Mapping Mendelian Factors Underlying Quantitative ... Using RFLP Linkage Maps Eric
... A small value of k thus implies that the cross must be segregatingfor QTLs with relatively large effects (?%(D/k)), which together account for a substantial proportion of the phenotypic difference and explain a substantial proportion of the genetic variance in the backcross. In other words, WRIGHT'S ...
... A small value of k thus implies that the cross must be segregatingfor QTLs with relatively large effects (?%(D/k)), which together account for a substantial proportion of the phenotypic difference and explain a substantial proportion of the genetic variance in the backcross. In other words, WRIGHT'S ...
A Physical Gene Map of the Bacteriophage P22 Late
... B fragment (9.2 kb) is lost, while the other EcoRI fragments are not cleaved by SaZI. The sum of the sizes of the two new double digestion fragments equals the size of EcoRI B, indicating a single Sal1 site is located in EcoRI B. Because the Sal1 B fragment represents sequences from pat counterclock ...
... B fragment (9.2 kb) is lost, while the other EcoRI fragments are not cleaved by SaZI. The sum of the sizes of the two new double digestion fragments equals the size of EcoRI B, indicating a single Sal1 site is located in EcoRI B. Because the Sal1 B fragment represents sequences from pat counterclock ...
Parallel Evolution of Copy-Number Variation across Continents in
... distance from the equator; that is, if allele A is at higher frequency in Maine, is this allele also at higher frequency in Tasmania? Of the 190 CNVs differentiated in the United States, 65 are also differentiated in the same direction with respect to latitude on both continents (fig. 3a; P < 2.2 ...
... distance from the equator; that is, if allele A is at higher frequency in Maine, is this allele also at higher frequency in Tasmania? Of the 190 CNVs differentiated in the United States, 65 are also differentiated in the same direction with respect to latitude on both continents (fig. 3a; P < 2.2 ...
Further manipulation by centric misdivision of the 1RS.1BL
... Complete chromosomes 1R and 1B were reconstructed in wheat from the centric wheat-rye translocation 1RS.1BL. Three substitutions: 1R(1A), 1R(1B), 1R(1D), and three new centric translocations: 1RS.1AL, 1RS.1BL, 1RS.1DL were produced from the reconstructed chromosome 1R. Each one of these has the same ...
... Complete chromosomes 1R and 1B were reconstructed in wheat from the centric wheat-rye translocation 1RS.1BL. Three substitutions: 1R(1A), 1R(1B), 1R(1D), and three new centric translocations: 1RS.1AL, 1RS.1BL, 1RS.1DL were produced from the reconstructed chromosome 1R. Each one of these has the same ...
Product description P003-D1 MLH1-MSH2-v01 - MRC
... µl SD052 DNA in MLPA experiments is recommended as it can be used to aid in data binning of the peak pattern using Coffalyser.Net software. Binning DNA should never be used as a reference sample in the MLPA data analysis. Neither should it be used in quantification of mutation signals, as for this p ...
... µl SD052 DNA in MLPA experiments is recommended as it can be used to aid in data binning of the peak pattern using Coffalyser.Net software. Binning DNA should never be used as a reference sample in the MLPA data analysis. Neither should it be used in quantification of mutation signals, as for this p ...
The Deletion Stocks of Common Wheat
... in one chromosome, forming a double-arm deletion chromosome (see Figure 3). Chromosome 2B. We established homozygous lines for all 13 deletions in the short arm. They had less vigor but good seed set. All 11 deletions in the long arm were homozygous, but lines 2BL-5, -9, and -11 set less than 10 gra ...
... in one chromosome, forming a double-arm deletion chromosome (see Figure 3). Chromosome 2B. We established homozygous lines for all 13 deletions in the short arm. They had less vigor but good seed set. All 11 deletions in the long arm were homozygous, but lines 2BL-5, -9, and -11 set less than 10 gra ...
Intrauterine Growth Restriction (IUGR)
... Figure4:Structureofthe11p15.5imprintedregion..................................................................39 Figure5:Lifecycleofimprintsandepigeneticreprogramming.................................................41 Figure6:Conversionofunmethylatedcytosinetouracilafterb ...
... Figure4:Structureofthe11p15.5imprintedregion..................................................................39 Figure5:Lifecycleofimprintsandepigeneticreprogramming.................................................41 Figure6:Conversionofunmethylatedcytosinetouracilafterb ...
BT314 Virology
... Although army investigators searched vigorously for the bodies of Nicholas and his family, they found only a few personal effects and a single finger. The Bolsheviks eventually won the revolution and instituted the world’s first communist state. Historians have debated the role that Alexis’s illness ...
