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TALK WITH YOUR GROUP ABOUT ALL THE DIFFERENCES YOU SEE BETWEEN DNA AND RNA STRUCTURES… • RNA structure differs from DNA structure in three ways. #1 RNA is single stranded—it looks like one-half of a zipper— whereas DNA is double stranded. #2 • The sugar in RNA is ribose; • REMEMBER: DNA’s sugar is deoxyribose. Ribose #3 • Finally, both DNA and RNA can contain four nitrogenous bases, BUT RNA does not have Thymine. • Thymine is replaced by a similar base called uracil (U). DNA - boss with instructions RNA - workers that take the instructions from the boss to the site to carry out the job. • DNA provides mRNA with the instructions for making the proteins. • RNA takes the copy of instructions to the ribosome • The instructions are a code for how the protein should be assembled (amino acid by amino acid) Chargaff’s Rule • One of the puzzling facts about DNA was a curious relationship between its nucleotides. • Erwin Chargaff (an American biochemist) had discovered that the percentages of guanine and cytosine bases are almost always equal in any sample of DNA.