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Spinal Cord and Reflexes Muse: Lecture #14 7/7/10 Spinal cord, nerves and reflexes Figure 13–1 An Overview of Chapters 13 and 14. Central nervous system (CNS) Peripheral nervous system (PNS) Sensory (afferent) division Motor (efferent) division Somatic nervous system Sympathetic division accelerator Autonomic nervous system (ANS) Parasympathetic division brake Figure 13.1 Spinal Cord  Gross Anatomy of the Spinal Cord  About 18 inches (45 cm) long  1/2 inch (14 mm) wide  Ends between vertebrae L1 and L2  Bilateral symmetry  Grooves divide the spinal cord into left and right  Posterior median sulcus: on posterior side  Anterior median fissure: deeper groove on anterior side Spinal Cord  Gross Anatomy of the Spinal Cord  The Distal End  Conus medullaris: – thin, conical spinal cord below lumbar enlargement  Filum terminale: – thin thread of fibrous tissue at end of conus medullaris – attaches to coccygeal ligament  Cauda equina: – nerve roots extending below conus medullaris Spinal Cord Figure 13–2 Gross Anatomy of the Adult Spinal Cord. Spinal Cord Figure 13–2 Gross Anatomy of the Adult Spinal Cord. Made by Honda? Spinal Cord  31 Spinal Cord Segments  Based on vertebrae where spinal nerves originate  Positions of spinal segment and vertebrae change with age  Cervical nerves: – are named for inferior vertebra  All other nerves: – are named for superior vertebra Spinal Cord  Roots  Two branches of spinal nerves  Ventral root: – contains axons of motor neurons  Dorsal root: – contains axons of sensory neurons  Dorsal root ganglia  contain cell bodies of sensory neurons Spinal Cord  The Spinal Nerve  Each side of spine  Dorsal and ventral roots join  To form a spinal nerve  Mixed Nerves  Carry both afferent (sensory) and efferent (motor) fibers Spinal Cord Figure 13–3 The Spinal Cord and Spinal Meninges Spinal Cord Figure 13–3 The Spinal Cord and Spinal Meninges Spinal Cord  The Spinal Meninges  Specialized membranes isolate spinal cord from surroundings  Functions of the spinal meninges include  Protect spinal cord  Carry blood supply  Continuous with cranial meninges  Meningitis:  Viral or bacterial infection of meninges Spinal Cord  The Three Meningeal Layers  Dura mater  Outer layer of spinal cord  Arachnoid mater  Middle meningeal layer  Pia mater  Inner meningeal layer Spinal Cord  The Dura Mater  Tough and fibrous  Cranially  Fuses with periosteum of occipital bone  Is continuous with cranial dura mater  Caudally  Tapers to dense cord of collagen fibers  Joins filum terminale in coccygeal ligament  The Epidural Space  Between spinal dura mater and walls of vertebral canal  Contains loose connective and adipose tissue  Anesthetic injection site Spinal Cord  The Arachnoid Mater  Middle meningeal layer  Arachnoid membrane  Simple squamous epithelia  Covers arachnoid mater Spinal Cord  The Interlayer Spaces of Arachnoid Mater  Subdural space  Between arachnoid mater and dura mater  Subarachnoid space  Between arachnoid mater and pia mater  Contains collagen/elastin fiber network (arachnoid trabeculae)  Filled with cerebrospinal fluid (CSF)  Cerebrospinal Fluid (CSF)  Carries dissolved gases, nutrients, and wastes  Spinal tap: withdraws CSF Spinal Cord  The Pia Mater  Is the innermost meningeal layer  Is a mesh of collagen and elastic fibers  Is bound to underlying neural tissue Spinal Cord Figure 13–4 The Spinal Cord and Associated Structures Gray Matter and White Matter  Sectional Anatomy of the Spinal Cord  White matter  Is superficial  Contains myelinated and unmyelinated axons  Gray matter  Surrounds central canal of spinal cord  Contains neuron cell bodies, neuroglia, unmyelinated axons  Has projections (gray horns) Gray Matter and White Matter  Organization of Gray Matter  The gray horns  Posterior