Determining the Transcription Factor Genes Populating a Fruit Fly
... the instructions to make these traits are encoded in its DNA sequence. Since many organisms share a considerable amount of the same genetic sequences, the question arises as to how diverse traits are formed. One explanation is that diversity results from variation in how genes are expressed, which h ...
... the instructions to make these traits are encoded in its DNA sequence. Since many organisms share a considerable amount of the same genetic sequences, the question arises as to how diverse traits are formed. One explanation is that diversity results from variation in how genes are expressed, which h ...
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... The mutant phenotype of gnom was first described by Jürgens et al. (Jürgens et al., 1991). gnom mutant embryos fail to properly form a root and shoot apical meristem, and bilateral symmetry is not established, resulting in a ball-shaped embryo. To better understand the origin of the patterning defec ...
... The mutant phenotype of gnom was first described by Jürgens et al. (Jürgens et al., 1991). gnom mutant embryos fail to properly form a root and shoot apical meristem, and bilateral symmetry is not established, resulting in a ball-shaped embryo. To better understand the origin of the patterning defec ...
Nectary formation is ABC independent - Development
... UNUSUAL FLORAL ORGANS. Even though nectary glands arise from cells previously expressing the B class ...
... UNUSUAL FLORAL ORGANS. Even though nectary glands arise from cells previously expressing the B class ...
TRANSLOCATIONS INVOLVING T H E THIRD AND THE FOURTH
... Cytological changes produced by the translocations.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Genetical consequences of the breakage of the third chromosome in the translocations.. .. Non-disjunction of the fourth chromosome in the translocations.. ..................... Behavi ...
... Cytological changes produced by the translocations.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Genetical consequences of the breakage of the third chromosome in the translocations.. .. Non-disjunction of the fourth chromosome in the translocations.. ..................... Behavi ...
Par-1
... machinery Many components of RNAi machinery have been identified through genetic screening for RNAi defective mutants and through biochemical studies using cell extracts (e.g. Drosophila embryo extract). ...
... machinery Many components of RNAi machinery have been identified through genetic screening for RNAi defective mutants and through biochemical studies using cell extracts (e.g. Drosophila embryo extract). ...
The one-eyed pinhead gene functions in mesoderm and endoderm
... leading to eye fusion and reduction of floor plate (Hatta et al., 1991, 1994). Additionally, a reduced number of hatching gland cells, and lower levels of gsc expression indicate that prechordal plate formation is also weakly affected in cyc mutants (Thisse et al., 1994). Although less well understo ...
... leading to eye fusion and reduction of floor plate (Hatta et al., 1991, 1994). Additionally, a reduced number of hatching gland cells, and lower levels of gsc expression indicate that prechordal plate formation is also weakly affected in cyc mutants (Thisse et al., 1994). Although less well understo ...
Creating order from chaos: epigenome dynamics in
... AT-rich and sometimes prefer to insert into AT-rich regions (Le et al., 2000; Naito et al., ...
... AT-rich and sometimes prefer to insert into AT-rich regions (Le et al., 2000; Naito et al., ...
Endonucleolytic processing of CCAless tRNA precursors by RNase
... To get an idea of what proportion of B.subtilis tRNAs might be affected by the decrease in yqjK expression, speci®c oligonucleotide probes were designed for 11 more tRNAs. As can be seen from the northern blot in Figure 3, precursor species accumulate for ®ve of these tRNAs in the RNA samples isolat ...
... To get an idea of what proportion of B.subtilis tRNAs might be affected by the decrease in yqjK expression, speci®c oligonucleotide probes were designed for 11 more tRNAs. As can be seen from the northern blot in Figure 3, precursor species accumulate for ®ve of these tRNAs in the RNA samples isolat ...
Peer Review Report
... ESR1 functions downstream of cytokinin signalling. We added the following sentences in the Results section to describe these data: “We have previously reported that WIND1 promotes callus formation via the Btype ARABIDOPSIS RESPONSE REGULATOR (ARR)-mediated cytokinin signalling pathway (Iwase et al., ...
... ESR1 functions downstream of cytokinin signalling. We added the following sentences in the Results section to describe these data: “We have previously reported that WIND1 promotes callus formation via the Btype ARABIDOPSIS RESPONSE REGULATOR (ARR)-mediated cytokinin signalling pathway (Iwase et al., ...
