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Title: On two statistical elements of gene expression data analysis
Title: On two statistical elements of gene expression data analysis

... comparisons simultaneously. The canonical example comes from the analysis of gene expression; a particular case that I will present concerns the expression of human genes in nasopharyngeal cancer cells comparing cells grouped according to expression of the Epstein-Barr virus. After reviewing some ba ...
compgenomics
compgenomics

... no identify many indels Idea: sequence pairs of sequences at some distance apart from each other ...
messenger RNA (mRNA)
messenger RNA (mRNA)

... ...
Regulation of Gene Expression
Regulation of Gene Expression

... Example: lac operon in E. coli, control genes that code for proteins that break down lactose for food • Lac operons are turned on by lactose and turned ...
Regulation and Expression of Aldehyde Dehydrogenase in Normal
Regulation and Expression of Aldehyde Dehydrogenase in Normal

... commonly associated with the progression of human cancers. Hypermethylation of CpG islands is the most well categorised epigenetic change to occur in tumours. Many CpG islands associated with transcription of a wide variety of genes become aberrantly methylated in tumours. Genes representing all the ...
“bDNA for gene expression in plant and animal tissue”
“bDNA for gene expression in plant and animal tissue”

... “bDNA for gene expression in plant and animal tissue” December 2nd, 2014 at 12:00-1:00pm Genomics bldg. Room 1102A Speaker: Harry Vacek, Quantigene Specialist Please RSVP to [email protected] food will be provided for RSVPs Measure up to 80 genes or 4 RNA targets in 1 sample Imagine if you c ...
Gene Expression (Epigenetics)
Gene Expression (Epigenetics)

... • Transcription initiation complexes also regulate gene expression • Enhancer region upstream from the gene is joined to the transcription initiation complex by activators (proteins) = start transcription • http://www.dnai.org/a/index.html ...
trp operon – a repressible system
trp operon – a repressible system

... Gene regulation in eukaryotes is more complex than it is in prokaryotes because of: – the larger amount of DNA – the organization of chromatin – larger number of chromosomes – spatial separation of transcription and translation – mRNA processing – RNA stability – cellular differentiation in eukar ...
Slide 1
Slide 1

... Non parametric testing (Wilcoxon-Mann-Whitney U-test; p<0.01 for class comparisons with Benjamini correction; p<0.05 for modular analyses with no multiple testing corrections) was used to rank genes based on their ability to discriminate among pre-specified groups of patients. 9,477 genes passing th ...
lecture25_DarkMatter..
lecture25_DarkMatter..

... 3. this union must be coherent, done separately for protein and RNA products, but it does not require that all the products necessarily share a common subsequence concisely summarized as a union of genomic sequences encoding a coherent set of potentially overlapping functional products ...
Genomic and gene expression profiling in malignant hematology
Genomic and gene expression profiling in malignant hematology

... assays in malignant hematology. Microarrays are high throughput tools that have evolved during the past decade. These allow for dissection of all known genes in malignant cells at genomic or transcriptional level in a single experiment. The human genome contains approximately 23,000 protein-coding g ...
Chapter 19: Control of Gene Expression in Eukaryotes
Chapter 19: Control of Gene Expression in Eukaryotes

Chapter 17 - Gene Regulation in Eukaryotes
Chapter 17 - Gene Regulation in Eukaryotes

... 5. Regulation of RNA processing, RNA stability, and translation a. Alternative splicing regulates which exons occur in an RNA transcript, allowing different polypeptides to be made from the same structural gene b. The stability of mRNA influences mRNA concentration c. Double-stranded RNA can silence ...
Functional Characterization of Soybean Transcription Factor
Functional Characterization of Soybean Transcription Factor

What is the most likely path of inheritance?
What is the most likely path of inheritance?

... Coat color is Labrador retrievers is controlled by the inheritance and interaction of two genes. Black color is dominant to chocolate, but yellow Labrador retrievers will be produced if a second dominant gene allowing the ability to express pigment is not inherited. Two black Labrador retrievers, he ...
powerpoint
powerpoint

... ...
Biology Chapter 11- Gene Expression Miss Ventrone
Biology Chapter 11- Gene Expression Miss Ventrone

...  Much more ______________ than prokaryotes  _________________________  Contain genetic information within the ________________ Structure of Eukaryotic Genes  ____________________ site of _______________ ___________________ in DNA and RNA **Some portions remain ____________________ coiled in ____ ...
Chromatin Structure and Gene Regulation
Chromatin Structure and Gene Regulation

Scientific abstract
Scientific abstract

... 200 nucleotides. LncRNAs are not well studied yet and it is a new emerging field. Once it was discovered that these sequences are well conserved lncRNAs were considered as functional RNAs because conservation means that they are constrained due to structural or sequence-specific functions (Ponting, ...
Moderately Repetitive Sequences Code for rRNA Structure and
Moderately Repetitive Sequences Code for rRNA Structure and

... Eukaryotic Transcription & Translation are Compartmentalized ...
Multiple choice questions
Multiple choice questions

... Occurs at the ends of coding regions Can be induced by specific RNA stem-loops Is similar in prokaryotes and in the nucleus of eukaryotes Can involve the action of several proteins Is always linked to translation Can be regulated ...
Eukaryotic Gene Expression ppt
Eukaryotic Gene Expression ppt

Lesson
Lesson

... ...
Gene Regulation
Gene Regulation

... Some genes are regulated (turned off and on) by repressor proteins While others use proteins that enhance the rate of transcription. Operons are generally not found in Eukaryotes. Gene regulation is controlled individually and have regulatory sequences that are much more complex that those of the la ...
12.4 Mutations
12.4 Mutations

... ...
< 1 ... 203 204 205 206 207

Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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