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Anatomy & Physiology Chapter 8: Nervous System Version #1 DO NOT WRITE ON THIS TEST 1. During depolarization (loss in polarization, as when a nerve impulse occurs) (http://video.search.yahoo.com/play;_ylt=A2KIo9cbFMdSknIAoSv7w8QF;_ylu=X3oDMTB2 dGQwNXBoBHNlYwNzcgRzbGsDdmlkBHZ0aWQDVjE1MARncG9zAzU?p=the+process+of+depolarization&vid=f93b27c88bcbf9d30d5146eb957b53ec&l=3%3A24& turl=http%3A%2F%2Fts2.mm.bing.net%2Fth%3Fid%3DV.4926629346018329%26pid%3D1 5.1&rurl=http%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DifD1YG07fB8&tit=Actio n+Potentials&c=4&sigr=11a1n0o4b&sigt=10hhmcj4f&age=0&fr=chr-greentree_sf&tt=b) a. The neuron is the nerve cell that characteristically has 3 parts: dendrite (process of a neuron, typically branched that conducts nerve impulses toward the cell body), cell body (portion of a nerve cell that includes a cytoplasmic mass and a nucleus and from which the nerve fibers extend), and axon (process of a neuron that conducts nerve impulses away from the cell body). The video shows the process of depolarization. A. potassium ions move outside the neuron. B. sodium ions move inside the neuron. C. electrons stream along the axon. D. calcium ions move inside the neuron. 2. When a nerve is at its resting potential (the potential energy of a resting neuron created by separating unlike charges across the neuron cell membrane), the inside charge (read paragraph 1 of Resting Potential on p. 158.) is a. negative. b. positive. c. neutral. Revised: 7/22/2008 1 3. Which type of neuron is involved in a reflex arc? (p. 16 of CH. 8 PPT) a. sensory neuron: neuron that takes the nerve impulse to the central nervous system; also known as the afferent neuron b. motor neuron: neuron that takes nerve impulses from the central nervous system to the effector (1. A muscle, gland, or organ capable of responding to a stimulus, especially a nerve impulse.2. A nerve ending that carries impulses to a muscle, gland, or organ and activates muscle contraction or glandular secretion.3. Biochemistry A small molecule that when bound to an allosteric site of an enzyme causes either a decrease or an increase in the activity of the enzyme.) c. interneuron: neuron found within the central nervous system that takes nerve impulses from one portion of the system to another. A. sensory B. motor C. interneuron D. All of the choices are correct. 4. What ion is found on the outside of the neuron membrane that mostly contributes to a positive resting potential? Sodium ions and potassium ions reside on either side of the neuron membranes. Which of those two reside on the outside? The video should be able to explain. A. calcium B. potassium C. sodium D. chloride 5. What do the ventricles (cavity of an organ such as the brain or the heart) of the brain contain? A. meninges: protective membranous coverings around the brain and spinal cord B. dura mater: tough outer layer of the meninges; membranes that protect the brain and spinal cord C. cerebrospinal fluid: fluid found within the ventricles of the brain and surrounding the CNS in association with the meninges D. meninges and dura mater 6. The autonomic nervous system (Hint: When something is autonomous, that means it regulates itself.) A. controls skeletal muscle contractions. B. controls actions of the internal viscera. C. controls release of secretions from glands. D. both controls actions of the internal viscera and controls release of secretions from glands are correct. 7. What protects the spinal cord? (Hint: Name the parts of the spine.) A. vertebrae: bones of the vertebral column B. meninges: protective membranous coverings around the brain and spinal cord C. cerebrospinal fluid: fluid within the ventricles of the brain and surrounding the CNS in association with the meninges D. All of the choices are correct. Revised: 7/22/2008 2 8. Which part of a neuron carries impulse away from the cell body? A. axon: process of a neuron that conducts nerve impulses away from the cell body B. dendrite: process of a neuron, typically branched, that conducts nerve impulses toward the cell body C. nucleus: large organelle that contains the chromosomes and acts as a cell control center D. neuroglia: nonconducting nerve cells that are intimately association with neurons and function in a supportive capacity; to see how these cells function and their types, please visit: http://www.interactive-biology.com/3583/neuroglia-the-army/ 9. Which of the following is NOT served by the somatic sensory division of the PNS? (Hint: Imagine your body and its parts. What parts can feel beyond the limits of your body?) A. stomach B. skeletal muscles C. special senses D. skin 10. A sensory neuron carries impulses (Hint: Think of a military outpost in Iraq. An enemy attacks that outpost. How does that outpost respond?) A. to muscles and glands. B. to the CNS. C. always within the CNS. Revised: 7/22/2008 3 11. What flows across the synaptic cleft (small gap between the synaptic knob on one neuron and the dendrite on another neuron)? A. sodium ions (Sodium ions (often referred to as just "sodium") are necessary for regulation of