Visceral endoderm-restricted translation of Otx1
... their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice lacking Otx1 or Otx2, or (ii) Otx1 and Otx2 gene products might display unique functional properties, specified by their limited aminoacid divergence, that are required in restricted ...
... their temporal and spatial transcriptional control might account for the highly divergent phenotypes observed in mice lacking Otx1 or Otx2, or (ii) Otx1 and Otx2 gene products might display unique functional properties, specified by their limited aminoacid divergence, that are required in restricted ...
Huntingtin function during zebrafish (Danio rerio) development
... functions of these proteins have therefore become a focus of investigation as potential pathogenic pathways. Here, synthetic antisense morpholinos have been used to inhibit the translation of huntingtin protein during early zebrafish development. The results obtained show the effects of huntingtin l ...
... functions of these proteins have therefore become a focus of investigation as potential pathogenic pathways. Here, synthetic antisense morpholinos have been used to inhibit the translation of huntingtin protein during early zebrafish development. The results obtained show the effects of huntingtin l ...
A survey on computational methods for enhancer and
... and negative examples for modeling the general features of enhancers and enhancer targets. As a result, different studies have used a variety of ways to define “gold-standard” enhancers and enhancer targets for training their methods. A lot of these “gold-standard” examples are either not experiment ...
... and negative examples for modeling the general features of enhancers and enhancer targets. As a result, different studies have used a variety of ways to define “gold-standard” enhancers and enhancer targets for training their methods. A lot of these “gold-standard” examples are either not experiment ...
Investigating the functional significance of evolutionarily conserved
... and hypomorphic-antimorph. Null alleles were nonsense mutations resulting in truncation and loss of highly conserved protein domains. Hypomorphic alleles were missense and small deletion mutations in highly conserved protein domains, including the DYTQL motif, YPWM motif and C-terminal domain (CTD). ...
... and hypomorphic-antimorph. Null alleles were nonsense mutations resulting in truncation and loss of highly conserved protein domains. Hypomorphic alleles were missense and small deletion mutations in highly conserved protein domains, including the DYTQL motif, YPWM motif and C-terminal domain (CTD). ...
The Homothorax homeoprotein activates the nuclear localization of
... exd has other roles in addition to its homeotic cofactor function. exd mutant clones caused ectopic eye formation in the ventral head, ventral to dorsal transformation in the imaginal abdomen, affected bristle patterning in the thorax and wing, and affected the proximal leg development (Gonzalez-Cre ...
... exd has other roles in addition to its homeotic cofactor function. exd mutant clones caused ectopic eye formation in the ventral head, ventral to dorsal transformation in the imaginal abdomen, affected bristle patterning in the thorax and wing, and affected the proximal leg development (Gonzalez-Cre ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... (AF15q14) • t(11;15)(q23;q14) → MLL - MPFYVE • t(11;15)(q23;q15) → MLL - AF15 • t(11;16)(q23;p13)/MDS, ANLL, t-ANLL, ALL → MLL - CREBBP (CBP) • t(11;17)(q23;p13)/t-ANLL → MLL - GAS7 • t(11;17)(q23;q21)/ANLL → MLL - ACACA • t(11;17)(q23;q21)/ANLL → MLL - LASP1 • t(11;17)(q23;q21)/ANLL → MLL - MLLT6 ( ...
... (AF15q14) • t(11;15)(q23;q14) → MLL - MPFYVE • t(11;15)(q23;q15) → MLL - AF15 • t(11;16)(q23;p13)/MDS, ANLL, t-ANLL, ALL → MLL - CREBBP (CBP) • t(11;17)(q23;p13)/t-ANLL → MLL - GAS7 • t(11;17)(q23;q21)/ANLL → MLL - ACACA • t(11;17)(q23;q21)/ANLL → MLL - LASP1 • t(11;17)(q23;q21)/ANLL → MLL - MLLT6 ( ...
Attachment 2.2 Sequencing results
... electrophoresis and qPCR to detect the presence of this new transcript (and original transcript) in these tissues. The original transcript was also sequenced. All sequencing results were blasted to the dog genome and the annotated original transcript of the AHR gene. Last, western blotting was perfo ...
