SPATULA, a bHLH carpel development gene
... cDNA 3.5 corresponds to predicted gene 44 in the AP2 contig of Terryn et al. (1999) (also called AT4g36930 by the Martinsried Institute for Protein Sequences, see http://www.mips.biochem.mpg.de/proj/thal/). Comparison of cDNA 3.5 and the predicted ORF suggested that it is not full length. Two longer ...
... cDNA 3.5 corresponds to predicted gene 44 in the AP2 contig of Terryn et al. (1999) (also called AT4g36930 by the Martinsried Institute for Protein Sequences, see http://www.mips.biochem.mpg.de/proj/thal/). Comparison of cDNA 3.5 and the predicted ORF suggested that it is not full length. Two longer ...
Full Text
... Mutation of the winged-helix gene HNF3β leads to loss of the node and its derivatives, while mutation of the homeobox gene Otx2 results in loss of head structures, apparently at least partially because of defects in the AVE. To investigate the potential genetic interactions between the two signaling ...
... Mutation of the winged-helix gene HNF3β leads to loss of the node and its derivatives, while mutation of the homeobox gene Otx2 results in loss of head structures, apparently at least partially because of defects in the AVE. To investigate the potential genetic interactions between the two signaling ...
Brahman Genetics Negatively Impact Protein Degradation and
... Reports by an authorized administrator of New Prairie Press. Copyright March 2017 Kansas State University Agricultural Experiment Station and Cooperative Extension Service. Contents of this publication may be freely reproduced for educational purposes. All other rights reserved. Brand names appearin ...
... Reports by an authorized administrator of New Prairie Press. Copyright March 2017 Kansas State University Agricultural Experiment Station and Cooperative Extension Service. Contents of this publication may be freely reproduced for educational purposes. All other rights reserved. Brand names appearin ...
Additional Table 1. Genotype and phenotype of the
... were performed. The clinical significance of these copy number variants is unclear. ...
... were performed. The clinical significance of these copy number variants is unclear. ...
Interactions between the otitis media gene, Fbxo11, and p53 in the
... Otitis Media with effusion (OME) is the most common cause of hearing loss in children and tympanostomy to alleviate the condition remains the commonest surgical intervention in children in the developed world. Chronic and recurrent forms of OM are known to have a very significant genetic component, ...
... Otitis Media with effusion (OME) is the most common cause of hearing loss in children and tympanostomy to alleviate the condition remains the commonest surgical intervention in children in the developed world. Chronic and recurrent forms of OM are known to have a very significant genetic component, ...
Concentrations of the atherogenic Lp(a) are elevated in FH
... Defects in the LDL receptor (LDLR) gene give rise to familial hypercholesterolaemia (FH), a condition characterised by high LDL cholesterol, xanthomatosis, and premature coronary heart disease (CHD).1 High concentrations in plasma of Lp(a), a covalent complex of LDL and the plasminogen-related apoli ...
... Defects in the LDL receptor (LDLR) gene give rise to familial hypercholesterolaemia (FH), a condition characterised by high LDL cholesterol, xanthomatosis, and premature coronary heart disease (CHD).1 High concentrations in plasma of Lp(a), a covalent complex of LDL and the plasminogen-related apoli ...
Charles K. Wairuri , Jacquie E. van der Waals
... different pili (Fronzes et al. 2008), the type IV pili (T4P) are the most abundant pili described ...
... different pili (Fronzes et al. 2008), the type IV pili (T4P) are the most abundant pili described ...
The Nodal Pathway Acts Upstream of Hedgehog
... 1998). However, the source, exact role, site, and time of action of Hh proteins during anterior CNS patterning remain uncertain. For instance, although shh is expressed within the telencephalon, the endogenous source of Hh proteins that influence early development of this region are uncertain and pr ...
... 1998). However, the source, exact role, site, and time of action of Hh proteins during anterior CNS patterning remain uncertain. For instance, although shh is expressed within the telencephalon, the endogenous source of Hh proteins that influence early development of this region are uncertain and pr ...
Gene Section BIN1 (bridging integrator 1) Atlas of Genetics and Cytogenetics
... exchange factors (Rab GEFs) and the sorting nexin protein Snx4. Complexes of neuronal Amph-I with neuron-specific isoforms of Bin1 (Amph-II) have been implicated in synaptic vesicle recycling in the brain. Genetic studies of the Bin1 homolog in budding yeast indicate an essential role in endocytosis ...