blood and body fluids, transmission of nerve impulses, heart activity, and certain metabolic functions. Sodium ions play a diverse and important role in many physiological processes. Excitable animal cells, for example, rely on the entry of Na+ to cause a depolarization. An example of this is signal transduction in the human central nervous system, which depends on sodium ion motion across the nerve cell membrane, in all nerves.) B. electrons (the small, negatively charged particle that revolves around the nucleus of an atom) C. a neurotransmitter (chemical made at the end of axons (process of a neuron that conducts nerve impulses away from the cell body) that is responsible for transmission across a synapse) D. potassium ions (Potassium is the eighth or ninth most common element by mass (0.2%) in the human body, so that a 60 kg adult contains a total of about 120 g of potassium.[50] The body has about as much potassium as sulfur and chlorine, and only the major minerals calcium and phosphorus are more abundant.[51] Potassium cations are important in neuron (brain and nerve) function, and in influencing osmotic balance between cells and the interstitial fluid, with their distribution mediated in all animals (but not in all plants) by the so-called Na+/K+-ATPase pump.[52] This ion pump uses ATP to pump three sodium ions out of the cell and two potassium ions into the cell, thus creating an electrochemical gradient over the cell membrane. In addition, the highly selective potassium ion channels (which are tetramers) are crucial for the hyperpolarization, in for example neurons, after an action potential is fired. The most recently resolved potassium ion channel is KirBac3.1, which gives a total of five potassium ion channels (KcsA, KirBac1.1, KirBac3.1, KvAP, and MthK) with a determined structure.[53] All five are from prokaryotic species.) 12. In which direction does the transmission cross a synapse? A. dendrite to axon B. axon to dendrite (Please review your definitions of these terms so that you can remember why!) C. either way D. both ways 13. The lateral ventricles (en.wikipedia.org/wiki/Lateral_ventricles; A diagram is located at this site: http://www.eradiography.net/articles/ctbrain/brainanatomy.htm) are located in the A. cerebrum (main portion of the vertebrate brain that is responsible for consciousness). B. medulla oblongata (lowest portion of the brain; concerned with the control of the central nervous system). C. thalamus (mass of gray matter located at the base of the cerebrum in the wall of the third ventricle; receives sensory information and selectively passes it to the cerebrum). D. cerebellum (the part of the brain that controls muscular coordination). Revised: 7/22/2008 4 14. There are ____ pairs of cranial nerves and ____ pairs of spinal nerves. A. 31; 12 B. 12; 31 C. 10; 12 D. 15; 30 15. The spinal cord is part of the ___________, while the cranial nerves (nerve that arises from the brain) are part of the ___________. A. CNS, PNS B. PNS, CNS 16. The primary visual area is located in the ______ lobe. A. frontal (The executive functions of the frontal lobes involve the ability to recognize future consequences resulting from current actions, to choose between good and bad actions (or better and best), override and suppress socially unacceptable responses, and determine similarities and differences between things or events. The frontal lobes also play an important part in retaining longer term memories which are not task-based. These are often memories associated with emotions derived from input from the brain's limbic system. The frontal lobe modifies those emotions to generally fit socially acceptable norms.) B. parietal (Since the function summary is very long, please look here: http://en.wikipedia.org/wiki/Parietal_lobe#Function) C. temporal (http://en.wikipedia.org/wiki/Temporal_lobe) D. occipital (http://en.wikipedia.org/wiki/Occipital_lobe) 17. Which of the following is the correct layering of the meninges from superficial to deep? A. dura mater, pia mater, arachnoid mater B. pia mater, dura mater, arachnoid mater C. dura mater, arachnoid mater, pia mater (http://en.wikipedia.org/wiki/Meninges#Anatomy) D. arachnoid mater, dura mater, pia mater 18. The small gap between two successive neurons is called the A. synaptic cleft. B. axon terminal. (http://en.wikipedia.org/wiki/Axon_terminal) C. dendrite terminal. (http://en.wikipedia.org/wiki/Dendrite) D. neurotransmitter. 19. The interpretation of olfactory (smell) receptor information would fall under which general function of the nervous system? http://encyclopedia.lubopitkobg.com/Human_Nervous_System.html A. sensory input B. motor output C. integration Revised: 7/22/2008 5 20. A stimulus will open ion channels that will allow ________ to flow into the neuron, causing the inside to become______________ charged. (Refer to Question 1 on Depolarization). A. sodium, negatively B. sodium, positively C. potassium, negatively D. potassium, positively 21. The optic nerve is a A. cranial nerve. B. sensory nerve. C. spinal nerve. D. cranial nerve and a sensory nerve. (Read this http://en.wikipedia.org/wiki/Optic_nerve, and tell me the 2 reasons why the optic nerve is both.) 22. The space between the arachnoid and pia maters that is filled with cerebrospinal fluid is the A. dural venous sinus. B. subdural space. C. subarachnoid space. (Sub- means ‘under’.) D. epidural space. 