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Candidate Number C8003 THE UNIVERSITY OF SUSSEX BSc First Year Examination 2015 PSYCHOBIOLOGY SAMPLE PAPER Date Time DO NOT TURN OVER UNTIL INSTRUCTED TO BY THE CHIEF INVIGILATOR Candidates must attempt ALL questions Time allowed: 1 hour The answers, one to each question, should be marked on the answer sheet provided (place a cross in the relevant box to indicate your answer: a, b, c or d). There are 50 questions. INSTRUCTIONS 1. Do not write your name on the question paper (or answer sheet). 2. Do not tear off any part of this question paper. 3. At the end of the examination the question paper and/or answer sheet, used or unused, will be collected from you before you leave the examination room; C8003 Psychobiology SAMPLE PAPER 2015 1. Which of the following structures is NOT part of the mammalian central nervous system? (a) Hypothalamus (b) Pons (c) Spinal cord (d) Vagus 2. Strokes are most commonly caused by: (a) Interruptions in the cerebral blood supply (b) Burst cerebral blood vessels (c) A severe epiletic attach (d) Loss of consciousness 3. Which of the following statements about the autonomic nervous system is CORRECT? (a) Parasympapthetic nerves arise in the midbrain, innervate the heart and decrease heartrate when activated (b) Parasympapthetic nerves arise in the hindbrain, innervate the heart and increase heartrate when activated (c) The autonomic nervous system is composed of sympathetic and parasympathetic components (d) Sympathetic nerves arise in the hindbrain, innervate the heart and decrease heartrate when activated 4. Which of the following words best describes the relationship of the cerebellum to the pons in the human brain? (a) Ventral (b) Rostral (c) Dorsal (d) Parasagittal 2 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 5. Lesions of the right parietal lobe are often associated with cognitive deficits. Which of the following might be observed in such case? (a) Aphasia (b) Acalculia (c) Weakness on the left side of the body (d) Neglect of the left side of the body 6. The descending, or repolarising, phase of an action potential is associated with which of the following types of ionic movement? (a) Chloride moves into the axon (b) Sodium moves in to the axon (c) Potassium moves into the axon (d) Potassium moves out of the axon 7. Which of the following statements about action potentials and synapses is CORRECT? (a) Action potentials involve hyperpolarisation of the neuron (b) Intense stimuli increase the size of the action potential (c) Intense stimuli increase neurotransmitter release at the synapse (d) Glutamate is the primary inhibitory neurotransmitter in the mammalian nervous system 8. Which of the following statements about anxiety is CORRECT? (a) Increase heart rate in anxiety results from activation of the sympathetic nervous system (b) Benzodiazepines enhance the effectiveness of glutamate at glutamatergic synapses (c) Activation of the locus coeruleus reduces the processing of threat related stimuli (d) Damage to the amygdala is likely to increase responsiveness to threat related stimuli 3 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 9. Which of the following statements about GABAergic synapses is CORRECT? (a) GABA depolarises the postsynaptic cell as a consequence of chloride movement into that cell (b) GABA-A receptors have a single binding site at which GABA and alcohol interact (c) GABA is taken up into the presynaptic cell after it acts at the receptor (d) GABA-A receptors require second messenger systems to have their postsynaptic effect 10. Which of the following statements about benzodiazepines, such as Valium, is CORRECT? (a) Benzodiazepines may reduce anxiety by acting on areas of the hippocampus involved in processing threat-related stimuli (b) Benzodiazepines may inhibit the flow of negatively charged chloride ions into nerve cells (c) Benzodiazepines may reduce anxiety by acting on receptors for the neurotransmitter GABA (d) Benzodiazepines may reduce anxiety by acting on areas of the visual cortex involved in processing threat-related stimuli 11. Which of the following is NOT a peptide hormone? (a) Adrenocorticotrophic hormone (ACTH) (b) Corticotrophin releasing factor (CRF) (c) Cortisol (d) Insulin 4 /Turn over C8003 12. Psychobiology SAMPLE PAPER 2015 Which of the following statements about schizophrenia is CORRECT? (a) The size of the lateral ventricles is frequently reduced in schizophrenia (b) Drugs that mimic dopamine are useful in the treatment of schizophrenia (c) A gene located on the human chromosome 7 is strongly and reliably linked to the development of schizophrenia (d) None of the above is correct 13. Which of the following statements about schizophrenia is CORRECT? (a) Base rate liability of schizophrenia is about 5% and is raised to 40% is first degree relatives (b) Base rate liability of schizophrenia is about 1% and is about 4% in second degree relatives (c) The concordance rate for schizophrenia in non-identical twins is about 60% (d) The concordance rate for schizophrenia in