... Although army investigators searched vigorously for the bodies of Nicholas and his family, they found only a few personal effects and a single finger. The Bolsheviks eventually won the revolution and instituted the world’s first communist state. Historians have debated the role that Alexis’s illness ...
Introduction to Genetics
... Although army investigators searched vigorously for the bodies of Nicholas and his family, they found only a few personal effects and a single finger. The Bolsheviks eventually won the revolution and instituted the world’s first communist state. Historians have debated the role that Alexis’s illness ...
... Although army investigators searched vigorously for the bodies of Nicholas and his family, they found only a few personal effects and a single finger. The Bolsheviks eventually won the revolution and instituted the world’s first communist state. Historians have debated the role that Alexis’s illness ...
Why are most organelle genomes transmitted maternally?
... genomes of the eukaryotic cell, severe evolutionary consequences arise: (i) Nuclear and organellar genomes differ fundamentally in their genome organization, coding capacity, mutation rate, and phylogeography [3, 4]. (ii) Uniparental transmission of organelles implies the existence of different mati ...
... genomes of the eukaryotic cell, severe evolutionary consequences arise: (i) Nuclear and organellar genomes differ fundamentally in their genome organization, coding capacity, mutation rate, and phylogeography [3, 4]. (ii) Uniparental transmission of organelles implies the existence of different mati ...
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and
... different ‘Candidatus’ species is only recommended if there is an indication that these phytoplasmas clearly represent separate populations, as evidenced by significant differences based on molecular markers other than 16S rDNA, antibody specificity, host range and vector transmission specificity. T ...
... different ‘Candidatus’ species is only recommended if there is an indication that these phytoplasmas clearly represent separate populations, as evidenced by significant differences based on molecular markers other than 16S rDNA, antibody specificity, host range and vector transmission specificity. T ...
Designing synthetic MLPA probes - MRC
... RefSeqGene project or the longest transcript does not necessarily include all exons. If this is the case, look for missing exons in alternative transcripts. Note down the NM_ accession nr of choice for later use. Exon numbering: NG_sequences can be consulted to find the exact exon numbers: http://ww ...
... RefSeqGene project or the longest transcript does not necessarily include all exons. If this is the case, look for missing exons in alternative transcripts. Note down the NM_ accession nr of choice for later use. Exon numbering: NG_sequences can be consulted to find the exact exon numbers: http://ww ...
Genetics Principles And Analysis
... Connection: This Land Is Your Land, This Land Is My Land The Huntington's Disease Collaborative Research Group 1993 A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosome ...
... Connection: This Land Is Your Land, This Land Is My Land The Huntington's Disease Collaborative Research Group 1993 A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosome ...
Emended description of the order Chlamydiales, proposal of
... The current taxonomic classification of Chlamydia is based on limited phenotypic, morphologic and genetic criteria. This classification does not take into account recent analysis of the ribosomal operon or recently identified obligately intracellular organisms that have a chlamydia-like developmenta ...
... The current taxonomic classification of Chlamydia is based on limited phenotypic, morphologic and genetic criteria. This classification does not take into account recent analysis of the ribosomal operon or recently identified obligately intracellular organisms that have a chlamydia-like developmenta ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
... when homozygous (Dickie, 1962; Wolff et al., 1986). Finally, genetic complementation analysis suggests that there are multiple genes close to or within the agouti locus required for embryonic development [(Barsh and Epstein, 1989; Lyon et al., 1985; Russell et al., 1963); reviewed in Siracusa (1991) ...
... when homozygous (Dickie, 1962; Wolff et al., 1986). Finally, genetic complementation analysis suggests that there are multiple genes close to or within the agouti locus required for embryonic development [(Barsh and Epstein, 1989; Lyon et al., 1985; Russell et al., 1963); reviewed in Siracusa (1991) ...
SNP Discovery and Genotyping Workshop (PowerPoint)
... Where do I find SNPs to use in my association studies? (e.g. databases, direct resequencing) 2. SNP Selection: How do I choose SNPs that are informative? (i.e. assessing SNP correlation - linkage disequilibrium) 3. SNP Associations: What analyses can I perform after genotyping these SNPs? (e.g. sing ...
... Where do I find SNPs to use in my association studies? (e.g. databases, direct resequencing) 2. SNP Selection: How do I choose SNPs that are informative? (i.e. assessing SNP correlation - linkage disequilibrium) 3. SNP Associations: What analyses can I perform after genotyping these SNPs? (e.g. sing ...
BIO 402 - National Open University of Nigeria
... factors takes place. His theory was that the alternation of reduction and fertilization is necessary for maintaining constant chromosome numbers for sexual reproduction. At that time this process had not been observed under the microscope, and its mechanism was a matter of speculation. ...