23. The limbic system is concerned with (http://en.wikipedia.org/wiki/Limbic_system) A. relating feelings to experiences. B. our deepest emotions, such as rage and pleasure. C. learning and memory. D. All of these choices are correct. 24. Norepinephrine is a neurotransmitter used by the (http://en.wikipedia.org/wiki/Parasympathetic_nervous_system; http://en.wikipedia.org/wiki/Sympathetic_nervous_system A. parasympathetic nervous system. (regulates the internal organs and glands) B. sympathetic nervous system. (Hint: Adrenaline drives our fight or flight response.) C. both parasympathetic and sympathetic nervous systems. 25. Which of the following is a common neurotransmitter? A. acetylcholine (A white crystalline derivative of choline that is released at the ends of nerve fibers in the somatic and parasympathetic nervous systems and is involved in the transmission of nerve impulses in the body.) B. acetylcholinesterase (An enzyme that breaks down acetylcholine.) C. an enzyme D. acetylcholinesterase and an enzyme Revised: 7/22/2008 6 26. Which area of the brain serves as the sensory relay station for all sensory input except smell? A. hypothalamus (the part of the brain that connects the nervous system to the endocrine system because of its control of the pituitary gland. The hypothalamus is responsible for certain metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes certain neurohormones, often called releasing hormones or hypothalamic hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones. The hypothalamus controls body temperature, hunger, important aspects of parenting and attachment behaviors, thirst,[1] fatigue, sleep, and circadian rhythms. B. pineal gland (The pineal gland, also known as the pineal body, conarium or epiphysis cerebri, is a small endocrine gland in the vertebrate brain. It produces the serotonin derivative melatonin, a hormone that affects the modulation of sleep patterns in the circadian rhythms and seasonal functions.[1][2] Its shape resembles a tiny pine cone (hence its name), and it is located in the epithalamus, near the centre of the brain, between the two hemispheres, tucked in a groove where the two rounded thalamic bodies join. The pineal gland produces melatonin. C. thalamus (The thalamus is perched on top of the brainstem, near the center of the brain, with nerve fibers projecting out to the cerebral cortex in all directions. The medial surface of the thalamus constitutes the upper part of the lateral wall of the third ventricle, and is connected to the corresponding surface of the opposite thalamus by a flattened gray band, the interthalamic adhesion. The thalamus has multiple functions. It may be thought of as a kind of switchboard of information. It is generally believed to act as a relay between a variety of subcortical areas and the cerebral cortex. In particular, every sensory system (with the exception of the olfactory system) includes a thalamic nucleus that receives sensory signals and sends them to the associated primary cortical area. For the visual system, for example, inputs from the retina are sent to the lateral geniculate nucleus of the thalamus, which in turn projects to the primary visual cortex (area V1) in the occipital lobe. The thalamus is believed to both process sensory information as well as relay it—each of the primary sensory relay areas receives strong "back projections" from the cerebral cortex. Similarly the medial geniculate nucleus acts as a key auditory relay between the inferior colliculus of the midbrain and the primary auditory cortex, and the ventral posterior nucleus is a key somatosensory relay, which sends touch and proprioceptive information to the primary somatosensory cortex. The thalamus also plays an important role in regulating states of sleep and wakefulness.[10] Thalamic nuclei have strong reciprocal connections with the cerebral cortex, forming thalamo-cortico-thalamic circuits that are believed to be involved with consciousness. The thalamus plays a major role in regulating arousal, the level of awareness, and activity. Damage to the thalamus can lead to permanent coma. Revised: 7/22/2008 7 D. basal nuclei (More often referred to as basal ganglia, these have a role in motor movements, especially those having to do with the eyes. Basal ganglia connect the cerebral cortex and thalamus to other parts of the brain.) 