... exchange factors (Rab GEFs) and the sorting nexin protein Snx4. Complexes of neuronal Amph-I with neuron-specific isoforms of Bin1 (Amph-II) have been implicated in synaptic vesicle recycling in the brain. Genetic studies of the Bin1 homolog in budding yeast indicate an essential role in endocytosis ...
Thalassaemia Information Leaflet
... itself makes the body absorb more iron from food. If the excess iron is not removed, it can damage internal organs and cause complications. Chelation helps the body get rid of excess iron. This treatment is really important for preventing complications. There are different forms of chelation: deferi ...
... itself makes the body absorb more iron from food. If the excess iron is not removed, it can damage internal organs and cause complications. Chelation helps the body get rid of excess iron. This treatment is really important for preventing complications. There are different forms of chelation: deferi ...
Pathogenesis - North East Sleep Society
... Some RLS patients present with iron deficiency. Their serum and CSF ferritin levels are low (Earley et al, 2000). With MRI, Allen et al. (2001) revealed that RLS patient’s iron level is low at the Substantia Nigra (SN) area and the MRI iron values of this area correlate with RLS severity. ...
... Some RLS patients present with iron deficiency. Their serum and CSF ferritin levels are low (Earley et al, 2000). With MRI, Allen et al. (2001) revealed that RLS patient’s iron level is low at the Substantia Nigra (SN) area and the MRI iron values of this area correlate with RLS severity. ...
Reprint
... the organismal soma, the intracellular cytoplasm (excluding cytoplasmic DNA), and the proteins and methyl-groups associated with the DNA molecule. Nongenetic inheritance thus comprises mechanisms whereby the environment within which an ancestor’s genes reside influences development in descendants (Ta ...
... the organismal soma, the intracellular cytoplasm (excluding cytoplasmic DNA), and the proteins and methyl-groups associated with the DNA molecule. Nongenetic inheritance thus comprises mechanisms whereby the environment within which an ancestor’s genes reside influences development in descendants (Ta ...
Alternatively Spliced Genes
... RNA precursor, or pre-mRNA) (as depicted in •Fig. 1). The discovery of split genes in the viral genome and subsequent research in the field of pre-mRNA splicing have greatly advanced our understanding of mammalian gene regulation. Studies on pre-mRNA splicing have also facilitated sequence analyses o ...
... RNA precursor, or pre-mRNA) (as depicted in •Fig. 1). The discovery of split genes in the viral genome and subsequent research in the field of pre-mRNA splicing have greatly advanced our understanding of mammalian gene regulation. Studies on pre-mRNA splicing have also facilitated sequence analyses o ...
redundancy and regulatory interactions between two
... (AF052570), suggesting a possible role for this sequence in the negative regulation of C-function gene expression (Figure 1B). Two types of FAR cDNA were identified in the cDNA library at different frequencies. The DNA sequence and predicted amino acid-coding potential of the rarer of the two cDNAs ...
... (AF052570), suggesting a possible role for this sequence in the negative regulation of C-function gene expression (Figure 1B). Two types of FAR cDNA were identified in the cDNA library at different frequencies. The DNA sequence and predicted amino acid-coding potential of the rarer of the two cDNAs ...
Prof. Kamakaka`s Lecture 12 Notes
... Most mutations are harmful in their effects; only rarely are mutations beneficial. A gene with one wild-type allele is monomorphic; a gene with two or more wild-type alleles is polymorphic. The vast majority of traits are determined by alleles of more than one gene. This means that most traits are ...
... Most mutations are harmful in their effects; only rarely are mutations beneficial. A gene with one wild-type allele is monomorphic; a gene with two or more wild-type alleles is polymorphic. The vast majority of traits are determined by alleles of more than one gene. This means that most traits are ...
Gene Ontology (GO) Tutorial
... MGI includes both. Occasionally, one will come across gene products that have been annotated to Process, Function, and/or Component Unknown. These three terms are used when a curator has looked over the available literature and has found that none of it is adequate to assign a term. A good example i ...
... MGI includes both. Occasionally, one will come across gene products that have been annotated to Process, Function, and/or Component Unknown. These three terms are used when a curator has looked over the available literature and has found that none of it is adequate to assign a term. A good example i ...
COAGULATION AND TRANSFUSION MEDICINE Original Article
... while the patient's factor V L e i d e n genotype is determined by the Molecular Diagnostic Laboratory. If the normalized ratio is greater than 0.85, the p a t i e n t does not have APCR, a n d a coagulation workup for other causes of thrombophilia continues. This w o r k u p includes platelet sizin ...
