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THE NERVOUS SYSTEM A. TWO PARTS Central Nervous System(CNS)- brain/spinal cord Peripheral Nervous System(PNS)-nerves through the body 31 pairs of spinal nerves 12 pairs of cranial nerves B. 3 BASIC FUNCTIONS 1. Sensory- gathers info - receptors of PNS send signals to CNS 2. Integrative- info is brought together - interpreted, create sensations, create thoughts, add to memory, make decisions 3. Motor – response to signals (impulses) - Signals sent from CNS to muscles/glands Homeostasis- maintain stable conditions MOTOR: Somatic Nervous System- skeletal muscles Autonomic Nervous System- smooth muscles, glands C. NEURONS-NERVE CELLS Body with many extensions(nerve fibers) that conduct impulses 2 types of processes Dendrites Receive Axons- shorter more numerous input single long fiber Conducts impulse away D. NEUROGLIAL CELLS Support tissue of the nervous system 5 Types 1. Microglial : scattered throughout, digest debris or bacteria 2. Oligodendrocytes: provide insulation around the axons Creates myelin sheath that insulates axons 3. Astrocytes: connect blood vessels to neurons 4. Ependymal Cells: form a membrane that covers brain-like parts 5. Schwann cells: form the insulating sheath around the neurons within the PNS *Myelin Sheaths - necessary for insulation of neurons NEURON STRUCTURE Cell body- contains cellular organelles Neurofibril - fibers- support organelles Chromatophilic substance (rough ER) transport system Myelin -insulation surrounding axons Nodes of Ranvier - gaps in the insulation Synaptic cleft- space between neurons WHITE VS GREY MATTER Myelinated (white matter) – myelinated axons Unmyelinated (grey matter) - unmyelinated ALL NEURONS DO THREE THINGS: 1. Receive a signal. Can be any type of stimulus (change in environment, signal from another neuron, etc). 2. Transmit a signal to another location. Ex: finger touching something • signal to spinal cord or brain. 3. Stimulate another cell Another neuron • transmit signal Muscle • contraction Gland • secretion CLASSIFICATION OF NEURONS Structural - Multipolar Bipolar unipolar Functional - sensory neurons - motor neurons - interneurons Nerve- bundle of nerve fibers Nerve Impulse- weak electric current - series action potential along a nerve SYNAPSE Presynaptic neuron- brings impulse to synapse Postsynaptic neuron- neuron stimulated/inhibited by impulse Synaptic Transmission- signal Axon end- hold neurotransmitter NEUROTRANSMITTERS Excitatory - increase membrane permeability, increases chance for threshold to be achieved Inhibitory - decrease membrane permeability, decrease chance for threshold to be achieved Synaptic Transmission Dendrite cell body axon synapse STEPS 1. 2. 3. 4. 5. 6. 7. 8. Neuron membrane maintains resting potential Threshold stimulus is received Sodium channels open Sodium ions diffuse inward, depolarizing the membrane Potassium channels open Potassium ions diffuse outward, repolarizing membrane Resulting action potential causes a local bioelectric current that stimulates adjacent portions of membrane Wave of action potentials travel the length of the axon as a nerve impulse http://highered.mcgrawhill.com/sites/0072495855/student_view0/ch apter14/animation__the_nerve_impulse.html http://outreach.mcb.harvard.edu/animations/ actionpotential.swf TYPES OF NEUROTRANSMITTERS Acetylcholine - stimulates muscle contraction Monoamines - Norepinephrine & Dopamine (sense of feeling good, low levels = depression) Serotonin (sleepiness) Endorphins (reduce pain, inhibit receptors) DRUGS THAT AFFECT NEUROTRANSMITTERS Curare Strychnine Cocaine, morphine, alcohol, ether and chloroform Mescaline and LSD Ecstasy ANTIDEPRESSANTS Zoloft is part of a class of drugs called selective serotonin reuptake inhibitors, or SSRIs for short. SSRIs act on a specific chemical within the brain known as serotonin. This is one of several chemicals used to send messages from one nerve cell to another. IMPULSE PROCESSING Neuronal pool- Groups of neurons making synaptic connections to perform a common function TYPES OF NERVES Sensory Nerves - conduct impulses into the brain or spinal cord Motor Nerves - carry impulses to muscles of glands Mixed Nerves - contain both sensory and motor nerves NERVE PATHWAYS ReceptorDetects stimulus Sensory/Afferent Neuron Central Nervous System- processes information Muscle or Glandreacts Motor/Efferent Neuron NERVE PATHWAYS Reflex Arc- simple pathway, includes few neurons Reflex- simplest response Reflex Behavior- automatic, subconscious response to stimuli Sneezing, heart beat, vomiting, digestion Knee-jerk reflex- stimulus knee- sensory nervespinal cord-motor nerve Withdrawal reflex- occurs when you touch something painful http://www.intelligencetest.com/reflex/index.ht