Epigenetic Regulation ofbdnfGene Transcription in the
... changes when using the “unmethylated” primers and vice versa. We also evaluated -tubulin-4 DNA after context exposure or contextual fear conditioning and found no significant alterations in unmethylated -tubulin-4 DNA. Thus, we used unmethylated -tubulin-4 levels for normalization of bdnf DNA met ...
... changes when using the “unmethylated” primers and vice versa. We also evaluated -tubulin-4 DNA after context exposure or contextual fear conditioning and found no significant alterations in unmethylated -tubulin-4 DNA. Thus, we used unmethylated -tubulin-4 levels for normalization of bdnf DNA met ...
Swartzlander_ku_0099D_15051_DATA_1
... males; 7,11-HD in females). D. erecta has a similar profile in that the predominant female CHCs are longer and less saturated than those of the males (Jallon and David 1987). The predominance of 7-T in both sexes of D. simulans is the same in the sister species, D. mauritiana. These patterns of CHC ...
... males; 7,11-HD in females). D. erecta has a similar profile in that the predominant female CHCs are longer and less saturated than those of the males (Jallon and David 1987). The predominance of 7-T in both sexes of D. simulans is the same in the sister species, D. mauritiana. These patterns of CHC ...
The universal reagent for genome tailoring
... control that the remaining loxP site does not create a disturbance in the gene function after the selectable marker is removed. Interestingly, this allele without the marker removal (Fig. 3B) can provide a useful tool for learning more about the function of the gene of interest. If the marker was de ...
... control that the remaining loxP site does not create a disturbance in the gene function after the selectable marker is removed. Interestingly, this allele without the marker removal (Fig. 3B) can provide a useful tool for learning more about the function of the gene of interest. If the marker was de ...
Syntabulin, a motor protein linker, controls dorsal
... ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array formation and ventralization (Cuykendall and Houston, 2009). Cumulatively, these data support the hypothesis that microtubule-dependent ...
... ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array formation and ventralization (Cuykendall and Houston, 2009). Cumulatively, these data support the hypothesis that microtubule-dependent ...
Nonsensemediated decay of glutathione peroxidase 1 mRNA in the
... site, i.e. 105 bp downstream of the codons (Figure 1; data not shown for TGA), and the cellular site of NMD remained cytoplasmic (data not shown). Therefore, GPx1 mRNA is not an exception to the rule for termination codon position within intron-containing genes, which states that nonsense codons loc ...
... site, i.e. 105 bp downstream of the codons (Figure 1; data not shown for TGA), and the cellular site of NMD remained cytoplasmic (data not shown). Therefore, GPx1 mRNA is not an exception to the rule for termination codon position within intron-containing genes, which states that nonsense codons loc ...
Consulta: subjectFacets:"Oviduct" Registros recuperados: 17 Data
... Intra-oviductal administration of RNA obtained from oviducts of estradiol-treated rats resulted in accelerated egg transport (<A HREF="#rios97">Ríos et al., 1997</A>). It is probable that estradiol-induced messenger RNA (mRNA) entered oviductal cells and was translated into the proteins ...
... Intra-oviductal administration of RNA obtained from oviducts of estradiol-treated rats resulted in accelerated egg transport (<A HREF="#rios97">Ríos et al., 1997</A>). It is probable that estradiol-induced messenger RNA (mRNA) entered oviductal cells and was translated into the proteins ...
Genetic regulation of cold-induced albinism in
... 2005). During the last decades, considerable efforts have been made to elucidate regulatory pathways affecting chlorophyll biosynthesis driving such acclimation. Though transcriptome regulation has been considered marginal under resting conditions, several studies reported changes in transcript expr ...
... 2005). During the last decades, considerable efforts have been made to elucidate regulatory pathways affecting chlorophyll biosynthesis driving such acclimation. Though transcriptome regulation has been considered marginal under resting conditions, several studies reported changes in transcript expr ...
Both Polymorphic Variable Number of Tandem Repeats
... alleles. IDDM2 or INS is one of the multiple loci that encode susceptibility to type 1 diabetes, a prototype of human autoimmunity (10,22–24). INS-VNTR situated 5⬘upstream of the INS promoter, is regarded as a causal variant at the locus after a close correlation was found between VNTR haplotypes an ...
