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Eukaryotic Genome & Gene Expression Genome Structure and Postranscriptional Events Pre-mRNA Splicing Polyadenylation Capping pppGp mRNA AAAAAAA250 Eukaryotic Transcription & Translation are Compartmentalized Categories of Genes and Non-Coding Sequences • Class I genes rDNA encodes rRNA Moderately repetitive sequences Transcribed by RNA polymerase I • Class II genes mRNA (protein encoding) and snRNA Unique sequences Transcribed by RNA polymerase II • Class III genes tRNA, 5S rRNA, U6 snRNA Moderately repetitive sequences Transcribed by RNA polymerase III • Non-coding regions Repetitive elements Transposable elements (some transcribed) Pseudogenes Moderately Repetitive Sequences Code for rRNA Structure and Transcription of a Eukaryotic Gene The Globin Gene Family Differential Expression in the Globin Gene Family Processing the Ends of Eukaryotic Pre-mRNA The Spliceosome, an RNA Splicing Machine Alternative Splicing Results in Different mRNAs and Proteins Points of Regulation of Gene Expression Eukaryotic Transcription Initiation Eukaryotic Transcription Initiation Coordinating Gene Expression Protein-DNA Interactions Local Remodeling of Chromatin for Transcription A Barr Body in the Nucleus of a Female Cell A Model for X Chromosome Inactivation The Proteasome Breaks Down Proteins Comparison of Prokaryotic and Eukaryotic Genes and Genomes Comparison of E.coli and Yeast Genomes C. elegans Genes Essential to Multicellularity Arabidopsis Genes Unique to Plants Comparison of Rice and Arabidopsis Genomes