non-identical twins is 50% 14. Which of the following actions do all antipsychotic drugs share? (a) Agonists at noradrenalin receptors (b) Antagonists at dopamine receptors (c) Agonists at noradrenalin receptors (d) Antagonists at cholinergic receptors 15. Which of the following statements about misused drugs is CORRECT? (a) Cocaine has its primary effect on brain serotonin systems (b) The major active constituents of cannabis mimics the action of transmitters known as endocannabinoids (c) All effects of amphetamine show tolerance with repeated drug use (d) With repeated cocaine use ‘wanting’ is likely to decrease but ‘liking’ will increase 5 /Turn over C8003 16. Psychobiology SAMPLE PAPER 2015 Which of the following brain structures is activated by viewing a funny cartoon? (a) Raphe nucleus (b) Ventral striatum (c) Parietal lobe (d) Hypothalamus 17. Which of the following neurotransmitters systems does ecstacy (MDMA, or 3,4methylenedioxy-N-methamphetamine) interact with? (a) Serotonin (b) Dopamine (c) GABA (d) Glutamate 18. Remembering when you last went out for dinner to a restaurant is an example of? (a) Episodic memory (b) Semantic memory (c) Procedural memory (d) Non-declarative memory 19. Eric Kandel's research with Alypsia californica found that repeated exposure to a weak tactile stimulus leads to a reduced withdrawal reaction, or ______? (a) Operant conditioning (b) Habituation (c) Classical conditioning (d) Sensitization 6 /Turn over C8003 20. Psychobiology SAMPLE PAPER 2015 In an advertisement making use of classical conditioning, sexual imagery is the and the product being sold is the _________ : (a) Unconditioned stimulus (UCS); unconditioned response (UCR) (b) Unconditioned stimulus (UCS); conditioned stimulus (CS) (c) Conditioned stimulus (CS); conditioned response (CR) (d) Conditioned stimulus (CS); unconditioned stimulus (UCS) 21. A schedule of reinforcement in which a rat is reinforced for pressing a lever 20 times to receive a food pellet is called? (a) A fixed interval schedule (b) A fixed ratio schedule (c) A continuous reinforcement schedule (d) A variable interval schedule 22. Patient H. M., the most studied case in neuroscience, had which area of his brain removed to control his severe epilepsy? (a) Medial-parietal lobe (b) Frontal-lobe (c) Medial-temporal lobe (d) Posterior-parietal lobe 23. According to Walter Cannon: (a) Emotions can never be 'experienced' until the body has time to react (b) The parasympathetic nervous system is responsible for the feeling of emotion (c) Animals without a sympathetic nervous system can still experience emotion (d) Animals without an amygdala cannot experience emotion 7 /Turn over C8003 24. Psychobiology SAMPLE PAPER 2015 Which Nobel-prize winning physiologist was first showed how simple forms of learning are mediated by changes in synaptic transmission? (a) Eric Kandel (b) Arvid Carlson (c) Santiago Ramon y Cajal (d) Ivan Pavlov 25. According to the James-Lange theory, it is the ______ that tells the conscious brain it is experiencing emotion. (a) Amygdala (b) Visual sensation of the emotional stimulus (c) The physiological feedback from the body (d) Hypothalamus 26. A mechanism that works to keep body functions within a certain narrow range is known as: (a) A non-regulatory mechanism (b) A drive (c) An innate releasing mechanism (d) A homeostatic mechanism 27. The existence of the limbic lobe was first recognised in 1878 by: (a) Franz Gall (b) Karl Wernicke (c) John Hughlings Jackson (d) Paul Broca 8 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 28. New technologies have made it possible for researchers to record changes in electrical activity in individual neurons of the brain. Using these techniques, experiments have demonstrated that repeated, strong bursts of electrical stimulation to a presynaptic neuron results in a long-lasting synaptic changes such that the post-synaptic neuron shows a greater electrical response (EPSP). This phenomenon is called? (a) A reverberating neural ensemble (b) Neurogenesis (c) Long-term potentiation (d) Conditioning 29. Jennifer is thirsty. If she is experiencing osmotic thirst, we can assume: (a) Her mouth is dry (b) She has a high concentration of NaCl in her intracellular fluid (c) She has experienced an increase in extracellular fluid (d) She has been sweating profusely 30. Which of the following 2 peptide hormones serve as satiety and hunger signals, respectively? (a) Polypeptide Y and Ghrelin (b) Ghrelin and orexin (c) Orexin and Leptin (d) Cholecystokinin and Leptin 31. The type of associative learning first described by Ivan Pavlov is dependent on normal functioning of which brain region? (a) The hippocampus (b) The striatum (c) The amygdala (d) The pons 9 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 32. Thirst cause by changes in intracellular salt loss is called? (a) Osmometric thirst (b) Anticipatory thrist (c) Hypovolemic thirst (d) Volumetric thirst 33. In the Papaz circuit, the ______ projects to the hypothalamus via a long arcing pathway called the fornix. (a) Amygdala (b) Cingulate