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Neurons are masses of nerve cells that transmit information to other nerves, tissues or cells (nerve impulses). Consists of 1. cell body- contains the nucleus and two extensions. 2. dendrites- shorter, more numerous, receive information. (carry to the cell body) 3. Axons- single, long fiber which conducts impulses away from the cell body. Central nervous system (CNS) Consists of the brain and spinal cord Peripheral Nervous System (PNS) Includes 31 pairs of spinal nerves Includes 12 pairs of cranial nerves 1. Sensory Function- gathers information within and around the body, sends nerve impulses to the CNS. 2. Integrative function- information is interpreted, to create sensations, create thoughts, add to memory, make decisions, etc. 3. Motor Function- responds to signals (impulses). Signals go from the CNS to effectors (muscles or glands). Integration center of the body Constant input from sensory organs Constant learning Memory of response or outcome Huge collection of myelinated and unmyelinated neurons Divided into lobes: different sensory and motor functions are controlled by different lobes. Three major parts: Cerebrum: largest, sensory and motor functions, higher mental function (memory, reasoning) Cerebellum- coordinate voluntary muscles Brain stem- regulate visceral functions Sulci and gyri are along the surface Sulci are shallow grooves Gyri are ridges or bumps Fissures are deep grooves Major sensory lobe Hard drive/memory Speech understanding-Broca’s area Recognition of people, places, items, events, etc. Memory of outcomes taste Occipital Receives input from the eyes and sends it to the parietal lobe for interpretation Temporal lobe: lobe: receives input from the ears and sends it to the parietal lobe for interpretation memory processing –short term Cerebellum: fine motor coordination balance and posture *increases its control with practice 1. auditory and visual reflexes eye movement fluidity of movement 2. pons: integration center for cerebellum and cerebral communication respiratory center 3. midbrain: medulla oblongata: involuntary muscle control autonomic reflexes respiratory/cardiovascular center vomiting, coughing, hiccupping, sneezing, swallowing The neuron: Large, complex cells Longevity: long life Lack centrioles- cannot perform mitosis Classified by structure and function Cell body: contains the nucleus and all other cellular organelles along with the bulk of cytoplasm Dendrites: receptive or input regions that provide enormous surface area for receiving signals from receptor organs/glands Axon: in each neuron, there is only one! It can be very long or so short it seems nonexistent. Conduction component that generates and propagates nerve impulses away from the cell body. Myelin: fatty covering that insulates the axon. Gaps between myelin are called nodes of Ranvier. 2-4 mph without myelin 250 mph with myelin Axon terminal: end of the axon where neurotransmitters are stored and released. Sensory: receive impulses and transmit to the brain -afferent neurons Motor: receive impulses from the brain and send them to effector organs -efferent neurons Interneuron: communicate between motor and sensory along the spinal cord -association neurons Multipolar: 3 or more attachments to the cell body *** most common structure Bipolar: 2 attachments to the cell body *** rare- special senses Unipolar: 1 attachment to the cell body *** rare- PNS sensations Supportive tissue of the nervous system (more numerous than neurons) 5 types: Microglial cells Oligodendrites Astrocytes Ependymal cells Schwann cells Ependymal: In CNS Epithelial cells Produce and form a barrier between neurons and CSF Oligodendrocyte: in CNS Branching cells Wrap their branches around the neuron’s axon insulating it with myelin Astrocyte –in CNS Small, branching cell Most abundant neuroglia Braces neurons to capillariesexchanges between neurons and capillaries Microglia- in CNS Thorny cells Monitors neuron health Satellite Cell: in Schwann PNS PNS Looks like moons or satellites Job is still unknown but thought to act as astrocytes Cell: in Has branching extensions like oligodendrocytes Wraps its branches around PNS neuron axons to insulate them with myelin Nerve impulse: propagation of an impulse from dendrite to axon terminal Resting membrane potential: high concentration of sodium ions outside the membrane and a high concentration of potassium inside the cell. Na/K channel vs Na/K pump: channels are open and allow ions to flow freely while pumps turn off and on to reset the membrane potential Depolarization: neuron membrane is more permeable to sodium ions. * Na+ flows into the neuron Repolarization: neuron membrane is more permeable to potassium ions. *K+ flows out of the neuron Hyperpolarization: too much potassium leaves making the neuron too negative ~ -90mV After hyperpolarization,sodium/potassium pumps reset the resting membrane potential.