Selective Crossover Using Gene Dominance as an Adaptive
... Since the emergence of the evolutionary computing, many new natural genetic operators have been research and within genetic algorithms and many new recombination techniques have been proposed. There has been substantially less development in Genetic Programming compared with Genetic Algorithms. Koza ...
... Since the emergence of the evolutionary computing, many new natural genetic operators have been research and within genetic algorithms and many new recombination techniques have been proposed. There has been substantially less development in Genetic Programming compared with Genetic Algorithms. Koza ...
Yeast Supplemental Material
... acid the bacterial population can be significantly reduced. These methods are typically used either in an emergency or as a routine to keep the yeast free from bacteria. Many different acids can be used, but tartaric and phosphoric are most common. The pH of the slurry is adjusted to 2.0-2.4 for 45 ...
... acid the bacterial population can be significantly reduced. These methods are typically used either in an emergency or as a routine to keep the yeast free from bacteria. Many different acids can be used, but tartaric and phosphoric are most common. The pH of the slurry is adjusted to 2.0-2.4 for 45 ...
Imposition of Crossover Interference through the
... along chromosomes such that two COs seldom occur close together, a phenomenon known as CO interference. We have used genetic and cytological methods to investigate interference mechanisms in budding yeast. Assembly of the synaptonemal complex (SC) initiates at a few sites along each chromosome, trig ...
... along chromosomes such that two COs seldom occur close together, a phenomenon known as CO interference. We have used genetic and cytological methods to investigate interference mechanisms in budding yeast. Assembly of the synaptonemal complex (SC) initiates at a few sites along each chromosome, trig ...
XTalkDB: a database of signaling pathway crosstalk
... i) Select two pathways to be queried (referred to as ‘A’ and ‘B’). For every such selection, there are two ordered pairs: (A, B) and (B, A). Note that the crosstalk from A → B is different from crosstalk from B → A. ii) We searched PubMed for publications that may provide evidence for crosstalk betw ...
... i) Select two pathways to be queried (referred to as ‘A’ and ‘B’). For every such selection, there are two ordered pairs: (A, B) and (B, A). Note that the crosstalk from A → B is different from crosstalk from B → A. ii) We searched PubMed for publications that may provide evidence for crosstalk betw ...
Defining characteristics of Tn5 Transposase non
... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
selection for recombination in small populations
... 1 s)2 1 e for the 22, 1 2, 21, and 11 haplotypes, respectively. Epistasis, in this model, is measured by e. Although this model of epistasis is natural for haploids, in diploids, it allows for interactions only among gene products encoded on the same chromosome and not on its homologue. Nevertheless ...
... 1 s)2 1 e for the 22, 1 2, 21, and 11 haplotypes, respectively. Epistasis, in this model, is measured by e. Although this model of epistasis is natural for haploids, in diploids, it allows for interactions only among gene products encoded on the same chromosome and not on its homologue. Nevertheless ...
meme
... present in all of the sequences. * anr — Any Number of Repetitions MEME assumes each sequence may contain any number of non-overlapping occurrences of each motif. This option is useful when you suspect that motifs repeat multiple times within a single sequence. In that case, the motifs found will be ...
... present in all of the sequences. * anr — Any Number of Repetitions MEME assumes each sequence may contain any number of non-overlapping occurrences of each motif. This option is useful when you suspect that motifs repeat multiple times within a single sequence. In that case, the motifs found will be ...
![arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007](http://s1.studyres.com/store/data/014946021_1-c477dba1add7a260e278ca181f537c79-300x300.png)
arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007
... the strand (Vesnaver and Breslauer, 1991), ionic conditions (Dewey and Turner, 1979), and other environmental factors (Freier et al., 1981). The effect of secondary structure has already been seen in the ionic currents through nanopores (Akeson et al., 1999; Meller et al., ...
... the strand (Vesnaver and Breslauer, 1991), ionic conditions (Dewey and Turner, 1979), and other environmental factors (Freier et al., 1981). The effect of secondary structure has already been seen in the ionic currents through nanopores (Akeson et al., 1999; Meller et al., ...
Analysis of clones carrying repeated DNA sequences in two YAC
... First, a set of overlapping cosmid clones has been assembled into 750 contigs covering 90-95% of the genome (Hauge et a/., 1991). Second, efforts are underway to construct overlapping YAC contigs for the five Arabidopsis chromosomes. The three YAC libraries commonly in use are the EG (Grill and Some ...
... First, a set of overlapping cosmid clones has been assembled into 750 contigs covering 90-95% of the genome (Hauge et a/., 1991). Second, efforts are underway to construct overlapping YAC contigs for the five Arabidopsis chromosomes. The three YAC libraries commonly in use are the EG (Grill and Some ...
