Genetic polymorphisms among C57BL/6 mouse inbred strains
... different substrains as identical (and commonly refer to these as ‘‘C57’’ or ‘‘C57 black’’ or ‘‘B6’’), it is important to distinguish the exact background when examining the genotype because of the possible effects on phenotype. Thus, knockout and transgenic mice produced in C57BL/6J and C57BL/6N in ...
... different substrains as identical (and commonly refer to these as ‘‘C57’’ or ‘‘C57 black’’ or ‘‘B6’’), it is important to distinguish the exact background when examining the genotype because of the possible effects on phenotype. Thus, knockout and transgenic mice produced in C57BL/6J and C57BL/6N in ...
VAAST 2 User`s Guide
... The GFF3 (General Feature Format version 3) file format is a widely used format for annotating genomic features. Although various versions of GTF and GFF formats have been in use for many years, ...
... The GFF3 (General Feature Format version 3) file format is a widely used format for annotating genomic features. Although various versions of GTF and GFF formats have been in use for many years, ...
TRANSLOCATIONS INVOLVING T H E THIRD AND THE FOURTH
... 1923), a section of the second chromosome carrying the genes from plexus to speck was broken off and became permanently attached to the third chromosome near the gene ebony. Flies heterozygous for the translocation, that is, carrying one deficient second chromosome and one third chromosome with the ...
... 1923), a section of the second chromosome carrying the genes from plexus to speck was broken off and became permanently attached to the third chromosome near the gene ebony. Flies heterozygous for the translocation, that is, carrying one deficient second chromosome and one third chromosome with the ...
Unipro UGENE Manual
... Explanation of the tip above: Some tools are embedded into UGENE as external. To be launched from the UGENE graphical interface, an external tool needs a corresponding executable file. The list of the external tools can be found on this page. The standard package does not include the tools, whereas ...
... Explanation of the tip above: Some tools are embedded into UGENE as external. To be launched from the UGENE graphical interface, an external tool needs a corresponding executable file. The list of the external tools can be found on this page. The standard package does not include the tools, whereas ...
Unipro UGENE Manual
... Explanation of the tip above: Some tools are embedded into UGENE as external. To be launched from the UGENE graphical interface, an external tool needs a corresponding executable file. The list of the external tools can be found on this page. The standard package does not include the tools, whereas ...
... Explanation of the tip above: Some tools are embedded into UGENE as external. To be launched from the UGENE graphical interface, an external tool needs a corresponding executable file. The list of the external tools can be found on this page. The standard package does not include the tools, whereas ...
Rfam Documentation
... Our seed alignments are small, curated sets of representative sequences for each family, as opposed to an alignment of all known members. The seed alignment also has as a secondary structure annotation, which represents the conserved secondary structure for these sequences. The ideal basis for a new ...
... Our seed alignments are small, curated sets of representative sequences for each family, as opposed to an alignment of all known members. The seed alignment also has as a secondary structure annotation, which represents the conserved secondary structure for these sequences. The ideal basis for a new ...
Genetics Practice Test
... 55. Western white butterflies that hatch in springtime have more pigment in their wings than those that hatch in summer. The darker wings help the butterflies stay warmer by absorbing more ____________________ than the lighter-colored wings. 56. The characteristics of an organism are determined by ...
... 55. Western white butterflies that hatch in springtime have more pigment in their wings than those that hatch in summer. The darker wings help the butterflies stay warmer by absorbing more ____________________ than the lighter-colored wings. 56. The characteristics of an organism are determined by ...
Product description P018-G1 SHOX-v03 - MRC
... sequence. This exon numbering is different from the SHOX exon numbering in many articles where exon 7 is referred to as exon 6b. P018-G1 probemix content: This SALSA® MLPA® probemix P018 SHOX contains 48 MLPA probes with amplification products between 124 and 503 nt: 26 probes located in the SHOX + ...
... sequence. This exon numbering is different from the SHOX exon numbering in many articles where exon 7 is referred to as exon 6b. P018-G1 probemix content: This SALSA® MLPA® probemix P018 SHOX contains 48 MLPA probes with amplification products between 124 and 503 nt: 26 probes located in the SHOX + ...
Creating order from chaos: epigenome dynamics in
... Flowering plants have strikingly distinct genomes although they contain a similar suite of ...
... Flowering plants have strikingly distinct genomes although they contain a similar suite of ...
