin remodeler BRM reveal its functions in transcription regulation and plant growth control (R. Archacki) – 30 min • HD2C histone deacetylase and a SWI/SNF complex are both involved in mediating the heat s ...
... during plant development (Wen-Hui Shen) – 30 min • Genome-wide analyses of Arabidopsis chromatin remodeler BRM reveal its functions in transcription regulation and plant growth control (R. Archacki) – 30 min • HD2C histone deacetylase and a SWI/SNF complex are both involved in mediating the heat s ...
Tapanes-Castillo A, Weaver EJ, Smith RP, Kamei Y, Caspary T, Hamilton-Nelson KL, Slifer SH, Martin ER, Bixby JL, Lemmon VP. Neurogenetics. 2012 Feb;11(1):53-71. A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice.
... on the reason for the defect in CSF flow. Communicating hydrocephalus arises from problems with CSF secretion or resorption; CSF flows freely between the ventricles and the subarachnoid space. On the other hand, noncommunicating hydrocephalus develops when a physical obstruction blocks CSF flow betw ...
... on the reason for the defect in CSF flow. Communicating hydrocephalus arises from problems with CSF secretion or resorption; CSF flows freely between the ventricles and the subarachnoid space. On the other hand, noncommunicating hydrocephalus develops when a physical obstruction blocks CSF flow betw ...
Expression and characterization of von Willebrand
... on multimer analysis of vWF, which found absence of the triplet structure and absence of HMWM from both plasma and platelets. The fastest migrating electrophoretic band was not pronounced12 (Figure 1), which is in contrast to findings in vWD 2A/IIC. The markedly reduced vWF:Ag levels in the patient ...
... on multimer analysis of vWF, which found absence of the triplet structure and absence of HMWM from both plasma and platelets. The fastest migrating electrophoretic band was not pronounced12 (Figure 1), which is in contrast to findings in vWD 2A/IIC. The markedly reduced vWF:Ag levels in the patient ...
Creating order from chaos: epigenome dynamics in
... insertions providing evidence for cis-regulatory information (Selinger et al., 2001; Naito ...
... insertions providing evidence for cis-regulatory information (Selinger et al., 2001; Naito ...
The Genetics of Migraine
... type—with or without aura—but about a third experience both types of attacks during their life. We do not yet know whether migraine with and without aura are two clinical forms of the same disease, or whether they represent two distinct disorders. There are also other less common types of migraine. ...
... type—with or without aura—but about a third experience both types of attacks during their life. We do not yet know whether migraine with and without aura are two clinical forms of the same disease, or whether they represent two distinct disorders. There are also other less common types of migraine. ...
Attachment 2.2 Sequencing results
... tumour initiation and progression. [19-22] The TCDD-dependant release from contact inhibition seems to be a common phenomenon as it is observed in several cell lines. [23] In the human breast cancer epithelial cell line MCF-7 a down regulation of E-cadherin (a transmembrane protein playing an import ...
... tumour initiation and progression. [19-22] The TCDD-dependant release from contact inhibition seems to be a common phenomenon as it is observed in several cell lines. [23] In the human breast cancer epithelial cell line MCF-7 a down regulation of E-cadherin (a transmembrane protein playing an import ...