m CENTRAL NERVOUS SYSTEM Brain = cranial cavity spinal cord= vertebral canal Protection= Mengines- membranes located between bone and soft tissue of nervous system MENINGES- 3 LAYERS Dura mater- outermost layer, blood vessels, nerves Arachnoid mater- no blood vessels, inbetween layer Pia mater- inner layer, contains many nerves and blood vessels to nourish cells LAYER OF DURA MATER Cerebrospinal fluid= between arachnoid and pia maters SPINAL CORD Nerve column, passes from brain down through vertebral canal 31 segments – each with a pair of spinal nerves Spinal nerves- branch to various body parts Cervical enlargement- supplies nerves to upper limbs (neck) Lumbar enlargement- lower back, supplies nerves to lower limbs FUNCTION OF SPINAL CORD Conduct impulses, serves as center for reflexes Ascending tracts= carry sensory info to brain Descending tracts= carry motor impulses from the brain to muscles/glands Spinal reflexes- reflex arcs pass through the spinal cord BRAIN Cerebrum – largest, sensory and motor functions, higher mental function (memory, reasoning) Cerebellum – coordinate voluntary muscles Brain stem – regulate visceral functions Balance and Coordination STRUCTURES OF THE CEREBRUM 1. Cerebral hemispheres- mirror images 2. Corpus callosum- nerve fibers that connect hemispheres 3.CONVOLUTIONS OF THE BRAIN Wrinkles and Grooves of the brain gyri- ridges on brain Sulcus- deep grooves Fissure- very deep groove 4. FISSURES Longitudinal fissure - separate right and left sides Transverse fissure- Separates cerebrum from cerebellum Lateral fissure- separates the temporal lobe from the Frontal and Parietal lobes LOBES OF THE BRAIN 5. Frontal – reasoning, thinking, language 6. Parietal – touch, pain, relation of body parts (somatosensory) 7. Temporal Lobe – hearing 8. Occipital – vision 9. Cerebral Cortex - thin layer of gray matter that is the outermost portion of cerebrum (the part with all the wrinkles) FUNCTIONAL AREAS OF BRAIN 1. Motor- controls voluntary movements - the right side of the brain generally controls the left side of the body -also has Broca's Area (speech) 2. Sensory Area-involved in feelings and sensations (visual, auditory, smell, touch, taste) Sensory Homunculus This model shows what a man's body would look like if each part grew in proportion to the area of the cortex of the brain concerned with its sensory perception. 3. Association Areas- higher levels of thinking, interpreting and analyzing information BRAIN STEM- 3 PARTS Midbrain – visual reflexes, eye movements Pons - relay sensory information Medulla Oblongata– heart, respiration, blood pressure Diencephalon 1. Hypothalamus – regulates hormones, heart rate, blood pressure, body temp, hunger, sleep 2. Thalamus - relay station Optic Tract / Chiasma - optic nerves cross over each other MEMORY: HIPPOCAMPUS Memory is controlled by the HIPPOCAMPUS The hippocampus plays a major role in forging memories. EMOTIONS: LIMBIC SYSTEM The prefrontal lobe and the hippocampus are part of a system of structures in the brain. The LIMBIC SYSTEM also includes olfactory lobes. Therefore, memory, emotion, and smell are linked. Crayolas are created today with the same scent because it reminds people of their happy times in childhood. Why is the brain formed so that smell and emotions are tied together? Because pheromones are tied to emotions and behavior, so they need the link. MEMORY We used to classify memory as being long-term or short-term. The new classification is four memory systems that process information for storage and retrieval: Episodic, Semantic, Procedural, and Working. EPISODIC Involved in remembering personal experiences, such as a phone conversation you had yesterday or the movie you watched last week. SEMANTIC Manages the storage and retrieval of general knowledge of facts, such as the number of days in a year or the colors in a rainbow. People with problems in this system may have difficulty in naming an object or describing a named object. Semantic Memory Tasks 1. What month comes after October? 2. Where do Kangaroos live? 3. What actor played the Joker in the last Batman movie? PROCEDURAL Allows us to learn activities and skills that will then be performed automatically with little or no conscious thought. Examples are riding a bicycle or driving a car. Problems with this system leads to loss of skills or significant difficulties in learning new skills. WORKING Governs attention, concentration, and short-term retention. Problems here can impair her a person's ability to pay attention or to accomplish multi-step tasks. Working Memory Tasks 1. Labeling a skeleton (remember that chapter?) 2. Describing the parts of the brain. 3. List all the things you ate yesterday. Test Working Memory PHINEAS GAGE