The Influence of Anticodon–Codon Interactions and Modified Bases
... tRNAs occur, Grosjean et al. (2010) call this ‘‘sparing strategy 1.’’ There are also cases where a combination of wobbleU and wobble-G tRNAs occurs (‘‘sparing strategy 2’’), and where only the wobble-U tRNA is present (‘‘sparing strategy 3’’). As far as we know, the wobble-C tRNA only pairs with the ...
... tRNAs occur, Grosjean et al. (2010) call this ‘‘sparing strategy 1.’’ There are also cases where a combination of wobbleU and wobble-G tRNAs occurs (‘‘sparing strategy 2’’), and where only the wobble-U tRNA is present (‘‘sparing strategy 3’’). As far as we know, the wobble-C tRNA only pairs with the ...
PROGRAM PROGRAM
... • Novel candidates for host response to BLV infection in Holstein cattle based on genome-wide association study (P. Brym) – 12 min • Comparing gene expression profiles in the mammary glands of high- and low-milkyield Holstein Friesian cows (M. Miller) – 12 min • Association between polymorphisms ...
... • Novel candidates for host response to BLV infection in Holstein cattle based on genome-wide association study (P. Brym) – 12 min • Comparing gene expression profiles in the mammary glands of high- and low-milkyield Holstein Friesian cows (M. Miller) – 12 min • Association between polymorphisms ...
Transvection Is Common Throughout the Drosophila
... cord (VNC) of the Drosophila larva, which contains a segmentally repeating, stereotyped array of stem cells (neuroblasts). Each neuroblast generates a stereotyped lineage that is easily identifiable during late larval life based on the characteristic morphologies of its constituent neurons (Truman et ...
... cord (VNC) of the Drosophila larva, which contains a segmentally repeating, stereotyped array of stem cells (neuroblasts). Each neuroblast generates a stereotyped lineage that is easily identifiable during late larval life based on the characteristic morphologies of its constituent neurons (Truman et ...
Chromosome Variation
... the chromosome has been doubled (see Figure 9.5a). Consider a chromosome with segments AB CDEFG, in which represents the centromere. A duplication might include the EF segments, giving rise to a chromosome with segments AB CDEFEFG. This type of duplication, in which the duplicated region is immediat ...
... the chromosome has been doubled (see Figure 9.5a). Consider a chromosome with segments AB CDEFG, in which represents the centromere. A duplication might include the EF segments, giving rise to a chromosome with segments AB CDEFEFG. This type of duplication, in which the duplicated region is immediat ...
Alternatively Spliced Genes
... of removing intervening sequences (introns) from the nascent transcript (messenger RNA precursor, or pre-mRNA) (as depicted in •Fig. 1). The discovery of split genes in the viral genome and subsequent research in the field of pre-mRNA splicing have greatly advanced our understanding of mammalian gene ...
... of removing intervening sequences (introns) from the nascent transcript (messenger RNA precursor, or pre-mRNA) (as depicted in •Fig. 1). The discovery of split genes in the viral genome and subsequent research in the field of pre-mRNA splicing have greatly advanced our understanding of mammalian gene ...
Array-based sequencing of filaggrin gene for
... The filaggrin gene is a member of the S100 fused-type gene family, a group of genes with a conserved exon structure and likely shared functions in epithelial biology (Gan et al. 1990; Henry et al. 2012; Strasser et al. 2014). FLG transcription is initiated in exon 2 with the majority of the profilag ...
... The filaggrin gene is a member of the S100 fused-type gene family, a group of genes with a conserved exon structure and likely shared functions in epithelial biology (Gan et al. 1990; Henry et al. 2012; Strasser et al. 2014). FLG transcription is initiated in exon 2 with the majority of the profilag ...
Product description P048-C1-0315 LMNA-MYOT - MRC
... muscular dystrophy type 1B (LGMD1B), result from alterations in the LMNA gene, encoding type A-lamins. Pathophysiological mechanisms explaining how mutations in a unique gene could lead to such various phenotypes are still unknown, but probably involve alterations in cellular mechanical stress respo ...
... muscular dystrophy type 1B (LGMD1B), result from alterations in the LMNA gene, encoding type A-lamins. Pathophysiological mechanisms explaining how mutations in a unique gene could lead to such various phenotypes are still unknown, but probably involve alterations in cellular mechanical stress respo ...