27. The protective membranes around the brain and spinal cord are the A. ventricles. (The ventricular system is a set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord. The ventricle lining consists of an epithelial membrane called ependyma. The brain and spinal cord are covered by the meninges, (three tough membranes) which protect these organs from rubbing against the bones of the skull and spine. The cerebrospinal fluid (CSF) within the skull and spine is found between the pia mater and the arachnoid mater and provides further cushioning.The CSF that is produced in the ventricular system has four main purposes: buoyancy, protection, chemical stability, and the provision of nutrients necessary to the brain. The protection purpose comes into play with the meninges: pia mater, and the arachnoid mater. The CSF is there to protect the brain from striking the cranium when the head is jolted. CSF provides buoyancy and support to the brain against gravity. The buoyancy protects the brain since the brain and CSF are similar in density; this makes the brain float in neutral buoyancy, suspended in the CSF. This allows the brain to attain a decent size and weight without resting on the floor of the cranium, which would kill nervous tissue.[2][3]) B. meninges. (refer to the definition from earlier) C. serous membranes. (In anatomy, serous membrane (or serosa) is a smooth membrane consisting of a thin layer of cells which secrete serous fluid, and a thin epithelial layer. The Latin anatomical name is tunica serosa. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is entirely different from the adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. The serous membrane covering the heart and lining the mediastinum is referred to as the pericardium, the serous membrane lining the thoracic cavity and surrounding the lungs is referred to as the pleura, and that lining the abdominopelvic cavity and the viscera is referred to as the peritoneum. They secrete a lubricating fluid that reduces friction in muscle movement. D. arbor vitae. (The arbor vitae /ˌɑrbɔr ˈvaɪtiː/ (Latin for "Tree of Life") is the cerebellar white matter, so called for its branched, tree-like appearance. In some ways it more resembles a fern and is present in both cerebellar hemispheres.[1] It brings sensory and motor information to and from the cerebellum. The arbor vitae is located deep in the cerebellum. Situated within the arbor vitae are the deep cerebellar and the fastigial nuclei. It also contains the emboliform-globose and dentate nuclei. These four different structures lead to the efferent projections of the cerebellum.[2]) Revised: 7/22/2008 8 28. The autonomic system that gets the body ready for "fight or flight" is the A. parasympathetic nervous system. B. sympathetic nervous system. C. somatic motor nervous system. 29. A motor neuron carries impulses A. to muscles and glands. B. to the CNS. C. always within the CNS. 30. Which disease is due, in part, to reduced amounts of acetylcholine in the brain? A. Parkinson's disease B. Huntington's disease C. Alzheimer's disease D. All of the choices are correct. 31. The primary somatosensory area is located in the _____ lobe. A. frontal: The executive functions of the frontal lobes involve the ability to recognize future consequences resulting from current actions, to choose between good and bad actions (or better and best), override and suppress socially unacceptable responses, and determine similarities and differences between things or events. The frontal lobes also play an important part in retaining longer term memories which are not task-based. These are often memories associated with emotions derived from input from the brain's limbic system. The frontal lobe modifies those emotions to generally fit socially acceptable norms. Psychological tests that measure frontal lobe function include finger tapping, Wisconsin Card Sorting Task, and measures of verbal and figural fluency.[5] B. parietal (http://en.wikipedia.org/wiki/Parietal_lobe#Function) C. temporal (http://en.wikipedia.org/wiki/Temporal_lobe) D. occipital (The occipital lobe is divided into several functional visual areas. Each visual area contains a full map of the visual world. Although there are no anatomical markers distinguishing these areas (except for the prominent striations in the striate cortex), physiologists have used electrode recordings to divide the cortex into different functional regions. The first functional area is the primary visual cortex. It contains a low-level description of the local orientation, spatial-frequency and color properties within small receptive fields. Primary visual cortex projects to the occipital areas of the ventral stream (visual area V2 and visual area V4), and the occipital areas of the dorsal stream—visual area V3, visual area MT (V5), and the dorsomedial area (DM). 32. Which of the following is part of a neuron? A. axon B. cell body C. dendrite D. all of these are parts of a neuron Revised: 7/22/2008 9 33. Cerebrospinal fluid is produced by A. dural mater. B. pia mater. C. ventricles. D. ependymal cells (The ependyma is made up of ependymal cells, ependymocytes. These epithelial-like cells line the CSF-filled ventricles in the brain and the central canal of the spinal cord. The cells are ciliated simple cuboidal epithelium-like cells. Their apical surfaces are covered in a layer of cilia, which circulate CSF around the CNS. Their apical surfaces are also covered with microvilli, which absorb CSF. Ependymal cells are a type of glial cell and are also CSF producing cells. Within the ventricles of the brain, a population of modified ependymal cells and capillaries together form a system called the choroid plexus, which produces the CSF. Modified tight junctions between ependymal cells control fluid release across the epithelium. This release allows free exchange between CSF and nervous tissue of brain and spinal cord. This is why sampling of CSF (e.g. through a "spinal tap") gives one a window to the CNS. The basal membrane of these cells are characterized by tentacles like extensions that attach to astrocytes.. 