... alleles. IDDM2 or INS is one of the multiple loci that encode susceptibility to type 1 diabetes, a prototype of human autoimmunity (10,22–24). INS-VNTR situated 5⬘upstream of the INS promoter, is regarded as a causal variant at the locus after a close correlation was found between VNTR haplotypes an ...
redundancy and regulatory interactions between two
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
Endogenous Cerberus activity is required for anterior head
... oligo was present. This strongly indicates that in the frog embryo, no additional cerberus messages with a different 5′ UTR exist. We tested the ability and specificity of this CerMo to inhibit translation of cerberus mRNA in a cell free transcription/translation system and in Xenopus embryos. Weste ...
... oligo was present. This strongly indicates that in the frog embryo, no additional cerberus messages with a different 5′ UTR exist. We tested the ability and specificity of this CerMo to inhibit translation of cerberus mRNA in a cell free transcription/translation system and in Xenopus embryos. Weste ...
Hox, ParaHox, ProtoHox: facts and guesses
... complexity, and antero-posterior diversification, I propose the following hypothesis for some of the major Metazoan evolutionary transitions (Figure 3b): First, a ProtoHox cluster with two genes was duplicated predating the Cnidarian/Bilaterian transition. Present Cnidarians have clusters that are d ...
... complexity, and antero-posterior diversification, I propose the following hypothesis for some of the major Metazoan evolutionary transitions (Figure 3b): First, a ProtoHox cluster with two genes was duplicated predating the Cnidarian/Bilaterian transition. Present Cnidarians have clusters that are d ...
Evolution of Closely Linked Gene Pairs in
... functional entity, a monocistronic coding sequence of which the expression is controlled by an autonomous promoter. In fact, there is a significant clustering of genes in the mammalian genome where the genes in these clusters show coordinate expression (Hurst et al. 2004; The FANTOM Consortium 2005; ...
... functional entity, a monocistronic coding sequence of which the expression is controlled by an autonomous promoter. In fact, there is a significant clustering of genes in the mammalian genome where the genes in these clusters show coordinate expression (Hurst et al. 2004; The FANTOM Consortium 2005; ...
Confrontation of scabrous expressing and non
... characterized by oversized facets that contain either too many photoreceptors, or 2 or more normal R-cell complements enclosed by only one set of pigment cells (Fig. 2I,J; Baker et al., 1990). Other defects seen in sca− eyes are ommatidia with too few photoreceptor cells, or ommatidia with abnormal ...
... characterized by oversized facets that contain either too many photoreceptors, or 2 or more normal R-cell complements enclosed by only one set of pigment cells (Fig. 2I,J; Baker et al., 1990). Other defects seen in sca− eyes are ommatidia with too few photoreceptor cells, or ommatidia with abnormal ...
no isthmus and pax2.1 in zebrafish tubulogenesis
... During normal zebrafish development, glomerular filtration of blood begins between 40 and 48 hpf (Drummond et al., 1998; Majumdar and Drummond, 1999). no isthmus (noi) homozygotes display severe edema by 48 hpf indicating a failure in osmoregulation and a possible defect in pronephric function (Bran ...
... During normal zebrafish development, glomerular filtration of blood begins between 40 and 48 hpf (Drummond et al., 1998; Majumdar and Drummond, 1999). no isthmus (noi) homozygotes display severe edema by 48 hpf indicating a failure in osmoregulation and a possible defect in pronephric function (Bran ...
PDF
... factor (Abe et al., 2005; Wigge et al., 2005). The resulting complex activates transcription of genes that promote floral development, including AP1, thus triggering the floral transition. Activation of FT by CO is likely to be mediated through interactions with nuclear factor Y proteins (NF-Y) – also ...
... factor (Abe et al., 2005; Wigge et al., 2005). The resulting complex activates transcription of genes that promote floral development, including AP1, thus triggering the floral transition. Activation of FT by CO is likely to be mediated through interactions with nuclear factor Y proteins (NF-Y) – also ...
The daily rhythm of mice
... Coupled to the core loop is a second, stabilizing loop (Fig. 1). Mice deficient for the nuclear receptor REV-ERBa showed a shorter period probably due to dampened amplitude of Bmal1 expression [41]. The REV-ERBa protein bound to the promoter region of the Bmal1 gene in the phase of transcriptional re ...