Regulatory Motifs in DNA Sequences
... • Examine frequencies of l-tuples, combinations of 2 symbols, 3 symbols, etc. • “The” is the most frequent 3-tuple in English and “;48” is the most frequent 3tuple in the encrypted text • Make inferences of unknown symbols by examining other frequent l-tuples ...
... • Examine frequencies of l-tuples, combinations of 2 symbols, 3 symbols, etc. • “The” is the most frequent 3-tuple in English and “;48” is the most frequent 3tuple in the encrypted text • Make inferences of unknown symbols by examining other frequent l-tuples ...
Metatranscriptome_Pipeline_Tutorial.doc
... the use of the pipeline by going through the various steps to illustrate the complexity of the process and the underlying tools and files used and generated by the pipeline. To illustrate the process we are going to use sequence reads generated from the rumen of a cow. These are 100bp paired end rea ...
... the use of the pipeline by going through the various steps to illustrate the complexity of the process and the underlying tools and files used and generated by the pipeline. To illustrate the process we are going to use sequence reads generated from the rumen of a cow. These are 100bp paired end rea ...
The landscape of Neandertal ancestry in present
... We have shown that interbreeding of Neandertals and modern humans introduced alleles onto the modern human genetic background that were not tolerated and were swept away, in part because they contributed to male hybrid sterility. The resulting reduction in Neandertal ancestry was quantitatively larg ...
... We have shown that interbreeding of Neandertals and modern humans introduced alleles onto the modern human genetic background that were not tolerated and were swept away, in part because they contributed to male hybrid sterility. The resulting reduction in Neandertal ancestry was quantitatively larg ...
Novel pathogen-specific primers for the detection of Agrobacterium
... (SZEGEDI and BOTTKA, 2002). Although an improved virCspecific primer pair detected some A. vitis strains (KAWAGUCHI et al. 2005), comprehensive studies including the various opine groups have not been published. Similarly, the virD2 specific primers (HAAS et al. 1995) detect pathogenic A. tumefaciens ...
... (SZEGEDI and BOTTKA, 2002). Although an improved virCspecific primer pair detected some A. vitis strains (KAWAGUCHI et al. 2005), comprehensive studies including the various opine groups have not been published. Similarly, the virD2 specific primers (HAAS et al. 1995) detect pathogenic A. tumefaciens ...
Notes for Chaper 4 of the Jones/Pevzer book
... • Nucleotides in motifs encode for a message in the “genetic” language. Symbols in “The Gold Bug” encode for a message in English • In order to solve the problem, we analyze the frequencies of patterns in DNA/Gold Bug message. • Knowledge of established regulatory motifs makes the Motif Finding prob ...
... • Nucleotides in motifs encode for a message in the “genetic” language. Symbols in “The Gold Bug” encode for a message in English • In order to solve the problem, we analyze the frequencies of patterns in DNA/Gold Bug message. • Knowledge of established regulatory motifs makes the Motif Finding prob ...
SALSA MLPA probemix P018-F1 SHOX - MRC
... within the PAR1 region (pseudoautosomal region 1) which covers the 3000 kb of the X and Y chromosomes next to the p-telomere. This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are pres ...
... within the PAR1 region (pseudoautosomal region 1) which covers the 3000 kb of the X and Y chromosomes next to the p-telomere. This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are pres ...
SALSA MLPA probemix P222-A2 LCA mix-2 - MRC
... polymorphism in the sequence detected by a probe can also cause a reduction in relative peak area, even when not located exactly on the ligation site! In addition, some probe signals are more sensitive to sample purity and small changes in experimental conditions. Therefore, deletions and duplicatio ...
... polymorphism in the sequence detected by a probe can also cause a reduction in relative peak area, even when not located exactly on the ligation site! In addition, some probe signals are more sensitive to sample purity and small changes in experimental conditions. Therefore, deletions and duplicatio ...
Integrated mapping and characterization of the gene underlying the
... of the Dt subgenome, but the underlying gene has yet to be identified. In this study, we used a combination of targeted association analysis, F2 population-based fine mapping, and comparative sequencing of orthologues to identify a candidate gene underlying the okra leaf trait in G. hirsutum. The o ...
... of the Dt subgenome, but the underlying gene has yet to be identified. In this study, we used a combination of targeted association analysis, F2 population-based fine mapping, and comparative sequencing of orthologues to identify a candidate gene underlying the okra leaf trait in G. hirsutum. The o ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.