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Genetic polymorphisms among C57BL/6 mouse inbred strains
Genetic polymorphisms among C57BL/6 mouse inbred strains

... Mapping panel, consisting of 1,449 single-nucleotide-polymorphisms (SNPs) that were selected from all 20 mouse chromosomes (approximately 3 SNPs per 5 Mb interval across the genome) and chosen to maximize genetic information across common inbred strains (www.illumina.com). Out of the 1,449 SNPs in t ...
The monogenic primary dystonias
The monogenic primary dystonias

... occurs as a paroxysmal sign in association with other movement anomalies and sometimes seizures. While gross neuropathological changes are absent in most primary dystonias, including the paroxysmal forms, striking morphological alterations are found in some, such as in the X-linked dystonia–parkinso ...
A SMN missense mutation complements SMN2 restoring snRNPs
A SMN missense mutation complements SMN2 restoring snRNPs

... was the same as control animals that had mouse Smn. In addition, there was no obvious phenotype in these animals and they were comparable to animals that possessed mouse Smn (Fig. 3C). Due to the nature of the crosses used to obtain these animals, the mice could be either homozygous for SMN2 (2 copi ...
Inherited epidermolysis bullosa - zum EB
Inherited epidermolysis bullosa - zum EB

... Results: In this latest consensus report, we introduce a new approach to classification (‘‘onion skinning’’) that takes into account sequentially the major EB type present (based on identification of the level of skin cleavage), phenotypic characteristics (distribution and severity of disease activi ...
Determining the Transcription Factor Genes Populating a Fruit Fly
Determining the Transcription Factor Genes Populating a Fruit Fly

... bab2 genes. These transgene lines came from the Vienna Drosophila RNAi Center (Dietzl et al., 2007). The Transgenic RNAi Project lines were derived by use of the VALIUM1 and VALIUM10 vectors which include long dsRNA hairpin (Ni et.al., 2008, 2009), while lines produced from the VALIUM20, VALIUM21, a ...
G6PD Deficiency as Protection Against falciparum
G6PD Deficiency as Protection Against falciparum

... Luzzatto and Mehta (1989) have reached polymorphic frequencies of >.1% in various human populations and are associated with adaptation to falciparum malaria (see below). Some important regional polymorphic variants G6PD A is a normal variant (Class IV) that has 90% of the activity of G6PD B ( Luzzat ...
Leptin regulation of lipid homeostasis: dietary and metabolic
Leptin regulation of lipid homeostasis: dietary and metabolic

... Fig. 1 illustrates our current understanding of the basic signalling pathways emanating from leptin receptors. Leptin binding to its receptors results in receptor dimerization, an apparent prerequisite for signalling (White et al. 1997). Receptor homodimerization of Ob-Rb (long-form receptor) signal ...
Click here for an answer key in Microsoft Word format
Click here for an answer key in Microsoft Word format

... outer barrier of the cell; it forms a barrier between the cytoplasm inside the cell and the environment outside the cell. 2. Semi-permeability, or selective permeability, is the ability to allow only certain molecules in or out of the cell. It is a characteristic of the plasma membrane. 3. The plas ...
Identification of Redeye, a new sleep-regulating protein whose
Identification of Redeye, a new sleep-regulating protein whose

... (the circadian clock) controls the timing, in other words the onset and offset of sleep, whereas process S (the sleep homeostat) regulates sleep duration based on the sleep pressure built up during prior wakefulness (Borbely, 1982). This simple model explains sleep related phenomena, including sleep ...
FREE Sample Here
FREE Sample Here

... OBJ: 1 ...
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PDF

... difference in the role of Hh in otic patterning between amniote and anamniote vertebrates is surprising, as the structure of the inner ear is similar in both groups, except for the presence of the ventrally positioned cochlea, a specialised auditory endorgan, in the amniote ear. Subsequently, howeve ...
Neurospora Spore Killers Sk-2 and Sk
Neurospora Spore Killers Sk-2 and Sk