gray horns: contain somatic and visceral sensory nuclei  Anterior gray horns: contain somatic motor nuclei  Lateral gray horns: are in thoracic and lumbar segments; contain visceral motor nuclei  Gray commissures  Axons that cross from one side of cord to the other before reaching gray matter Gray Matter and White Matter  Organization of Gray Matter  The cell bodies of neurons form functional groups called nuclei  Sensory nuclei: – dorsal (posterior) – connect to peripheral receptors  Motor nuclei: – ventral (anterior) – connect to peripheral effectors Gray Matter and White Matter  Control and Location  Sensory or motor nucleus location within the gray matter determines which body part it controls Gray Matter and White Matter  Organization of White Matter  Posterior white columns: lie between posterior gray horns and posterior median sulcus  Anterior white columns: lie between anterior gray horns and anterior median fissure  Anterior white commissure: area where axons cross from one side of spinal cord to the other  Lateral white columns: located on each side of spinal cord between anterior and posterior columns Gray Matter and White Matter  Organization of White Matter  Tracts or fasciculi  In white columns  Bundles of axons  Relay same information in same direction  Ascending tracts: – carry information to brain  Descending tracts: – carry motor commands to spinal cord Gray Matter and White Matter Figure 13–5a The Sectional Organization of the Spinal Cord. Gray Matter and White Matter Figure 13–5b The Sectional Organization of the Spinal Cord. Spinal Cord Summary  Spinal cord has a narrow central canal  Surrounded by gray matter  Containing sensory and motor nuclei  Sensory nuclei are dorsal SounD  Motor nuclei are ventral MoVe Spinal Cord Summary  Gray matter  Is covered by a thick layer of white matter  White matter  Consists of ascending and descending axons  Organized in columns  Containing axon bundles with specific functions  Spinal cord is so highly organized  It is possible to predict results of injuries to specific areas Spinal Nerves and Plexuses  Anatomy of Spinal Nerves  Every spinal cord segment  Is connected to a pair of spinal nerves  Every spinal nerve  Is surrounded by three connective tissue layers  That support structures and contain blood vessels Spinal Nerves and Plexuses  Three Connective Tissue Layers of Spinal Nerves  Epineurium  Outer layer  Dense network of collagen fibers  Perineurium  Middle layer  Divides nerve into fascicles (axon bundles)  Endoneurium  Inner layer  Surrounds individual axons Spinal Nerves and Plexuses Figure 13–6a A Peripheral Nerve. Spinal Nerves and Plexuses  Peripheral Nerves  Interconnecting branches of spinal nerves  Surrounded by connective tissue sheaths Spinal Nerves and Plexuses Spinal Nerves and Plexuses  Peripheral Distribution of Spinal Nerves  Sensory nerves  In addition to motor impulses: – dorsal, ventral, and white rami also carry sensory information  Dermatomes  Bilateral region of skin  Monitored by specific pair of spinal nerves Spinal Nerves and Plexuses Figure 13–7b Peripheral Distribution of Spinal Nerves. Spinal Nerves and Plexuses Figure 13–8 Dermatomes. Spinal Nerves and Plexuses  Peripheral Neuropathy  Regional loss of sensory or motor function  Due to trauma or compression  chronic can be due to diabetes Spinal Nerves and Plexuses  Nerve Plexuses  Complex, interwoven networks of nerve fibers  Formed from blended fibers of ventral rami of adjacent spinal nerves  Control skeletal muscles of the neck and limbs Spinal Nerves and Plexuses  The Four Major Plexuses of Ventral Rami  Cervical plexus  Brachial plexus  Lumbar plexus  Sacral plexus Spinal Nerves and Plexuses Figure 13–10 Peripheral Nerves and Nerve Plexuses. Spinal Nerves and Plexuses Figure 13–10 Peripheral Nerves and Nerve