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Transcript
C48 Nervous System
C48 & C49.2 Nervous System
Nervous system & endocrine system interact to regulate internal body
functions and behavior. Endocrine may take minutes to days;
neurons act 150 m/sec or > 330 mph.
Combination of electrical and chemical signals allow nerve cells
(neurons) to communicate with one another.
3 overlapping functions of nervous system:
 Sensory input – signals from sensory receptors via sensory
neurons, ex. light-detecting cells in eyes
 Integration – interpreting signals and forming responses
(carried out by central nervous system (CNS), brain and spinal
cord in vertebrates) via interneurons
 Motor input – conduction of signal from CNS to effector cells,
ex. muscle or gland cells that carry out responses via motor
neurons
Reflex – automatic response uses only sensory and motor neurons.
Nerves – signal conducting, ropelike bundles of neurons wrapped in
connective tissue.
Peripheral nervous system (PNS) – nerves that communicate
motor and sensory signals between CNS and rest of body.
2 classes of nervous system cells:
 Neurons – conduct messages, functional unit of nervous
system, vary depending on function.
 Glia or supporting cells – more numerous than neurons;
provide structure in nervous system, protect, insulate, and
assist.
Features of neurons:
 Cell body – contains nucleus and other organelles
 Processes – increase distance over which cells can conduct
o Dendrites – convey signal from tips to cell body
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C48 Nervous System
o Axons – conduct signals toward tips, away from cell body;
may be very long, in humans >1 m from spine to foot
 Myelin sheath – insulating layer of many axons
 Synaptic terminals – specialized endings of the axons which
relay signals to other cells by releasing neurotransmitters
(chemical messengers).
 Synapse – junction between neurons or to a muscle or gland
cell.
Membrane potential – voltage measured across the plasma
membrane from differences in ion concentrations from cell’s contents
(-) and the fluid around cell (+). Maintained by different ion
permeabilities and the Na+/K+ pump.
Neurotransmitters can produce different effects on different types of
cells. See p1059. Gas molecules like nitric oxide (NO) can be local
regulators.
Organization of nervous systems: see p. 1065
Nerve net – system of branching nerves throughout body, ex. hydra.
Cephalization – concentration of feeding organs, sensors, and
neural structures on anterior end.
Nerve cord – thick bundle of nerves usu. extending longitudinally
through body from brain.
Vertebrate CNS:
White matter – axons in CNS in bundle with white myelin sheaths.
Gray matter – mainly nerve cell bodies, dendrites, and unmyelinated
axons.
Cerebrospinal fluid (CSF) – formed in brain by blood filtration;
transports nutrients, hormones, and WBC’s across blood-brain
barrier. Acts as shock absorber.
Blood-brain barrier – specialized capillary arrangement that restricts
passage of most substances into the brain, preventing dramatic
fluctuations.
Meninges – layers of connective tissue that protect brain and spinal
cord.
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C48 Nervous System
Brain:
(Parts originate from these basic parts)
Forebrain:
 Cerebrum – has 2 hemispheres (gray & white)
important in planning and learning movements.
o Cerebral cortex – convoluted outer
area AKA neocortex (in mammals)
o Corpus callosum – (thick band of
axons) provides communication
between right and left hemispheres.
 Thalamus – an integrating center to cerebral cortex
 Hypothalamus – maintains homeostasis, especially
in coordinating endocrine & nervous systems;
secretes hormones of posterior pituitary & factors
that regulate the anterior pituitary.
 Pituitary gland – endocrine gland at base of
hypothalamus, releases (oxytocin & ADH) produced
by hypothalamus & secretes many hormones that
regulate diverse body functions (growth hormone,
prolactin, FSH, LH, TSH, Adrenocorticotropic
hormone).
Midbrain – sensory integrating and & relay centers to cerebrum
Hindbrain:
 Pons – breathing control center & relay between
PNS and higher brain.
 Medulla oblongata – breathing, heart & blood
vessel activity, swallowing, digestion, and vomiting
as well as a relay between PNS and higher brain.
 Cerebellum – functions in unconscious
coordination of movement & balance (not really part
of hindbrain as an adult).
Emotions – Although other areas of the brain are involved, the
limbic system is central to emotions. The limbic system includes the
amygdala, hippocampus, and parts of the thalamus which have
diverse functions including emotion, motivation, olfaction, behavior,
and memory. Hippocampus important in memory/learning.
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