... be silenced. The resulting ascus is devoid of microtubules and will be arrested before metaphase I. Evidently, the presence of an unpaired copy of a gene is a red flag for mischief, which will alert the silencing system to destroy all transcripts similar to it (Shiu et al. 2001). The MSUD mechanism ...
Product description P018-G1 SHOX-v03 - MRC
Product description P018-G1 SHOX-v03 - MRC

... Gene structure and Transcript variants: SHOX spans 35 kb of the pseudoautosomal region 1 (PAR1) located on Xp22.33/Yp11.32. The Genbank chromosomal sequence is NG_009385.1. Two major transcript variants have been described: http://www.ncbi.nlm.nih.gov/gene/6473. SHOX transcript variant 1 (NM_000451. ...
The Center for Organogenesis | University of Michigan, Ann Arbor
The Center for Organogenesis | University of Michigan, Ann Arbor

... cell fate decisions in numerous processes (Uwanogho et al., 1995). Sox1, Sox2 and Sox3 are all expressed in the lens (Kamachi et al., 1998). Sox2 and Sox3 expression in the early lens placode is dependent on the optic vesicle and this implies that they are responsive to inductive signals (Kamachi et ...
Polyploidy
Polyploidy

... abnormal formation of vocal mechanisms. ...
Renal pelvis - Echo ED: Diagnostic Medical Sonography Education
Renal pelvis - Echo ED: Diagnostic Medical Sonography Education

... What is multicystic dysplastic kidney and show several images of it. Explain the scanning technique for imaging the kidneys with ultrasound. Include in your answer imaging the renal ...
DMSM 105 Urinary Tract Part 1 - Echo ED: Diagnostic Medical
DMSM 105 Urinary Tract Part 1 - Echo ED: Diagnostic Medical

... What is multicystic dysplastic kidney and show several images of it. Explain the scanning technique for imaging the kidneys with ultrasound. Include in your answer imaging the renal ...
Mutational Analysis of the Drosophila Sister-Chromatid
Mutational Analysis of the Drosophila Sister-Chromatid

... were isolated by their failure to complement md' (MIYAZAKI and ORR-WEAVER1992). For all tests requiring a chromosome for which the ord gene was deleted, the deficiency chromosome Df(ZR)W7370 was used (BICKELet al. 1996). The isoX/Y, cv v f car, compound-X and compound-XY stocks were described in KER ...
Asymmetries in Retrieval of Gene Function Information
Asymmetries in Retrieval of Gene Function Information

... of the source followed by a slash followed by an accession number and can be searched with one or both components, e.g., genbank [si], AF001892 [si], genbank/AF001892 [si]. The SI field and the Entrez sequence database links are not linked. The PubMed links to these databases are created from the re ...
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PDF

... wild-type heart-stage embryos is expressed throughout the cotyledon primordia (Long and Barton, 1998; Schoof et al., 2000), was detected around the whole apical circumference of gnom embryos (Fig. 1D,H), and was mainly restricted to the epidermis. This aberrant marker expression reflects the failure ...
Yersinia pestis Biofilm in the Flea Vector and Its Role
Yersinia pestis Biofilm in the Flea Vector and Its Role

Observations on the New Rh Agglutinin Anti-f
Observations on the New Rh Agglutinin Anti-f

... Per- ...
Section 1 The application - Office of the Gene Technology Regulator
Section 1 The application - Office of the Gene Technology Regulator

GENETIC AND MOLECULAR ANALYSIS OF THE garnet EYE
GENETIC AND MOLECULAR ANALYSIS OF THE garnet EYE

... A critical test of this model requires molecular cloning and analysis of the individual members of the transport group of eye colour genes. Preliminary molecular analysis of the garnet gene is reported in chapter two. The garnet gene is expressed in many different tissues at different stages in deve ...
Here - Orrery Software
Here - Orrery Software

... PSoup and Emergent Behavior -------------------------------------------------------------------------------------51 PSoup and Biased Mutations ----------------------------------------------------------------------------------------55 Advanced PSoup --------------------------------------------------- ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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