Plexuses. Spinal Nerves and Plexuses  The Cervical Plexus of the Ventral Rami  Includes ventral rami of spinal nerves C1–C5  Innervates neck, thoracic cavity, diaphragmatic muscles  Major nerve  Phrenic nerve (controls diaphragm) Spinal Nerves and Plexuses Figure 13–11 The Cervical Plexus. Spinal Nerves and Plexuses Spinal Nerves and Plexuses Includes ventral rami of spinal nerves C5–T1  The Brachial Plexus of the Ventral Rami  Major nerves of brachial plexus  Musculocutaneous nerve (lateral cord)  Median nerve (lateral and medial cords)  Ulnar nerve (medial cord)  Axillary nerve (posterior cord)  Radial nerve (posterior cord) Spinal Nerves and Plexuses Figure 13–12a The Brachial Plexus. Spinal Nerves and Plexuses Figure 13–12b The Brachial Plexus. Spinal Nerves and Plexuses Figure 13–12c The Brachial Plexus. Spinal Nerves and Plexuses Spinal Nerves and Plexuses  The Lumbar Plexus of the Ventral Rami  Includes ventral rami of spinal nerves T12–L4  Major nerves  Genitofemoral nerve  Lateral femoral cutaneous nerve  Femoral nerve Spinal Nerves and Plexuses  The Sacral Plexus of the Ventral Rami  Includes ventral rami of spinal nerves L4–S4  Major nerves  Pudendal nerve  Sciatic nerve  Branches of sciatic nerve  Fibular nerve  Tibial nerve 3D Rotation of Lumbar and Sacral Plexuses Spinal Nerves and Plexuses Figure 13–13b The Lumbar and Sacral Plexuses. Spinal Nerves and Plexuses Figure 13–13d The Lumbar and Sacral Plexuses. Neuronal Pools  Functional Organization of Neurons  Sensory neurons  About 10 million  Deliver information to CNS  Motor neurons  About 1/2 million  Deliver commands to peripheral effectors  Interneurons  About 20 billion  Interpret, plan, and coordinate signals in and out Neuronal Pools  Neuronal Pools  Functional groups of interconnected neurons (interneurons)  Each with limited input sources and output destinations  May stimulate or depress parts of brain or spinal cord Neuronal Pools Five Patterns of Neural Circuits in Neuronal Pools  Divergence  Spreads stimulation to many neurons or neuronal pools in CNS  Convergence  Brings input from many sources to single neuron  Serial processing  Moves information in single line Neuronal Pools  Five Patterns of Neural Circuits in Neuronal Pools  Parallel processing  Moves same information along several paths simultaneously  Reverberation  Positive feedback mechanism  Functions until inhibited Neuronal Pools Figure 13–14 Neural Circuits: The Organization of Neuronal Pools. Reflexes  Automatic responses coordinated within spinal cord  Through interconnected sensory neurons, motor neurons, and interneurons  Produce simple and complex reflexes Reflex Arc 2 SENSORY NEURON (axon conducts impulses from receptor to integrating center) 1 SENSORY RECEPTOR (responds to a stimulus by producing a generator or receptor potential) Interneuron 3 INTEGRATING CENTER (one or more regions within the CNS that relay impulses from sensory to motor neurons) 4 MOTOR NEURON (axon conducts impulses from integrating center to effector) 5 EFFECTOR (muscle or gland that responds to motor nerve impulses) Reflexes  Neural Reflexes     Rapid, automatic responses to specific stimuli Basic building blocks of neural function One neural reflex produces one motor response Reflex arc     The wiring of a single reflex Beginning at receptor Ending at peripheral effector Generally opposes original stimulus (negative feedback) Reflexes  Five Steps in a Neural Reflex  Step 1: Arrival of stimulus, activation of receptor  Physical or chemical changes  Step 2: Activation of sensory neuron  Graded depolarization  Step 3: Information processing by postsynaptic cell  Triggered by neurotransmitters  Step 4: Activation of motor neuron  Action potential  Step 5: Response of peripheral effector  Triggered by neurotransmitters Reflexes Figure 13–15 