Download SI Worksheet 12

Lecture 12 - Gene expression
Short Answer
1. What is gene expression
2. What is gene expression important
Fill in the Blank
a. Altering a protein to form an active final product
_____ 1. First step in RNA splicing
_____ 2. Second step in RNA splicing
b. Action of inhibitors that may block synthesis of protein
_____ 3. Alternative RNA splicing
_____ 4. RNA interference
_____ 5. Inhibition of translation
_____ 6. Activation of finished protein
c. Joining exons in different ways to produce more than one
form mRNA message
kind of mRNA ( and polypeptide ) from a single gene
d. Removal of noncoding introns from RNA
e. Joining of exons to produce mRNA
f. Binding of microRNA (miRNA) to mRNA, blocking
translation
1. ________________ are pieces of
DNA that can relocate
2. ________________ also known as master genes
3. ________________ is something in addition do DNA that controls
gene expression
4. Gene expression through attachment of acetyl groups to histones is
know as ________________
5. Insulin is an example of the importance of this process of gene
expression know as _____________________
6. The attachment of ________________ is a way to prevent
gene expression
7. ______________ is when a X chromosome is randomly silenced
8. The process of removing introns and exons from an mRNA is
an example of ___________________
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a. homeotic genes
b. jumping genes
c. epigenetics
d. protein folding
e. RNA splicing
f. Inactivation of X
chromosome
g. acetylation of
histones
h. cell signaling
i. environment
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Lecture 12 - Gene expression
Multiple Choice
1. Your muscle and bone cells are different because
a. they contain different sets of genes
b. they are differentiated
c. they contain different operons
d. different genes are switched on and off in each
e. they contain different histones
2. DNA packing - the way DNA is folded into chromosomes- affects gene expression by
a. controlling access to DNA
b. positioning related genes near each other
c. protecting DNA from mutations
d. enhancing recombination of genes
e. allowing “unpacked” genes to be eliminated from the genome
3. After an mRNA molecule is transcribed from a eukaryotic gene, portions called _____
are removed and the remaining _______ are spliced together to produce an mRNA
molecule with a continuous coding sequence
a. operators....promoters
b. exons....introns
c. silencers....enhancers
d. introns....exons
e. promoters....operators
4. Which of the following mechanisms of gene regulation operates after mRnA
transcription but before translation of mRNA into protein?
a. mRNA splicing
b. DNA packing
c. repressors and activators
d. protein degradation
e. all of the above
5. Homeotic genes
a. are responsible for the cellular changes that occur in cancer.
b. coordinate development by controlling other genes
c. are found only in certain cells
d. are any genes transferred from cell to cell by viruses
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Lecture 12 - Gene expression
e. repair DNA and defend against mutations
6. In a eukarytoe, which of the following may block gene expression by binding to DNA?
a. an operon
b. a histone
c. an enhancer
d. a promoter
e. a silencer
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