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PCL: Cerebral Cortex Circle of willis Sensory Pathways Dorsal The dorsal column conducts proprioception, vibration, some light touch and twopoint discrimination. Below the level of a lesion, these are diminished. Tingling, electric-shock-like sensations, clumbsiness, numbness and band-like sensations can be felt. In a cervical cord lesion, Lhermitte’s phenomenon can occur. In Lhermitte’s phenomenon, electric-shock sensations radiate down the trunk and limbs on neckflexion. Spinothalamic (anterolateral) A lesion within the spinothalamic tracts of the cord that causes conduction to fail produces changes in pain and temperature sensation below its level. External lesions produce changes to pain and temperature sensation beginning in the lower limbs and ascending to the level of the lesion. In a syrinx, a cavity in the centre of the spine, the lower limbs and sacral areas can be spared. (Kumar) UMN vs LMN Upper motor neurons: an upper motor neuron originates in the cerebral cortex or brainstem and conducts nerve impulses down to the appropriate spinal level. An upper motor neuron lesion is also known as a pyramidal lesion. Lower motor neurons: these carry nerve impulses from the spinal cord (or brainstem for cranial nerves) to the muscle Decussation: the crossing over of upper motor neurons Suppose that left-sided facial weakness arises. Where could this pathology be? 1. Left side lower-motor neuron 2. Right side upper motor neuron How could these causes be differentiated from each other? A left-side lower motor neuron lesion will paralyse the entire face. However, at least theoretically, an upper motor neuron lesion will spare the upper part of the contralateral side. This is because the upper facial muscles are supplied by both the left and right cortex. (You can see that although most neurons cross over, some instead supply the ipsilateral forehead) Refs: Kumar & Clark Clarke, queen square textbook