Events in a Neural Reflex. Reflexes  Four Classifications of Reflexes  By early development  By type of motor response  By complexity of neural circuit  By site of information processing Reflexes  Development  How reflex was developed  Innate reflexes: – basic neural reflexes – formed before birth  Acquired reflexes: – rapid, automatic – learned motor patterns Reflexes  Motor Response  Nature of resulting motor response  Somatic reflexes: – involuntary control of nervous system » superficial reflexes of skin, mucous membranes » stretch or deep tendon reflexes (e.g., patellar, or “kneejerk”, reflex)  Visceral reflexes (autonomic reflexes): – control systems other than muscular system Reflexes  Complexity of Neural Circuit  Monosynaptic reflex  Sensory neuron synapses directly onto motor neuron  Polysynaptic reflex  At least one interneuron between sensory neuron and motor neuron  Site of Information Processing  Spinal reflexes  Occurs in spinal cord  Cranial reflexes  Occurs in brain Reflexes Figure 13–16 The Classification of Reflexes. Spinal Reflexes  Spinal Reflexes  Range in increasing order of complexity  Monosynaptic reflexes  Polysynaptic reflexes  Intersegmental reflex arcs: – many segments interact – produce highly variable motor response Spinal Reflexes  Monosynaptic Reflexes  A stretch reflex  Have least delay between sensory input and motor output:  For example, stretch reflex (such as patellar reflex)  Completed in 20–40 msec  Receptor is muscle spindle Spinal Reflexes Figure 13–17 A Stretch Reflex. Spinal Reflexes  Postural reflexes  Stretch reflexes  Maintain normal upright posture  Stretched muscle responds by contracting  Automatically maintain balance Spinal Reflexes  Polysynaptic Reflexes  More complicated than monosynaptic reflexes  Interneurons control more than one muscle group  Produce either EPSPs or IPSPs Excitory post synaptic potentials Spinal Reflexes  The Tendon Reflex Polysynaptic  Prevents skeletal muscles from  Developing too much tension  Tearing or breaking tendons  Sensory receptors unlike muscle spindles or proprioceptors To brain Inhibitory interneuron 5 EFFECTOR (muscle attached to same tendon) relaxes and relieves excess tension 4 MOTOR NEURON inhibited + ++ 2 SENSORY NEURON excited – Increased tension stimulates 1 SENSORY RECEPTOR (tendon) + Spinal nerve 3 Within INTEGRATING + Antagonistic muscles contract CENTER (spinal cord), sensory neuron activates inhibitory interneuron Motor neuron to antagonistic muscles is excited Excitatory interneuron Spinal Reflexes  Withdrawal Reflexes  Move body part away from stimulus (pain or pressure)  For example, flexor reflex: – pulls hand away from hot stove  Strength and extent of response  Depends on intensity and location of stimulus Spinal Reflexes Figure 13–19 A Flexor Reflex. Spinal Reflexes  Reciprocal Inhibition  For flexor reflex to work  The stretch reflex of antagonistic (extensor) muscle must be inhibited (reciprocal inhibition) by interneurons in spinal cord Spinal Reflexes  Reflex Arcs  Ipsilateral reflex arcs  Occur on same side of body as stimulus  Stretch, tendon, and withdrawal reflexes  Crossed extensor reflexes  Involve a contralateral reflex arc  Occur on side opposite stimulus Spinal Reflexes  Crossed Extensor Reflexes  Occur simultaneously, coordinated with flexor reflex  For example, flexor reflex causes leg to pull up  Crossed extensor reflex straightens other leg  To receive body weight  Maintained by reverberating circuits Spinal Reflexes Figure 13–20 The Crossed Extensor Reflex. Spinal Reflexes  Five General Characteristics of Polysynaptic Reflexes  Involve pools of neurons  Are intersegmental in distribution  Involve reciprocal inhibition  Have reverberating circuits  Which prolong reflexive motor response  Several reflexes cooperate  To produce