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Sensory Pathways (Ascending Tracts) Dr Ayman G. Abu-Tabanja First order neuron: Located in posterior root ganglion Second order neuron: Give an axon that cross Medline and ascend to higher level of the CNS Third order neuron: Located in the thalamus, send axons to sensory region of cerebral cortex Some afferent pathways send branches to: 1. Reticular formation: activate cerebral cortex and maintain wakefulness 2. Motor neurons: reflex muscular activity Lateral Spinothalamic Tract This tract Conducts Pain and Temperature • Second order neurons give axons that cross medline through anterior gray and white commissures within one spinal segment • Fibers ascend as Lateral spinothalamic tract • In brainstem, the tract ascends through spinal lemniscus • Spinal lemniscus: bundle of fibers that contain lateral spinothalamic tract, anterior spinothalamic tract, Spinotectal tract Anterior Spinothalamic Tract This tract conducts light (crude) touch and pressure pathways Second order neurons give axons that cross medline through anterior gray and white commissures within several segments Fibers ascend as anterior spinothalamic tract In brainstem, the tract ascends through spinal lemniscus Posterior white column Tracts Conducts: Descriminative touch Vibratory sense Conscious muscle joint sense First order neurons: send axons that pass directly to posterior white column Most of these axons ascend upward as bundles known as: 1. Fasciculus gracilis: present in all spinal cord segments Contain axons from sacral, lumbar and lower thoracic 2. Fasciculus cuneatus: Present in upper thoracic and all cervical segments • Axons will synapse with 2nd order neurons located in: Nucleus gracilis Nucleus cuneatus Axons of 2nd order neurons cross midline Crossing axons are called : Internal arcuate fibers Axons ascend in a bundle known as Medial lemniscus to synapse with 3rd order neurons in thalamus Posterior Spinocerebellar Tract Anterior Spinocerebellar Tract Cuneocerebellar Tract These tracts conduct: Muscle joint sense to the cerebellum Posterior spinocerebellar tract Axons of second order neurons ascend within the lateral white column on the same side Axons enter through inferior cerebellar Peduncle to reach cerebellar cortex Anterior spinocerebellar tract: Most Axons of second order neurons Cross medline and ascend within the lateral white column of opposite side Axons enter through Superior Cerebellar Peduncle to reach cerebellar cortex Cuneocerebellar Tract: Originate from nucleus cuneatus Enter cerebellum through Inferior cerebellar peduncle on the same side The fibers of this tract is called: Posterior external arcuate fibers Loss of all motor and sensory functions Bilateral LMN Lesion Bilateral UMN lesion Bladder and bowel functions are not controlled Bilateral LMN Lesion Bilateral UMN lesion Loss of pain, temperature and light touch sensations Bilateral LMN Lesion Bilateral UMN lesion ( (Sacral sparing Loss of sensations !!!!!? Ipsilateral LMN Lesion Ipsilateral UMN lesion Contralateral Loss of pain & temperature sensations