Downloaded - Laboratoire de Chimie Théorique
... Zn2+, Co2+, Cr2+, Cu2+, Mn2+ and Ni2+. In all cases the initial structure was taken from our previous study (see Methods section).27 We assume that the coordination mode is similar for all cations in both binding sites. The re-optimized structures for Mg2+ and Mn2+ show differences of less than 0.1 A ...
... Zn2+, Co2+, Cr2+, Cu2+, Mn2+ and Ni2+. In all cases the initial structure was taken from our previous study (see Methods section).27 We assume that the coordination mode is similar for all cations in both binding sites. The re-optimized structures for Mg2+ and Mn2+ show differences of less than 0.1 A ...
Kinds of gene rearrangement
... The hypotheses A successful hypothesis is normally based on zlerae causae (ascertained facts), while unsuccessful hypotheses are often marked by containing one or more jictae causae (imagined statements). The first hypothesis as to crossing over seems to have been that of JANSSENS (1909), who predic ...
... The hypotheses A successful hypothesis is normally based on zlerae causae (ascertained facts), while unsuccessful hypotheses are often marked by containing one or more jictae causae (imagined statements). The first hypothesis as to crossing over seems to have been that of JANSSENS (1909), who predic ...
rec-mediated recombinational hot spot activity in bacteriophage
... are termed “hot spot survey crosses.” These crosses are carried out using conditions which block nearly all DNA synthesis (MCMILINand Russo 1972). Though there is some residual DNA synthesis, which is potentially very interesting (J. SIEGEL,nianuscript in preparation), it is convenient and justifiab ...
... are termed “hot spot survey crosses.” These crosses are carried out using conditions which block nearly all DNA synthesis (MCMILINand Russo 1972). Though there is some residual DNA synthesis, which is potentially very interesting (J. SIEGEL,nianuscript in preparation), it is convenient and justifiab ...
Persistence and Loss of Meiotic Recombination
... extending a variable distance into the flanking DNA. The free 3⬘ ends created by the degradation then trigger gap repair by base pairing with complementary sequences of one of the two homologous chromatids; strands of this chromatid act as templates for resynthesis of the degraded strands. This crea ...
... extending a variable distance into the flanking DNA. The free 3⬘ ends created by the degradation then trigger gap repair by base pairing with complementary sequences of one of the two homologous chromatids; strands of this chromatid act as templates for resynthesis of the degraded strands. This crea ...
Distortion of quantitative genomic and expression
... Strategies to mitigate variability in the results obtained from replicate studies have focused on standardizing technical factors, such as array production, RNA synthesis, labeling, hybridization, scanning and data analysis (6–8). Zakharkin et al. (9) suggest that biological differences among sample ...
... Strategies to mitigate variability in the results obtained from replicate studies have focused on standardizing technical factors, such as array production, RNA synthesis, labeling, hybridization, scanning and data analysis (6–8). Zakharkin et al. (9) suggest that biological differences among sample ...
Genetic Analysis of Variation in Human Meiotic Recombination
... [14] collections to determine recombination phenotypes. For our analysis, we used the genotype data from members of twogeneration families that have two or more children to infer recombination phenotypes of the parents in these families. The 511 AGRE families have an average of 2.26 children (median ...
... [14] collections to determine recombination phenotypes. For our analysis, we used the genotype data from members of twogeneration families that have two or more children to infer recombination phenotypes of the parents in these families. The 511 AGRE families have an average of 2.26 children (median ...
paper - Université de Namur
... understand the X-ray images of DNA. However the use of the CCV theory for its originally intended purpose [3], namely for the interpretation of X-ray diffraction by protein α-helices, is a bit too advanced and will not be pursued in the present didactic paper (a recent review [4] covers this and fur ...
... understand the X-ray images of DNA. However the use of the CCV theory for its originally intended purpose [3], namely for the interpretation of X-ray diffraction by protein α-helices, is a bit too advanced and will not be pursued in the present didactic paper (a recent review [4] covers this and fur ...
2 SINGLE-MOLECULE DNA:PROTEIN INTERACTIONS - VU-dare
... Substantial effort has been spent in pushing the resolution of optical tweezers to allow one of the most elementary events in molecular biology, the stepping of a polymerase enzyme over a single base pair, to be resolved in real time. However, what are the ultimate limits of optical tweezers and wha ...
... Substantial effort has been spent in pushing the resolution of optical tweezers to allow one of the most elementary events in molecular biology, the stepping of a polymerase enzyme over a single base pair, to be resolved in real time. However, what are the ultimate limits of optical tweezers and wha ...
Graph-based Methods for the Design of DNA - TUBdok
... DNA computing is a rapidly evolving field utilizing DNA molecules instead of silicon-based electronic units to perform calculations. The reliability of such computations strongly depends on the DNA sequences that represent units of information. Recently, the thermodynamic constraints, based on the f ...
... DNA computing is a rapidly evolving field utilizing DNA molecules instead of silicon-based electronic units to perform calculations. The reliability of such computations strongly depends on the DNA sequences that represent units of information. Recently, the thermodynamic constraints, based on the f ...