coordinated, controlled response The Brain Can Alter Spinal Reflexes  Integration and Control of Spinal Reflexes  Reflex behaviors are automatic  But processing centers in brain can facilitate or inhibit reflex motor patterns based in spinal cord The Brain Can Alter Spinal Reflexes  Voluntary Movements and Reflex Motor Patterns  Higher centers of brain incorporate lower, reflexive motor patterns  Automatic reflexes  Can be activated by brain as needed  Use few nerve impulses to control complex motor functions  Walking, running, jumping The Brain Can Alter Spinal Reflexes  Reinforcement of Spinal Reflexes  Higher centers reinforce spinal reflexes  By stimulating excitatory neurons in brain stem or spinal cord  Creating EPSPs at reflex motor neurons  Facilitating postsynaptic neurons The Brain Can Alter Spinal Reflexes  Inhibition of Spinal Reflexes  Higher centers inhibit spinal reflexes by  Stimulating inhibitory neurons  Creating IPSPs at reflex motor neurons  Suppressing postsynaptic neurons The Brain Can Alter Spinal Reflexes  The Babinski Reflexes  Normal in infants  May indicate CNS damage in adults The Brain Can Alter Spinal Reflexes Figure 13–21 The Babinski Reflexes. An Introduction to the Brain and Cranial Nerves  The Adult Human Brain  Ranges from 750 cc to 2100 cc  Contains almost 97% of the body’s neural tissue  Average weight about 1.4 kg (3 lb) The Brain  Six Regions of the Brain  Cerebrum  Cerebellum  Diencephalon  Mesencephalon  Pons  Medulla oblongata The Brain Figure 14–1 An Introduction to Brain Structures and Functions. The Brain Figure 14–2 Ventricles of the Brain. Brain Protection and Support  Physical protection  Bones of the cranium  Cranial meninges  Cerebrospinal fluid  Biochemical isolation  Blood–brain barrier Brain Protection and Support  Cerebrospinal Fluid (CSF)  Surrounds all exposed surfaces of CNS  Interchanges with interstitial fluid of brain  Functions of CSF  Cushions delicate neural structures  Supports brain  Transports nutrients, chemical messengers, and waste products Brain Protection and Support Figure 14–4 The Formation and Circulation of Cerebrospinal Fluid. Brain Protection and Support  Blood Supply to the Brain  Supplies nutrients and oxygen to brain  Delivered by internal carotid arteries and vertebral arteries  Removed from dural sinuses by internal jugular veins Brain Protection and Support Figure 21–23 Arteries of the Brain. Brain Protection and Support  Blood–Brain Barrier  Isolates CNS neural tissue from general circulation  Formed by network of tight junctions  Between endothelial cells of CNS capillaries  Lipid-soluble compounds (O2, CO2), steroids, and prostaglandins diffuse into interstitial fluid of brain and spinal cord  Astrocytes control blood–brain barrier by releasing chemicals that control permeability of endothelium Brain Protection and Support  Blood–CSF Barrier  Formed by special ependymal cells  Surround capillaries of choroid plexus  Limits movement of compounds transferred  Allows chemical composition of blood and CSF to differ Brain Protection and Support  Four Breaks in the BBB  Portions of hypothalamus  Secrete hypothalamic hormones  Posterior lobe of pituitary gland  Secretes hormones ADH and oxytocin  Pineal glands  Pineal secretions  Choroid plexus  Where special ependymal cells maintain blood– CSF barrier The Medulla Oblongata  The Medulla Oblongata  Allows brain and spinal cord to communicate  Coordinates complex autonomic reflexes  Controls visceral functions  Nuclei in the Medulla  Autonomic nuclei: control visceral activities  Sensory and motor nuclei: of cranial nerves  Relay stations: along sensory and motor pathways The Medulla Oblongata Figure 14–5a The Diencephalon and Brain Stem. The Medulla Oblongata Figure 14–5c The Diencephalon and Brain Stem. The Cerebellum  Functions of the