... Coupled to the core loop is a second, stabilizing loop (Fig. 1). Mice deficient for the nuclear receptor REV-ERBa showed a shorter period probably due to dampened amplitude of Bmal1 expression [41]. The REV-ERBa protein bound to the promoter region of the Bmal1 gene in the phase of transcriptional re ...
View PDF - OSU Biochemistry and Molecular Biology
... required for appendage formation, encodes a homeobox transcription factor and is one of the high-level executives regulated by Hox proteins. The area of Dll expression in the embryo (shown as grey patches) corresponds to sites where in the course of development imaginal discs and, subsequently, appe ...
... required for appendage formation, encodes a homeobox transcription factor and is one of the high-level executives regulated by Hox proteins. The area of Dll expression in the embryo (shown as grey patches) corresponds to sites where in the course of development imaginal discs and, subsequently, appe ...
Conservation and diversification of gene function during mouthpart
... The mandibles are the chewing mouthparts, articulated to the head by two condyles. From the base of the mandibles extend two lobes: the distal incisor lobe and the inner median molar lobe, which are linked by a flexible area (Fig. 5Ai to iv). The setae on the inner periphery of the incisor lobe delim ...
... The mandibles are the chewing mouthparts, articulated to the head by two condyles. From the base of the mandibles extend two lobes: the distal incisor lobe and the inner median molar lobe, which are linked by a flexible area (Fig. 5Ai to iv). The setae on the inner periphery of the incisor lobe delim ...
Distalless and dachshund pattern both plesiomorphic
... (bearing the first walking leg pair or the first and second walking leg pairs). In contrast to these multiple studies of the role of Dll, no functional data are available for dac, hth, or exd in any chelicerate. The most recent addition to the suite of chelicerate study organisms is the harvestman Pha ...
... (bearing the first walking leg pair or the first and second walking leg pairs). In contrast to these multiple studies of the role of Dll, no functional data are available for dac, hth, or exd in any chelicerate. The most recent addition to the suite of chelicerate study organisms is the harvestman Pha ...
In vitro fertilization (IVF) in mammals: epigenetic and developmental
... development does not depend only on a healthy genome. There is an important epigenetic reprogramming during gametogenesis and the preimplantational period of the embryo, especially in imprinted genes, defined by their parental origin [25, 26]. This period has a sensible window to environmental chang ...
... development does not depend only on a healthy genome. There is an important epigenetic reprogramming during gametogenesis and the preimplantational period of the embryo, especially in imprinted genes, defined by their parental origin [25, 26]. This period has a sensible window to environmental chang ...
genomebiology.com
... exons/introns from previously intronic/exonic sequences, respectively), and insertion into first and last exons. However, no extensive analysis has compared the effects of TEs on the transcriptomes of mammals, non-mammalian vertebrates and invertebrates. Results: We analyzed the influence of TEs on ...
... exons/introns from previously intronic/exonic sequences, respectively), and insertion into first and last exons. However, no extensive analysis has compared the effects of TEs on the transcriptomes of mammals, non-mammalian vertebrates and invertebrates. Results: We analyzed the influence of TEs on ...
Translational control of regA, a key gene controlling
... level. First, it was observed that the synthesis of RegA protein lags behind the appearance of the regA mRNA by 4 hours (Kirk et al., 1999). Second, the level of RegA protein is much lower than might be expected from the mRNA level. Third, there are eight potential start codons (AUGs) (Fig. 2) in th ...
... level. First, it was observed that the synthesis of RegA protein lags behind the appearance of the regA mRNA by 4 hours (Kirk et al., 1999). Second, the level of RegA protein is much lower than might be expected from the mRNA level. Third, there are eight potential start codons (AUGs) (Fig. 2) in th ...
DNA supercoiling factor contributes to dosage
... chromosome (Deuring et al., 2000; Corona et al., 2002; Badenhorst et al., 2002). The chromosome defect in the mutant strains is likely to be the result of an imbalance caused by acetylation by MOF leading to a more open chromatin state, without ISWI working toward a more condensed chromatin state (D ...
... chromosome (Deuring et al., 2000; Corona et al., 2002; Badenhorst et al., 2002). The chromosome defect in the mutant strains is likely to be the result of an imbalance caused by acetylation by MOF leading to a more open chromatin state, without ISWI working toward a more condensed chromatin state (D ...