Download Molecluar Genetics Key

Molecular Genetics
Mastery Assignment Example Key
1.
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What was Rosalind Franklin’s contribution to the discovery of DNA structure?
(A)
(B)
(C)
(D)
She isolated the agent behind the transforming principle.
She made important discoveries about the properties of nucleic acids.
She photographed DNA using X-rays.
She produced a structural model of DNA.
2.
Which describes the composition of a chromosome?
v
(A)
(B)
(C)
(D)
3.
Which structure below is represented by A?
v
4.
v
5.
v
(A)
(B)
(C)
(D)
one very long DNA molecule
one very long gene molecule
thousands of protein molecules
thousands of RNA molecules
hydrogen bond
nitrogen base
phosphate
sugar
Which step in DNA replication involves the DNA unwinding and unzipping?
(A)
(B)
(C)
(D)
elongation
initiation
proofreading and correction
termination
If the sequence of bases in one strand of DNA is GGC TAA, what is the sequence in the
complementary strand?
(A)
(B)
(C)
(D)
AAT CGG
CCG ATT
GGC TAA
TTU GCC
Amino Acids coded by RNA Codons
Second Letter
First
Letter
U
C
A
G
Third
Letter
phenylalanine
serine
tyrosine
cysteine
U
phenylalanine
serine
tyrosine
cysteine
C
leucine
serine
STOP
STOP
A
leucine
serine
STOP
tryptophan
G
leucine
proline
histidine
arginine
U
leucine
proline
histidine
arginine
C
leucine
proline
glutamine
arginine
A
leucine
proline
glutamine
arginine
G
isoleucine
threonine
asparagine
serine
U
isoleucine
threonine
asparagine
serine
C
isoleucine
threonine
lysine
arginine
A
START/
methionine
threonine
lysine
arginine
G
valine
alanine
aspartate
glycine
U
valine
alanine
aspartate
glycine
C
valine
alanine
glutamate
glycine
A
valine
alanine
glutamate
glycine
G
U
C
A
G
6.
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7.
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8.
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Using the RNA codon table above, which amino acids are coded by the DNA sequence
GCT AAT?
(A)
(B)
(C)
(D)
alanine-valine
arginine-leucine
serine-proline
valine-glycine
An anti-sense strand of DNA has bases ATC GAT CCG. Which is the correct sequence
for bases on tRNA anticodons coded from this DNA?
(A)
(B)
(C)
(D)
AUC GAU CCG
TAG CTA GGC
UAG CUA GGC
CGG ATC GAT
Which type of mutation involves a part of one chromosome changing place with a part of
another chromosome?
(A)
(B)
(C)
(D)
duplication
inversion
nondisjunction
translocation
B iology 3201 August 2007
Page 2 of 17
9.
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10.
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Which diagnostic technique enables direct observation of a developing fetus?
(A)
(B)
(C)
(D)
amniocentiesis
chorionic villi sampling
fetoscopy
genetic markers
Which technique allows for DNA fragments to be separated into bands forming a DNA
fingerprint?
(A)
(B)
(C)
(D)
cloning
DNA amplification
DNA sequencing
gel electrophoresis
(b)
A mutation changed a DNA template sequence from AGC CCG GCA TTG to
AGC CCG GGC ATT G.
11.
%
i)
What type of gene mutation caused this change?
Insertion - one nucleotide base added at position between bases 7 and 8.
(1 mark)
ii)
Using the codon table provided on page 10, show how the polypeptide
sequence changes from the original to the mutated strand.
Arginine changes to proline - 1 mark
Asparagine changes to “stop” codon - 1 mark
B iology 3201 August 2007
Page 4 of 17