Cerebellum  Adjusts postural muscles  Fine-tunes conscious and subconscious movements The Cerebellum  Structures of the Cerebellum  Purkinje cells  Large, branched cells  Found in cerebellar cortex  Receive input from up to 200,000 synapses  Arbor vitae  Highly branched, internal white matter of cerebellum  Cerebellar nuclei: embedded in arbor vitae: – relay information to Purkinje cells The Cerebellum  Structures of the Cerebellum  The peduncles  Tracts link cerebellum with brain stem, cerebrum, and spinal cord: – superior cerebellar peduncles – middle cerebellar peduncles – inferior cerebellar peduncles The Cerebellum  Disorders of the Cerebellum  Ataxia  Damage from trauma or stroke  Intoxication (temporary impairment)  Disturbs muscle coordination The Cerebellum Figure 14–7a The Cerebellum. The Cerebellum Figure 14–7b The Cerebellum. The Diencephalon  Integrates sensory information and motor commands  Thalamus, epithalamus, and hypothalamus  The pineal gland  Found in posterior epithalamus  Secretes hormone melatonin The Diencephalon  The Thalamus  Filters ascending sensory information for primary sensory cortex  Relays information between basal nuclei and cerebral cortex  The third ventricle  Separates left thalamus and right thalamus  Interthalamic adhesion (or intermediate mass): – projection of gray matter – extends into ventricle from each side The Diencephalon  The Thalamus  Thalamic nuclei  Are rounded masses that form thalamus  Relay sensory information to basal nuclei and cerebral cortex The Diencephalon  The Hypothalamus  Mamillary bodies  Process olfactory and other sensory information  Control reflex eating movements  Infundibulum  A narrow stalk  Connects hypothalamus to pituitary gland  Tuberal area  Located between the infundibulum and mamillary bodies  Helps control pituitary gland function The Diencephalon Figure 14–10a The Hypothalamus in Sagittal Section. The Diencephalon  Eight Functions of the Hypothalamus  Provides subconscious control of skeletal muscle  Controls autonomic function  Coordinates activities of nervous and endocrine systems  Secretes hormones  Antidiuretic hormone (ADH) by supraoptic nucleus  Oxytocin (OT; OXT) by paraventricular nucleus The Diencephalon  Eight Functions of the Hypothalamus  Produces emotions and behavioral drives  The feeding center (hunger)  The thirst center (thirst)  Coordinates voluntary and autonomic functions  Regulates body temperature  Preoptic area of hypothalamus  Controls circadian rhythms (day–night cycles)  Suprachiasmatic nucleus The Limbic System  The Limbic System  Is a functional grouping that  Establishes emotional states  Links conscious functions of cerebral cortex with autonomic functions of brain stem  Facilitates memory storage and retrieval The Limbic System  Components of the Limbic System  Amygdaloid body  Acts as interface between the limbic system, the cerebrum, and various sensory systems  Limbic lobe of cerebral hemisphere  Cingulate gyrus  Dentate gyrus  Parahippocampal gyrus  Hippocampus The Limbic System  Components of the Limbic System  Fornix  Tract of white matter  Connects hippocampus with hypothalamus  Anterior nucleus of the thalamus  Relays information from mamillary body to cingulate gyrus  Reticular formation  Stimulation or inhibition affects emotions (rage, fear, pain, sexual arousal, pleasure) The Limbic System Figure 14–11a The Limbic System. The Limbic System Figure 14–11b The Limbic System. The Limbic System The Cerebrum  The Cerebrum  Is the largest part of the brain  Controls all conscious thoughts and intellectual functions  Processes somatic sensory and motor information The Cerebrum  Gray matter  In cerebral cortex and basal nuclei  White matter  Deep to basal cortex  Around basal nuclei The Cerebrum Figure 14–12c The Brain in Lateral View. The