... electrophoresis and qPCR to detect the presence of this new transcript (and original transcript) in these tissues. The original transcript was also sequenced. All sequencing results were blasted to the dog genome and the annotated original transcript of the AHR gene. Last, western blotting was perfo ...
Effete, a Drosophila chromatin-associated ubiquitin
... respectively (Fanti et al. 1998; Cenci et al. 2003); without children (woc) that specifies a putative transcription factor (Raffa et al. 2005); modigliani (moi) that encodes a nonconserved HOAP-binding protein (Raffa et al. 2009); and verrocchio (ver) that specifies an OB-fold containing protein str ...
... respectively (Fanti et al. 1998; Cenci et al. 2003); without children (woc) that specifies a putative transcription factor (Raffa et al. 2005); modigliani (moi) that encodes a nonconserved HOAP-binding protein (Raffa et al. 2009); and verrocchio (ver) that specifies an OB-fold containing protein str ...
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... supplementary material). PCR and SNP markers were generated at each position on linkage group 17 and the markers that showed polymorphisms between C108 and a46 were used for the genetic analysis of 839 F2 individuals with the nm-g phenotype (see Table S2 in the supplementary material). Annotation of ...
... supplementary material). PCR and SNP markers were generated at each position on linkage group 17 and the markers that showed polymorphisms between C108 and a46 were used for the genetic analysis of 839 F2 individuals with the nm-g phenotype (see Table S2 in the supplementary material). Annotation of ...
Changes in retinoic acid signaling alter otic patterning
... Changes in retinoic acid signaling alter otic patterning Stefan Hans1,2 and Monte Westerfield1,* Retinoic acid (RA) has pleiotropic functions during embryogenesis. In zebrafish, increasing or blocking RA signaling results in enlarged or reduced otic vesicles, respectively. Here we elucidate the mech ...
... Changes in retinoic acid signaling alter otic patterning Stefan Hans1,2 and Monte Westerfield1,* Retinoic acid (RA) has pleiotropic functions during embryogenesis. In zebrafish, increasing or blocking RA signaling results in enlarged or reduced otic vesicles, respectively. Here we elucidate the mech ...
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... development of the sporophyte generation. Genetic analyses showed that imm is a recessive, single-locus Mendelian factor and analysis of gene expression in this mutant indicated that the regulation of a number of life-cycle-regulated genes is specifically modified in imm mutant sporophytes. Thus, IM ...
... development of the sporophyte generation. Genetic analyses showed that imm is a recessive, single-locus Mendelian factor and analysis of gene expression in this mutant indicated that the regulation of a number of life-cycle-regulated genes is specifically modified in imm mutant sporophytes. Thus, IM ...
Signaling Pathways of Heme Oxygenase
... The toxic effects of CO have been known for many years. Since CO binds hemoglobin with higher affinity than O2, O2 delivery to tissues and organs is blocked by this gaseous molecule. More recently, HO-derived CO has been recognized to be an important cellular messenger with various physiological fun ...
... The toxic effects of CO have been known for many years. Since CO binds hemoglobin with higher affinity than O2, O2 delivery to tissues and organs is blocked by this gaseous molecule. More recently, HO-derived CO has been recognized to be an important cellular messenger with various physiological fun ...
Introns Structure Patterns of Variation in Nucleotide Composition in
... regions. In addition, negative correlations among codon positions inside internal coding regions suggest stabilizing selection for a GC-content level that was similar in both species. Finally, the intron/exon architecture was shown to affect all codon positions and reveals a pervasive impact of gene ...
... regions. In addition, negative correlations among codon positions inside internal coding regions suggest stabilizing selection for a GC-content level that was similar in both species. Finally, the intron/exon architecture was shown to affect all codon positions and reveals a pervasive impact of gene ...
FUNCTIONAL INVESTIGATION OF ARABIDOPSIS
... tissues during plant development. That multiple CalS genes are expressed in the same cell type suggests the possibility that CalS complex may be constituted by heteromeric subunits. Five CalS genes were induced by pathogen (Peronospora parasitica, a causal agent of downy mildew) or salicylic acid (S ...
... tissues during plant development. That multiple CalS genes are expressed in the same cell type suggests the possibility that CalS complex may be constituted by heteromeric subunits. Five CalS genes were induced by pathogen (Peronospora parasitica, a causal agent of downy mildew) or salicylic acid (S ...