34. The central nervous system includes the A. spinal nerves. B. brain. C. cranial nerves. D. sensory receptors. 35. An interneuron carries impulses A. to muscles and glands. B. to the CNS. C. always within the CNS. 36. Which part of the brain serves to coordinate skeletal muscle movements? A. cerebrum B. diencephalon C. pons D. cerebellum 37. Which of the following contains the nucleus? A. axon B. dendrite C. cell body D. none of these 38. What is/are the main function (s) of the spinal cord? A. reflex center B. relay center between brain and peripheral nerves C. reflex center and relay center between brain and peripheral nerves Revised: 7/22/2008 1 0 39. The neurotransmitter used by the parasympathetic nervous system is A. norepinephrine. B. dopamine. C. serotonin. D. acetylcholine. True / False Questions 40. The afferent division of the peripheral nervous system carries motor fibers. True False 41. The right side of the brain controls the right side of the body. True False 42. The conduction of an action potential obeys the all-or-none law. True False 43. The brain and spinal cord make up the peripheral nervous system. True False 44. The autonomic nervous system is in control of voluntary activities. True False 45. Gaps in the myelin sheath are called nodes of Ranvier. True False Essay Questions 46. When someone is frightened, they seem to have more strength to run or fight than normal. What is the reason for this? 47. List and describe the three types of functional areas in the cerebrum. 48. If a person had an injury to the occipital lobe of the cerebrum, what functional losses would you expect them to have? Chapter 9 Special Sense/The Sensory System 49. Sensory receptors for sensing pain are called: a. proprioceptors b. photoreceptors c. nociceptors d. thermoreceptors 50. Which of the following is a receptor for fine touch? a. Meissner corpuscles b. Ruffini endings c. Krause end bulbs d. Pacinian corpuscles 51. Following are pairs of sensory receptors and stimuli to which the respond. Choose the correct pair(s). a. Golgi tendon organs-excessive muscle contraction b. Visceral nociceptors-oxygen deprivation to an organ c. Merkel disks-pressure d. a and b e. All of the above Revised: 7/22/2008 1 1 52. Which of the following statements about taste is correct? a. Taste buds are located in the back of the throat (pharynx). b. Taste buds respond to five primary taste sensations. c. Taste buds are a type of chemoreceptor d. a and b e. all of the above 53. Select a correct statement about the sense of smell: a. Taste and smell sensations travel through some of the same brain areas. b. Olfactory epithelium is located right at the entrance to the nasal cavity. c. An odor is made by a single type of odor molecule d. All of the above 54. Complete this statement correctly: The gustatory (taste) control center is located in the _____ lobe and the olfactory (smell) area is located in the ____ lobe of the brain. a. insula, temporal b. temporal, parietal c. frontal, temporal d. occipital, frontal 55. Which of the following structures is a part of the choroid layer of the eye? a. iris b. vitreous body c. retina d. cornea 56. The posterior compartment of the eye is filled with: a. aqueous humor b. tears c. blood d. vitreous humor 57. Which statement is true? a. Rod cells can be found in the fovea. b. Light stimulus to rod cells stops the release of neurotransmitter from the rods. c. Cone cells provide peripheral vision. d. Cone cells are spread evenly throughout the retina. 58. The sensory organs for position and movement are called ________. 59. Taste buds and olfactory cells are termed _________ because they are sensitive to chemicals in the air and food. 60. The sensory receptors for sight, the ________ and __________ are located in the ________, the inner layer of the eye. 61. The cones give us ________ vision and work best in ________ light. 62. The lens _______ for viewing close objects 63. People who are nearsighted cannot see objects that are _________. A ________ lens will restore this ability. 64. The ossicles are the ________, __________, and ___________. 65. The semicircular canals are involved in the sense of _________. 66. The spiral organ is located in the _________ canal of the ________. 67. Vision, hearing, taste and smell do not occur unless nerve signals reach the proper portion of the _________. Revised: 7/22/2008 1 2 68. Name the 5 different types of general sensory receptors, define them, and explain their functions in your own words. 69. How are somatic and visceral nociceptors alike? How are they different? 70. Describe the relationship between taste and smell. Revised: 7/22/2008 1 3 Revised: 7/22/2008 1