Cerebrum  Special Sensory Cortexes  Visual cortex  Information from sight receptors  Auditory cortex  Information from sound receptors  Olfactory cortex  Information from odor receptors  Gustatory cortex  Information from taste receptors The Cerebrum Figure 14–15a Motor and Sensory Regions of the Cerebral Cortex. The Cerebrum The Cerebrum  The Left Hemisphere  In most people, left brain (dominant hemisphere) controls  Reading, writing, and math  Decision making  Speech and language  The Right Hemisphere  Right cerebral hemisphere relates to  Senses (touch, smell, sight, taste, feel)  Recognition (faces, voice inflections) The Cerebrum Figure 14–16 Hemispheric Lateralization. The Cerebrum  Monitoring Brain Activity  Brain activity is assessed by an electroencephalogram (EEG)  Electrodes are placed on the skull  Patterns of electrical activity (brain waves) are printed out The Cerebrum  Four Categories of Brain Waves  Alpha waves  Found in healthy, awake adults at rest with eyes closed  Beta waves  Higher frequency  Found in adults concentrating or mentally stressed  Theta waves  Found in children  Found in intensely frustrated adults  May indicate brain disorder in adults  Delta waves  During sleep  Found in awake adults with brain damage The Cerebrum Figure 14–17a-d Brain Waves. The Cerebrum  Synchronization  A pacemaker mechanism  Synchronizes electrical activity between hemispheres  Brain damage can cause desynchronization  Seizure  Is a temporary cerebral disorder  Changes the electroencephalogram  Symptoms depend on regions affected Cranial Nerves  12 pairs connected to brain  Four Classifications of Cranial Nerves  Sensory nerves: carry somatic sensory information, including touch, pressure, vibration, temperature, and pain  Special sensory nerves: carry sensations such as smell, sight, hearing, balance  Motor nerves: axons of somatic motor neurons  Mixed nerves: mixture of motor and sensory fibers Cranial Nerves Figure 14–18 Origins of the Cranial Nerves. Cranial Nerves  Optic Nerves (II)  Primary function  Special sensory (vision)  Origin  Retina of eye  Pathway  Optic canals of sphenoid  Destination  Diencephalon via optic chiasm Cranial Nerves  Optic Nerve Structures  Optic chiasm  Where sensory fibers converge  And cross to opposite side of brain  Optic tracts  Reorganized axons  Leading to lateral geniculate nuclei Cranial Nerves Figure 14–20 The Optic Nerve. Cranial Nerves  The Vagus Nerves (X)  Primary function  Mixed (sensory and motor)  Widely distributed in thorax and abdomen  Origins  Sensory: – – – – part of pharynx auricle and external acoustic meatus diaphragm visceral organs of thoracic and abdominopelvic cavities  Motor: – motor nuclei in medulla oblongata Cranial Nerves  The Vagus Nerves (X)  Pathway  Jugular foramina  Between occipital and temporal bones  Destination  Sensory: – sensory nuclei and autonomic centers of medulla oblongata  Visceral motor: – muscles of the palate and pharynx – muscles of the digestive, respiratory, and cardiovascular systems in thoracic and abdominal cavities Cranial Nerves Figure 14–26 The Vagus Nerve. Cranial Nerves Figure 14–26 The Vagus Nerve. Cranial Nerves  The Accessory Nerves (XI)  Primary function  Motor to muscles of neck and upper back  Origin  Motor nuclei of spinal cord and medulla oblongata  Pathway  Jugular foramina between occipital and temporal bones  Destination  Internal branch: – voluntary muscles of palate, pharynx, and larynx  External branch: – sternocleidomastoid and trapezius muscles Cranial Nerves Cranial Nerves Cranial Reflexes  Cranial Reflexes  Monosynaptic and polysynaptic reflex arcs  Involve sensory and motor fibers of cranial nerves  Clinically useful to check cranial nerve or brain damage Cranial Reflexes
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            