... factors takes place. His theory was that the alternation of reduction and fertilization is necessary for maintaining constant chromosome numbers for sexual reproduction. At that time this process had not been observed under the microscope, and its mechanism was a matter of speculation. ...
A survey on computational methods for enhancer and
... ChIA-PET have facilitated whole-genome identification of DNA regions that are in close proximity in the three-dimensional genome structure but are not necessarily adjacent to each other in the primary DNA sequence, without requiring an input set of candidates. Among these two techniques, ChIA-PET fu ...
... ChIA-PET have facilitated whole-genome identification of DNA regions that are in close proximity in the three-dimensional genome structure but are not necessarily adjacent to each other in the primary DNA sequence, without requiring an input set of candidates. Among these two techniques, ChIA-PET fu ...
Human respiratory mucins Human respiratory Lamblin, J.P.
... these sequences were characterized by the presence of "tandem repeats" of 23 and 17 amino acids, respectively, [33, 34]. In the case of human airway mucins, repetitive sequences of 8 and 16 amino acids were found. These incomplete sequences were not homologous and differed from the sequences describ ...
... these sequences were characterized by the presence of "tandem repeats" of 23 and 17 amino acids, respectively, [33, 34]. In the case of human airway mucins, repetitive sequences of 8 and 16 amino acids were found. These incomplete sequences were not homologous and differed from the sequences describ ...
List of references - UC Davis Plant Sciences
... their use in phylogenetic and fingerprinting analysis. Genome 44:50-62. Austin, S. et al. 1985. Intra-specific fusions in S. tuberosum. TAG 71:172-175. Barandalla L, de Galarreta JIR, Rios D, et al. 2006. Molecular analysis of local potato cultivars from Tenerife island using microsatellite markers. ...
... their use in phylogenetic and fingerprinting analysis. Genome 44:50-62. Austin, S. et al. 1985. Intra-specific fusions in S. tuberosum. TAG 71:172-175. Barandalla L, de Galarreta JIR, Rios D, et al. 2006. Molecular analysis of local potato cultivars from Tenerife island using microsatellite markers. ...
Identity elements in tRNA-mediated transcription
... Fig. 3. Effect of native and chimeric tRNAs on transcription antitermination in the trpE-lacZ fusion. RNA was isolated from L. lactis cells after a growth medium shift as indicated in Methods and used to prepare a Northern blot that was hybridized with a lacZ-specific probe to visualize full length ...
... Fig. 3. Effect of native and chimeric tRNAs on transcription antitermination in the trpE-lacZ fusion. RNA was isolated from L. lactis cells after a growth medium shift as indicated in Methods and used to prepare a Northern blot that was hybridized with a lacZ-specific probe to visualize full length ...
View PDF
... partner had 46,XX,9qh+ karyotype, inferring the increased presence of heterochromatin region in the long arm of one of the chromosome 9. Heterochromatin polymorphisms are microscopically visible regions on chromosomes 1, 9, 16, the distal two thirds of the long arm of the Y chromosome and the satell ...
... partner had 46,XX,9qh+ karyotype, inferring the increased presence of heterochromatin region in the long arm of one of the chromosome 9. Heterochromatin polymorphisms are microscopically visible regions on chromosomes 1, 9, 16, the distal two thirds of the long arm of the Y chromosome and the satell ...
The amelogenin gene
... Mapping of human amelogenin gene loci on the X- and V-chromosomes Lau et al. (1989) mapped human amelogenin genes on the short arm of the X-chromosome in the p22.1-p22.3 region and in the peri centric region of the V-chromosome. The amelogenin sequence on the human V-chromosome was tentatively mappe ...
... Mapping of human amelogenin gene loci on the X- and V-chromosomes Lau et al. (1989) mapped human amelogenin genes on the short arm of the X-chromosome in the p22.1-p22.3 region and in the peri centric region of the V-chromosome. The amelogenin sequence on the human V-chromosome was tentatively mappe ...
Horizontal gene transfer from flowering plants to Gnetum
... other seed plants. They are also characterized by a fournucleotide (GATA) insertion that makes exon b nonfunctional (Fig. 2). The uniqueness of the two types of Gnetum mt nad1 intron 2 sequences precludes contamination as an explanation for our findings. As shown by Gugerli et al. (19) for Gnetum gn ...
... other seed plants. They are also characterized by a fournucleotide (GATA) insertion that makes exon b nonfunctional (Fig. 2). The uniqueness of the two types of Gnetum mt nad1 intron 2 sequences precludes contamination as an explanation for our findings. As shown by Gugerli et al. (19) for Gnetum gn ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.