Evidence that MEK1 positively promotes
... poles is dependent upon the interhomologue joints mediated by crossovers and sister chromatid cohesion. Without crossovers or sister chromatid cohesion homologue segregation becomes randomized, causing first meiotic non-disjunction. In some organisms the mechanisms ensuring that sufficient DSBs are rep ...
... poles is dependent upon the interhomologue joints mediated by crossovers and sister chromatid cohesion. Without crossovers or sister chromatid cohesion homologue segregation becomes randomized, causing first meiotic non-disjunction. In some organisms the mechanisms ensuring that sufficient DSBs are rep ...
zChap07_140901 - Online Open Genetics
... The recombination events that may be detected will occur during meiosis in the dihybrid individual. If the loci are completely or partially linked, then prior to meiosis, alleles aB will be located on one chromosome, and alleles Ab will be on the other chromosome (based on our knowledge of the genot ...
... The recombination events that may be detected will occur during meiosis in the dihybrid individual. If the loci are completely or partially linked, then prior to meiosis, alleles aB will be located on one chromosome, and alleles Ab will be on the other chromosome (based on our knowledge of the genot ...
Recombination in large RNA viruses: Coronaviruses
... The effects of recombination on the evolution of coronavirus DI RNAs have also been demonstrated.25,28,29 Furthermore, in natural coronavirus infections, recombination also serves as an evolutionary tool. This is particularly evident for IBV, many field isolates of which are recombinants between var ...
... The effects of recombination on the evolution of coronavirus DI RNAs have also been demonstrated.25,28,29 Furthermore, in natural coronavirus infections, recombination also serves as an evolutionary tool. This is particularly evident for IBV, many field isolates of which are recombinants between var ...
24 Recombination Hotspots in Nonallelic Homologous Recombination
... rates can be several orders of magnitude more than in surrounding “cold” regions. In parallel to these developments, sufficient numbers of breakpoints of selected NAHR rearrangements have been characterized at the DNA sequence level to resolve the distribution of crossovers in these cases. This has ...
... rates can be several orders of magnitude more than in surrounding “cold” regions. In parallel to these developments, sufficient numbers of breakpoints of selected NAHR rearrangements have been characterized at the DNA sequence level to resolve the distribution of crossovers in these cases. This has ...
The Rad50 Signature Motif: Essential to ATP Binding and
... The repair of double-strand breaks in DNA is an essential process in all organisms, and requires the coordinated activities of evolutionarily conserved protein assemblies. One of the most critical of these is the Mre11/ Rad50 (M/R) complex, which is present in all three biological kingdoms, but is n ...
... The repair of double-strand breaks in DNA is an essential process in all organisms, and requires the coordinated activities of evolutionarily conserved protein assemblies. One of the most critical of these is the Mre11/ Rad50 (M/R) complex, which is present in all three biological kingdoms, but is n ...
Modes of Selection and Recombination Response in Drosophila
... and scored the testcross offspring for recombinant phenotypes. The data are expressed as a recombination index, representing the observed number of recombination events divided by the total number of possible recombination events. Because each chromosome has three markers, the recombination index is ...
... and scored the testcross offspring for recombinant phenotypes. The data are expressed as a recombination index, representing the observed number of recombination events divided by the total number of possible recombination events. Because each chromosome has three markers, the recombination index is ...
Incorporation of reporter molecule
... analysis (5) and DNA sequencing (6,7). In addition, the catalytic repertoire of nucleic acids can potentially be expanded through incorporation of various functional groups linked to nucleotides followed by selection using the systematic evolution of ligands by exponential enrichment (SELEX) techniq ...
... analysis (5) and DNA sequencing (6,7). In addition, the catalytic repertoire of nucleic acids can potentially be expanded through incorporation of various functional groups linked to nucleotides followed by selection using the systematic evolution of ligands by exponential enrichment (SELEX) techniq ...
Holliday junction
A Holliday junction is a branched nucleic acid structure that contains four double-stranded arms joined together. These arms may adopt one of several conformations depending on buffer salt concentrations and the sequence of nucleobases closest to the junction. The structure is named after the molecular biologist Robin Holliday, who proposed its existence in 1964.In biology, Holliday junctions are a key intermediate in many types of genetic recombination, as well as in double-strand break repair. These junctions usually have a symmetrical sequence and are thus mobile, meaning that the four individual arms may slide though the junction in a specific pattern that largely preserves base pairing. Additionally, four-arm junctions similar to Holliday junctions appear in some functional RNA molecules.Immobile Holliday junctions, with asymmetrical sequences that lock the strands in a specific position, were artificially created by scientists to study their structure as a model for natural Holliday junctions. These junctions also later found use as basic structural building blocks in DNA nanotechnology, where multiple Holliday junctions can be combined into specific designed geometries that provide molecules with a high degree of structural rigidity.