cortex (c) Hippocampus (d) Frontal cortex 34. Functional brain imaging studies with human cocaine addicts have demonstrated that merely viewing videos associated with using cocaine: (a) Increases self-reports of drug craving and activates the amygdala, orbital frontal cortex and anterior cigulate (b) Increased feelings of withdrawal, and activated areas of the brain involved in stress (c) Increased self-reports of drug craving but had no reliable effect on brain activity (d) Led to abstinent addicts relapsing shortly after finishing the experiment 35. Which of the following statements about the evolution of group living is FALSE? (a) Some animals live in groups because this enhances their competitive ability (b) Some animals live in groups because this is good for the survival of the species (c) Some animals live in groups because individuals can pass on more of their genes this way (d) Some animals live in groups and help close kin to breed because this enhances their own fitness 10 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 36. Indirect benefits to group living refer to: (a) Non-genetic benefits (b) Genetic benefits (c) Anti-predator benefits (d) None of the above 37. In non-human primate social groups, which of the following signals are NOT used to appease opponents after fights? (a) Grunts (b) Threat faces (c) Grooming (d) All of the above are used in appeasement 38. Which of the following is NOT thought to be a product of sexual selection? (a) Roaring in red deer (b) Eye-spots on peacock tails (c) Alarm calling in monkeys (d) Croaking in frogs 39. Which of the following statements about song repertoires in birds are FALSE? If all are true choose d). (a) The repertoire describes the number of songs that a male sings (b) Males that sing larger repertoires of songs are usually fitter (c) Females often prefer males that sing large repertoires of songs (d) All of the above are true 40. Resource Holding Potential would be the correct term for: (a) Fighting ability (b) Hunting ability (c) Predator avoidance (d) None of the above 11 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 41. Which of the following best describes referential signalling? (a) Signalling about predators (b) The use of an arbitrary language (c) Signalling about close relatives (d) Using signals to denote external objects and events 42. Dasser’s work on captive java monkeys demonstrated that these monkeys were capable of recognising: (a) Predators (b) Mother-offspring relationships (c) Other groups (d) None of the above 43. Which of the following would NOT be expected to affect an individual’s dominance rank in non-human primates? If all might affect dominance rank choose d). (a) Mother’s dominance rank (b) Body size (c) Dominance rank of alliance partners (d) All of the above could affect dominance rank 44. Which of the following statements best describes cultural evolution? (a) Evolution of mind (b) Transmission of behaviour between generations through social learning (c) Genetic transmission of behaviour between generations (d) None of the above 12 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 45. Which of the following is NOT typically found in chimpanzees? (a) Co-operative hunting (b) Tool use (c) A monogamous mating system (d) A fission-fusion society 46. The environment in which much of human evolution occurred is often referred to as: (a) The Evolutionary Environment for Adaptation (b) The Adaptation Environment (c) The Environment of Evolutionary Adaptedness (d) The Cenozoic 47. Daly & Wilson’s study of care of genetic versus non-genetic offspring claims to provide evidence of: (a) Reciprocal altruism (b) Kin selection (c) Sexual selection (d) None of the above 48. Which of the following is TRUE? Sexual dimorphism is typically: (a) Greater in monogamous than polygynous mating systems (b) Greater in polygynous than monogamous mating systems (c) Greater where males have higher potential reproductive rates than females (d) b and c are both true [Note: If d is the correct answer, no credit will be given for answering b or c.] 13 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 49. When Darwin talked of the “survival of the fittest”, he was specifically referring to the survival of individuals that were: (a) Better able to pass on their own genes to the next generation (b) Healthier (c) More aggressive (d) Better able to escape from predators 50. Workman and colleagues propose that hemispheric specialization in emotional processing is best summarized as: (a) Right hemisphere processing for pro-social expressions (b) Left hemisphere processing for pro-social expressions (c) Right hemisphere processing for anti-social expressions (d) b AND c above [Note: If d is the correct answer, no credit will be given for answering b or c.] END OF PAPER 14 /Turn over C8003 Psychobiology SAMPLE PAPER 2015 ANSWERS 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 d a c c d d c a c c c d b b b b a a b b b c c a c 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 d d c b a c a c a b b b c d a d b d b c c b d a d 15