... while the patient's factor V L e i d e n genotype is determined by the Molecular Diagnostic Laboratory. If the normalized ratio is greater than 0.85, the p a t i e n t does not have APCR, a n d a coagulation workup for other causes of thrombophilia continues. This w o r k u p includes platelet sizin ...
No Slide Title
... • Imprinted genes are expressed differently depending on whether they are inherited through the maternal or paternal parent. ...
... • Imprinted genes are expressed differently depending on whether they are inherited through the maternal or paternal parent. ...
ACTIN-RELATED PROTEIN6 Regulates Female Meiosis By
... been identified in Arabidopsis thaliana (March-Díaz and Reyes, 2009; Meagher et al., 2009), indicating that Arabidopsis has the SWR1 complex. Additionally, H2A.Z deposition at many target loci is disrupted in Arabidopsis SWR1 subunit-defective mutants (Deal et al., 2007). ACTIN-RELATED PROTEIN6 (ARP6 ...
... been identified in Arabidopsis thaliana (March-Díaz and Reyes, 2009; Meagher et al., 2009), indicating that Arabidopsis has the SWR1 complex. Additionally, H2A.Z deposition at many target loci is disrupted in Arabidopsis SWR1 subunit-defective mutants (Deal et al., 2007). ACTIN-RELATED PROTEIN6 (ARP6 ...
Functional Diversiication within the Family of B
... METABOLISM-INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 is controlled by several growth regulatory signals including light and the phytohormones auxin, cytokinin, and gibberellin. To date, GNC and GNL have been attributed functions in the control of germination, greening, flowe ...
... METABOLISM-INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 is controlled by several growth regulatory signals including light and the phytohormones auxin, cytokinin, and gibberellin. To date, GNC and GNL have been attributed functions in the control of germination, greening, flowe ...
Isolation, Characterization and Complementation
... JCB203, but although both of these lesions were reported to map in the crp-cysG region of the E. coli chromosome, data for co-transduction with aroB+ suggest that they might be defective in different genes (compare Cole et al., 1980, with Abou-Jaoudk et al., 19796). To resolve this point a systemati ...
... JCB203, but although both of these lesions were reported to map in the crp-cysG region of the E. coli chromosome, data for co-transduction with aroB+ suggest that they might be defective in different genes (compare Cole et al., 1980, with Abou-Jaoudk et al., 19796). To resolve this point a systemati ...
Histological classification and molecular genetics of meningiomas
... Another well-defined cause in those with young onset and no sex predilection is neurofibromatosis type 2 (NF2). Meningiomas (besides schwannomas) are hallmark features of this autosomal dominant disorder caused by germline mutations in the NF2 gene on chromosome 22q12.6 There are only a few families w ...
... Another well-defined cause in those with young onset and no sex predilection is neurofibromatosis type 2 (NF2). Meningiomas (besides schwannomas) are hallmark features of this autosomal dominant disorder caused by germline mutations in the NF2 gene on chromosome 22q12.6 There are only a few families w ...
PDF - Blood Journal
... decomposition method.41-43 Meff was 172 in our study and hence a P value of less than .001 was required for significance. To avoid losing power to detect true signals because of loss of data, comparisons were focused on maintenance dose rather than on stable maintenance dose. LD was visualized using ...
... decomposition method.41-43 Meff was 172 in our study and hence a P value of less than .001 was required for significance. To avoid losing power to detect true signals because of loss of data, comparisons were focused on maintenance dose rather than on stable maintenance dose. LD was visualized using ...
Leukaemia Section 3q rearrangements in myeloid malignancies Atlas of Genetics and Cytogenetics
... Often associated with young age at diagnosis, trilineage dysplasia, dysmegakaryopoiesis and prior treatment with alkylating agents. ...
... Often associated with young age at diagnosis, trilineage dysplasia, dysmegakaryopoiesis and prior treatment with alkylating agents. ...
Document
... autosomal recessive disorder, which means the defective gene is located on an autosome, and two copies of the defective gene - one from each parent - are required to inherit the disorder. The parents of an individual with an autosomal recessive disorder both carry one copy of the defective gene, but ...
... autosomal recessive disorder, which means the defective gene is located on an autosome, and two copies of the defective gene - one from each parent - are required to inherit the disorder. The parents of an individual with an autosomal recessive disorder both carry one copy of the defective gene, but ...